lead, cadmium and zinc in infertile women compared to fertile women

2006 ◽  
Vol 14 (1) ◽  
pp. 59-71
Author(s):  
Soad Mosad ◽  
Hesham. Shalaan
Keyword(s):  
Infertile Women ◽  
Fertile Women

scholarly journals A Two-Cohort RNA-seq Study Reveals Changes in Endometrial and Blood miRNome in Fertile and Infertile Women

Genes ◽  
2018 ◽  
Vol 9 (12) ◽  
pp. 574 ◽  
Author(s):  
Kadri Rekker ◽  
Signe Altmäe ◽  
Marina Suhorutshenko ◽  
Maire Peters ◽  
Juan F. Martinez-Blanch ◽  
...  
Keyword(s):  
Embryo Implantation ◽  
Endometrial Receptivity ◽  
Small Rna Sequencing ◽  
Rna Seq ◽  
Recurrent Implantation Failure ◽  
Secretory Phase ◽  
Blood Samples ◽  
Infertile Women ◽  
Secretory Endometrium ◽  
Fertile Women

The endometrium undergoes extensive changes to prepare for embryo implantation and microRNAs (miRNAs) have been described as playing a significant role in the regulation of endometrial receptivity. However, there is no consensus about the miRNAs involved in mid-secretory endometrial functions. We analysed the complete endometrial miRNome from early secretory (pre-receptive) and mid-secretory (receptive) phases from fertile women and from patients with recurrent implantation failure (RIF) to reveal differentially expressed (DE) miRNAs in the mid-secretory endometrium. Furthermore, we investigated whether the overall changes during early to mid-secretory phase transition and with RIF condition could be reflected in blood miRNA profiles. In total, 116 endometrial and 114 matched blood samples collected from two different population cohorts were subjected to small RNA sequencing. Among fertile women, 91 DE miRNAs were identified in the mid-secretory vs. early secretory endometrium, while no differences were found in the corresponding blood samples. The comparison of mid-secretory phase samples between fertile and infertile women revealed 21 DE miRNAs from the endometrium and one from blood samples. Among discovered novel miRNAs, chr2_4401 was validated and showed up-regulation in the mid-secretory endometrium. Besides novel findings, we confirmed the involvement of miR-30 and miR-200 family members in mid-secretory endometrial functions.

scholarly journals Comparison of ovarian stromal blood flow between fertile women with normal ovaries and infertile women with polycystic ovary syndrome

2005 ◽  
Vol 20 (7) ◽  
pp. 1881-1886 ◽  
Author(s):  
Ernest Hung Yu Ng ◽  
Carina Chi Wai Chan ◽  
William Shu Biu Yeung ◽  
Pak Chung Ho
Keyword(s):  
Blood Flow ◽  
Polycystic Ovary Syndrome ◽  
Polycystic Ovary ◽  
Ovary Syndrome ◽  
Infertile Women ◽  
Fertile Women

scholarly journals Depression Severity and Sexual Satisfaction in Fertile and Infertile Women in Iran: A Population-Based Case-Control Study

2021 ◽  
Vol In Press (In Press) ◽  
Author(s):  
Katayoun Bakhtiar ◽  
Arash Ardalan ◽  
Farzad Ebrahimzadeh ◽  
Mohammad Almasian ◽  
Fatemeh Bastami
Keyword(s):  
Sexual Satisfaction ◽  
Case Control Study ◽  
Case Control ◽  
Marginal Model ◽  
Depression Severity ◽  
Infertile Women ◽  
Sexual Dissatisfaction ◽  
Confounding Variables ◽  
Control Study ◽  
Fertile Women

Background: Depression and sexual dissatisfaction are among the most common psychological factors caused by infertility. Infertility is an essential topic in the Iranian culture, and many studies have already investigated it. Objectives: This study aimed to compare the depression severity and sexual dissatisfaction between fertile and infertile women in Iran. Methods: This case-control study enrolled 180 infertile women and 540 fertile women in 2019. The participants were selected through multistage stratified and cluster sampling methods. For each infertile woman, three fertile women were randomly selected. The data collection instruments consisted of a demographic form, the Depression Inventory Scale (Second Edition), and the Linda Berg Sexual Satisfaction Questionnaire. The multivariate marginal model and SPSS version 21 were used for data analysis at a significance level of 0.05. Results: After adjustment for confounding variables, the marginal model showed that the odds of depression increased by approximately 21.305 times among cases compared to controls (OR = 21.305, 95% CI = 14.75 - 32.021, P < 0.001). This model also found that by moderating the effects of confounding variables, infertility increased the odds of low sexual satisfaction by approximately 15.560 times (OR = 15.560, 95% CI = 5.089 - 47.571, P < 0.001). The chi-square test showed a significant relationship between infertility treatment and depression severity in infertile women (P = 0.001). Conclusions: The overall depression severity and sexual dissatisfaction were higher in the infertile group than in the fertile one. Most cases of severe depression were observed in IVF clinics with higher depression levels. The study may help reveal infertility's psychological and social aspects in Iran.

