IN VITRO STUDIES ON THE ANTIDIABETIC ACTIVITY OF 2-THIOHYDANTOIN USING α-amylase AND α-GLUCOSIDASE
2019 ◽
pp. 155-157
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Keyword(s):
Objective: The aim of the present study was to investigate the inhibitory effect of 2-thiohydantoin on the enzymes α-amylase and α-glucosidase in vitro as an antidiabetic therapeutic approach to reduce gastrointestinal glucose production. Methods: Antidiabetic activity of the compound, 2-thiohydantoin was measured using the enzymes α-amylase and α-glucosidase. Results: Half-maximal inhibitory concentration of the antidiabetic α-amylase was found to be 410.35 μg/ml and α-glucosidase was found to be 356.33 μg/ml, respectively. Conclusion: The result obtained in the in vitro enzyme assay suggests the antidiabetic activity of 2-thiohydantoin.
2021 ◽
Vol 11
(6-S)
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pp. 9-13
Keyword(s):
2003 ◽
Vol 304
(1)
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pp. 48-55
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Keyword(s):
2001 ◽
Vol 9
(4)
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pp. 239-244
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2020 ◽
Vol 10
(3)
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pp. 31-35