Time course of cardiac structural and functional changes in babies in the first year of life who have sustained transient myocardial ischemia in the early neonatal period

Purpose. To assess frequency and severity of myocardial damage in premature infants with transient myocardial ischemia in the early neonatal period.Materials and methods. The study includes 73 newborns of a gestational age of 31–36 weeks with respiratory failure and oxygen dependence in the first 2 hours of life. Newborns are divided into groups: Group 1: classic electrocardiographic criteria of transient myocardial ischemia and an increase in the level of troponin I in the blood; Group 2: electrocardiographic criteria for transient myocardial ischemia and a normal level of troponin I; Group 3: no ECG changes and normal troponin I level. We assessed blood gases, conducted electrocardiography, determined troponin I in the blood on the 1st and 7th day of life, assesses duration of oxygen therapy in all the children.Results. Group I: troponin I concentration on the 7th day of life – 0.415 [0.222; 0.639] ng/ml, Group II – 0.073 [0.051; 0.104] ng/ml and Group III – 0.017 [0.006; 0.051] ng/ml. Transient myocardial ischemia was detected in 41% of examined patients, and destructive myocardial changes – in 21.9%. An analysis of the gas composition of blood in the first 2 hours demonstrated that there was a significant predominance of the level of bases in the children of Group I. The duration of artificial ventilation in children of Group I was 56 [3; 96] hours, exceeding the indicators of children of Group II (9 [8; 11]) by 5 times, and Group III (20.5 [13; 72]) – by 2.5 times. Also newborns in Group I experienced a maximum need for oxygen therapy through a mask.Conclusion. 21.9% of premature infants experience destructive myocardial changes against the background of transient myocardial ischemia; newborns with transient myocardial ischemia and destructive changes have a significantly more pronounced metabolic acidosis in the first hours of life and a longer need for oxygen therapy.

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SUPRAVENTRICULAR TACHYCARDIA WOLFF-PARKINSON-WHITE SYNDROME IN CHILDREN OF THE REPUBLIC OF BELARUS: AGE AND SEX CHARACTERISTICS, IDENTIFICATION, ELECTROPHYSIOLOGICAL STRUCTURE

Medical Journal ◽

10.51922/1818-426x.2021.4.110 ◽

2021 ◽

pp. 110-113

Author(s):

Strogiy V.V. ◽

◽

Zasim E.V. ◽

Drozdovsky K.V. ◽

Kadochkin V.O. ◽

...

Keyword(s):

Neonatal Period ◽

Electrophysiological Study ◽

Conduction System ◽

Sex Characteristics ◽

First Year ◽

Depth Study ◽

The Republic ◽

First Year Of Life ◽

Supraventricular Tachycardias ◽

Wolff Parkinson White Syndrome

The goal is to establish the frequency of supraventricular tachycardias in children of the Republic of Belarus, to determine the structure and characteristics of these rhythm disturbances. An in-depth study of the properties of the conduction system of the heart was carried out by performing in the course of the esophageal electrophysiological study 108 children. A more rare detection of SVT in children in the neonatal period, in the first year of life and maximum detection at the age of 17 years, a comparatively rare finding (11.8 %) of concomitant pathology in children with SVT.

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Adaptive capabilities of newborns depending on the conditions of intrauterine development

Kazan medical journal ◽

10.17816/kazmj62183 ◽

1982 ◽

Vol 63 (4) ◽

pp. 5-7

Author(s):

E. A. Efimova ◽

S. L. Nesterov ◽

N. L. Yashina ◽

T. K. Shakurova ◽

V. A. Novikova ◽

...

Keyword(s):

Blood Cells ◽

Neonatal Period ◽

Preventive Therapy ◽

First Year ◽

Children At Risk ◽

Intrauterine Development ◽

Adaptive Capabilities ◽

First Year Of Life ◽

Adaptive Reactions

Clinical, cytochemical, and rheological features of the neonatal period were studied in 460 children from mothers suffering from rheumatism or having suffered late toxicosis of pregnant women. On the basis of impaired adaptive reactions, changes in the enzymatic spectrum of blood cells and disorders of microcirculatory mechanisms, children at risk were identified. 50 of them underwent preventive therapy in the neonatal period. The follow-up indicates a lower infectious index during the first year of life in children who received preventive therapy.

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Neurodevelopmental Outcome during the First Year of Life in Preterm Infants after Supplementation of a Prebiotic Mixture in the Neonatal Period: A Follow-Up Study

Neuropediatrics ◽

10.1055/s-0033-1349227 ◽

2013 ◽

Vol 45 (01) ◽

pp. 022-029 ◽

Cited By ~ 11

Author(s):

Natalie LeCouffe ◽

Elisabeth Westerbeek ◽

Petra van Schie ◽

Veronique Schaaf ◽

Harrie Lafeber ◽

...

