scholarly journals Retention Loss of Resin Based Fissure Sealants - a Valid Predictor for Clinical Outcome?

2013 ◽  
Vol 7 (1) ◽  
pp. 102-108 ◽  
Author(s):  
Steffen Mickenautsch ◽  
Veerasamy Yengopal
Keyword(s):  
Clinical Outcome ◽  
Null Hypothesis ◽  
Wilcoxon Test ◽  
Sign Test ◽  
Fissure Sealants ◽  
Control Data ◽  
Retention Loss ◽  
Number Of Teeth ◽  
Valid Predictor ◽  
Sealant Retention

Purpose: The null-hypothesis that retention loss of resin fissure sealants predicts caries manifestation no more accurately than random values was tested. Methods: Systematic reviews were checked and electronic databases searched for clinical trials. Trials reporting on the retention of resin sealants and caries occurrence in permanent molar teeth, with minimum 24-month follow-up period, were included. Extracted data: number of sealed teeth, number of teeth without completely retained sealants, number of sealed teeth with caries. The number of teeth with complete sealant retention and absence of carious lesions/cavities was calculated; the predictive outcomes: true/false positive; false/true negative were established. Random values were generated as control-data. Diagnostic Odds ratios (DOR) were computed and tested for statistical difference. Summary Receiver Operating Characteristic curves were plotted. Results: 95 trials were found. Median DOR values were 1.21 and 0.28 for test- and control data, respectively. Wilcoxon test (z = 0.56; p = 0.58) and Sign test (z = 1.38; p = 0.17) results were statistically non-significant. The null-hypothesis was not rejected. Conclusions: Predictions based on the retention loss of resin sealants, regarding caries manifestation, was no more accurate than random guesses. Sealant retention loss appears not to be a valid predictor for clinical outcome.

Pengaruh Self Help Group Terhadap Kemampuan Keluarga Dalam Merawat Klien Skizofrenia Di Poli Jiwa Puskesmas Kalitidu

2020 ◽  
Vol 10 (2) ◽  
Author(s):  
Yusuf Efendi ◽  
Errix Kristian Julianto
Keyword(s):  
Mental Disorders ◽  
Group Intervention ◽  
Family Members ◽  
Wilcoxon Test ◽  
Sign Test ◽  
Significance Level ◽  
Self Help ◽  
Before And After ◽  
Self Help Groups ◽  
Self Help Group

ABSTRAKDiera perkembangan jaman saat ini, beberapa keluarga dihadapkan dengan permasalahna tentang adanya angggota keluarga yeng mengaami gangguan jiwa, tak jarang keluarga tidak mengetahui bagaimana merawat angota keluarga dengan gangguan jiwa. Self help group pada keluarga dengan gangguan jiwa perlu dilakukan untuk membantu keluarga mengatasi permasalahannya yang diselesaikan bersama dalam kelompok. Manfaat yang didapatkan pada terapi ini adalah terdapatnya peningkatan pengetahuan keluarga tentang Skizofrenia. Peningkatan pengetahuan ini akan berdampak terhadap kemampuan keluarga dalam merawat klien Skizofrenia..Desain penelitian ini menggunakan desain pre eksperimental dengan rancangan one group pre-posttest design. Sampel pada penelitian ini adalah keluarga penderita Skizofrenia di PKU Jiwa Kalitidu yang berjumlah 32. . Data dikumpulkan menggunakan kuesioner kemudian dianalisis dengan menggunakan uji Wolcoxon sign dengan tingkat kemaknaan 0,05. Hasil penelitian menunjukkan bahwa kondisi responden sebelum dan sesudah dilakukan intervensi dengan self help group pada kemampuan merawat dengan  nilai uji wilcoxon sebesar 0,001 yang berarti ada pengaruh dari intervensi self help group dengan merawat keluarga dengan gangguan jiwa. Kata Kunci       : Self Help Group, Kemampuan Merawat, Skizofrenia   ABSTRACT. In the current era of development, some families are faced with problems about family members who suffer from mental disorders, often families do not know how to care for family members with mental disorders. Self help groups for families with mental disorders need to be done to help families overcome the problems that are solved together in a group. The benefit of this therapy is that there is an increase in family knowledge about Schizophrenia. This increase in knowledge will have an impact on the ability of families to care for Schizophrenia clients.The design of this study used a pre-experimental design with one group pre-posttest design. The sample in this study was the families of Schizophrenics in  Kalitidu public helath centre, amounting to 32.. Data were collected using a questionnaire and then analyzed using the Wolcoxon sign test with a significance level of 0.05.The results showed that the condition of the respondents before and after the intervention with self help group on the ability to care for Wilcoxon test value of 0.001, which means there is an influence of self help group intervention by caring for families with mental disorders. Keywords: Self Help Group, Caring Ability, Schizophrenia

