scholarly journals Guduchi is Powder Dosage Form is used in Treatment of Diabetics Mellitus

2021 ◽  
Vol 9 (12) ◽  
pp. 1385-1393
Author(s):  
Miss. Ghodake Rutuja Lakshman
Keyword(s):  
Diabetes Mellitus ◽  
Dosage Form ◽  
Oral Route ◽  
Dosage Forms ◽  
Present Review ◽  
Tinospora Cordifolia ◽  
Depth Information ◽  
Herbal Drugs ◽  
Safety And Efficacy

Abstract: Guduchi is one of the most versatile rejuvenating herb, possessing numerous therapeutic attributes. Madhumehahara (Antidiabetic) properties of Guduchi are highly appreciated in Ayurveda and even in recent modern researches. Scattered information pertaining to antidiabetic role of Tinospora is accessible inAyurvedic literature and there is need to assemble it. Present review Present review encompasses indepth information of antidiabetic potential of Guduchi and its various dosage forms from Ayurvedic view and to understand the possible mechanism of its action in combating the complex pathology of diabetes. Over the centuries, herbs have served as a major source of medicines for prevention and treatment of diseases including diabetes mellitus. These herbs are getting more importance around the globe and many studies have provided safety and efficacy of such herbal drugs in different condition. Guduchi Tinospora cordifolia is reported as highly potent -antidiabetic herb in and Guduchi Satva (GS) is popularly used to treat . In the present study, GS prepared from the stem of T. cordifolia was evaluated for hypoglycemic and Antidibetic. GS was powder dissolve in distilled water and administered to oral route of powder dosage form. Present review encompasses (i) in-depth information of antidiabetic potential of Guduchi and its various dosage forms from Ayurvedic view and (ii) to understand the possible mechanism of its action in combating the complex pathology of diabetes. Keyword: Diabetes Mellitus, Guduchi, Madhumeha, Tinospora cordifolia.

scholarly journals FAST DISSOLVING TABLETS: A REVIEW

2017 ◽  
Vol 9 (2) ◽  
pp. 8
Author(s):  
Ashish Masih ◽  
Amar Kumar ◽  
Shivam Singh ◽  
Ajay Kumar Tiwari
Keyword(s):  
Dosage Form ◽  
Pediatric Patients ◽  
Psychiatric Patients ◽  
Physical Stability ◽  
Transition Process ◽  
Oral Route ◽  
Dosage Forms ◽  
Oral Dosage ◽  
Release Time

Fast dissolving tablets emerge as one of the popular and widely accepted dosage forms, especially for pediatric patients because of incomplete development of the muscular and nervous system and a case of geriatric patients suffering from Parkinson’s disorder or hand tremors. Few solid dosage forms like capsules and tablets are present days facing the problems like difficulty in swallowing (dysphagia), resulting in many incidences of non-compliance and making the therapy ineffective. Oral dosage form and oral route are the most preferred route of administration for various drugs have limitations like first-pass metabolism, psychiatric patients, bedridden and uncooperative patients. FDTs are disintegrating or dissolve quickly in the saliva without a need of water. Fast dissolving tablets are designed to dissolve in saliva remarkably faster, within a few seconds (less than 60 seconds), and those are real fast-dissolving tablets. FDTs formulations contain super disintegrants to enhance the disintegration rate of a tablet in the buccal cavity. FDTs have advantages such as easy portability and manufacturing, accurate dosing, good chemical and physical stability and an ideal alternative for geriatric and pediatric patients. FDTs have disintegrated quickly, absorb faster so, in vitro drug release time improve and this property of drugs (dosage form) enhanced bioavailability. FDT formulations have the advantage of both conventional tablet formulation and liquid dosage form. There are several technologies that are conventional or patented based on spray drying, cotton candy process, sublimation, melt granulation, direct compression freezes drying/lyophilization, phase transition process, mass extrusion, etc. have been developed for manufacturing of FDTs. In this review contain brief information about FDTs including definition, advantages, needs or requirements of FDTs, salient features of FDTs, limitations, challenges to developing FDT, marketed formulations of fast dissolving tablets, etc.

