scholarly journals Distributing File-Based Data to Remote Sites Within the BABAR Collaboration

2002 ◽  
Author(s):  
Stephen J Gowdy
Keyword(s):  
Babar Collaboration ◽  
Remote Sites

Hepatocyte ultrastructural alterations in perimetastatic areas

1996 ◽  
Vol 54 ◽  
pp. 768-769
Author(s):  
H. J. Finol ◽  
M. E. Correa ◽  
L.A. Sosa ◽  
A. Márquez ◽  
N.L. Díaz
Keyword(s):  
Malignant Tumor ◽  
Malignant Tumors ◽  
Surrounding Tissue ◽  
Ultrastructural Changes ◽  
Pancreas Carcinoma ◽  
Duct Carcinoma ◽  
Tissue Samples ◽  
Primary Malignant Tumor ◽  
Transmission Electron ◽  
Remote Sites

In classical oncological literature two mechanisms for tissue aggression in patients with cancer have been described. The first is the progressive invasion, infiltration and destruction of tissues surrounding primary malignant tumor or their metastases; the other includes alterations produced in remote sites that are not directly affected by any focus of disease, the so called paraneoplastic phenomenon. The non-invaded tissue which surrounds a primary malignant tumor or its metastases has been usually considered a normal tissue . In this work we describe the ultrastructural changes observed in hepatocytes located next to metastases from diverse malignant tumors.Hepatic biopsies were obtained surgically in patients with different malignant tumors which metatastized in liver. Biopsies included tumor mass, the zone of macroscopic contact between the tumor and the surrounding tissue, and the tissue adjacent to the tumor but outside the macroscopic area of infiltration. The patients (n = 5), 36–75 years old, presented different tumors including rhabdomyosarcoma, leiomyosarcoma, pancreas carcinoma, biliar duct carcinoma and colon carcinoma. Tissue samples were processed with routine techniques for transmission electron microscopy and observed in a Hitachi H-500 electron microscope.

Opening New Worlds of Information: Library Technology and Internet Access for Patrons with Disabilities

2013 ◽  
Author(s):  
Courtney Deine-Jones
Keyword(s):  
Internet Access ◽  
The Internet ◽  
Electronic Information ◽  
On Line ◽  
Remote Sites ◽  
Technological Improvements ◽  
Library Technology

As more libraries offer patron access to the Internet and other on-line services, they must consider the needs of patrons with disabilities who will be using their Internet links either from the library or from remote sites. In planning and implementing technological improvements to optimize access for all patrons, librarians and information specialists must take into account questions of both physical and intellectual access to electronic information. This paper addresses these issues from a pragmatic perspective, reviewing available options and suggesting strategies for improving access for people with various disabilities.

scholarly journals Structural studies of phosphorylation-dependent interactions between the V2R receptor and arrestin-2

2021 ◽  
Vol 12 (1) ◽  
Author(s):  
Qing-Tao He ◽  
Peng Xiao ◽  
Shen-Ming Huang ◽  
Ying-Li Jia ◽  
Zhong-Liang Zhu ◽  
...  
Keyword(s):  
Crystal Structures ◽  
Conformational Changes ◽  
Nmr Spectrum ◽  
H Nmr ◽  
Interaction Sites ◽  
Receptor Interactions ◽  
Remote Sites ◽  
Genetic Code Expansion ◽  
G Protein Coupled ◽  
Interaction Change

AbstractArrestins recognize different receptor phosphorylation patterns and convert this information to selective arrestin functions to expand the functional diversity of the G protein-coupled receptor (GPCR) superfamilies. However, the principles governing arrestin-phospho-receptor interactions, as well as the contribution of each single phospho-interaction to selective arrestin structural and functional states, are undefined. Here, we determined the crystal structures of arrestin2 in complex with four different phosphopeptides derived from the vasopressin receptor-2 (V2R) C-tail. A comparison of these four crystal structures with previously solved Arrestin2 structures demonstrated that a single phospho-interaction change results in measurable conformational changes at remote sites in the complex. This conformational bias introduced by specific phosphorylation patterns was further inspected by FRET and 1H NMR spectrum analysis facilitated via genetic code expansion. Moreover, an interdependent phospho-binding mechanism of phospho-receptor-arrestin interactions between different phospho-interaction sites was unexpectedly revealed. Taken together, our results provide evidence showing that phospho-interaction changes at different arrestin sites can elicit changes in affinity and structural states at remote sites, which correlate with selective arrestin functions.

The First Very Broadband Mediterranean Network: 30 Yr of Data and Seismological Research

2019 ◽  
Vol 91 (2A) ◽  
pp. 787-802
Author(s):  
Silvia Pondrelli ◽  
Francesca Di Luccio ◽  
Laura Scognamiglio ◽  
Irene Molinari ◽  
Simone Salimbeni ◽  
...  
Keyword(s):  
Seismic Source ◽  
Global Scale ◽  
Anthropogenic Noise ◽  
Earth Structure ◽  
Backbone Network ◽  
Early Adoption ◽  
Stable Conditions ◽  
Remote Sites ◽  
The Mediterranean

Abstract Starting in 1988, with the installation of the first broadband (BB) instrument in Italy, the Mediterranean Very Broadband Seismographic Network (MedNet) program established a backbone network of BB stations of the highest quality in the Mediterranean Sea countries. The Mediterranean region is characterized by relevant and frequent seismicity related to its complex tectonics, due to the convergence of two major plates, Africa and Eurasia, and the involvement of other minor plates, as the Adriatic plate. Therefore, the MedNet project became a scientific research infrastructure of excellence, able to fill the gap of regional coverage when the availability of seismic BB instruments was still scarce. The main characteristics of the MedNet network are the highest quality of the seismographic instrumentation at remote sites and very low level of anthropogenic noise with stable conditions of pressure and temperature. After 30 yr of recordings, the MedNet program has proven that the early adoption of very BB instruments in selected sites have been the best choice. A large number of studies benefited from MedNet data, as seismic source computation and Earth structure reconstruction, at local and global scale. We present a concise overview of the contribution given by MedNet data in the last three decades to motivate and financially support the existence of this valuable infrastructure, and to further maintain this project.

