scholarly journals Traditional uses, phytochemistry, pharmacology and toxicity of Arisaema (Areaceae): a review

2021 ◽  
Vol 45 (1) ◽  
Author(s):  
Heena Ali ◽  
Ubaid Yaqoob

Abstract Background The genus Arisaema (Areaceae), popularly known as cobra lilies and jack in pulpit is mainly found in temperate to tropical areas of all continents except South America, Europe and Australia and contain about more than 250 species. Arisaema genus is being used by the different folks of human populations for medicinal as well as food purposes. Arisaema plants are used for the treatment of different types of diseases. There have been several attempts to highlight different aspects of genus Arisaema by describing it in terms of phytochemistry and medicinal uses. The present study is, however, an attempt to put together all the former data available related to the phytochemistry and medicinal uses of genus Arisaema. Main body The phytochemicals of the plant include alkaloids, phenols, terpenes, flavonoids, lectins, saponins, glycosides, triterpenoids, stigmasterols, n-alkanes, n-alkanols sitosterols, campesterol, oxalates, coumarins, tannins etc. Moreover, the properties such as antioxidant, antifungal, antibacterial, insecticidal, antimicrobial, cytotoxic, nematocidal, antiallergic antitumour and anticancer activities are also shown by the plants belonging to genus Arisaema. Arisaema plants have been traditionally used to treat various ailments such as resolving phlegm, dampness, and to treat asthma, bronchitis, cold, cough, and laryngitis etc. It has been found that there are several species which are toxic by nature. The development of clinical applications of arisaematis rhizomes had been seriously constrained due to its toxic properties like, mouth and lingua pain, even respiration slowing and suffocation, mucous membrane and skin irritation etc. and this toxicity of arisaematis rhizomes is due to raphide components. Conclusions The collection of data available on the phytochemistry of genus Arisaema is not sufficient as further work is required to do on phytochemical and medicinal basis. The data available on phytochemistry and medicinal properties of the plants belonging to genus Arisaema throws light on various species of Arisaema which are medicinally important and have been exploited to treat different types of diseases in the world.

Author(s):  
Neha Gaonkar

The aim of this work was to systematically review and Meta-analyze the researches done on extra pharmacopoeial drugs (anukta dravyas) belonging to Terminalia genus. Terminalia is the second largest genus of family Combrataceae. Plants of the genus Terminalia are amongst the most widely used plants for traditional medicinal purposes worldwide. Many species are used for their antibacterial, antifungal, antiprotozoal, antiviral, antidiarrhoeal, analgesic, antimalarial, anti oxidant, anti inflammatory and anticancer activities. Indeed, the Indian species Terminalia chebula is known as the king of plants in Ayurveda due to its broad range of medicinal uses. However, apart from the reported ethnopharmacological uses of many Terminalia species, surprisingly few studies have rigorously examined this important genus for their medical properties/mechanisms. The last decade has seen a large increase in the number of studies into the use of Terminalia species as therapeutic agents. Data collected till 2018, showed around 120 different databases, articles and researches done on medicinal properties of plants belonging to Terminalia species. It was observed that out of the 250 species of Terminalia genus, research work of 80 plants was done which claimed their potential as medicines.


2021 ◽  
Vol 45 (1) ◽  
Author(s):  
Agnese Di Napoli ◽  
Pietro Zucchetti

Abstract Background Taraxacum officinale (G.H. Weber ex Wiggers), commonly known as dandelion, is a herbaceous plant native to North America, Europe and Asia. This plant has been used for health purposes since ancient times. The phytochemicals present in different parts of the plant are responsible for its medicinal properties. In this review, we describe the main health properties of Taraxacum officinale. Main body of the abstract We searched for the main medicinal properties of Taraxacum officinale in the scientific literature, using the PubMed database. We selected 54 studies and we described twelve therapeutic properties, which are reported in previous studies. These properties are diuretic, hepatoprotective, anticolitis, immunoprotective, antiviral, antifungal, antibacterial, antiarthritic, antidiabetic, antiobesity, antioxidant and anticancer effects. We also found that the most frequently reported therapeutic effects include hepatoprotective, antioxidant and anticancer activities. Short conclusion In this review, we describe the medicinal properties of Taraxacum officinale reported in previous studies. Antioxidant, hepatoprotective and anticancer effects are mostly found in the scientific literature.


