scholarly journals On the problem of the relationship between arterial hypertension and coronavirus disease (COVID-19): literature review

HYPERTENSION ◽  
2021 ◽  
Vol 14 (4) ◽  
pp. 40-45
Author(s):  
S.M. Koval ◽  
O.V. Mysnychenko ◽  
M.Yu. Penkova

The literature review is devoted to the problem of the relationship between arterial hypertension and coronavirus disease (CVD; COVID-19), which has attracted attention from the very beginning of the pandemic of this infectious disease. The literature data, despite certain disagreements, indicate a higher incidence of CVD (COVID-19) among hypertensive patients, especially the elderly and patients with comorbid cardiovascular diseases, obesity, and diabetes mellitus. Besides, it has been shown that in these patients, CVD (COVID-19) has a more severe course. In this regard, these categories of patients need to provide effective treatment and prophylactic care and create conditions for the prevention of CVD (COVID-19) infection based on the modern European standards.

Author(s):  
Lorena Ciumărnean ◽  
Mircea Vasile Milaciu ◽  
Vasile Negrean ◽  
Olga Hilda Orășan ◽  
Stefan Cristian Vesa ◽  
...  

Cardiovascular diseases create an important burden on the public health systems, especially in the elderly, mostly because this group of patients frequently suffer from multiple comorbidities. Accumulating cardiovascular risk factors during their lifetime has a detrimental effect on an older adult‘s health status. The modifiable and non-modifiable cardiovascular risk factors are very diverse, and are frequently in a close relationship with the metabolic comorbidities of the elderly, mainly obesity and Diabetes Mellitus. In this review, we aim to present the most important cardiovascular risk factors which link aging and cardiovascular diseases, starting from the pathophysiological links between these factors and the aging process. Next, we will further review the main interconnections between obesity and Diabetes Mellitus and cardiovascular diseases of the elderly. Lastly, we consider the most important aspects related to prevention through lifestyle changes and physical activity on the occurrence of cardiovascular diseases in the elderly.


2019 ◽  
Vol 70 (7) ◽  
pp. 2415-2419 ◽  
Author(s):  
Valeria Carmen Albu ◽  
Raluca Elena Sandu ◽  
Andreea Lili Barbulescu ◽  
Elena-Anca Tartea ◽  
Emilia Burada ◽  
...  

The aim of the study was to assess the correlations between the acute confusing syndrome and different comorbidities found in a group of 126 elderly patients with this diagnosis, who were admitted to the Neurology Clinic of the Neuropsychiatry Hospital of Craiova. The main syndromes highlighted at the neurological examination were confusing, pyramidal and vestibular syndromes. The acute confusing syndrome has a multifactorial etiology, due to the wide range of comorbidities encountered in elderly patients. In our study the most frequent comorbidities were cardiovascular pathology, diabetes mellitus, dyslipidemia, cerebrovascular renal, hepatic pathology.


2018 ◽  
Vol 12 (5) ◽  
pp. 1303 ◽  
Author(s):  
Ludmilla Borges Santos ◽  
Wellington Luiz Lima ◽  
Josiane Maria Oliveira Souza ◽  
Marcia Cristina Da Silva Magro ◽  
Tayse Tâmara Paixão Duarte