scholarly journals Assessment of Changes in the Hemoglobin Level under the Influence of Comprehensive Spa Therapy Using Therapeutic Radon-Sulfur Waters and Its Correlation with Free Radical Reactions

2020 ◽  
Vol 2020 ◽  
pp. 1-6
Author(s):  
Jadwiga Kuciel-Lewandowska ◽  
Michał Kasperczak ◽  
Małgorzata Paprocka-Borowicz
Keyword(s):  
Free Radical ◽  
Hemoglobin Level ◽  
Wilcoxon Test ◽  
Radical Reactions ◽  
Sign Test ◽  
Spa Therapy ◽  
Main Function ◽  
Free Radical Reactions ◽  
Spa Treatment ◽  
The Mean

Introduction. Hemoglobin is a protein present in erythrocytes of higher organisms. Its main function is to transport oxygen from the lungs to tissues and carbon dioxide from tissues to the lungs. Hemoglobin contains Fe2+, catalyzes free radical reactions, and may initiate oxidation reactions by enzymatic and nonenzymatic degradation. The aim of the study was to evaluate the effect of balneophysiotherapy on the hemoglobin level in osteoarthritis patients and to try to assess the association of those metabolic changes with free radical reactions. Materials and Methods. The study was conducted in Przerzeczyn-Zdrój spa resort. It included patients receiving spa treatment over 21-day sessions. The studied group consisted of n = 122 patients with joint and back pain due to osteoarthritis or disc herniation. Their age ranged between 32 and 67 years with a mean age of 53.5. Blood samples were collected before treatment and after 21 days at the spa. Standard tests were used. The results were statistically analyzed using the sign test and the Wilcoxon test. Results. In the study group, we observed a drop in the hemoglobin level following spa treatment. Before treatment, the mean hemoglobin level was 14.1549 g%, and after treatment, it was 14.0008 g%. Conclusions. (1) In the study, we concluded that balneophysiotherapy in osteoarthritis patients resulted in a decrease in the mean hemoglobin level. (2) The decrease in the mean hemoglobin level in osteoarthritis patients treated at the spa resort may indicate an association with free radical reactions. This trial was registered with NCT03405350.

scholarly journals Bone dehiscence formation during orthodontic tooth movement through atrophic alveolar ridges

2019 ◽  
Vol 90 (3) ◽  
pp. 321-329
Author(s):  
Adilson Luiz Ramos ◽  
Monique Cimão dos Santos ◽  
Márcio Rodrigues de Almeida ◽  
Carlos Flores Mir
Keyword(s):  
Null Hypothesis ◽  
Alveolar Bone ◽  
Tooth Movement ◽  
Linear Regression Analysis ◽  
Orthodontic Tooth Movement ◽  
Wilcoxon Test ◽  
Control Group ◽  
Multivariate Linear Regression Analysis ◽  
Alveolar Ridge ◽  
Bone Height

