scholarly journals Clinical and pathogenetic approaches to early rehabilitation of ischaemic stroke patients

2021 ◽  
Vol 4 (4) ◽  
pp. 373-380
Author(s):  
Pulatov Sadriddin Sayfullaevich
Keyword(s):  
Ischaemic Stroke ◽  
Social Problem ◽  
Hemorrhagic Stroke ◽  
Cerebrovascular Disorders ◽  
Epidemiological Data ◽  
High Morbidity ◽  
Stroke Patients ◽  
Stroke Prevalence ◽  
Dyscirculatory Encephalopathy ◽  
The Republic

Stroke is the most important medical and social problem, both worldwide and in Uzbekistan, owing to its high morbidity, mortality and disability rates. Uzbekistan's official statistical authorities consider cerebrovascular disease (CVD) to be a single nosological form, without distinguishing it from stroke. Given that the structure of CVDs includes both acute cerebrovascular disorders (ACS) (various types and subtypes of ischemic and hemorrhagic stroke) and chronic CVDs (various forms of so-called dyscirculatory encephalopathy), reliable epidemiological data on stroke prevalence in Uzbekistan are not available. According to the Ministry of Health of the Republic of Uzbekistan, there were 62876 cases of stroke in Uzbekistan in 2019. 15% were fatal, 10-15% relapsed and 55-70% became disabled.

scholarly journals Electrolyte disturbances and lipid profiles in ischaemic and hemorrhagic stroke patients in Aisyiyah Bojonegoro Hospital, Indonesia

2020 ◽  
Vol 8 (6) ◽  
pp. 2028
Author(s):  
Yunita Dwi Setyawati ◽  
Rila Ruis Mastura
Keyword(s):  
Ischaemic Stroke ◽  
Medical Records ◽  
Hemorrhagic Stroke ◽  
Previous History ◽  
Lipid Profiles ◽  
Electrolyte Imbalance ◽  
P Value ◽  
High Morbidity ◽  
Lipid Levels ◽  
Stroke Patients

Background: The prevalence of stroke continues to increase every year. Electrolyte imbalance and metabolic disorder can cause high morbidity and mortality of stroke. There are very few studies conducted on serum electrolytes and lipid levels in stroke patients. Authors aimed to know the electrolyte disturbance and lipid profiles in acute stroke.Methods: Retrospective case analysis was used in this study. Patients who diagnosed with hemorrhagic and ischaemic stroke in Aisyiyah Bojonegoro Hospital from January to September 2019 were selected trough electronic medical records system. Authors examine the electrolyte levels and lipid profiles. Patients with a previous history of stroke, complication that might affect electrolyte level and incomplete data in medical records were excluded. Independent T-test or Mann Whitney test were used to analyze the difference of parameters between hemorrhagic and ischaemic stroke patients. P value was considered as significant at p<0.05.Results: Most common electrolyte imbalance in both hemorrhagic and ischaemic stroke was hypokalemia which is statistically significant. Comparison between stroke patients was statistically significant for mean potassium and high density lipoprotein (HDL), while other mean serum values were not different. Potassium significantly lower (p=0.002) in hemorrhagic stroke and HDL significantly lower (p=0.034) in ischaemic stroke.Conclusions: This study reveals that hypokalemia was higher in hemorrhagic stroke and HDL was lower in ischaemic stroke. Regular monitoring of lipid levels in patients with high risk factors and correction of electrolytes imbalance for stroke patients will help in decreasing the mortality and morbidity.

Genetics

2018 ◽  
Author(s):  
Alessandro Pezzini
Keyword(s):  
Ischaemic Stroke ◽  
Association Studies ◽  
Single Gene ◽  
Cerebrovascular Disorders ◽  
Epidemiological Data ◽  
Genome Wide Association Studies ◽  
Clinical Genetic ◽  
Genome Wide ◽  
Single Gene Disorders ◽  
Near Future

Ischaemic stroke is a heterogeneous multifactorial disorder. Although epidemiological data from twin and family studies provide substantial evidence for a genetic basis for stroke, the contribution of genetic factors identified so far is small. Large progress has been made in single-gene disorders associated with ischaemic stroke, particularly at young age. By contrast, little is known about the genes associated with multifactorial stroke. The reported genome-wide association studies of ischaemic stroke have shown that no single common genetic variant imparts major risk, but data on early-onset disease are scarce in this regard. Larger studies with samples numbering in the thousands are ongoing to identify common variants with smaller effects on risk. This approach, in addition with new analytic techniques, will likely contribute to the identification of additional genes, novel pathways, and eventually novel therapeutic approaches to cerebrovascular disorders in the near future. The aims of this review are to summarize data on clinical, genetic, and epidemiologic aspects of monogenic conditions associated with juvenile ischaemic stroke, to discuss recent findings and methodological limitations regarding the genetics of sporadic ischaemic stroke in this age category, and to provide a brief overview of the potential future approaches to stroke genetics.

