Сhorionic bump: analysis of 16 cases and literature review

2018 ◽  
Author(s):  
N.A. Altynnik, M.V. Medvedev, Å.G. Voytuk
Keyword(s):  
Prenatal Diagnosis ◽  
High Risk ◽  
Literature Review ◽  
Risk Group ◽  
First Trimester ◽  
High Risk Group ◽  
Prenatal Ultrasound ◽  
Ultrasound Diagnosis ◽  
Threatened Miscarriage ◽  
Dynamic Ultrasound

Sixteen cases of prenatal ultrasound diagnosis of chorionic bump at 6–29 weeks of gestation, as well as an analysis of the literature covering 97 cases of prenatal diagnosis of chorionic bump is presented. All cases of chorionic bump was isolated. In 14 (87.5 %) cases the outcome of pregnancy was favourable, in 2 (12.5 %) cases were poor outcome. Сhorionic bump on first-trimester sonography is not necessarily associated with a guarded prognosis, but it condition is recommended to assign the patient to the high-risk group of a threatened miscarriage and ensure careful dynamic ultrasound observation.

scholarly journals Cohort profile: targeted antenatal screening for haemoglobinopathies in Basel

BMJ Open ◽  
2020 ◽  
Vol 10 (7) ◽  
pp. e035735
Author(s):  
Gabriela Amstad Bencaiova ◽  
Franziska Geissler ◽  
Irene Hoesli
Keyword(s):  
High Risk ◽  
Pregnant Women ◽  
Risk Group ◽  
Iron Status ◽  
First Trimester ◽  
High Risk Group ◽  
University Hospital ◽  
Pregnancy Cohort ◽  
Haemoglobin Variant ◽  
Adverse Pregnancy

PurposeThe pregnancy cohort was established to examine the prevalence and variety of haemoglobinopathies in a high-risk group of pregnant women.ParticipantsThe pregnancy cohort is located in the Department of Obstetrics and Antenatal Care, University Hospital of Basel. The pregnant women were recruited in the first trimester between June 2015 and May 2019. Family origin questionnaires were used to screen pregnant women for the risk of a haemoglobin variant. Based on the questionnaire, pregnant women were divided into two groups: women with a high risk and women with a low risk of a haemoglobin variant. In women with a high risk, red blood cell indices, iron status and chromatography were conducted.Findings to date1785 pregnant women were recruited. Out of the 1785 women, 929 were identified as a part of the high-risk group. Due to the missing data of 74 pregnant women with a high risk, the final analysis was conducted in the remaining 855 women. The prevalence of haemoglobinopathies in the high-risk group was 14.5% (124/855).Future plansThis cohort will be used to: (1) implement the screening in prenatal care in Basel; (2) recommend the screening among pregnant women with a high risk of a haemoglobin variant in Switzerland; (3) improve prenatal and neonatal care in patients with a haemoglobin variant; (4) examine adverse pregnancy outcomes in women with a haemoglobin variant and (5) reduce maternal and neonatal morbidity and mortality in the future.Trial registration numberClinicalTrials.gov Registry (NCT04029142).

scholarly journals Ultrasound elastography capabilities in studying uterine cerviх state in pregnant women of high-risk group in the first trimester of pregnancy

2016 ◽  
Vol 97 (4) ◽  
pp. 656-661
Author(s):  
M G Tukhbatullin ◽  
K V Yanakova
Keyword(s):  
High Risk ◽  
Pregnant Women ◽  
Chromosomal Abnormality ◽  
Chromosomal Abnormalities ◽  
Ultrasound Examination ◽  
Risk Group ◽  
First Trimester ◽  
High Risk Group ◽  
Control Group ◽  
Significant Difference

