scholarly journals A Retrospective Study of Bacteriology and Antibiotic Sensitivity Pattern of Post Operative Surgical Site Infections in Orthopedics

2021 ◽  
Author(s):  
R. Rajani ◽  
J. Veerabhadra
Keyword(s):  
Retrospective Study ◽  
Antibiotic Sensitivity ◽  
Surgical Site Infections ◽  
Acinetobacter Species ◽  
Operative Morbidity ◽  
Antimicrobial Susceptibility Pattern ◽  
Sensitivity Pattern ◽  
Susceptibility Study ◽  
Global Estimates

Surgical Site Infection (SSI) is one of the most common post-operative complications and causes significant post-operative morbidity and mortality. The global estimates of SSI have varied from 0.5% to 15%, studies in India have consistently shown higher rates ranging from 23% to 38%1. The aim of the study was to know the etiological bacterial agents causing SSI and their antimicrobial susceptibility pattern. This retrospective study included 69 patients who developed Post-operative wound infections (SSI) during the 1-year period from April 2019 to March 2020. An analysis of SSI occurrence, the organisms isolated and antibiotic sensitivity pattern results was made. In overall surgeries conducted during the study period in orthopedics department at our institute, 69 cases were clinically diagnosed of having SSIs, including 51 males and 18 females with the mean age of 39.2 years. Out of the total 69 samples, 6 (8.69%) yielded no bacterial growth and among the rest 63 samples, Staphylococcus aureus 21(30.43%) was the most common organism isolated. The other organisms isolated were Klebsiella pneumonia13 (18.84%), Pseudomonas 11 (15.94%), Escherichia coli 5 (7.24%), Proteus species 3(4.34%) and Acinetobacter species 3(4.34%). Mixed isolates were obtained in 2(11.9%) specimens. Bacteriological and antibiotic susceptibility study is an important tool to treat infection timely and effectively in-turn minimizing untoward long term sequelae of surgical site infections.

scholarly journals Severity and long-term complications of surgical site infections after orthognathic surgery: a retrospective study

2020 ◽  
Vol 10 (1) ◽  
Author(s):  
Anne-Sabine Cousin ◽  
Pierre Bouletreau ◽  
Joris Giai ◽  
Badr Ibrahim ◽  
Aurélien Louvrier ◽  
...  
Keyword(s):  
Retrospective Study ◽  
Orthognathic Surgery ◽  
Surgical Site Infections

scholarly journals Clinico-etiological profile and antimicrobial susceptibility pattern of bacterial keratitis in the era of automated platforms

2021 ◽  
Vol 7 (1) ◽  
pp. 44-49
Author(s):  
Dr. Ranjana Rohilla ◽  
◽  
Dr. Aroop Mohanty ◽  
Dr. Suneeta Meena ◽  
Dr. Neelam Kaistha ◽  
...  
Keyword(s):  
Bacterial Culture ◽  
Antibiotic Sensitivity ◽  
Empirical Therapy ◽  
Resistance Pattern ◽  
Gram Negative Bacteria ◽  
Microbial Keratitis ◽  
Gram Positive ◽  
Antimicrobial Susceptibility Pattern ◽  
Sensitivity Pattern ◽  
A Prospective Study

Background: Microbial keratitis is one of the most significant causes of blindness in our country.Knowledge regarding the aetiology and antibiotic sensitivity pattern in a specific region is crucial forthe ideal management of these infections. Materials and Methods: A prospective study wherecorneal scrapings from 161 suspected cases of microbial keratitis were collected and were subjectedto direct microscopy by gram stain and bacterial culture and identification as well as antibioticsensitivity testing. Results: A total of 57 samples turned out to be positive out of the total 161 andwere shared equally by both gram-positive and gram-negative bacteria. All these culture-positivebacteria were also identified by MALDI TOF-MS and were speciated. Few rare organisms which couldnot be identified by conventional means were also recovered using the same. Most of the gram-positive isolates showed good sensitivity to vancomycin and ciprofloxacin whereas Pseudomonas sppwas found to be resistant to the aminoglycosides. Conclusion: Right knowledge about the localprofile of bacterial causes of keratitis along with its antibiotic resistance pattern will help theclinicians immensely and help them to initiate the correct empirical therapy bases on the smearresults without wasting crucial time.

