scholarly journals Telescopic Denture

2018 ◽  
Vol 12 (1) ◽  
pp. 246-254 ◽  
Author(s):  
Mohammad Ayham Hakkoum ◽  
Ghassan Wazir
Keyword(s):  
Clinical Applications ◽  
Double Crown ◽  
Different Types

Aim: This article explains the concept of telescopic denture. Procedure: It describes the different types of telescopic attachment (or double crown), and provides an overview of the advantages and the disadvantages of this type of prosthodontic treatment. Conclusion: The indications and the clinical applications of telescopic denture are discussed.

scholarly journals Traditional uses, phytochemistry, pharmacology and toxicity of Arisaema (Areaceae): a review

2021 ◽  
Vol 45 (1) ◽  
Author(s):  
Heena Ali ◽  
Ubaid Yaqoob
Keyword(s):  
Skin Irritation ◽  
Clinical Applications ◽  
Human Populations ◽  
Main Body ◽  
Anticancer Activities ◽  
Medicinal Uses ◽  
The World ◽  
Different Types ◽  
Tropical Areas ◽  
Medicinal Properties

Abstract Background The genus Arisaema (Areaceae), popularly known as cobra lilies and jack in pulpit is mainly found in temperate to tropical areas of all continents except South America, Europe and Australia and contain about more than 250 species. Arisaema genus is being used by the different folks of human populations for medicinal as well as food purposes. Arisaema plants are used for the treatment of different types of diseases. There have been several attempts to highlight different aspects of genus Arisaema by describing it in terms of phytochemistry and medicinal uses. The present study is, however, an attempt to put together all the former data available related to the phytochemistry and medicinal uses of genus Arisaema. Main body The phytochemicals of the plant include alkaloids, phenols, terpenes, flavonoids, lectins, saponins, glycosides, triterpenoids, stigmasterols, n-alkanes, n-alkanols sitosterols, campesterol, oxalates, coumarins, tannins etc. Moreover, the properties such as antioxidant, antifungal, antibacterial, insecticidal, antimicrobial, cytotoxic, nematocidal, antiallergic antitumour and anticancer activities are also shown by the plants belonging to genus Arisaema. Arisaema plants have been traditionally used to treat various ailments such as resolving phlegm, dampness, and to treat asthma, bronchitis, cold, cough, and laryngitis etc. It has been found that there are several species which are toxic by nature. The development of clinical applications of arisaematis rhizomes had been seriously constrained due to its toxic properties like, mouth and lingua pain, even respiration slowing and suffocation, mucous membrane and skin irritation etc. and this toxicity of arisaematis rhizomes is due to raphide components. Conclusions The collection of data available on the phytochemistry of genus Arisaema is not sufficient as further work is required to do on phytochemical and medicinal basis. The data available on phytochemistry and medicinal properties of the plants belonging to genus Arisaema throws light on various species of Arisaema which are medicinally important and have been exploited to treat different types of diseases in the world.

A review of chemistry and pharmacology of Piperidine alkaloids of Pinus and related genera

2021 ◽  
Vol 22 ◽  
Author(s):  
Lav Singh ◽  
Atul K. Upadhyay ◽  
Pooja Dixit ◽  
Arpit Singh ◽  
Divyanshu yadav ◽  
...  
Keyword(s):  
Drug Research ◽  
Clinical Applications ◽  
Western Himalayas ◽  
Biological Functions ◽  
Piperidine Alkaloids ◽  
Therapeutic Application ◽  
Different Types ◽  
Limited Scale ◽  
North Western ◽  
Therapeutic Profile

Background: Pinus and other related conifers belonging to family pinaceae are most commonly used medicinal plants in Indian North-western Himalayas. Various parts of these plants including needles are source of several well known alkaloids. Of all the alkaloids, piperidine group is one of important component and hold considerable medicinal importance. Methods: The group of alkaloids was initially identified from genus Piper through which a large variety of piperidine molecules have been extracted. The planar structure of this heterocyclic nucleus enables acetamide groups to be added at various ring configurations. Results: In the area of drug research, the piperidine heterocycle has gained considerable interest. To produce a new therapeutic profile, the broad range of its therapeutic application paved the way for researchers to implant the nucleus from time to time in diversified pharmacophores. Discussion: However, biological functions of piperidine metabolites have been mostly examined on a limited scale and that most of the findings are thus preliminary. We have tried to present different clinical applications of piperidine alkaloids in this study that researchers have already attempted to demystify from time to time. Conclusion: Given the importance of the piperidine nucleus, the study will enable the researcher to produce scaffolds of the highest therapeutic efficacy. We have also illustrated different types of piperidine, its sources in different member of family pinaceae with special emphasis on Pinus.

