scholarly journals Impact of Obesity, Visceral Adiposity and Metabolic Syndrome on Male Fertility

2021 ◽  
pp. 1-8
Author(s):  
Esra Bahar GUR ◽  
Ebru Sahin GULEC ◽  
Sadik INCE ◽  
Mehmet Zeynel KESKIN ◽  
Ahmet DEMIR ◽  
...  
Keyword(s):  
Metabolic Syndrome ◽  
Body Mass Index ◽  
Regression Analysis ◽  
Visceral Fat ◽  
Male Fertility ◽  
Sperm Morphology ◽  
Anthropometric Measurements ◽  
Semen Parameters ◽  
Anthropometric Indexes ◽  
Fat Thickness

OBJECTIVE: The study aimed to assess the association between the separate anthropometric indexes including visceral adiposity and metabolic syndrome on male fertility. STUDY DESIGN: In a cross-sectional study, the visceral and subcutaneous fat thickness of 162 participants were measured by ultrasonography. Participants' body mass index, waist circumference, and waist/hip ratio were determined. Participants' biochemical metabolic parameters and reproductive hormones were measured and semen parameters were recorded. Participants were divided into groups according to body mass index and different percentiles of the visceral fat thickness. Differences between groups were investigated by One-way ANOVA, Kruskal-Wallis H, and Pearson Chi-Square test. The relationship between anthropometric measurements and sperm parameters was evaluated by Pearson and Spearman’s rank correlation test. The effect of anthropometric indexes on sperm parameters was evaluated using multivariate regression analysis. RESULTS: It was seen that only total testosterone of sex hormones decreased significantly in the obesity group (p=0.003). There was a significant and reverse association between visceral fat thickness with sperm morphology (rho=–0.2, p=0.01). There was no significant correlation between semen parameters and other anthropometric measurements. In multiple regression analysis, the effect of anthropometric measurements, including visceral fat thickness, on semen parameters was not found, but only smoking was found to be a factor affecting sperm concentration, progressive motility, and morphology (p=0.03, p=0.03, and p=0.01). CONCLUSION: In this study, it was shown that increased obesity was associated with low testosterone levels and increased visceral fat was associated with abnormal sperm morphology. More extensive studies are required on this subject.

scholarly journals Pancreatic Fat Is Associated With Metabolic Syndrome and Visceral Fat but Not Beta-Cell Function or Body Mass Index in Pediatric Obesity

Pancreas ◽  
2017 ◽  
Vol 46 (3) ◽  
pp. 358-365 ◽  
Author(s):  
Johan Staaf ◽  
Viktor Labmayr ◽  
Katharina Paulmichl ◽  
Hannes Manell ◽  
Jing Cen ◽  
...  
Keyword(s):  
Metabolic Syndrome ◽  
Body Mass Index ◽  
Beta Cell ◽  
Body Mass ◽  
Visceral Fat ◽  
Pediatric Obesity ◽  
Beta Cell Function ◽  
Cell Function ◽  
Pancreatic Fat

scholarly journals Metabolic Syndrome and Reproduction

2021 ◽  
Vol 22 (4) ◽  
pp. 1988
Author(s):  
Francesco Lotti ◽  
Sara Marchiani ◽  
Giovanni Corona ◽  
Mario Maggi
Keyword(s):  
Metabolic Syndrome ◽  
Male Fertility ◽  
English Language ◽  
Negative Impact ◽  
Reproductive Potential ◽  
Underlying Mechanism ◽  
Semen Parameters ◽  
Preclinical Studies ◽  
Medline Search ◽  
High Prevalence

Metabolic syndrome (MetS) and infertility are two afflictions with a high prevalence in the general population. MetS is a global health problem increasing worldwide, while infertility affects up to 12% of men. Despite the high prevalence of these conditions, the possible impact of MetS on male fertility has been investigated by a few authors only in the last decade. In addition, underlying mechanism(s) connecting the two conditions have been investigated in few preclinical studies. The aim of this review is to summarize and critically discuss available clinical and preclinical studies on the role of MetS (and its treatment) in male fertility. An extensive Medline search was performed identifying studies in the English language. While several studies support an association between MetS and hypogonadism, contrasting results have been reported on the relationship between MetS and semen parameters/male infertility, and the available studies considered heterogeneous MetS definitions and populations. So far, only two meta-analyses in clinical and preclinical studies, respectively, evaluated this topic, reporting a negative association between MetS and sperm parameters, testosterone and FSH levels, advocating, however, larger prospective investigations. In conclusion, a possible negative impact of MetS on male reproductive potential was reported; however, larger studies are needed.