scholarly journals RECENT τ LEPTON RESULTS FROM BABAR

2014 ◽  
Vol 35 ◽  
pp. 1460440
Author(s):  
ALBERTO LUSIANI
Keyword(s):  
Standard Model ◽  
Branching Fractions ◽  
Charged Particles ◽  
Babar Collaboration ◽  
Final States ◽  
Final State ◽  
Experimental Knowledge ◽  
Electron Positron ◽  
The Standard Model ◽  
Positron Collisions

We report recent measurements on τ leptons obtained by the BABAR collaboration using the entire recorded sample of electron-positron collisions at and around the Υ(4S) (about 470fb-1). The events were recorded at the PEP-II asymmetric collider at the SLAC National Accelerator Laboratory. The measurements include high multiplicity τ decay branching fractions with 3 or 5 charged particles in the final state, a search for the second class current the τ decay τ → πη′ν, τ branching fractions into final states containing two KS mesons, [Formula: see text], with h = π, K, and preliminary measurements of hadronic spectra of τ decays with three hadrons (τ- → h-h+h-ντ decays, where h = π, K). The results improve the experimental knowledge of the τ lepton properties and can be used to improve the precision tests of the Standard Model.

Interactive Television: Delivering Quality Graduate Nursing Education to Remote Sites

1994 ◽  
Vol 33 (4) ◽  
pp. 188-190
Author(s):  
Barbara Kooler Kooker ◽  
Joanne Itano ◽  
Joan Efinger ◽  
Joyce Dungan ◽  
Marilyn Majoc
Keyword(s):  
Nursing Education ◽  
Interactive Television ◽  
Remote Sites ◽  
Graduate Nursing

Problem crocodiles, Crocodylus porosus, at Nhulunbuy, Northern Territory: an assessment of relocation as a mangaement strategy

1993 ◽  
Vol 20 (1) ◽  
pp. 127 ◽  
Author(s):  
B Walsh ◽  
PJ Whitehead
Keyword(s):  
Carrying Capacity ◽  
Northern Territory ◽  
Effective Strategy ◽  
Wet Season ◽  
Rates Of Return ◽  
Saltwater Crocodile ◽  
Crocodylus Porosus ◽  
Remote Sites ◽  
Total Capture ◽  
Capture Rates

Since 1986 the Conservation Commission of the Northern Territory has operated a programme to remove 'problem' saltwater crocodiles from waters in and adjoining the township of Nhulunbuy. Over a period of five years, 52 different saltwater crocodiles (44 male) were captured. Most (48) were released at remote sites designated by the traditional Aboriginal owners of the surrounding lands. Release distances from the township varied from 17 to 282 km (by coastline). Many crocodiles (47.9%), including those released at the most distant sites, returned to, and were subsequently recaptured at, the township. Total capture rates (initial captures and recaptures pooled) varied seasonally, with fewer crocodiles being caught in the cooler dry season. During the wet season capture rates remained high, but relatively fewer 'new' crocodiles were caught. Probability of recapture could not be related to distance and direction of release from the township, nor size and sex of the released crocodile. Frequency of capture of individual crocodiles (1-8 times) was also unrelated to these variables. The high rates of return indicate that relocation is unlikely to be an effective strategy for managing humancrocodile interactions, at least in areas where potential release sites already support saltwater crocodile populations near carrying capacity.

scholarly journals Binding of Distinct Substrate Conformations Enables Hydroxylation of Remote Sites in Thaxtomin D by Cytochrome P450 TxtC

2018 ◽  
Vol 141 (1) ◽  
pp. 216-222 ◽  
Author(s):  
Lona M. Alkhalaf ◽  
Sarah M. Barry ◽  
Dean Rea ◽  
Angelo Gallo ◽  
Daniel Griffiths ◽  
...  
Keyword(s):  
Cytochrome P450 ◽  
Remote Sites

scholarly journals Technical innovations and optimizations for intermediate ice-core drilling operations

2014 ◽  
Vol 55 (68) ◽  
pp. 243-252 ◽  
Author(s):  
Jack Triest ◽  
Robert Mulvaney ◽  
Olivier Alemany
Keyword(s):  
Ice Core ◽  
Working Environment ◽  
Column Height ◽  
Drill Fluid ◽  
Drilling Operations ◽  
Remote Sites ◽  
James Ross Island ◽  
Technical Innovations ◽  
Set Up ◽  
Core Storage

AbstractThe British Antarctic Survey, in collaboration with Laboratoire de Glaciologie et Géophysique de l’Environnement, has in recent years successfully drilled to bedrock on three remote sites around the Antarctic Peninsula. Based on the experience from the multi-season project at Berkner Island (948m depth, 2002–05) we optimized the drill set-up to better suit two subsequent single-season projects at James Ross Island (363m depth, 2008) and Fletcher Promontory (654m depth, 2012). The adaptations, as well as the reasons for them, are discussed in detail and include a drill tent set-up without a trench; drilling without a borehole casing with a relatively low fluid column height; and using a shorter drill. These optimizations were aimed at reducing cargo loads and installation time while maintaining good core quality, productivity and a safe working environment. In addition, we introduce a number of innovations, ranging from a new lightweight cable tensioning device and drill-head design to core storage and protection trays. To minimize the environmental impact, all the drill fluid was successfully recovered at both sites and we describe and evaluate this operation.

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