scholarly journals Biochemistry, Safety, Pharmacological Activities, and Clinical Applications of Turmeric: A Mechanistic Review

2020 ◽  
Vol 2020 ◽  
pp. 1-14 ◽  
Author(s):  
Rabia Shabir Ahmad ◽  
Muhammad Bilal Hussain ◽  
Muhammad Tauseef Sultan ◽  
Muhammad Sajid Arshad ◽  
Marwa Waheed ◽  
...  
Keyword(s):  
Clinical Research ◽  
Biological Activities ◽  
Curcuma Longa ◽  
Clinical Applications ◽  
Pharmacological Activities ◽  
Neuroprotective Effects ◽  
Wide Range ◽  
Different Types ◽  
Safety And Toxicity ◽  
Anti Inflammatory

Turmeric (Curcuma longa L.) is a popular natural drug, traditionally used for the treatment of a wide range of diseases. Its root, as its most popular part used for medicinal purposes, contains different types of phytochemicals and minerals. This review summarizes what is currently known on biochemistry, safety, pharmacological activities (mechanistically), and clinical applications of turmeric. In short, curcumin is considered as the fundamental constituent in ground turmeric rhizome. Turmeric possesses several biological activities including anti-inflammatory, antioxidant, anticancer, antimutagenic, antimicrobial, antiobesity, hypolipidemic, cardioprotective, and neuroprotective effects. These reported pharmacologic activities make turmeric an important option for further clinical research. Also, there is a discussion on its safety and toxicity.

scholarly journals Control of Differentiation of Human Mesenchymal Stem Cells by Altering the Geometry of Nanofibers

2012 ◽  
Vol 2012 ◽  
pp. 1-9 ◽  
Author(s):  
Satoshi Fujita ◽  
Harue Shimizu ◽  
Shin-ichiro Suye
Keyword(s):  
Stem Cells ◽  
Mesenchymal Stem Cells ◽  
Human Mesenchymal Stem Cells ◽  
Clinical Applications ◽  
Soluble Factors ◽  
Precise Control ◽  
Mixed Medium ◽  
Aligned Nanofibers ◽  
Different Types ◽  
Msc Differentiation

Effective differentiation of mesenchymal stem cells (MSCs) is required for clinical applications. To control MSC differentiation, induction media containing different types of soluble factors have been used to date; however, it remains challenging to obtain a uniformly differentiated population of an appropriate quality for clinical application by this approach. We attempted to develop nanofiber scaffolds for effective MSC differentiation by mimicking anisotropy of the extracellular matrix structure, to assess whether differentiation of these cells can be controlled by using geometrically different scaffolds. We evaluated MSC differentiation on aligned and random nanofibers, fabricated by electrospinning. We found that induction of MSCs into adipocytes was markedly more inhibited on random nanofibers than on aligned nanofibers. In addition, adipoinduction on aligned nanofibers was also inhibited in the presence of mixed adipoinduction and osteoinduction medium, although osteoinduction was not affected by a change in scaffold geometry. Thus, we have achieved localized control over the direction of differentiation through changes in the alignment of the scaffold even in the presence of a mixed medium. These findings indicate that precise control of MSC differentiation can be attained by using scaffolds with different geometry, rather than by the conventional use of soluble factors in the medium.

scholarly journals Mechanical Properties of Nanotextured Titanium Orthopedic Screws for Clinical Applications

2013 ◽  
Vol 7 (2) ◽  
Author(s):  
Stephane Descamps ◽  
Komla O. Awitor ◽  
Vincent Raspal ◽  
Matthew B. Johnson ◽  
Roshan S. P. Bokalawela ◽  
...  
Keyword(s):  
Mechanical Properties ◽  
Hydrofluoric Acid ◽  
Clinical Applications ◽  
Electrochemical Anodization ◽  
Hydrofluoric Acid Solution ◽  
Commercial Titanium ◽  
Different Types ◽  
Anodized Titanium ◽  
Titanium Foils ◽  
Independent Assessment

In this work, we modified the topography of commercial titanium orthopedic screws using electrochemical anodization in a 0.4 wt% hydrofluoric acid solution to produce titanium dioxide nanotube layers. The morphology of the nanotube layers were characterized using scanning electron microscopy. The mechanical properties of the nanotube layers were investigated by screwing and unscrewing an anodized screw into several different types of human bone while the torsional force applied to the screwdriver was measured using a torque screwdriver. The range of torsional force applied to the screwdriver was between 5 and 80 cN·m. Independent assessment of the mechanical properties of the same surfaces was performed on simple anodized titanium foils using a triboindenter. Results showed that the fabricated nanotube layers can resist mechanical stresses close to those found in clinical situations.