ABSTRACT Objectives To test the null hypothesis that there is no difference in bone dehiscence formation before and after orthodontic tooth movement through an atrophic alveolar ridge. Material and Methods This longitudinal retrospective study evaluated pretreatment and posttreatment cone-beam computed tomography imaging of 15 adult patients. Twenty-five teeth were moved through the atrophic alveolar bone, whereas 25 teeth not subjected to translational movement were considered controls. The distances between the cementoenamel junction and the alveolar bone crest were assessed at the mesial, distal, buccal, and lingual surfaces of all of these teeth. Data were compared using the Wilcoxon test. The Spearman correlation test and multivariate linear regression analysis were also performed. Results In general, crestal bone height was reduced around 0.5 mm in all groups in every direction. Median buccal dehiscence increased significantly (+2.25 mm) (P < .05) in teeth moved through the atrophic ridge. Control teeth also had buccal crest loss (+0.83 mm), but this was not statistically different from that of the experimental teeth. Lingual dehiscence increased significantly for the experimental (+0.17 mm) and control (+0.65 mm) groups. Mesial bone height decreased more in the control group (–0.44mm) than in the experimental group (–0.14mm). There was moderate correlation between amount of tooth movement and alveolar bone loss. Conclusions The null hypothesis was rejected as dehiscence increased after tooth movement through an atrophic alveolar ridge, mainly in the buccal plate.

scholarly journals Clinical outcome and quality of life in octogenarian patients with muscle-invasive urothelial carcinoma of the bladder treated with radical cystectomy or transurethral resection of the bladder tumor: a retrospective analysis of 143 patients

2021 ◽  
Author(s):  
Christian Rehme ◽  
Beatrix Fritsch ◽  
Luca Thomas ◽  
Stefan Istin ◽  
Carolin Burchert ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Clinical Outcome ◽  
Urothelial Carcinoma ◽  
Radical Cystectomy ◽  
Transurethral Resection ◽  
Cox Regression ◽  
Wilcoxon Test ◽  
Cancer Specific Survival ◽  
Muscle Invasive

Abstract Purpose To compare clinical outcome and quality of life (QoL) in octogenarian patients with muscle-invasive urothelial carcinoma (MIBC) either treated by radical cystectomy (RC) or transurethral resection of the tumor (TURBT). Methods We identified octogenarian patients with MIBC in our institutions since 2005. Clinical treatment outcomes and QoL were analyzed. Uni- and multivariable Cox regression analyses, two-tailed Wilcoxon test, Mann–Whitney test and Fisher’s exact test were assessed as appropriate. QoL was evaluated using FACT-G (Functional Assessment of Cancer Therapy-General) questionnaire. Results 143 patients were identified (RC: 51 cases, TURBT: 92 cases). Mean follow-up was 14 months (0–100 months). Median overall survival (OS) was 12 months in the RC group and 7 months in the TURBT group. TURBT and low preoperative hemoglobin were independent risk factors for reduced cancer-specific survival (CSS) (TURBT: p = 0.019, Hb: p = 0.008) and OS (TURBT: p = 0.026, Hb: p = 0.013) in multivariable analyses. Baseline QoL was low throughout the whole cohort. There was no difference in baseline FACT-G scoring comparing RC and TURBT (FACT-G total score (median): RC 43.7/108 vs. TURBT 44.0/108, p = 0.7144). Increased FACT-G questionnaire scoring was assessed for RC patients (median percentage score change RC 22.9%, TURBT 2.3%, p < 0.0001). Conclusion RC and TURBT are feasible treatment options for MIBC in octogenarian patients. In our cohort, RC was associated with increased CSS, OS and QoL. QoL in general was low throughout the whole cohort. Interdisciplinary decision-making has to be improved for these critically ill patients.

scholarly journals A Two-Year Clinical Evaluation of Fluoride and Non-Fluoride Resin-Based Pit-and-Fissure Sealants

2015 ◽  
Vol 26 (6) ◽  
pp. 678-684
Author(s):  
Tatiana Yuriko Kobayashi ◽  
Daniela Rios ◽  
Maria Aparecida de Andrade Moreira Machado ◽  
Thais Marchini Oliveira ◽  
Salete Moura Bonifácio da Silva
Keyword(s):  
Surface Characteristics ◽  
The Other ◽  
Occlusal Surface ◽  
Air Bubbles ◽  
Fissure Sealants ◽  
Chi Square ◽  
Pit And Fissure Sealants ◽  
Chi Square Test ◽  
Sealant Retention ◽  
Sealant Material