PHYSICO CHEMICAL EVALUATION OF AVIPATTIKARA CHURNA AND ITS DEVELOPED FORM OF SYRUP

INDIAN DRUGS ◽  
2015 ◽  
Vol 52 (06) ◽  
pp. 38-42
Author(s):  
G.G. Gadad ◽  
◽  
K. S. Gudaganatti ◽  
V.S. Mannur
Keyword(s):  
Dosage Form ◽  
Oral Route ◽  
Physicochemical Analysis ◽  
Dosage Forms ◽  
Solid Dosage ◽  
Chemical Evaluation ◽  
Physico Chemical ◽  
Limit Test ◽  
Loss Of Appetite ◽  
Liquid Dosage Form

Development and modification of Ayurvedic classical formulations into widely acceptable dosage forms is an important area to be focused in the present era. The designing of liquid dosage form has generally been emphasized on the basis of ease of administration to those individuals who have difficulty in swallowing solid dosage forms, specially in pediatric and geriatric group. Churna (powders) are the preferentially administered Ayurvedic formulations by oral route. Most of these powders are hygroscopic, bitter to taste and should be administered with suitable vehicle. Avipattikara Churna is one of the unique formulation widely practiced in the management of common ailments like Amlapitta (hyperacidity), Vibandha (constipation), Agnimandya (loss of appetite), Arsha (hemorrhoids). Modification of the classical Churna (solid dosage form) into a more acceptable and convenient syrup (liquid dosage form) with modern pharmaceutical methods and its physico-chemical analysis is the main aim of the study. In the present study Avipattikara syrup was developed with 66.7 % w/V of Khandasharkara (sugar candy powder) without any pharmaceutical additives. Physicochemical analysis, microbial limit test, and physical quality tests for Avipattikara Churna and syrup were carried out respectively. Results suggest that, the developed syrup had a quality of ideal syrup.

A Critical Review on multifold potentiality of Prakshepa Dravyas in Ayurvedic dosage forms

2017 ◽  
Vol 2 (4) ◽  
Author(s):  
Meghana Ashwath ◽  
Srinivas Yadav ◽  
Surekha Medikeri ◽  
Shobha G. Hiremath
Keyword(s):  
Critical Review ◽  
Dosage Form ◽  
Practical Knowledge ◽  
Pharmacological Action ◽  
Dosage Forms ◽  
Present Review ◽  
Patient Acceptability ◽  
Good Taste ◽  
Healing Power ◽  
Pharmaceutical Processing

The dosage forms in Ayurveda are given utmost importance. Our Acharyas offer a treasure of practical knowledge on the preparation of medicines and emphasized that the Samyoga (combination) of many drugs in a formulation greatly influence the healing power. One such category of drugs which are added in small quantities other than the main drugs so as to expand the field of activity of the main drugs are labelled as Prakshepa Dravyas. These Dravyas are distinctive to each Kalpana (dosage form). Although there are few drugs which are used as Prakshepa Dravyas irrespective of the dosage forms such as Madhu, Sita, Guda, Trikatu, Chaturjata, Taila, Ghrita, Lavana, Hingu, Kshara, Jeeraka, Shilajatu and Bhasmas of few metals. Prakshepa Dravyas can be considered as additives of modern pharmaceutical science which are limited only to pharmaceutical processing. Prakshepa Dravya acts as a synergizer and also attributes to the pharmacological action. They boost the patient acceptability by providing good taste, fragrance and appearance. The antioxidant and preservative properties are inherent in them. They also promote and augment the absorption of the drug by their bioenhancing activity. The present review aims to provide the comprehensive summary of Prakshepa Dravyas and also illustrates their multi dimensional activity.

scholarly journals Lysosomotropic Features and Autophagy Modulators among Medical Drugs: Evaluation of Their Role in Pathologies

Molecules ◽  
2020 ◽  
Vol 25 (21) ◽  
pp. 5052
Author(s):  
Tatiana A. Korolenko ◽  
Thomas P. Johnston ◽  
Vaclav Vetvicka
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Clinical Medicine ◽  
Current Knowledge ◽  
Present Review ◽  
Cellular Biochemistry ◽  
Biochemical Pharmacology

