scholarly journals Blood Transfusion Services and Blood Safety of Blood Banks In Ben-Suef Governorate

2021 ◽  
Vol 2 (1) ◽  
pp. 56-65
Author(s):  
Doaa Mahmoud Khalil ◽  
El-Morsy Ahmed El-Morsy ◽  
Hesham Ahmed Nafady ◽  
Lamiaa Saleh
2020 ◽  
Vol 8 (4) ◽  
pp. 86-88
Author(s):  
Usman Waheed ◽  
Naveed Ahmed ◽  
Wafa Hussain ◽  
 Akhlaaq Wazeer ◽  
Noor e Saba ◽  
...  

Pakistan’s blood transfusion system is regulated by federal and provincial legislation, adopted since 1997. The Azad Jammu and Kashmir (AJK) is one of the autonomously administered territories of Pakistan. The AJK’s blood safety act came out in 2003, to regulate the blood transfusion services but remained ineffective for the next decade due to no implementation. During the period 2014-2017, the AJK government sought technical assistance from the Islamabad Blood Transfusion Authority and initiated the implementation of blood safety legislation in the state of AJK through the AJK Blood Transfusion Authority. The AJK BTA identified and inspected 64 blood banks with a total annual blood collection of 30,833. The majority (75%) of the blood banks were in NGO/private sector while the remaining 25% belonged to the public sector. Only six blood banks fulfilled the minimum criteria of licensing set by the AJK BTA. As a result of this ground-breaking work, the AJK became the second region of the country (after Islamabad Capital Territory) to have completed a mapping and inspection exercise in the entire State. This will go a long way in the consolidation of blood transfusion services in AJK.


2021 ◽  
Vol 2 (1) ◽  
pp. 46-50
Author(s):  
Bagus Triatmojo

HIV cases in Jepara District in recent years have demanded the handling of several aspects simultaneously including the Blood Transfusion Unit (BTU). HIV can be transmitted through blood transfusion or other blood products. BTU of PMI Jepara Regency carries out recruitment of voluntary donor from Jepara society. The HIV examination as part of an IMLTD screening test is done for safety of donor blood. The HIV examination in all donor blood uses rapid and elisa method. Examination results are stated as reactive and non reactive. Research objective to find out the description of HIV examination results in donor blood at the BTU of PMI Kabupaten Jepara in 2019. Research method the research type was descriptive using records of donor data at BTU of PMI Kabupaten Jepara in 2019. The examination results of reactive HIV in 12 donor blood (0,08%). non-reactive blood donor of HIV  in age groups 18 years, 18-24, 25-44, 45-59, and ≥ 60 years respectively 9,55%, 22,39%, 51,75%, 16,01% and 0,21%. Reactive HIV in age groups 18-24, 25-44, and 45-59 years were 0,034%, 0,034%, and 0,13%. Non-reactive HIV in men 68,22% and in women 31,70%. Reactive HIV in men 0,07%, and women 0,01%. Non-reactive HIV in voluntary donor blood was 99,779% and substitute donor was 0,127%. HIV of reactive voluntary donor blood was 0,074%, and substitute donor was 0,007%. HIV filter test is indispensable for blood safety because the age, gender and blood type of donors have the potential for reactive HIV.


1995 ◽  
Vol 14 (2) ◽  
pp. 221-228
Author(s):  
Carolyn R. Thompson

Despite a dramatic decline in transfusion-associated AIDS, increased safety of the national blood supply, and voluntary efforts to find alternatives to homologous blood sources, Americans remain fearful about the possibility of acquiring AIDS through a blood transfusion. Numerous states have initiated legislative efforts that would require explicit warnings about blood safety and that would direct patients to alternative sources of blood. These proposed laws—known as MANTRA bills, for “mandatory notification of transfusion alternatives”—would require physicians to advise patients of blood transfusion options prior to any surgery. Many would mandate the development of new informed consent documents and involve health departments in the implementation of new regulations regarding transfusions. This article concludes that MANTRA legislation is primarily a symbolic attempt to reassure the public about AIDS. It mandates practices that are being adopted voluntarily; it will not make the blood supply safer; it will increase the cost of health care to individuals and in the aggregate; it may diminish the number of donors to the voluntary blood supply system; and it is likely to intensify public fear about the risk of a blood transfusion.


2020 ◽  
Vol 8 ◽  
pp. 205031212093693
Author(s):  
Seblewongel Tsehay ◽  
Fatuma Hassen ◽  
Agete Tadewos Hirigo ◽  
Zinegnaw Abiy ◽  
Kassu Desta