P5301Impacts of lifestyle behavior and shift Work on visceral fat accumulation and progression of atherosclerosis in middle-aged workers

2019 ◽  
Vol 40 (Supplement_1) ◽  
Author(s):  
T Sugiura ◽  
Y Dohi ◽  
N Yoshikane ◽  
M Ito ◽  
K Suzuki ◽  
...  
Keyword(s):  
Metabolic Syndrome ◽  
Logistic Regression ◽  
Regression Analysis ◽  
Shift Work ◽  
Visceral Fat ◽  
Regular Exercise ◽  
Shift Workers ◽  
Visceral Fat Accumulation ◽  
Habitual Smoking ◽  
Progression Of Atherosclerosis

Abstract Background Work style, and particularly shift work, can affect an individual's health through disrupting circadian rhythms. Moreover, lifestyle habits including dietary and exercise routines might be altered by irregular shift hours. We thus hypothesized that an individual's lifestyle including working habits could influence the prevalence of visceral fat obesity and the progression of atherosclerosis. Purpose The present study investigated how lifestyle and shift work affect the accumulation of visceral fat and the progression of subclinical atherosclerosis in middle-aged workers. Methods This study enrolled employees undergoing their periodic health check-up (n=10883). The Cardio-Ankle Vascular Index (CAVI) was measured to assess arterial stiffness, followed by ultrasound examination and computed tomography imaging to measure carotid intima-media thickness (IMT) and visceral fat area (VFA), respectively. Lifestyle was evaluated by the following items: 1) eating breakfast, 2) nighttime eating, 3) regular exercise, 4) habitual drinking, 5) habitual smoking, 6) sleeping hours, and 7) working hours. With regard to work factors, subjects were categorized into fixed daytime workers or shift workers (including subjects working with an irregular schedule, outside of daytime hours, or at nighttime). Results Among all subjects enrolled, 6820 subjects were fixed daytime workers and 4063 subjects were shift workers. Most of the employees engaged in fixed daytime work were clerical workers, while the employees engaged in shift work were mainly physical workers in this company. Fixed daytime workers had significantly greater VFA than shift workers, but the prevalence of metabolic syndrome, CAVI values, and carotid IMT were similar between groups. Reduced regular exercise, long sleeping hours, and fixed daytime work were independently associated with visceral fat accumulation by both multivariate regression and logistic regression analyses. However, the logistic regression analysis with the presence of metabolic syndrome as the endpoint revealed that skipping breakfast, reduced regular exercise, long sleeping hours, and short working hours were independent determinants of metabolic syndrome. On the other hand, univariate and multivariate regression analysis showed that habitual smoking, but not shift work, were significantly associated with CAVI and carotid IMT. Logistic regression analysis with the endpoint of carotid atherosclerosis (presence of plaque) showed that habitual smoking was an independent determinant of carotid atherosclerosis. Conclusions Reduced regular exercise, long sleeping hours, and fixed daytime work were significantly associated with visceral fat accumulation, while habitual smoking has a consistent association with the progression of atherosclerosis. These findings support the concept that unhealthy lifestyles should be modified before considering intervention in work styles.