scholarly journals Identification, Speciation and Antibiogram along with Detection of Metallo Beta-lactamase Production in Acinetobacter Isolated from Clinical Samples in a Tertiary Care Hospital

2021 ◽  
Author(s):  
N Ashwin Chitrabanu ◽  
Shrikara Mallya
Keyword(s):  
Acinetobacter Baumannii ◽  
Tertiary Care ◽  
Antibiotic Sensitivity ◽  
Clinical Samples ◽  
Care Hospital ◽  
Acinetobacter Species ◽  
Carbapenem Resistant ◽  
Appropriate Treatment ◽  
Sensitivity Pattern ◽  
Synergy Test

Acinetobacter species are gram negative non fermenters, which are important nosocomial pathogens involved in various outbreaks in hospitals due to widespread resistance to majority antibiotics. The aim of this study is to speciate Acinetobacter isolated from clinical samples, to assess the antibiotic sensitivity pattern and to detect the production of metallo-β-lactamase by double disc synergy test. The study was conducted in the department of microbiology, A. J Institute of Medical Sciences. All clinical samples were subjected to gram stain & cultured; the Acinetobacter isolates obtained were subjected to antibiogram. Those isolates that showed Imipenem resistant were further tested for production of metallo-β-lactamase by double disc synergy test. Out of 6625 culture positive isolates, 414 (36.1%) were identified biochemically to belong to Acinetobacter species. Of the 414 cases, 393 (94.9%) were further identified to be Acinetobacter baumannii and the remaining 21 (5.1%) to be Acinetobacter lwoffi. Acinetobacter lwoffii showed 100% sensitivity to all the drugs. Of the 393 Acinetobacter baumannii isolates 109 (27.7%) showed resistant to Imipenem. Out of these 109 isolates, 65 (59.63%) were positive for metallo-β-lactamase production by double disk synergy test. The speciation is highly demanding and laborious but it’s important to be demonstrated due to difference in the antibiotic susceptibility pattern. Carbapenem resistant Acinetobacter nosocomial strains in ICUs are detected to be more resistant to antibiotics. As shown in this study the metallo-β-lactamase producing A.baumannii isolates were 59.63% and therapeutic options were limited. Therefore early identification of metallo-β-lactamase producers is of great importance to start appropriate treatment and to control the spread.

scholarly journals STUDY OF BACTERIA ISOLATED FROM URINARY TRA INFECTION AND THEIR SENSITIVITY PATTERN

2004 ◽  
Vol 43 (154) ◽  
Author(s):  
Aarati Karki ◽  
B R Tiwari ◽  
S B Pradhan
Keyword(s):  
Staphylococcus Aureus ◽  
Retrospective Study ◽  
Nalidixic Acid ◽  
Urine Sample ◽  
Bacterial Species ◽  
Antibiotic Sensitivity ◽  
Klebsiella Species ◽  
E Coli ◽  
Sensitivity Pattern ◽  
Proteus Species

A retrospective study was conducted among out-patient and in-patient in Kathmandu medical collegeTeaching hospital of one month from the duration 2060-11-15 to 2060-12 -15. Mid-stream urine [MSU] of300 patient were cultured. Out of these, 75 patients’ urine were found to have significant bacterial growth.Total of five species of bacterial species isolated were viz.E.coli 37(33.3%), Proteus species 25(27.7%),Klebsiella species 15(16.6%), Staphylococcus aureus 8(8.8%) and Pseudomonas aureginosa 1(1.1%).Regarding their antibiotic sensitivity pattern, E. coli were sensitive to Nitrofurantoin 31 (83.8% ), Norfloxacin25 (67.5%), Ofloxacin 30(81.0%), Amoxycillin 16(43.2%), Nalidixic acid 15 (40.5%).proteus species weresensitive to Nitrofurantoin 15 (60.0%), Norfloxacin 15 (60.0%), Ofloxacin 12(48.0%), Amoxycillin 13(52.0%),Nalidixic acid 10 (40.0%), Ciprofloxacillin 12(48.0%). Klebsiella species were sensitive to Nitrofurantoin 9(60.0%), Norfloxacin 5 (33.3%), Oflaxin 6(40.0%), Amoxycillin 5(33.3%), Nalidixic acid 4 (26.6%),ciprofloxacillin 6(40.0%).Staphylloccus aureus were sensitive to Nitrofurantoin 8(100.0%), Norfloxacin 6(75.0%), Oflaxin 8(100.0%),Amoxycillin 7(87.5%), Nalidixic acid 6(75.0%), Ciprofloxacillin 8(100 %). And Pseudomonas aureginosawere resistant to all antibiotics which we are using in this research work.Key Words: Urine sample, Identification, Sensitivity pattern.