The aim of this study was to evaluate and compare for 24 months, the retention and surface characteristics of two pit-and-fissure sealants: Helioseal Clear and Helioseal F (Ivoclar Vivadent). The correlation between the different stages of eruption and sealant retention was also verified. Fifty children aged 6 to 8 years participated in the study, totalizing 153 teeth divided into two groups: HC (Helioseal Clear) and HF (Helioseal F). After 6, 12, 18 and 24 months, a clinical examination was performed by previously calibrated examiners. The surface characteristics and the retention of the sealants (modified RYGE & SNYDER criteria) were assessed. Analyzing the occlusal surface, HC exhibited a statistically significant higher retention at 12 (p=0.0345) and 24 months (p=0.0076). Concerning the surface characteristics, only the superficial discoloration of HC was smaller than HF, during the entire studied period. For all the other characteristics, the results of the Mann-Whitney test were highly significant at different periods (p=0.0000 to 0.0421). The frequency of air bubbles within the sealant surfaces, determined by Chi-square test, was significantly higher in HF (p=0.000:12 and 18 months to p=0.002: 6 and 24 months). HC sealant material exhibited the best performance regarding the retention and surface characteristics on the occlusal surface.

scholarly journals Changes in the level of interleukin-4 and interleukin-6 in response to angioprotective therapy in children with severe birth asphyxia

2020 ◽  
Vol 54 (1) ◽  
pp. 18-22
Author(s):  
Sergej Ovčarenko ◽  
Viktorija Danilova ◽  
Violeta Kalnicka
Keyword(s):  
Inflammatory Response ◽  
Interleukin 6 ◽  
Aerobic Glycolysis ◽  
Birth Asphyxia ◽  
Systemic Inflammatory Response ◽  
Wilcoxon Test ◽  
Interleukin 4 ◽  
Sign Test ◽  
Oxygen Utilization ◽  
Paired Samples

Objective. The development of clinical and laboratory criteria for diagnosis of systemic inflammatory response significantly expanded the use of this concept in clinical practice. The correlation between the levels of antiinflammatory and pro-inflammatory cytokines is an important aspect in regulation of systemic inflammatory response. Treatment of systemic inflammatory response includes three main links: effect on the levels of endotoxin, cytokines and the state of endothelium. Currently there is no unified approach to the solution of this problem, which determines the relevance of the topic. The aim of the research was to study the efficacy of the deproteinized hemodialysate from the newborn calf blood in systemic inflammatory response in newborns with severe asphyxia at birth. Methods. The study involved examination of 16 newborns with severe asphyxia at birth, who received a drug as part of standard therapy from the first day of the disease at a dose of 0.5 ml/kg. The study implied a follow-up assessment of interleukin-4 and interleukin-6 levels. Sign test and Wilcoxon test were used for paired samples; Kolmogorov-Smirnov and Mann-Whitney tests were used for non-paired samples. To investigate the influence of the independent variable on the dependent variable we used Kruskal-Wallis and median tests as nonparametric analogs of the variance analysis. Results. Deproteinized hemodialysate derived from the newborn calf blood is a vasoprotector and is a combination of a number of physiologically active ingredients. They stimulate oxygen utilization by tissues in hypoxic conditions, enhancing glucose transport through biological membranes, intensifying intracellular adenosine triphosphate synthesis, and increasing the proportion of aerobic glycolysis. Conclusion. Administration of deproteinized hemodialysate from the newborn calf blood in the treatment of systemic inflammatory response in newborns with severe asphyxia at birth exerts influence on biochemical pattern of systemic inflammatory response by reducing inflammation and reducing synthesis of cytokines.

scholarly journals Analysis and evaluation of urban socioeconomic dimensions

Vestnik MGSU ◽  
2021 ◽  
pp. 801-808
Author(s):  
Mourad Alashkar Eilaf ◽  
Yuri V. Alekseev ◽  
Alireza Majorzadehzahiri
Keyword(s):  
Null Hypothesis ◽  
Living Environment ◽  
Social Dimension ◽  
Wilcoxon Test ◽  
P Value ◽  
Economic Dimension ◽  
The Social ◽  
Urban Renovation ◽  
Z Value ◽  
The City