RESUMOObjetivo: identificar os fatores associados ao risco de doenças cardiovasculares em usuários da atenção primária à saúde (APS) hipertensos. Método: estudo quantitativo e transversal realizado com 115 usuários hipertensos cadastrados em uma unidade básica de saúde (UBS). Os dados foram registrados em questionáriosemiestruturado. Realizou-se análise descritiva e inferencial (teste t de Student e regressão logística multivariada). Valores p < 0,05 foram considerados significativos. Resultados: houve predomínio do sexo feminino (67,8%), idosos (> 60 anos) (66,1%), em uso contínuo de diuréticos (65,2%). Ao estratificar os usuários da APS de acordo com o risco para doenças cardiovasculares, observou-se que a maioria apresentou risco elevado (59,1%), risco médio (26,1%) e baixo risco (14,8%). Estão associados ao maior risco de eventos cardiovasculares os hipertensos com diabetes mellitus (DM) (p = 0,000), infarto agudo do miocárdio (IAM) (p = 0,000), insuficiência cardíaca congestiva (ICC) (p = 0,000) e aqueles em uso de diuréticos (p = 0,001). Conclusão: usuários da APS hipertensos com DM, IAM, ICC e em uso de diuréticos evoluíram com maior risco de evento cardiovascular. Nesse contexto, faz-se necessário proporcionar uma assistência integrada e pautada na prevenção não apenas para minimizar a ocorrência de complicações, mas principalmente para prolongar qualitativamente a vida dos usuários da APS hipertensos. Descritores: Hipertensão; Doenças Cardiovasculares; Atenção Primária à Saúde; Fatores de Risco; Consulta de Enfermagem; Assistência à Saúde.ABSTRACTObjective: to identify the factors associated with risk for cardiovascular diseases in hypertensive primary health care (PHC) users. Method: quantitative and cross-sectional study conducted with 115 hypertensive users enrolled in a Brazilian primary health center (UBS). Data were recorded in a semi-structured questionnaire. A descriptive and inferential analysis was performed (Student’s t-test and multivariate logistic regression). P values < 0.05 were regarded as significant. Results: there was predominance of women (67.8%), the elderly (> 60 years) (66.1%), continuous users of diuretic drugs (65.2%). By stratifying PHC users according to the risk for cardiovascular diseases, we observed that the majority showed high risk (59.1%), medium risk (26.1%), and low risk (14.8%). Hypertensive patients with diabetes mellitus (DM) (p = 0.000), acute myocardial infarction (AMI) (p = 0.000), congestive heart failure (CHF) (p = 0.000), and those using diuretic drugs (p = 0,001) are associated with an increased risk for cardiovascular events. Conclusion: hypertensive patients with DM, AMI, CHF, and those using diuretic drugs evolved with a greater risk for a cardiovascular event. In this context, there is a need for providing an integrated and preventive care based on prevention not only to minimize the occurrence of complications, but mainly to extend the life of hypertensive PHC users on a qualitative basis. Descriptors: Hypertension; Cardiovascular Diseases; Primary Health Care; Risk Factors; Office Nursing; Delivery of Health Care.                                                       RESUMENObjetivo: identificar los factores asociados con el riesgo de enfermedades cardiovasculares en usuarios de la atención primaria de salud (APS) hipertensos. Método: estudio cuantitativo y transversal realizado con 115 usuarios hipertensos inscritos en un centro de salud primaria (UBS) brasileño. Los datos se registraron en un cuestionario semi-estructurado. Se realizó un análisis descriptivo e inferencial (prueba t de Student y regresión logística multivariable). Los valores p < 0,05 se consideraron significativos. Resultados: hubo predominio de mujeres (67,8%), ancianos (> 60 años) (66,1%), usuarios continuos de diuréticos (65,2%). Al estratificar a usuarios de la APS de acuerdo con el riesgo de enfermedades cardiovasculares, observamos que la mayoría mostraba alto riesgo (59,1%), medio riesgo (26,1%) y bajo riesgo (14,8%). Los pacientes hipertensos con diabetes mellitus (DM) (p = 0,000), infarto agudo de miocardio (IAM) (p = 0,000), insuficiencia cardíaca congestiva (ICC) (p = 0,000) y aquellos que usan diuréticos (p = 0,001) están asociados con un mayor riesgo de eventos cardiovasculares. Conclusión: pacientes hipertensos con DM, IAM, ICC y aquellos que usan diuréticos evolucionaron con un mayor riesgo de evento cardiovascular. En este contexto, existe la necesidad de proporcionar una atención integrada y preventiva basada en la prevención no solo para minimizar la aparición de complicaciones, sino principalmente para extender la vida de los usuarios de la APS hipertensos sobre una base cualitativa. Descriptores: Hipertensión; Enfermedades Cardiovasculares; Atención Primaria de Salud; Factores de Riesgo; Enfermería de Consulta; Prestación de Atención de Salud.


2016 ◽  
Vol 94 (4) ◽  
pp. 245-249
Author(s):  
A. Ya. Kravchenko ◽  
Anna A. Chernykh ◽  
A. V. Budnevsky

This review deals with variability of arterial pressure (VAP) as an adverse factor contributing to the development and progression of cardiovascular diseases and renal pathology. VAP has recently attracted much attention in connection with results of ASCOT (Anglo-Scandinavian Cardiac Outcomes Trial) showing that VAP is a risk factor of stroke and other complications of arterial hypertension (AH).The relationship between VAP and renal function remains unexplored and is considered to be a vicious circle in which kidneys are both a cause of AH and its target organs. Evidently, elucidation of the relationship between enhanced VAP and renal function is of primary importance.