Diagnosis of cerebral hemorrhage before the era of computed tomography

2013 ◽  
Vol 154 (44) ◽  
pp. 1743-1746
Author(s):  
Gergely Hofgárt ◽  
Rita Szepesi ◽  
Bertalan Vámosi ◽  
László Csiba
Keyword(s):  
Computed Tomography ◽  
Cerebrospinal Fluid ◽  
Positive Predictive Value ◽  
Predictive Value ◽  
Hemorrhagic Stroke ◽  
Cranial Computed Tomography ◽  
Cerebral Stroke ◽  
Daily Routine ◽  
Stroke Patients ◽  
The Difference

Introduction: During the past decades there has been a great progress in neuroimaging methods. Cranial computed tomography is part of the daily routine now and its use allows a fast diagnosis of parenchymal hemorrhage. However, before the availability of computed tomography the differentiation between ischemic and hemorrhagic stroke was based on patient history, physical examination, percutan angiography and cerebrospinal fluid sampling, and the clinical utility could be evaluated by autopsy of deceased patients. Aim: The authors explored the diagnostic performance of cerebrospinal fluid examination for the diagnosis of ischemic and hemorrhagic stroke. Method: Data of 200 deceased stroke patients were retrospectively evaluated. All patients had liquor sampling at admission and all of them had brain autopsy. Results: Bloody or yellowish cerebrospinal fluid at admission had a positive predictive value of 87.5% for hemorrhagic stroke confirmed by autopsy, while clear cerebrospinal fluid had positive predictive value of 90.7% for ischemic stroke. Patients who had clear liquor, but autopsy revealed hemorrhagic stroke had higher protein level in the cerebrospinal fluid, but the difference was not statistically significant (p = 0.09). Conclusions: The results confirm the importance of pathological evaluation of the brain in cases deceased from cerebral stroke. With this article the authors wanted to salute for those who contributed to the development of the Hungarian neuropathology. In this year we remember the 110th anniversary of the birth, and the 60th anniversary of the death of professor Kálmán Sántha. Professor László Molnár would be 90 years old in 2013. Orv. Hetil., 154 (44), 1743–1746.

Delayed Treatment of Spinal Cord Injury In Young: A Case Report

2018 ◽  
Vol 1 (2) ◽  
pp. 15
Author(s):  
Joshua Sutikno
Keyword(s):  
Spinal Cord ◽  
Spinal Cord Injury ◽  
Traffic Accidents ◽  
Epidemiological Data ◽  
Morbidity Rate ◽  
High Morbidity ◽  
Low Back ◽  
Traditional Treatment ◽  
Delayed Treatment ◽  
Cord Injury

Background: Spinal cord injury (SCI), one of the problems caused by traffic accidents, has a high morbidity in developing country like Indonesia. In Indonesia, the use of motorcycles is increasing every year. The epidemiological data from Fatmawati Hospital of spinal cord injury in 2014 was 104 cases both traumatic and non-traumatic SCI. In this case, a young boy with worsening of SCI, delayed the treatment for about 3 months.Case: A 19 years-old male complained of limbs paralysis for the past two weeks. He felt numbness and tingling in hamstring and calf areas. From past medical history, he had a motorcycle accident 3 months prior. After the accident, he suffered from extreme low back pain, but he could still move his legs. Due to economic restrictions, the patient refused to go to the hospital, and they chose a traditional treatment. For about three months, the pain was decreasing, but he was never pain-free. As the symptoms continued to worsen, the neurosurgeon decided to decompress the spinal cord and performed discectomy. After a week of treatment, the pain disappeared, motor muscle got better, and he could feel again the sensation on the dermatome of S1. Conclusion: Early treatment is recommended to get a better outcome. The surgery is not the only treatment, rehabilitation and orthotics using are important too. Delayed treatment increases morbidity rate.