The concept of lysosomotropic agents significantly changed numerous aspects of cellular biochemistry, biochemical pharmacology, and clinical medicine. In the present review, we focused on numerous low-molecular and high-molecular lipophilic basic compounds and on the role of lipophagy and autophagy in experimental and clinical medicine. Attention was primarily focused on the most promising agents acting as autophagy inducers, which offer a new window for treatment and/or prophylaxis of various diseases, including type 2 diabetes mellitus, Parkinson’s disease, and atherosclerosis. The present review summarizes current knowledge on the lysosomotropic features of medical drugs, as well as autophagy inducers, and their role in pathological processes.

scholarly journals A COMPLETE AND UPDATED REVIEW ON VARIOUS TYPES OF DRUG DELIVERY SYSTEMS

2020 ◽  
pp. 1-16
Author(s):  
RAJEEV GARG ◽  
SHARANPREET KAUR ◽  
RITIKA ◽  
SHEHNAZ KHATOON ◽  
NAINA ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Drug Delivery Systems ◽  
Dosage Form ◽  
Research Area ◽  
Dosage Forms ◽  
Delivery Systems ◽  
The World ◽  
Different Types

The World of medicine has gained considerable interest in the research area all over the World. Scientists constantly work on the three parameters ‘Quality, Safety, Efficacy’ of a pharmaceutical ingredient. Refine these parameters; they are continually developing different dosage forms. These unique types of dosage forms help to provide improved bioavailability and efficacy of a pharmaceutical ingredient. The role of dosage form is to improve the availability of the medicine to treat the symptoms and disease. This article focus on the different types of dosage forms, their advantages and some important facts related to that dosage forms.

scholarly journals REVIEW: FAST DISSOLVING TABLET

2018 ◽  
Vol 10 (2) ◽  
pp. 5
Author(s):  
Aher Smita S. ◽  
Saudagar R. B. ◽  
Shinde Mayuri S.
Keyword(s):  
Dosage Form ◽  
Geriatric Patients ◽  
Oral Route ◽  
Dosage Forms ◽  
Oral Dosage ◽  
Solid Dosage Forms ◽  
Solid Dosage ◽  
Tablet Disintegration ◽  
Physical And Chemical ◽  
Pass Metabolism

Fast dissolving tablets is one of the most widely accepted dosage forms and also most popular dosage form, especially for pediatric patients because of incomplete development of the muscular and nervous system and a case of geriatric patients suffering from Parkinson’s disorder or hand tremors. Some solid dosage forms like tablets and capsules are present days facing the problems like difficulty in swallowing (dysphagia), resulting in many incidences of non-compliance and making the therapy ineffective. Oral dosage form and oral route are the most preferred route of administration for various drugs have limitations like the first-pass metabolism. Fast dissolving tablets are one of them. FDT have benefits such as accurate dosing, easy portability and manufacturing, good physical and chemical stability and an ideal alternative for pediatric and geriatric patients. Some tablets are designed to dissolve fastly in saliva, within a few seconds, and are true fast-dissolving tablets. Others contain agents to enhance the rate of tablet disintegration in the oral cavity and are more appropriately termed fast-disintegrating tablets, as they may take up to a minute to completely disintegrate.

A Comprehensive Review on Pellets as a Dosage Form in Pharmaceuticals

2021 ◽  
Vol 22 ◽  
Author(s):  
Shailesh Thirumaleshwar ◽  
Maithri Shanbhogue H. ◽  
Gowrav Mysore Prakash ◽  
Hemanth Kumar Somareddy ◽  
Gangadharappa Hosahalli Veerabhadrappa
Keyword(s):  
Drug Delivery ◽  
Gastrointestinal Tract ◽  
Sustained Release ◽  
Patient Compliance ◽  
Single Unit ◽  
Dosage Form ◽  
Oral Route ◽  
Dosage Forms ◽  
Comprehensive Review ◽  
Pellet Formation

Abstract: Oral route of administration is widely accepted and desired because of its versatility, convenience, and most importantly patient compliance. Multiparticulate systems like granules and pellets are more advantageous when compared to single-unit dosage forms, as they are capable to distribute the drug more evenly in the gastrointestinal tract. The current paper focuses on pellets, the merits and demerits associated, various pelletization techniques, and its characterization. It also focuses on how pellets can be employed for drug delivery in controlled and sustained release formulations. It gives a com-plete emphasis on the drug and excipients that can be used in pellet formation, the marketed formulations, and the research pertaining to pellets.

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