Aim. To study capabilities of quantitative elastographic study to assess the elasticity of the uterine cervix in women with a fetal chromosomal abnormality in the first trimester of pregnancy.Methods. 230 pregnant women of high-risk group at 11-13.6 weeks of pregnancy (parietal-coccygeal length 45-84 mm) were included in this study. The first group consisted of 213 women without fetal pathology. The second group included 17 women, in whose fetuses different chromosomal abnormalities were detected. In ultrasound examination of pregnant women in the I trimester of pregnancy, in addition to standard methods of examination, quantitative cervical elastography was performed.Results. According to results of quantitative elastography in 14 (82.35%) out of 17 pregnant women (second group) one or another degree of the cervical tissue softening was found, and 3 (17.64%) pregnant women with fetal chromosomal pathology had stiff cervix (all 3 cases with Down syndrome). In the control group in 10 (4.7%) of 213 pregnant women relatively soft cervix was identified, and in 203 (95.3%) women cervical density was higher than the myometrial density. A statistically significant difference between the indices of SWE-Ratio in groups was revealed. Quantitative elastography, as a diagnostic test predicting the risk of miscarriage due to chromosomal abnormalities, has a high sensitivity (84.38%) and even higher specificity (95.26%) of negative predictive value 97.57%.Conclusion. Quantitative elastography reveals a significant decrease in the cervical elasticity (softening) in pregnant women with fetal chromosomal abnormality in the I trimester of pregnancy, which allows us to recommend this method of ultrasound examination as an additional marker for early diagnosis of miscarriage due to fetal chromosomal abnormality.

Prenatal diagnosis of OEIS complex in the first trimester of gestation: analysis of the two clinical cases

2017 ◽  
Author(s):  
O.V. Chursina, T.V. Yudintseva
Keyword(s):  
Prenatal Diagnosis ◽  
Imperforate Anus ◽  
First Trimester ◽  
Prenatal Ultrasound ◽  
Ultrasound Diagnosis ◽  
Diagnosis And Prognosis ◽  
Complex Detection ◽  
Diagnostic Complex ◽  
Early Diagnostic ◽  
Clinical Cases

The 2 cases prenatal ultrasound diagnosis of OEIS complex (omphalocele (O) + exstrophy of the cloaca (E) + imperforate anus (I) + spinal defect (S)) in the first trimester are presented. The problems of differential prenatal diagnosis and prognosis, possibility of early diagnostic complex detection are discussed.

Prenatal ultrasound diagnosis of rare lethal syndromes on the example of four cases and review of literature

2019 ◽  
Author(s):  
N.A. Àltynnik, M.V. Kubrina
Keyword(s):  
Prenatal Diagnosis ◽  
First Trimester ◽  
Prenatal Ultrasound ◽  
The Body ◽  
Ultrasound Diagnosis ◽  
Review Of Literature ◽  
Distinctive Features ◽  
Ultrasound Diagnostics

Four cases of prenatal ultrasound diagnostics of rare lethal complexes diagnosed in the first trimester of gestation are presented. The nuclear signs of the anomaly of the stem of the body and the OEIS-complex are discussed. The difficulties of early ultrasound prenatal diagnosis, similarity and distinctive features characteristic of both complexes are analyzed.

Prenatal ultrasound diagnosis of pelvic tumors. I. Sacrococcygeal teratomas. Literature review

2019 ◽  
Author(s):  
I.V. Tikhonenko
Keyword(s):  
Prenatal Diagnosis ◽  
Literature Review ◽  
Mode Of Delivery ◽  
Prenatal Ultrasound ◽  
Ultrasound Diagnosis ◽  
Ultrasound Images ◽  
Pelvic Tumors ◽  
Different Types

Literature review on ultrasound prenatal diagnosis of sacrococcygeal teratomas, including complications, prognosis, management and time and mode of delivery is presented. Ultrasound images of different types of sacrococcygeal teratomas are demonstrated.