Keyword(s):

Preterm Infants ◽

Neonatal Period ◽

Neurodevelopmental Outcome ◽

First Year ◽

Follow Up Study ◽

First Year Of Life

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First-Year Mortality among Infants with Facial Clefts

The Cleft Palate-Craniofacial Journal ◽

10.1597/1545-1569_1992_029_0451_fymaiw_2.3.co_2 ◽

1992 ◽

Vol 29 (5) ◽

pp. 451-455 ◽

Cited By ~ 8

Author(s):

Philippe P. Hujoel ◽

Anne-Marie Bollen ◽

Beth A. Mueller

Keyword(s):

Death Certificate ◽

Neonatal Period ◽

Birth Certificate ◽

Fold Increase ◽

Elevated Risk ◽

First Year ◽

Facial Cleft ◽

Facial Clefts ◽

Different Types ◽

First Year Of Life

Children born with a facial cleft are not thought to be at a greater risk for infant mortality than are those without congenital anomalies. The purpose of this study was to investigate whether the presence of a facial cleft alone or its coexistence with other anomalies increases a child's risk for dying. Birth and death certificate data from Washington State for the years 1984 to 1988 were linked for infants who died before 1 year of age. Mortality rates for different types of facial clefts and for births without noted abnormalities were compared. Relative to infants with no diagnosed abnormalities noted in the birth certificate, infants with facial clefts without other abnormalities have a 3.7 fold increased odds for dying during their first year of life. This elevated risk for dying was fairly consistent during the first year of life. When facial clefts are associated with other abnormalities there is an 82.3 fold increase in odds for mortality during the first year of life. This elevated risk is highest during the neonatal period; 77% of all deaths occurred during the first 27 days. It is concluded that infants with facial clefts with or without associated anomalies have a significantly increased mortality risk when compared to infants without any diagnosed abnormalities at birth.

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Indagine sulla mortalità dei gemelli nel primo anno di vita: Ricerca anagrafica su 848 gemelli nati a Catania

Acta geneticae medicae et gemellologiae ◽

10.1017/s1120962300016280 ◽

1963 ◽

Vol 12 (3) ◽

pp. 298-307

Author(s):

Antonino Fiumara

Keyword(s):

Neonatal Mortality ◽

Critical Period ◽

Neonatal Period ◽

First Year ◽

Still Birth ◽

Low Degree ◽

Birth Records ◽

First Year Of Life

SUMMARYA survey has been made of the birth records of 846 twins (415 pairs and 6 sets of triplets) born in Catania between January 1st, 1959 and May 31st, 1962, with the purpose of establishing the degree of mortality in twins in the first year of life. The results indicate a low degree of still-birth (5%). Identifying the neonatal period with the first week of life, the neonatal mortality is of 8.9%. This percentage undergoes a little reduction (1.9%) when we consider as neonatal period just the first day of life, the twin mortality being lower in the subsequent days of the first week. Except that of the 1st day, the higher frequency of mortality (19%) occurs between the 12th and the 16th day, which is considered a critical period in the first month of life in twins. In the remaining 11 months of the year the mortality degre is low (51 deaths in 680 twins survived to the first month). At the end of the year in 63.1% of the considered pairs both twins were still alive. In six of the 43 pairs with both components dead, both twins died between the 13th and the 25th day, with an interval of 24 hours. The spontaneous death of twin pairs, occurring sometimes simultaneously or with a brief interval in the first month of life, may give rise to judiciary mistakes.

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Letter to the Editor

PEDIATRICS ◽

10.1542/peds.93.6.1021b ◽

1994 ◽

Vol 93 (6) ◽

pp. 1021-1022

Author(s):

Brian S. Carter

Keyword(s):

Neonatal Period ◽

Early Infancy ◽

First Year ◽

Significant Percentage ◽

Letter To The Editor ◽

Neonatal Circumcision ◽

First Year Of Life

It is important to know the data that Wiswell and associates have compiled and reported concerning circumcision in children after the neonatal period.1 Of interest would be whether or not a significant percentage of parents who sought late circumcision for their children might have chosen neonatal circumcision with more adequate counselling, or perhaps sought the procedure in early infancy if such an option existed? It appears that only 20% of infants received late circumcision during the first year of life.

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Case-control study on infant mortality in Southern Brazil

Revista de Saúde Pública ◽

10.1590/s0034-89102006000200009 ◽

2006 ◽

Vol 40 (2) ◽

pp. 240-248 ◽

Cited By ~ 11

Author(s):

Karina Giane Mendes ◽

Maria Teresa Anselmo Olinto ◽

Juvenal Soares Dias da Costa

Keyword(s):

Multivariate Analysis ◽

Infant Mortality ◽

Case Control Study ◽

Neonatal Period ◽

Case Control ◽

Infant Mortality Rate ◽

First Year ◽

Southern Brazil ◽

First Year Of Life ◽

Control Study

OBJECTIVE: To identify risk factors associated with infant mortality and, more specifically, with neonatal mortality. METHODS: A case-control study was carried out in the municipality of Caxias do Sul, Southern Brazil. Characteristics of prenatal care and causes of mortality were assessed for all live births in the 2001-2002 period with a completed live-birth certificate and whose mothers lived in the municipality. Cases were defined as all deaths within the first year of life. As controls, there were selected the two children born immediately after each case in the same hospital, who were of the same sex, and did not die within their first year of life. Multivariate analysis was performed using conditional logistic regression. RESULTS: There was a reduction in infant mortality, the greatest reduction was observed in the post-neonatal period. The variables gestational age (<36 weeks), birth weight (<2,500 g), and 5-minute Apgar (<6) remained in the final model of the multivariate analysis, after adjustment. CONCLUSIONS: Perinatal conditions comprise almost the totality of neonatal deaths, and the majority of deaths occur at delivery. The challenge for reducing infant mortality rate in the city is to reduce the mortality by perinatal conditions in the neonatal period.

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