2020 ◽  
Vol 38 (15_suppl) ◽  
pp. e17069-e17069
Author(s):  
Roman Osokin ◽  
Ekaterina Komarova ◽  
Igor Aboyan ◽  
Aleksey Yu. Maksimov ◽  
Roman Ischenko ◽  
...  

e17069 Background: In the last decade, the relationship between arterial hypertension and the risk of developing kidney cancer has been pointed out. Some studies have shown that the metabolic imbalance of the components of the renal renin-angiotensin system (RAS) is associated with the development and progression of kidney cancer. Aim: To study the state of RAS in tumor and peritumoral tissues in hypertensive patients with kidney cancer. Methods: In patients with localized kidney cancer T1N0M0 and grade I-II arterial hypertension without special treatment (n = 40; KC + AH) in the samples of tumor (TT), peritumoral (PTT) and histologically unchanged tissue (HUT), the levels of angiotensin 1 and 2, 1-7 (AT1 and AT2, AT (1-7)) of angiotensin-converting enzymes (ACE and ACE2) were determined by ELISA. The comparison group consisted of patients with RC without impaired blood pressure (n = 55, KC). Results: In patients with KC, the level of AT1 is 1.5 times higher (p < 0.05), and AT2 is 1.6 times higher (p < 0.05) in TT against the background of unchanged content in PTT compared with HUT. The level of ACE is higher than HUT by 2.7 times, ACE2 - by 1.6 times (in all cases p < 0.05), and in PTT it is identical in HUT. In patients with KC + AH, the level of AT1 and AT2 in the TT is 1.8 times higher (p < 0.05) and 2.1 times (p < 0.01), respectively, the content of AT(1-7) is 1.6 times (p < 0.01). In PTT, AT1 is 1.6 times higher (p < 0.01) and AT2 is 1.9 times higher (p < 0.05), significantly lower than only AT2 in the TT (1.2 times at p < 0, 05). The level of AT(1-7) in the PTT is identical to the values in the GNT. The content of ACE and ACE2 in TT is 3.6 and 2.9 times higher, respectively, and in PTT is identical to that in TT. Correlation analysis revealed a reliable direct relationship in the studied groups for all parameters, while in the PTT of hypertensive patients, the relationship between the average blood pressure and the RAS peptide content had a higher tightness. Conclusions: An increase in the levels of angiotensin 1 and 2, angiotensin-converting enzymes ACE and ACE2 in the tumor tissues and peritumoral tissue in patients with localized kidney cancer, regardless of the presence of arterial hypertension at initially higher values in hypertensive patients, was shown. The presence of arterial hypertension in patients with KC changes the metabolism of local RAS in peritumoral tissue and is associated with an increase in the correlation between changes in the components of RAS and arterial hypertension.


2015 ◽  
Vol 1084 ◽  
pp. 492-495
Author(s):  
Irina Yu. Efimova ◽  
Nataliya Yu. Efimova ◽  
Sergey V. Triss ◽  
Yuri B. Lishmanov

Article focuses on the use of 99mTc-HMPAO brain SPECT for evaluation of cerebral blood flow in patients with arterial hypertension and identification of the relationship of brain perfusion and cognitive function. Using SPECT of brain with 99mTc-HMPAO it was found out that hypertensive patients even in the absence of focal neurological symptoms have hypoperfusion of the brain which leads to cognitive dysfunction: decreased attention, psychomotor speed and slow thought processes.


2012 ◽  
Vol 29 (7) ◽  
pp. e55-e61 ◽  
Author(s):  
R. Schreiber ◽  
M. C. Ferreira-Sae ◽  
A. C. Tucunduva ◽  
J. G. Mill ◽  
Felipe O. Costa ◽  
...  