Real possibilities of early prenatal diagnosis of coronary-right ventricular fistula

2020 ◽  
Author(s):  
O.L. Galkina
Keyword(s):  
Prenatal Diagnosis ◽  
Right Ventricular ◽  
First Trimester ◽  
Prenatal Ultrasound ◽  
Ultrasound Diagnosis

Experience of prenatal ultrasound diagnosis of coronary-right ventricular fistula at first trimester of gestation is presented

scholarly journals The prevalence of thyroid disorders during early pregnancy in China: the benefits of universal screening in the first trimester of pregnancy

2011 ◽  
Vol 164 (2) ◽  
pp. 263-268 ◽  
Author(s):  
Weiwei Wang ◽  
Weiping Teng ◽  
Zhongyan Shan ◽  
Sen Wang ◽  
Jianxin Li ◽  
...  
Keyword(s):  
High Risk ◽  
Pregnant Women ◽  
Early Pregnancy ◽  
Risk Group ◽  
First Trimester ◽  
Reference Intervals ◽  
Case Finding ◽  
High Risk Group ◽  
Specific Reference ◽  
Thyroid Disorders

ContextMaternal thyroid disorders during early pregnancy can influence pregnancy outcome and fetal development. The recent Endocrine Society Clinical Practice Guideline recommends a case-finding approach in which pregnant women who are at high risk for developing thyroid disease are tested.ObjectiveThe purpose of this study was to use the first trimester-specific reference intervals of thyroid-related hormones to explore the prevalence of thyroid dysfunction during early pregnancy and to analyze effectiveness of different screening strategies.DesignA multicenter cohort study.MethodA total of 2899 pregnant women were enrolled in this study during their first trimester of gestation. Levels of TSH, free thyroxine, free triiodothyronine, and thyroid peroxidase antibodies (TPOAb) were measured and thyroid disorders of pregnant women were diagnosed based on the first trimester-specific reference intervals.ResultsThe prevalence of hypothyroidism was significantly higher in the high-risk group than in the non-high-risk group (10.9 vs 7.0%, χ2=7.1, P=0.008). The prevalence of hyperthyroidism was not significantly different between the high-risk group and the non-high-risk group (2.7 vs 1.6%, χ2=2.27, P=0.13). Elevated levels of TPOAb and a personal history of thyroid disease increased the risk of thyroid dysfunction.ConclusionsA case-finding strategy for screening thyroid function in the high-risk group would miss about 81.6% pregnant women with hypothyroidism and 80.4% pregnant women with hyperthyroidism.

scholarly journals Embolic myocardial infarction. Literature review and own research results

2020 ◽  
Vol 19 (3) ◽  
pp. 2302
Author(s):  
S. A. Boldueva ◽  
M. V. Ryzhikova ◽  
D. V. Oblavatckii
Keyword(s):  
Myocardial Infarction ◽  
High Risk ◽  
Literature Review ◽  
Diagnostic Criteria ◽  
Clinical Experience ◽  
Antithrombotic Therapy ◽  
Risk Group ◽  
Myocardial Revascularization ◽  
High Risk Group ◽  
Common Causes

Patients with embolic myocardial infarction (MI) represent a high-risk group and, accordingly, require special attention of clinicians. This article discusses the most common causes of MI, related diagnostic criteria, antithrombotic therapy, and myocardial revascularization in this category of patients. The data of own clinical experience are also given.

The case of prenatal ultrasound diagnosis of intrapericardial teratoma with successful surgical treatment

2019 ◽  
Author(s):  
N.V. Mostova
Keyword(s):  
Prenatal Diagnosis ◽  
Surgical Treatment ◽  
Caesarean Section ◽  
Histological Analysis ◽  
Surgical Care ◽  
Prenatal Ultrasound ◽  
Ultrasound Diagnosis ◽  
Dynamic Ultrasound

Case of prenatal ultrasound diagnosis of intrapericardial teratoma at 32 weeks of gestation is presented. Pregnancy was carried out with dynamic ultrasound control and proceeded without complications. At 37 weeks of gestation caesarean section was made. The child received a successful surgical care for 8 days of life. The prenatal diagnosis was confirmed on operation and histological analysis.

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