2018 ◽  
Vol 2 (2) ◽  
pp. 35-41
Author(s):  
Satheesh Babu Natarajan ◽  
Sreemoy Kanti Das ◽  
Suriyakala Perumal Chandran ◽  
Aung Myo Oo ◽  
Sowmya Shar Kanneppady ◽  
...  

Diabetic wounds (DW) are a chronic, non-healing wound on the feet of diabetic patients that pose a serious challenge to world health. Around 84% of diabetic patients undergo lower leg amputations. Though numerous topical and systemic drugs have been used to heal the DW, these drugs have led to the emergence and subsequent rapid overgrowth of resistant bacterial strains, side effects and toxicity. Many herbal plants have very important role in wound healing because they promote the natural repair mechanisms. Moringaoleifera (MO) is an important medicinal plant which has an impressive range of medicinal uses including antimicrobial, anti-inflammatory, antidiabetic, antioxidant and anticancer activities. Recently few researchers reported that MO extracts have effective wound healing property due to the presence of rich flavonoids and vicenin-2. The objective of the present study was to develop hydrogel formulations loaded with Moringaoleifera leaves extract. The prepared hydrogels were evaluated for physical appearance, rheological behavior, skin irritation and wound-healing power in streptozotocin-induced diabetic male wistar albino rats. Results showed that all hydrogel formulations exhibited good and acceptable physical properties. All the animals tolerated the applied gels and no signs of irritations were noticed during the skin irritation study. The in-vivo wound healing studies showed a time dependent increase in percentage of wound, a contraction which is higher than that produced by the control groups. These contractions were statistically significant (P<0.001), during the first 10 days of the study with MO-Hydrogel administration. The MO-hydrogel showed the highest percent wound contraction with complete wound closure and epithelization was observed on 7thday of wound induction.


2016 ◽  
Vol 4 (1) ◽  
pp. 15-20 ◽  
Author(s):  
Ritesh Kumar Sharma ◽  
Anjana Goel ◽  
A. K. Bhatia

Plants play a major role on the earth and human beings depend on plants because of their medicinal properties. About 80% of the world population using plants as a medicinal drugs because plants have no side effects and show synergistic effect unlike modern medicine. In the present study, review and authentication of the various aspects of the plant Lawsonia inermis was carried out. This plant is mainly present in subtropical and tropical areas and is used in all over the world. The common name of L. inermis is Henna and Mehndi. It has been used for over 9000 years for their cosmetic values as a dye. Traditionally, in Asian countries like India and Pakistan, plant leaves are applied to hands, hairs and feet. Morphologically the plant is a small tree or shrub. L. inermis is cultivated for roots, flowers, stem bark and seeds for their medicinal uses. Proteins, carbohydrates and fatty acid are primary metabolites along with secondary metabolite such as tannins, quinines, terpenoids, coumarins etc which are present in L. inermis plant. Phytochemical constituents of L. inermis are responsible for its analgesic, anti-inflammatory, hepatoprotective and hypoglycaemic properties. The plant has also been reported for antibacterial, antifungal, immunostimulatory, antioxidant and cytotoxic activity. Presence of these properties in L. inermis plant develops it as medicine against various pathogenic organism and diseases. This review gives a wide view on the phytochemistry, pharmacological properties and traditional uses of the plant.Int J Appl Sci Biotechnol, Vol 4(1): 15-20


Author(s):  
Manish Kapoor ◽  
Gurdeep Kaur ◽  
Navneet Kaur ◽  
Chanchal Sharma ◽  
Kajal Batra ◽  
...  