Ultrasonographic visceral fat thickness in the first trimester can predict metabolic syndrome and gestational diabetes mellitus

Endocrine ◽  
2014 ◽  
Vol 47 (2) ◽  
pp. 478-484 ◽  
Author(s):  
Esra Bahar Gur ◽  
Ozlem Ince ◽  
Guluzar Arzu Turan ◽  
Muammer Karadeniz ◽  
Sumeyra Tatar ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Metabolic Syndrome ◽  
Gestational Diabetes ◽  
Gestational Diabetes Mellitus ◽  
Visceral Fat ◽  
First Trimester ◽  
Fat Thickness

scholarly journals Evaluation of anthropometric indices as metabolic syndrome predictors in Ecuadorian Military Personnel

2020 ◽  
Vol 41 (2) ◽  
pp. 141-147
Author(s):  
Germán Muñoz ◽  
Alberth Patricio Muñoz Gualan
Keyword(s):  
Metabolic Syndrome ◽  
Body Mass Index ◽  
Military Personnel ◽  
Operating Characteristic ◽  
Area Under The Curve ◽  
Anthropometric Measurements ◽  
Height Ratio ◽  
Anthropometric Indices ◽  
Low Prevalence ◽  
Waist Height Ratio

Anthropometric measurements are simple and effective techniques for central or abdominal obesity evaluation. Although it is known their good predicting value, there is not a consensus about which is best in Metabolic Syndrome (MetSyn) diagnostic, using ATP III criteria. Anthropometric measurements included waist circumference (WC), waist hip ratio (WHR), waist height ratio (WHtR) and body mass index (BMI). This study aimed to determine the prevalence of MetSyn and compare anthropometric indices for optimal predicting value with their respective cut-offs for MetSyn diagnosis among army members in ESFORSE, Ecuador. The study includes 181 participants (175 male and 6 female), with mean age 37 ± 6 years, MetSyn prevalence is 8%, with WC (p <.001), WHtR (p. .009) and WHR (p .020) as variables statistically significant. We analyzed the area under the curve (AUC) in a receiver operating characteristic (ROC) curve, in anthropometric measurements. Thus, WC and WHtR represent the highest AUC (WC: 0.77, 95% CI 0.69-0.86; WHtR: 0.70, 95% CI 0.59-0.82). The optimal cut-off values for predicting MetSyn are 92 cm in WC, 0.52 in WHtR and 0.93 in WHR. Therefore, the army members have a low prevalence of MetSyn, with WC as the best predicting value.

scholarly journals Prevalence of Hypogonadism in a Male Population below 60 Years of Age with Metabolic Syndrome

2015 ◽  
Vol 2015 ◽  
pp. 1-7
Author(s):  
Rafael Ríos ◽  
Natalia Jara ◽  
Bernardita Ratkman ◽  
Alejandra Valenzuela ◽  
Carla Palavecino ◽  
...  
Keyword(s):  
Insulin Resistance ◽  
Metabolic Syndrome ◽  
Regression Analysis ◽  
Visceral Fat ◽  
Linear Regression Analysis ◽  
Free Testosterone ◽  
Homa Index ◽  
Male Population ◽  
Insulin Resistant ◽  
High Prevalence

Introduction. A high prevalence of hypogonadism (H) has been demonstrated in patients with metabolic syndrome (MetS). There are no studies in Latin America showing the prevalence of H in MetS in men below 60 years of age. The objective of this study was to determine the association between the MetS and levels of testosterone (T) and calculated free testosterone (cfT) in men under 60 years of age. Methodology. 101 men were included between 18 and 60 years who met the IDF MetS criteria. The diagnosis of H was considered <70 pg/mL of cfT and <10.4 nmol/L (300 ng/dL) of T. Results. H with T was 17.8% and 20.7% with cfT. The H according to T had higher BMI, waist circumference, visceral fat, markers of insulin resistance, SHBG, LH, and E2. We find an inverse but weak significant correlation between T, visceral fat, and HOMA index. The linear regression analysis showed that E2 and visceral fat are determinants in H. Conclusion. We found a high prevalence of H using T and cfT in Chilean patients with MetS below 60 years of age, who turned out to be more insulin-resistant and have more visceral fat, waist, and E2 than non-H.

scholarly journals Potential Role of New Anthropometric Parameters in Childhood Obesity with or Without Metabolic Syndrome