2021 ◽  
Vol 22 (3) ◽  
pp. 243-247
Author(s):  
Thalita Araújo dos Santos ◽  
Murilo Silva Alves ◽  
Thais Silva Pereira Campos ◽  
Mônica Pinchemel Nascimento

AbstractControl and the care are continuous challenges in the treatment of chronic diseases, and it is necessary to know the users’ realities in order to seek intervention alternatives. The study aimed to identify the participants’ knowledge in a therapeutic group of the elderly regarding diabetes mellitus and systemic arterial hypertension. Descriptive and exploratory study with a qualitative approach, conducted with 12 elderly in the therapeutic group. Semi-structured interviews were used as data collection technique. Data were transcribed and analyzed using the content analysis technique. In the results the category about the participants’ knowledge on the diseases emerged, namely: etiological factors; main signs, symptoms and complications; drug therapy; use of herbal medicines; food control; lifestyle and regular follow-up at the health unit. It was concluded that the participants have knowledge about the diseases; however, they cultivate habits that can trigger complications. Knowledge from experience should not be neglected, but should be directed towards achieving the goal of the therapeutic group, helping to improve the understanding of the elderly about their disease (s) and stimulating self-care.Keywords: Therapeutics. Health Education. Chronic Disease. Self-Care. ResumoO controle e o cuidado são desafios contínuos na terapêutica das doenças crônicas, sendo necessário conhecer as realidades dos usuários para buscar alternativas de intervenção. O estudo objetivou identificar o conhecimento dos participantes de um grupo terapêutico de idosos em relação ao diabetes mellitus e hipertensão arterial sistêmica. Estudo descritivo e exploratório, com abordagem qualitativa dos dados. A pesquisa foi realizada no munícipio de Itabuna na Bahia, na Unidade de Saúde da Família Simão Fitterman, no ano de 2014. Participaram do estudo 12 idosos do Sistema de Cadastramento e Acompanhamento de Hipertensos e Diabéticos (HIPERDIA), que participaram das reuniões do grupo terapêutico de idosos. A técnica utilizada para coleta de dados foi a entrevista com roteiro semiestruturado, realizadas nas reuniões do grupo terapêutico da unidade referida. O instrumento de coleta foi composto por dados sócio demográficos, conceitos e fatores desencadeantes das doenças estudadas, tratamento não farmacológico, complicações, prevenção e noções de autocuidado. Concluiu-se que os participantes possuem conhecimento sobre as doenças, entretanto cultivam hábitos que podem desencadear complicações. O conhecimento advindo da experiência, não deve ser negligenciado, mas direcionado ao alcance do objetivo do grupo terapêutico, contribuindo na melhoria do entendimento dos idosos sobre sua (s) doença (s), e estimulando o autocuidado.Palavras-chave: Terapêutica. Educação em Saúde. Doença Crônica. Autocuidado.


2019 ◽  
Vol 27 (2) ◽  
pp. 172-180 ◽  
Author(s):  
Daria V. Seliverstova

Aim. Identification of risk factors (RF) for myocardial infarction (MI) among women with preserved menstrual function. Material and Methods. 121 Female patients under 55 years of age, who were hospitalized with MI in the cardiology departments of Ryazan in the period 2010-2016, were studied. All patients were divided into 2 groups. The first group included women with a regular menstrual cycle without menopausal symptoms (n=60, mean age 48.0±6.1 years). The second group consisted of postmenopausal women (n=61, mean age 49.8±4.3 years). Of a cohort of studied  women a group of women was isolated (n=18 from group 1 and n=15 from group 2) who, during hospitalization with MI in 2015-2016, filled in questionnaires on nutrition and physical activity. Results. In women of group 1 such risk factors as burdened heredity for cardiovascular diseases (58.3%, p=0.02) and smoking (46.7%, p=0.03) were more common than in women of group 2. Only women of group 1 took oral contraceptives before the onset of MI (15%, p=0.005). The most common RFs were: arterial hypertension (˃80% of patients in both groups; overweight and obesity (78.3% of women from group 1 and 83.6% from group 2); type 2 diabetes mellitus  (23.3% in group 1 and 24.6% in group 2). According to the results of the questionnaire on food habits, insufficient use of fruit and vegetables was detected among all patients of both groups. In analysis of the results of the International Physical Activity Questionnaire (IPAQ), 72.2% of patients in group 1 experienced insufficient physical activity, and 53.3% of patients in group 2 showed pronounced hypodynamia. Biochemical analysis of blood revealed increased average levels of total cholesterol, low-density lipoproteins and triglycerides, with high-density lipoproteins within the normal range in both groups. Conclusion. The most common risk factors for myocardial infarction in women with preserved menstrual function in comparison with postmenopausal women were: positive heredity for cardiovascular diseases, smoking and taking oral contraceptives. Besides, a wide spread of arterial hypertension, dyslipidemia and diabetes mellitus, overweight and obesity, low physical activity and lack of fruit and vegetables in the diet of women in both groups should be noted.


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