Introduction. Following any war, the destruction of cities causes severe damage to the lives of citizens, so urban planning and accelerating the process of renovation and development of a city is the priority of every country after the war, in order to reduce the damage caused by war. Since then, citizens can resume their normal living in their hometowns. The process of urban renovation and development takes a long time, and the main urban indicators should be regularly evaluated in different dimensions to find out whether the living environment has improved and the preset urban goals have been achieved. Materials and methods. In this study, the process of renovation and development of the city of Homs was analyzed by evaluating the pre-selected social and economic indicators. The sign test and the Wilcoxon test were used to evaluate and compare the indicators before and after the war. Results. The results of the research show that the null hypothesis of this research was rejected with a z-value of –3.137916 and a p-value of 0.002 in respect of the social dimension. Also, the zero hypothesis of this research is rejected in the economic dimension according to the results of the Wilcoxon test. The results show that the z-value is equal to –2.075 and the p-value is equal to 0.038, which is less than 0.50 and, hence, insignificant. The rejection of the null hypothesis and the large number of negative indicators in the social dimension indicate that the process of renovation and development of the city of Homs is very slow after the war and the city has not been able to approach the desired stable condition. Conclusions. This research has found that only 11 indicators out of 45 improved in the process of renovation and development of the city of Homs after the war if compared to the pre-war period. In fact, more than 75 % of selected indicators were negative, and this shows the slow pace of urban renovation and development with an emphasis on the sustainable city of Homs.

scholarly journals THE INFLUENCE OF PLAYING BALL TOWARD MOVEMENT ACTIVITY ABILITY TO HYPOACTIVE AUTISM CHILDREN

2019 ◽  
Vol 2 (2) ◽  
Author(s):  
Anggawati Imanniyah
Keyword(s):  
Data Analysis ◽  
Data Collection ◽  
Time Allocation ◽  
Null Hypothesis ◽  
Research Result ◽  
Sign Test ◽  
Movement Activity ◽  
Motoric Activity ◽  
Before And After ◽  
The One

Hypoactive autism children were indicated by slow motoric activity so that it caused the children difficult to move. The children tended passive and they did not have any interest to do movement activity and preferred alone when they looked their friends playing. To help hypoactive autism children in enhancing movement activity ability it required a game which attracted the children’s interest to move i.e. through playing game. The purpose of this research was to analyze movement activity ability before and after giving intervention using playing ball (passing and shooting), with time allocation 10 times meeting and 8 times intervention. This research used quantitative approach with the one group pretest posttest design. The subjects were 5 hypoactive autism children. For data analysis this research used statistic non parametric formula of sign test kind and the method of data collection applied observation and test. From the research result which was then analyzed by using sign test formula, it was obtained that the value of Z counting 1,78 while the value of Z table with critic value 5% one side test was obtained 1,64 so that Z counting 1,78 was greater than Z table1,64 it meant that null hypothesis (Ho) was refused and work hypothesis (Ha) was accepted. In this way it could be concluded that playing ball influenced toward movement activity ability of hypoactive autism children

scholarly journals Adaptive rank tests for location with generalizaed Lambda distribution scores

2017 ◽  
Vol 10 (2) ◽  
pp. 183-205
Author(s):  
Jimmy Corzo Salamanca ◽  
Arsenio HIdalgo Troya
Keyword(s):  
Simulation Study ◽  
Score Function ◽  
Wilcoxon Test ◽  
Sign Test ◽  
Rank Tests ◽  
Generalized Lambda Distribution ◽  
Nominal Size ◽  
Kurtosis Parameter

We propose adaptive rank tests for the location alternative in one sample, using as score function the percentile function of the Generalized Lambda Distribution (GLD ). We give expressions for its eciency as functions of the kurtosis parameters of the distribution used for the score function and those of the sampled distribution. A simulation study shows that the proposed tests maintain its nominal size and that this test using scores functions with small kurtosis parameter, are very ecient for samples coming from distributions with large kurtosis, overtaking the sign test and the Wilcoxon test. Reciprocally, tests which use scores from GLD  distributions with large kurtosis are more ecient when the sample comes from GLD  distributions with small kurtosis.  

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