The genus Hibiscus belongs to the mallow family, Malvaceae comprising of about 275 species growing in tropical and sub tropical areas. The various species of genus Hibiscus have been used as traditional medicine all over the world. There are numerous reports of their traditional medicinal uses in various countries like India, Nigeria, China, and Srilanka etc. to cure various ailments such as hypertension, cardiac diseases, stomach-ache, urine problems, skin diseases and many more. Based on the historical knowledge, various pharmacological and phytochemical studies on some species of the genus Hibiscus have been done. Nevertheless, there are no up-to-date articles published which can provide an overview of pharmacological effects of the genus Hibiscus. Therefore, the main objective of the review article is to provide a systematic comprehensive summary of traditional uses, phytochemistry and pharmacology of the genus Hibiscus and to build up a correlation between its traditional ethano-botanical uses and pharmacological activities so as to find some advanced research opportunities in this field. The given information on the ethano-botanical uses, phytoconstituents and various medicinal properties of the genus Hibiscus was gathered from the online scientific databases through search in Google, Google Scholar, Science Direct, NCBI, Pubmed, Springer Link, Research Gate by using some keywords as. Besides these websites other published literature and unpublished Ph.D. thesis and M.Sc. dissertation were also consulted. Previously conducted research revealed that the genus contains good amount of phytoconstituents such as antioxidants, phytosterols, saponins, lignin, essential oils, glycosides, and anthocyanins etc. Presence of these bioactive compounds in the crude extracts of the plants make it suitable for various medicinal properties like anti inflammatory, anti-diabetic, anti-obesity, anti-proliferative, anti-ulcer, hypersensitive, hypolipidemic, hepatoprotective, nephroprotective and many more. Additionally, this review article showed that mainly two species of the genus i.e. H. rosa-sinensis and H. sabdariffa have been explored for their pharmacological activities. There are few reports on some other species like H. tiliaceous, H. microanthus, H. asper, H. acetosella. This review highlights the medicinal potential of the plant Hibiscus due to its unique blend of phytochemicals. These phytoconstituents can be further assessed and subjected to clinical trials for their proper validations. Although large amount of the data regarding pharmacological effects has already been added to the existing reservoir but still potential of certain species like H. radiatus, H. hirtus, H. moschetous, H. trionum and many more is not yet unveiled and can be considered as future prospects that need to be worked out.  Graphical Abstract: 


2018 ◽  
Vol 13 (3) ◽  
pp. 1934578X1801300
Author(s):  
Sara Musaddiq ◽  
Kiran Mustafa ◽  
Sajjad Ahmad ◽  
Samina Aslam ◽  
Basharat Ali ◽  
...  

Aerva plants are known widely for their exceptional medicinal uses. They have been employed conventionally for their medicinal properties by the common folk in several regions of the world. This indicates the efficacy of these remarkable herbs. They are also known for their multiple biological activities such as antioxidant, antibacterial, antilithiatic, hepatoprotective, antidiabetic, anticancer, antihyperlipidemic and nephroprotective potential. These pharmacological actions are associated with the presence of valuable nutrients and biochemical compounds such as sterols/terpenes, flavonoids, alkaloids, phenolics and sugars. The proper utilization of the substances obtained from these plants can enhance the finesse of the capabilities of these plants. These plants are not only medicinally important but are significantly serving several other scientific purposes. In the prospect of medicinal, scientific uses and the bioavailability of precious chemicals of Aerva species, a comprehensive review is compiled, which focuses on the detailed profile of biochemical compounds, pharmacological functions and biological activities of Aerva plants. The review also discusses the synthetic importance and the toxicity of these plants. The study aims to compile comprehensively what is already done and what more is needed to be done in the future investigations related to Aerva species.