scholarly journals Examination of sexual functions and depressive symptoms among infertile and fertile women

2019 ◽  
Vol 35 (5) ◽  
Author(s):  
Selda Ozturk ◽  
Hatice Kahyaoglu Sut ◽  
Leyla Kucuk
Keyword(s):  
Depressive Symptoms ◽  
Sexual Dysfunction ◽  
Sexual Function ◽  
Sexual Intercourse ◽  
Beck Depression Inventory ◽  
Female Sexual Function ◽  
Cross Sectional ◽  
Infertile Women ◽  
Significant Difference ◽  
Fertile Women

Objective: To examine the sexual functions and depressive symptoms of infertile and fertile women. Methods: This study was conducted between October 2015 and April 2016 using a descriptive, cross-sectional and comparative design. The sample of this study consisted of 96 infertile and 96 fertile women. The data were collected using an information form, the Beck Depression Inventory and the Index of Female Sexual Function. The data were analyzed The Mann-Whitney U test, chi-square test, and Spearman’s correlation analysis. Results: The rate of sexual dysfunction (87.5% vs. 69.8%) and the Index of Female Sexual Function total score (31.8 ± 7.8 vs 35.7 ± 6.3) were significantly higher in infertile women than fertile women (p=0.003, p<0.001, respectively). The sexual satisfaction and discomfort during sexual intercourse subscales of the Index of Female Sexual Function were significantly lower among infertile women than fertile women (p<0.001 for all); however, no significant difference was observed in the sexual intercourse/libido score of the Index of Female Sexual Function between infertile and fertile women (p=0.590). The correlation coefficients between the Beck Depression Inventory total score and the total and subscale scores of the IFSF did not significantly differ between infertile and fertile women (p>0.05 for all). Conclusion: The sexual dysfunction rate among infertile women was higher than that among fertile women. Sexual functions decreased when depressive symptoms increased for both infertile and fertile women. doi: https://doi.org/10.12669/pjms.35.5.615 How to cite this:Ozturk S, Sut HK, Kucuk L. Examination of sexual functions and depressive symptoms among infertile and fertile women. Pak J Med Sci. 2019;35(5):---------. doi: https://doi.org/10.12669/pjms.35.5.615 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

The comparison of mental health in fertile and infertile women

2011 ◽  
Vol 26 (S2) ◽  
pp. 1666-1666 ◽  
Author(s):  
H. Jamilian ◽  
M. Jamilian ◽  
F. Doroodgar Hezaveh
Keyword(s):  
Mental Health ◽  
Case Control Study ◽  
Somatic Complaints ◽  
Control Group ◽  
Case Group ◽  
Family Function ◽  
Infertile Women ◽  
Mental Disturbances ◽  
Control Study ◽  
Fertile Women

IntroductionInfertility affects life of couples and family function. Infertility can cause mental disturbances in some studies.AimsThe goal of this study was the comparison of mental health in fertile and infertile women.MethodsA case-control study was done in Arak-Iran, Taleghani hospital which is a center of Gynecology, in 2010. 60 infertile women as case group and 60 fertile women as control group participated in the study, randomly. Both groups were assessed by GHQ questionnaire and data were analyzed by T-Test and logistic regression.ResultsThe severity of mental disturbances were much more in infertile women (P < 0.001). Social dysfunction (P < 0.001) and somatic complaints (P < 0.001) were also higher in infertile women. The probability of mental disturbances was much higher in infertile women (P < 0.001 and OR = 5.57).ConclusionMental health of infertile women is very critical and disturbed. The findings of our study necessitate the multidimensional interventions in the treatment of infertility.

scholarly journals Relationship of serum fasting insulin with gonadotropins in infertile women

