scholarly journals Ultrasound and Microbubble Guided Drug Delivery: Mechanistic Understanding and Clinical Implications

2014 ◽  
Vol 14 (8) ◽  
pp. 743-752 ◽  
Author(s):  
Tzu-Yin Wang ◽  
Katheryne Wilson ◽  
Steven Machtaler ◽  
Jurgen Willmann
Keyword(s):  
Drug Delivery ◽  
Clinical Implications ◽  
Mechanistic Understanding

scholarly journals Clinical Implications of Exosomes: Targeted Drug Delivery for Cancer Treatment

2021 ◽  
Vol 22 (10) ◽  
pp. 5278
Author(s):  
Andrew E. Massey ◽  
Shabnam Malik ◽  
Mohammad Sikander ◽  
Kyle A. Doxtater ◽  
Manish K. Tripathi ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Tumor Microenvironment ◽  
Intercellular Communication ◽  
Targeted Drug Delivery ◽  
Clinical Implications ◽  
Disease States ◽  
Significant Research ◽  
The Common ◽  
Targeted Drug ◽  
Loading Methods

Exosomes are nanoscale vesicles generated by cells for intercellular communication. Due to their composition, significant research has been conducted to transform these particles into specific delivery systems for various disease states. In this review, we discuss the common isolation and loading methods of exosomes, some of the major roles of exosomes in the tumor microenvironment, as well as discuss recent applications of exosomes as drug delivery vessels and the resulting clinical implications.

Mechanistic understanding of degradation in bioerodible polymers for drug delivery

AIChE Journal ◽  
2002 ◽  
Vol 48 (12) ◽  
pp. 2960-2970 ◽  
Author(s):  
Domenico Larobina ◽  
Giuseppe Mensitieri ◽  
Matt J. Kipper ◽  
Balaji Narasimhan
Keyword(s):  
Drug Delivery ◽  
Mechanistic Understanding

scholarly journals Clinical implications of novel polymer and lipid based drug delivery systems

2020 ◽  
Vol 2 (3) ◽  
pp. 60-65
Author(s):  
Kallem Sharat Venkat Reddy
Keyword(s):  
Drug Delivery ◽  
Drug Delivery Systems ◽  
Dosage Forms ◽  
Delivery Systems ◽  
Clinical Implications ◽  
Clinical Settings ◽  
The Past ◽  
Long Time ◽  
Pros And Cons ◽  
Novel Drug

The use of lipids in drug delivery is not a new trend, some of the lipid dosage forms have been in use for a long time such as suppositories, creams, and emulsions. However, there has been much advancement in the designs of lipid carriers over the past decade. In the same way from the past two decades, new approaches in biodegradable and bio-reducible polymers have paved a way for many recent drug delivery systems. Applications of these novel drug delivery formulations have been promising clinically. However, each system has its pros and cons in various factors depending upon their use and intended route of administration. This review focuses on upbringing the challenges in the use of novel lipid and polymer drug delivery systems in clinical settings and few insights on how to overcome them.

scholarly journals Emerging trends in clinical implications of bio-conjugated silver nanoparticles in drug delivery

2020 ◽  
Vol 35 ◽  
pp. 100244 ◽  
Author(s):  
Parteek Prasher ◽  
Mousmee Sharma ◽  
Harish Mudila ◽  
Gaurav Gupta ◽  
Abhishek Kumar Sharma ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Silver Nanoparticles ◽  
Clinical Implications ◽  
Emerging Trends

Stomach pH before vs. after different bariatric surgery procedures: Clinical implications for drug delivery

2021 ◽  
Vol 160 ◽  
pp. 152-157
Author(s):  
Daniel Porat ◽  
Julie Vaynshtein ◽  
Roni Gibori ◽  
Opal Avramoff ◽  
Gad Shaked ◽  
...  
Keyword(s):  
Bariatric Surgery ◽  
Drug Delivery ◽  
Clinical Implications ◽  
Stomach Ph

scholarly journals Clinical implications of polymers and lipids in designing drug delivery systems in geriatric use

2020 ◽  
Vol 2 (3) ◽  
pp. 66-70
Author(s):  
Sai Raj Kappari
Keyword(s):  
Older Adults ◽  
Drug Delivery ◽  
Drug Delivery Systems ◽  
Drug Carrier ◽  
The United States ◽  
Delivery Systems ◽  
Clinical Implications ◽  
Drug Bioavailability ◽  
Advantages And Disadvantages ◽  
Polymer Hybrids

This paper will emphasize some of the clinical implications of polymers and lipids in designing drug delivery systems in the geriatric population. This article will give us an overview of the advantages and disadvantages of polymers and lipids in formulating DDS in individuals over 65 in the United States. Lipid polymer hybrids can be advantageous in systemic drug bioavailability to patients who have decreased drug carrier capacity. Older adults may benefit from lipid polymer hybrids as it enhances drug delivery and drug targeting process. Most of the older adults use a minimum of 4 to 6 medications for a variety of medical ailments and conditions. Polypharmacy may be an advent situation in some of the cases, which can be reduced by innovative drug delivery options.

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