2020 ◽  
Vol 5 (3) ◽  

Psoriasis is an autoimmune condition, which results in the body attacking itself. It occurs in the age group of 30 years to ≥ 65 years. More than 100 million individuals around the world are affected with this disease. The main objective of this study is to provide patients with more effective and safer treatment to this disease. More than 10 million cases per year in India are being recorded. Around 15% of cases emerge before the age of 10 years. In the case of psoriasis, white blood cells known as T cells mistakenly attack the skin cells. Around 80% of people have mild psoriasis, and the other 20% have moderate to severe psoriasis. There are different types of psoriasis they are Plaque psoriasis occurs in about 80-90% of people, it appears as raised, inflamed, red lesions, covered by a silvery, white scales, usually on the elbows, knees, scalp, and lower back. Inverse psoriasis appears in the different parts like armpits, the groin, under the breasts, and in other skin folds such as the buttocks and around the genitals. Aloe vera originates from the Arabian Peninsula, but grows wild in tropical, semi-tropical, and arid climates around the world. It is cultivated for agricultural and medicinal uses. The species is also used for decorative purposes and grows successfully indoors as a potted plant also used for herbal medicine and cosmetic products. Argemone Mexicana (Mexican poppy, Mexican prickly poppy, flowering thistle, cardo or cardosanto) is a species of poppy found in Mexico and now widely naturalized in many parts of the world.


2021 ◽  
Vol 16 (11) ◽  
pp. 177-185
Author(s):  
Praveen Pathak ◽  
Chandra Kant Sharma

Cancer is considered to be a dreaded disease throughout the world. There are many different types of drugs available to treat this disease. Nowadays, scientists are engaged to develop drugs at the nanoscale. The nano-drugs are found to exhibit more efficiency and accuracy. Nanotechnology is an emerging technology dealing with the development of nano-particles and nanostructures. These substances have acquired significance because of their size, shape and potential efficiency as well as specificity. Nano-particles mediated drugs were very focusing, emerging objective regarding the use of different types of nanoparticles as carrier to treat cancerous tumors and cancer cells. Medicinal lysis or synthesis of nanoparticles with biological procedures has become very much significant due to their specific efficacy and lesser harms compared to other available medicines used for cancer. In this review, green plants, their active compounds and metallic nano-particles are discussed with emphasis on their anticancer activities and properties.


Author(s):  
Y. Arockia Suganthi ◽  
Chitra K. ◽  
J. Magelin Mary

Dengue fever is a painful mosquito-borne infection caused by different types of virus in various localities of the world. There is no particular medicine or vaccine to treat person suffering from dengue fever. Dengue viruses are transmitted by the bite of female Aedes (Ae) mosquitoes. Dengue fever viruses are mainly transmitted by Aedes which can be active in tropical or subtropical climates. Aedes Aegypti is the key step to avoid infection transmission to save millions of people in all over the world. This paper provides a standard guideline in the planning of dengue prevention and control measures. At the same time gives the priorities including clinical management and hospitalized dengue patients have to address essentially.


Author(s):  
T. M. Robinson

This article argues the following five claims: 1. Plato’s description of the origins of cosmos in the Timaeus is not a myth, nor something unlikely: when he called it an eikos mythos or eikos logos, he meant a likely or trustworthy account on this very subject. 2. Among the details in this account, the following are prominent and surprising: a) the world was fashioned in time, in that precise point that was the beginning of time; b) several kinds of duration can be distinguished in cosmology (mainly eternity, sempiternity, perpetuity and time); and c) space is an entity characterized by movement and tension. 3. In the Statesman, Plato repeats much the same thing, adding this time the strange notion that the universe’s circular movement is periodically reversed. 4. In spite of the important differences in detail, there is a striking similarity between Plato’s account of the origins of the world and the explanation adopted by much of modern cosmology. 5. What Plato shares with so many instances of recent thought is here termed “cosmological imaginativity”. A first section of the paper deals exclusively with the Timaeus. Claims 1 and 2a are supported by a revision of the meanings of mythos and logos, followed by brief reference and discussion of the argument at Timaeus 27d, leading to the conclusion that Plato affirms that the ever-changing world has indeed had a beginning in time. Claim 2b describes five different types of duration, corresponding to Forms, the Demiurge, Space, the [empirical] world and its contents, physical objects. The second section is concerned with the myth in the Statesman, discussing it as a parallel and describing its peculiar turn to the Timaeus’ cosmology and cosmogony, a complex spheric and dynamic model. After digressing into some important ideas in modern cosmology, touching especially on affinities of some of Einstein’s ideas with of Plato’s own, the paper closes with a discussion of cosmological imaginativity, oriented to recover and recognize fully Plato’s greatness as a cosmologist.


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