scholarly journals Development of a Systematic Course On Orthodontic Temporary Anchorage Devices (TADs) for Orthodontic Residency Program

2021 ◽  
Author(s):  
Ziwei Tang ◽  
Yanzi Gao ◽  
Yiyin Chen ◽  
Lingling Pu ◽  
Lu Liu ◽  
...  
Keyword(s):  
Clinical Practice ◽  
Graduate Students ◽  
Residency Program ◽  
Clinical Applications ◽  
West China Hospital ◽  
West China ◽  
Temporary Anchorage Devices ◽  
Different Types ◽  
Insertion Techniques ◽  
Baseline Levels

Abstract Background: Orthodontic temporary anchorage devices (TADs) offer absolute anchorage for clinical orthodontics. No systematic course on TADs has been described so far. The objectives of this study were to develop a systematic course on orthodontic TADs and to determine its teaching outcome.Methods: Five modules (fundamentals, anatomic sites, clinical applications, complications and insertion techniques, FACCI) were designed in this FACCI course on TADs. A total of 61 orthodontic graduate students from Department of Orthodontics, West China Hospital of Stomatology, Sichuan University were enrolled in this study. Baseline levels on the use of TADs were surveyed through a before-course questionnaire and the teaching outcomes were assessed through an after-course questionnaire.Results: After the course, significantly more students were willing to insert TADs by themselves (p<0.001). Students were significantly more familiar with the clinical applications of TADs for different types of tooth movements (p<0.001) and the insertion techniques of TADs at different anatomic sites (p<0.001). Before the course, most of the students had no knowledge on addressing TADs-associated complication and they were significantly more familiar with the techniques and skills of addressing TADs-associated complication after the course (p<0.001).Conclusions: The FACCI course on orthodontic TADs was effective and promoted the clinical applications of TADs in clinical practice among orthodontic graduate students.

scholarly journals Nanomaterials as Delivery Vehicles and Components of New Strategies to Combat Bacterial Infections: Advantages and Limitations

2019 ◽  
Vol 7 (9) ◽  
pp. 356 ◽  
Author(s):  
Atanu Naskar ◽  
Kwang-sun Kim
Keyword(s):  
Bacterial Infections ◽  
Antibacterial Agents ◽  
Antimicrobial Agents ◽  
Multidrug Resistant ◽  
Clinical Applications ◽  
Human Beings ◽  
Different Types ◽  
Life Threatening ◽  
Delivery Vehicles ◽  
New Strategies

Life-threatening bacterial infections have been well-controlled by antibiotic therapies and this approach has greatly improved the health and lifespan of human beings. However, the rapid and worldwide emergence of multidrug resistant (MDR) bacteria has forced researchers to find alternative treatments for MDR infections as MDR bacteria can sometimes resist all the present day antibiotic therapies. In this respect, nanomaterials have emerged as innovative antimicrobial agents that can be a potential solution against MDR bacteria. The present review discusses the advantages of nanomaterials as potential medical means and carriers of antibacterial activity, the types of nanomaterials used for antibacterial agents, strategies to tackle toxicity of nanomaterials for clinical applications, and limitations which need extensive studies to overcome. The current progress of using different types of nanomaterials, including new emerging strategies for the single purpose of combating bacterial infections, is also discussed in detail.

Clinical Applications of Therapeutic Modalities Among Collegiate Athletic Trainers, Part II: Thermotherapy

2016 ◽  
Vol 21 (1) ◽  
pp. 68-74
Author(s):  
Jeremy R. Hawkins ◽  
Shawn W. Hawkins
Keyword(s):  
Clinical Outcomes ◽  
Treatment Guidelines ◽  
Current Knowledge ◽  
Athletic Trainers ◽  
Clinical Applications ◽  
Therapeutic Modalities ◽  
Different Types ◽  
Survey Results ◽  
Collegiate Athletic Trainers

Thermotherapy is commonly used by athletic trainers. Data are lacking as to how athletic trainers treat common injuries with thermotherapy. The purpose of this study was to ascertain how collegiate athletic trainers approach the use of thermotherapy and whether that usage reflects what current knowledge we have of thermotherapy. Survey results indicated respondents took three different approaches to the treatment of three different types of injuries. The majority of their approaches were applied according to current knowledge. Treatment guidelines could be strengthened with additional clinical outcomes data. Certain aspects of the application of the different thermotherapies should be reviewed and use adjusted accordingly.

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