2014 ◽  
Vol 29 (1-2) ◽  
pp. 17-24
Author(s):  
Shamima Bari ◽  
Rokeya Begum ◽  
Qazi Shamima Akter ◽  
Tanvir Alam ◽  
Kadeja Begum
Keyword(s):  
Blood Glucose ◽  
Serum Insulin ◽  
Fasting Blood Glucose ◽  
Insulin Level ◽  
Fasting Insulin ◽  
Serum Insulin Level ◽  
Fasting Serum ◽  
Infertile Women ◽  
Group B ◽  
Fertile Women

Background: Infertility has become a global health problem in the world wide affecting 8-10% of couple. It is also a matter of social injustice and inequality. Increase level of insulin has been implicated as a cause of infertility. Objective: To find out the association of fasting serum insulin level with gonadotropins in infertile women. Methods: This cross sectional study was conducted in the department of Physiology, Dhaka Medical College, Dhaka from July 2010 to June 2011. A total number of 150 female age ranged from 20 – 40 years were included in this study. Out of them100 infertile women were selected as study group (group B). Group B was subdivided into group B1 and B2. Group B1 consisted of 50 primary infertile women and group B2 consisted of 50 secondary infertile women. Rest 50 age matched apparently healthy parous women were considered as base line control group A. All the study subjects were selected from out patient department of infertility unit, BSMMU, Dhaka. The control subjects were selected by personal contact. Serum fasting insulin was measured by enzyme-link-immunosorbend assay. Fasting blood glucose and blood glucose two hours after breakfast were measured by glucose oxidase method. The Data were collected in a prescribed data sheet after taking written consent. Statistical analyses were done by unpaired students “t” tests by SPSS program version 12. The level of significance was calculated and p value <0.05 was accepted as level of significance. Results: In this study, the mean fasting serum insulin level were significantly higher in infertile women than those of fertile women (p<0.001). Within the study group serum fasting insulin was higher in primary infertile women than that of secondary infertile women both were statistically not significant. Again, serum FSH and LH levels were significantly lower (P<.0001) in infertile women than those of fertile women. But serum FSH level was lower and LH level was higher in primary infertile women than that of secondary infertile women. In addition, fasting blood glucose level was almost similar but within normal limits in all groups. Blood glucose 2HABF was significantly higher in secondary infertile women than that of fertile women but within in normal limit. Moreover, fasting serum insulin level was negatively correlated with serum FSH and LH in primary infertility but negatively correlated with serum FSH and positive correlation with serum LH in secondary infertility. Conclusion: From the above study it may be concluded that fasting serum insulin level was higher in infertile women than those of healthy fertile women. These alterations may lead to menstrual irregularities, ovulatory dysfunction and infertility. http://dx.doi.org/10.3329/bjpp.v29i1-2.20063 Bangladesh J Physiol Pharmacol 2013; 29(1&2) : 17-24

scholarly journals Polymorphism study of MTHFR 677C?T and its correlation with oxidative stress and their influence on female infertility in Erbil – Iraq

2017 ◽  
Vol 14 (3) ◽  
pp. 611-618
Author(s):  
Baghdad Science Journal
Keyword(s):  
Oxidative Stress ◽  
Methylenetetrahydrofolate Reductase ◽  
Group Living ◽  
Thyroid Stimulating Hormone ◽  
Female Infertility ◽  
Control Group ◽  
Sod Activity ◽  
Infertile Women ◽  
Fertile Women ◽  
Prolactin Hormone

This research includes a study of Methylenetetrahydrofolate reductase gene’s allele 677C?T and its correlation with oxidative stress and their impact on female infertility. Fifty infertile women with the range age (23-42) years and twenty five fertile women with the range age (22-39) years as control group living in Erbil city were selected. The serum level of Malondialdehyde (MDA), superoxide dismutase (SOD), prolactin hormone (PRL), Luteinizing hormone (LH), Thyroid stimulating hormone (TSH), Triiodothyronine hormone (T3), and Thyroxine hormone (T4) were measured, also a body mass index (BMI) was calculated. A restriction enzyme (Hinf1) was used to improve the mutation in DNA bands of infertile women. The results showed significant increases in MDA level, SOD activity, BMI, PRL, LH, TSH, and T4 in patients women compared with the control group. The results show non-significant differences in T3 hormone levels. The results also show a mutation in DNA bands of infertile women compared with fertile control group.

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