Background: Blood transfusion is an intervention used to save life particularly for those patients who survive only with receiving blood. Establishing effective diagnostic test menus concerning the screening of transfusion-transmissible infections in the blood banks play a vital role to safeguard recipients from transfusion-transmissible infections. Objective: The aim of this study was to assess blood transfusion-transmissible malaria and its screening cost analysis in Hawassa regional blood bank, Hawassa, Sothern Ethiopia. Methods: An institutional-based cross-sectional study was conducted from April to May 2018 among 414 voluntary blood donors. Each participant’s blood sample was screened for most transfusion-transmissible infections using antigen/antibody tests, while rapid diagnostic test and microscopy were used for malaria screening and confirmation. In addition, the cost screening of transfusion-transmissible infections was calculated using activity-based costing method. Results: The overall seropositivity of transfusion-transmissible infections was 7.0% and the positivity rate of hepatitis B virus, syphilis, and Plasmodium falciparum was 5.6%, 1.0%, and 0.5%, respectively. The cost per test of each transfusion-transmissible infection was US$5.04 for human immunodeficiency virus, US$4.61 for hepatitis B virus, US$5.11 for hepatitis C virus, and US$4.75 for syphilis, while the cost per test of malaria rapid diagnostic test was US$4.74 and this is comparatively lower than the cost per test of other transfusion-transmissible infections except for hepatitis B virus. In addition, total cost of laboratory incurred for transfusion-transmissible infections screening is estimated to be US$213,634.5 per year, while it becomes US$265,537.5 if the malaria screening cost is added. This means 19.54% of the total cost of laboratory incurred per year or US$51,903. Conclusion: The positivity rate of malaria parasites among voluntary blood donors was 0.5%, and it might be increased if the study was conducted in high transmission seasons. A cost of malaria screening is comparatively lower than costs of other transfusion-transmissible infections except for hepatitis B virus. Therefore, the screening of malaria parasites should be considered as one of the test menus of transfusion-transmissible infections in blood banks, especially in malaria-endemic areas.


Author(s):  
Chris Cooper

‘Blood transfusion’ outlines the history of transfusing animal blood dating back to the 17th century. The 19th century saw the first successful human blood transfusion, but two major issues remained: the problems of clotting and blood group incompatibility. Albert Hustin and Luis Agote resolved the first issue in 1914 by using sodium citrate in transfusions to work as an anticoagulant. Richard Lewisohn calculated the correct levels of citrate needed to avoid poisoning the blood. Karl Landsteiner’s work in early 20th-century Vienna revealed the ABO blood type distinctions, solving the latter problem. The creation of blood banks and the potential for viral contamination of blood and blood products are also discussed.


1972 ◽  
Vol 71 (S1) ◽  
pp. s15-s34
Author(s):  
J. G. Watt ◽  
J. K. Smith ◽  
W. Grant ◽  
C. Turnbull

‘Selective transfusion of appropriate blood components is preferable to the routine use of whole blood.’ (American Association of Blood Banks. Physicians' Handbook of Blood Component Therapy, 1969).The rational use of donor blood in the environment of modern blood transfusion revolves around a series of developments in the field of component therapy. The fractionation of plasma, i.e. the separation of plasma into a series of subdivisions each containing one or other of the constituent proteins in varying degrees of purity and concentration, was one of the first of these developments to become established.Early fractionation of plasma was applied in various ways to the purification of animal antisera; initially to antipneumococcal serum for therapeutic use. These sera frequently provoked reactions in patients until Sabin showed that absorption with Fullers earth could abolish these side-effects by removing complexed molecules.


Author(s):  
Christian Mangala ◽  
Joseph Fokam ◽  
Denis Maulot Bangola ◽  
Thérèse Nkoa

Background: The genetic diversity of human immunodeficiency virus type 1 (HIV-1) is a real problem facing blood banks. This genetic diversity has a negative impact on diagnostic strategies within the transfusion chain by weakening the security of the donation. The objective of this study is to clarify the concepts emanating from the research project entitled : «Genetic diversity of HIV-1 and its effect on the residual risk in blood transfusion in Gabon». Methods: This study was the result of a systematic review and a conceptual analysis of several studies that were systematically searched for in databases (PubMed, Google Scholar, and Medline), and whose object was focused on the genetic diversity of HIV -1 and its impact on transfusion safety. Indeed, the information relating to the concepts coming from the full articles was used. These were obtained by reading the most relevant articles. All relevant studies reporting data on HIV-1 genetic diversity and blood safety published in English between January 2012 and December 2020 have been identified for context. The method of conceptual analysis of « Walker and Avant (2005) » was used to clarify the different concepts of our study. The correlation test was used to show the relationship between the concepts. Results: This systematic review and conceptual analysis study made it possible to determine the variables and to clarify the different concepts (HIV-1, Genetic diversity, Blood transfusion, Residual risk) essential for carrying out our research project entitled: "Genetic diversity of HIV-1 and its effect on the residual risk in blood transfusion". This model made it possible to show the effect of the genetic diversity of HIV-1 on the residual risk in blood transfusion using as model variables : viral load and serological markers (Antibodies and P24 Antigen). Knowledge of molecular strains (URF, CRF, subtypes) during this study made it possible to better identify the molecular strains most involved in the residual risk. Despite its complexity, this conceptual analysis contributed enormously to the understanding of the activities and the quantifiable and non-quantifiable components that participated in our study. Statistical analysis showed that the HIV-1 concept was significantly related to the other three concepts with P = 0.001. Likewise for the concept of genetic diversity was also significantly linked to the two other concepts with P = 0.003. Conclusion: The genetic diversity of HIV-1 in the blood transfusion environment contributes significantly to the transmission of HIV from donor to recipient. The mastery of these molecular strains is essential for the various blood banks to ensure a safe blood supply.


2014 ◽  
Vol 19 (14) ◽  
Author(s):  
D Musso ◽  
T Nhan ◽  
E Robin ◽  
C Roche ◽  
D Bierlaire ◽  
...  

Since October 2013, French Polynesia has experienced the largest documented outbreak of Zika virus (ZIKAV) infection. To prevent transmission of ZIKAV by blood transfusion, specific nucleic acid testing of blood donors was implemented. From November 2013 to February 2014: 42 (3%) of 1,505 blood donors, although asymptomatic at the time of blood donation, were found positive for ZIKAV by PCR. Our results serve to alert blood safety authorities about the risk of post-transfusion Zika fever.


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