scholarly journals Surgical Site Infection, Bacterial Isolates and Their Sensitivity Pattern at Surgical Ward

2013 ◽  
Vol 11 (2) ◽  
pp. 18-20
Author(s):  
Sushila Devi Bhandari
Keyword(s):  
Surgical Site Infection ◽  
Antibiotic Sensitivity ◽  
Surgical Site Infections ◽  
Site Infection ◽  
First Line ◽  
Surgical Department ◽  
E Coli ◽  
Sensitivity Pattern ◽  
Surgical Ward ◽  
Selection Of

Introduction: Surgical site infection is a common occurrence in surgical ward. Knowledge about the commonest pathogen and its sensitivity in a particular setting is crucial in selection of appropriate antibiotics. No study has been performed earlier to identify the pattern of infection and antibiotic sensitivity in surgical department. So, this study aimed to analyze the commonest isolates from surgical site infection and their sensitivity pattern. Methods: A total of 56 cases of surgical site infection who were admitted in surgical ward at Shree Birendra Hospital, were included in this study. Wound swab from the infected surgical site was taken and send for culture and sensitivity. The obtained results were analysed using descriptive tools. Results: Among 56 surgical site infections only in 30 cases a pathogen was isolated. The commonest organism isolated was E.Coli 15(50%) followed by Staph. Aureus. The most sensitive antibiotics was Amikacine for E. Coli, and cefixime for S. Aureus. Conclusions: Ciprofloxacin seems to be the most appropriate first line oral antibiotics as it is sensitive both to E. Coli and S Aureus.Medical Journal of Shree Birendra Hospital; July-December 2012/vol.11/Issue2/18-20 DOI: http://dx.doi.org/10.3126/mjsbh.v11i2.7903  

scholarly journals ACINETOBACTER SPECIES

2018 ◽  
Vol 25 (12) ◽  
pp. 1949-1953
Author(s):  
Aneela Khawaja ◽  
Faiqa Arshad ◽  
Sadaf Aleem
Keyword(s):  
Tertiary Care ◽  
Antibiotic Sensitivity ◽  
Diffusion Method ◽  
Resistance Pattern ◽  
Biochemical Tests ◽  
Disk Diffusion Method ◽  
Acinetobacter Species ◽  
Clinical Specimens ◽  
Sensitivity Pattern ◽  
Acinetobacter Spp

Introduction: The genetic competencies of bacteria and the resistance have been impeding the usefulness of antibiotic therapy. There has been an alarming increase in the infections caused by Acinetobacter spp. especially the multidrug resistance pattern has narrowed the therapeutic ranges. Objectives: To determine the prevalence and antibiotic sensitivity pattern of Acinetobacter spp., among clinical specimens of tertiary care hospital.Study Design: Descriptive study. Place & Duration of Study: Pathology Department, PGMI, from January 2015 to December 2015. Materials & Methods: Total 8465 clinical specimens were inoculated. Acinetobacter spp. was identified and isolated by the preliminary microbiological and biochemical tests. Antimicrobial susceptibility testing was implemented by modified Kirby-Bauer disk diffusion method as per CLSI guidelines (2015). Results: Acinetobacter spp. isolated in 234 (7.29%) clinical specimens among 3208 (37.89%) culture positive isolates. Out of total 234 Acinetobacter spp. isolates 144 (61.54%) were recovered from male patients and 90 (38.46%) from female patients. the frequency of Acinetobacter spp. isolates was seen highest in CSF (23.07%) and lowest in HVS (5.52%) specimens. Maximum samples were recovered from surgical wards 85 (36.32%), while from pediatrics department only 20 (8.54%) samples. Only, 140 (59.82%) isolates were sensitive to tigecycline; while 216 isolates were (92.30%) resistant to salbactam. Conclusion: The progressively increasing threat of Acinetobacter resistant infections can be minimized by judicial use of antibiotics, and implementation of strict infection control policy in health care settings.

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