KUALITAS HIDUP PASIEN STROKE DI POLIKLINIK RAWAT JALAN RUMAH SAKIT SWASTA YOGYAKARTA

2019 ◽  
Vol 7 (3) ◽  
pp. 232-237
Author(s):  
Hana Larasati ◽  
Theresia Titin Marlina
Keyword(s):  
Quality Of Life ◽  
Social Relations ◽  
Hemorrhagic Stroke ◽  
Poor Quality ◽  
Social Dimension ◽  
Stroke Patients ◽  
Sampling System ◽  
Post Stroke ◽  
Psychological Dimension

Background: stroke is a disorder of nervous system function that occurs suddenly and is caused by brain bleeding disorders that can affect the quality of life physical dimensions, social dimensions, psychological dimensions, environmental dimensions. Based on the result of Lumbu study (2015) the number of samples were 71 people collected data using the (WHOQOL-BREF). There were 56 people (78,9%) had the poor quality of life of post stroke. The mean of post-stroke quality of life domain was physical domain (45,27%), psychological domain (49,87%), social relations domain (48,15%) and environmental domain (50.01%). Objective: the purpose of the study was know the quality of life of the stroke patients in Outpatient Polyclinic of Private Hospital in Yogyakarta. Methods: used descriptive quantitative by using questionnaire test of purposive sampling system based on patients who have been affected of ischemic or hemorrhagic stroke before, number 30 respondents. Result: quality of life of stroke patient of medium physical dimension (67%), psychological dimension (71%), social dimension (67%), dimension good environment (63%). Conclusion: the quality of life of stroke patients of physical dimension, psychological dimension, and moderate social dimension, while the quality of life of stroke patients were good environmental dimension.   Keywords: Hemorrhagic stroke, ischemic stroke, quality of life

ANALYTICAL EPIDEMIOLOGY OF GASTRIC CANCER IN THE REPUBLIC OF CRIMEA AND ITS CONFORMITY WITH ALL-RUSSIAN TRENDS

2018 ◽  
Vol 64 (5) ◽  
pp. 592-601
Author(s):  
Viktor Oleksenko ◽  
Kazim Aliev ◽  
I. Akinshevich ◽  
Ye. Chirva
Keyword(s):  
Gastric Cancer ◽  
Epidemiological Data ◽  
Mortality Rates ◽  
Similar Data ◽  
Results Of Treatment ◽  
Mortality Index ◽  
World Standard ◽  
The Russian Federation ◽  
The Republic ◽  
National Trends

Gastric cancer (GC) is one of the most common malignant tumor, both world-wide and in the Russian Federation (RF), possessing one of the highest mortality rates. The aim of current research was to analyze the main epidemiological data, the rates reflecting the diagnostics and results of treatment of GC patients in the Republic of Crimea (RC) and to compare with national trends. Using the extensive, intensive, standardized rates, estimated by world standard method, structural analysis of the epidemiology of GC in RC for the period from 2007 to 2016 was carried out. The obtained results made it possible to compare these data with the main GC rates in RF. Results of the study. The incidence of GC in RC decreased during 10 years, for men - 16,42 (4th place), for women - 6,68 (9th place) per 100 000 of the population. By 2021 a further decline in morbidity in men is expected to be 30,27% and a possible increase in the female incidence rate - by 17,54%. The average age of GC patients in RC was 66,5 years. Index accuracy was 0,75, which testified to satisfactory conditions of specialized treatment for this tumor. Mortality from GC at the 1st year of life in RC was higher than in RF - 56,0%, which was due to low active diagnostics - 3,6% and accordingly a high proportion of GC patients of IV stage - 43,3%. Ratio index in RC for 10 years was higher than in RF and increased from 3,5 to 4,4; prevalence rate of GC in RC was lower - 84,1 per 100 000 of the population in comparison with RF, GC mortality index - 15,3 per 100 000 of the population that was lower than in RF. The proportion of patients who have been observed for 5 years or more in RC was 57,3% that was more than in RF. Conclusions. The rates reflecting early diagnostics of GC in RC are worse than all-Russian ones, which makes it necessary to develop medical examination program for the population of RC for this malignancy. The growth of ratio index, the lower mortality rates and the greater proportion of people who have been observed for 5 years or more indicates the best results of treatment of patients with GC in RC compared with similar data in RF.

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