2019 ◽  
Vol 7 (23) ◽  
pp. 3930-3936 ◽  
Author(s):  
Nagwa Abdallah Ismail ◽  
Shadia H. Ragab ◽  
Abeer M. Nour E lDin Abd ElBaky ◽  
Mona Hamid Ibrahim
Keyword(s):  
Metabolic Syndrome ◽  
Visceral Fat ◽  
Subcutaneous Fat ◽  
Shape Index ◽  
Visceral Adiposity Index ◽  
Obese Children ◽  
Anthropometric Parameters ◽  
Liver Size ◽  
Subcutaneous Fat Thickness ◽  
Fat Thickness

BACKGROUND: Obese children and adolescents are more prone to have metabolic syndrome (MS).MS is a cluster of cardiovascular risk factors associated with insulin resistance. Body round index [BRI], visceral adiposity index [VAI] and a body shape index [ABSI] are among the new obesity anthropometric parameters. AIM: To evaluate the new markers for obesity in children and their possible association with other laboratory and clinical variables of MS. METHODS: Eighty nine obese children and 40 controls aged 10-18 years were recruited. Full history taking, thorough clinical examination, anthropometric and biochemical features were performed in the studied groups. Subcutaneous fat thickness (SFT) and visceral fat thickness (VFT) were estimated by ultrasonography. RESULTS: Obese children, exhibited significantly higher values in all anthropometric measurements (P < 0.001). Diastolic and systolic blood pressure were significantly higher (P < 0.001) in the obese group. ABSI, BRI and VAI have been found to be significantly higher in obese subjects (P < 0.001), with no significant gender difference. BMI, WHtR, WC/HR, SBP, DBP, subcutaneous fat thickness and visceral fat thickness, Liver Span, ABSI, BRI, VAI and HOMA_IR were significantly higher among children with MS than those without MS. Positive significant correlations of VAI with BMI, WC/Ht, WC/Hip, SBP, DBP, SFT, VFT, Liver size and HOMA-IR (r = 0.384, 0.239, 0.268, 0.329, 0.516, 0.320, 0.254, 0.251, and 0.278 respectively) are shown. The area under the ROC curve (AUC) of BMI, VAI, ABSI, BRI for predicting MS was 0.802 (0.701-0.902), 0.737 (0.33-0.841), 0.737 (0.620-0.855), 0.816 (0.698-0.934). CONCLUSION: We suggest using the VAI and WHtR indexes, as they are better predictor of MS.

scholarly journals Identification of Cardiovascular Risk Factors in Obese Adolescents With Metabolic Syndrome

2021 ◽  
Vol 9 ◽  
Author(s):  
Jung Won Lee ◽  
Young Mi Hong ◽  
Hae Soon Kim
Keyword(s):  
Risk Factors ◽  
Cardiovascular Disease ◽  
Metabolic Syndrome ◽  
Body Mass Index ◽  
Left Ventricular Mass ◽  
Body Mass ◽  
Fat Mass ◽  
Left Ventricular ◽  
Obese Adolescents ◽  
Fat Thickness

Objective: There are studies that show different associations between metabolic syndrome (MS) and cardiovascular disease in adolescent. This study is aimed to identify probable cardio-vascular risk factors in obese adolescents with MS.Methods: Sixty-five obese adolescents with a body mass index (BMI) &gt; 95 percentile were enrolled and divided into two groups with MS or without MS. Left ventricular mass (LVM), left ventricular mass index, ejection fraction, epicardial fat thickness, visceral fat thickness (VFT) and carotid intima-media thickness were measured. Anthropometric and blood chemistry parameters were estimated. Above parameters were compared based on presence or absence of MS.Results: The prevalence of MS was 23.1% in obese adolescents. LVM showed significant correlation with body mass index (BMI), hip circumference (HC), fat mass, total cholesterol (TC), LDL-cholesterol (LDL-C) and waist circumference (WC). VFT significantly correlated with WC, BMI, hip circumflex (HC), obesity index (OI), fat %, fat mass, insulin, TC, LDL-C, insulin, triglyceride (TG), glucose, homeostatic model assessment for insulin resistance (HOMA-IR) and leptin.Conclusions: Screening for the MS in overweight adolescents may help to predict risk of future cardiovascular disease. These data suggest that LVMI and VFT are significant parameters for predicting cardiovascular disease risk in obese adolescents.

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