scholarly journals Evaluation of hair growth promoting activity of petroleum ether extract of Abrus precatorius Linn. on Wistar Albino rats

2019 ◽  
Vol 9 (2) ◽  
pp. 330-335
Author(s):  
Namrata Omhare ◽  
Pratibha Sahu ◽  
Shailee Gautam ◽  
Nidhi Jain
Keyword(s):  
Petroleum Ether ◽  
Hair Growth ◽  
Petroleum Ether Extract ◽  
Hair Follicles ◽  
Ether Extract ◽  
Standard Drug ◽  
Abrus Precatorius ◽  
Growth Initiation ◽  
Growth Promoting ◽  
Bald Patch

In present investigation was carried out to screening of hair growth promoting potentiality of petroleum ether extract of Abrus precatorius leaf. Preliminary chemical tests and TLC analysis revealed the presence flavonoids and saponins. Hair growth promoting activity of petroleum ether of Abrus precatorius was screened by considering different parameters which included time taken for covering bald patch, length of hair produced, percentage of hair follicles in anagen and telogen phases, time of hair growth initiation and completion and level of minerals in blood. The petroleum ether extract of Abrus precatorius showed a very good hair growth promoting activity at a dose of 300 mg/kg which was comparable to that of 2% minoxidil. After 30 days of treatment with test and standard drugs it was observed that, time taken for covering the bald patch, hair growth initiation and completion time and quantitative hair growth were found to be comparable to that of the standard drug. An increase in percentage of hair follicles turning from telogen phase to anagen phase was noted. The control treated group of animals showed poor hair growth for all the parameters. Keywords: Abrus precatorius Linn, Anagen, Catagen, Telogen, Minoxidil

scholarly journals Evaluation of Hair Growth Promoting Activity of Maharanga bicolor and Hibiscus rosa sinensis

2019 ◽  
Vol 5 (1) ◽  
pp. 34-38
Author(s):  
Kishor Adhikari ◽  
Laxman Wagle ◽  
Pramod Dhakal ◽  
Sanjaya Dhungana ◽  
Sujan Baral ◽  
...  
Keyword(s):  
Petroleum Ether ◽  
Hair Growth ◽  
Growth Promotion ◽  
Petroleum Ether Extract ◽  
Aloe Vera ◽  
Ether Extract ◽  
Hibiscus Rosa Sinensis ◽  
Aloe Vera Gel ◽  
Growth Initiation ◽  
Growth Promoting

Alopecia is common and most frequently complaint dermatological disorder since the time immemorial. Various herbal and allopathic formulations are reported to have hair growth promoting activity. Minoxidil and Finasteride are only US FDA approved drugs for alopecia and hair loss. Maharanga bicolor and Hibiscus rosa sinensis are two ethnomedicinal herbs commonly used for hair growth promotion. Present study was conducted to determine hair growth promoting activity of petroleum ether extract of M. bicolor and H. rosa sinensis in Aloe vera gel. Minoxidil Sulphate and Different formulations of petroleum ether extract of M. bicolor and H. rosa sinensis was formulated in Aloe vera gel and applied to denuated area of rats for 30 days. Hair growth pattern, hair growth initiation, hair growth completion and length of hair was measured. M. bicolor (2%) formulation shows shortest hair growth initiation time on 6th day compared to 11th day in blank sample. Formulation containing 2% of each extract have shortest hair growth completion time on 19th day of sample application and showed potent hair growth pattern observed by blind investigation. The result suggests that petroleum ether extract of M. bicolor and H. rosa sinensis possess good hair growth promoting activity. Key words: Maharanga bicolor, Hibiscus rosa sinensis, Hair growth promotion, Activity

scholarly journals PHARMACOLOGICAL ASSESSMENT OF ANTIULCER ACTIVITY OF GLORIOSA SUPERBA LINN TUBERS IN EXPERIMENTALLY INDUCED GASTRIC ULCERS

2021 ◽  
Vol 10 (3) ◽  
pp. 2852-2856
Author(s):  
Vaibhav P Uplanchiwar
Keyword(s):  
Lipid Peroxidation ◽  
Petroleum Ether ◽  
Petroleum Ether Extract ◽  
Radical Scavenging ◽  
Gastric Ulcers ◽  
Antiulcer Activity ◽  
Ether Extract ◽  
Protective Activity ◽  
Gloriosa Superba ◽  
Standard Drug

In a study, the potential of hydroalcoholic and petroleum ether extract of Gloriosa superba Linn (GS) tubers in the mitigation of antisecretory and antiulcer was studied. Both extracts were tested at 100, 200, and 400 mg/kg/p.o. using ethanol, and cold stress as toxicants. Both the extracts showed significant ulcer protection at the highest dose of 400mg/kg as compared to standard drug lansoprazole. To support its antiulcer potential, the plant was examined for radical - scavenging capability by lipid peroxidation. The extracts showed a comparative significant result. The flavonoids & polyphenols in the extracts verify the antioxidant potential. From the results, it was concluded that both hydroalcoholic and petroleum ether extracts of tubers of Gloriosa superba are having gastric ulcer protective activity.

Study on Phytoconstituents and Antimicrobial Potential of Sapindus mukorossi Fruit Extract

2020 ◽  
Vol 1 (28) ◽  
pp. 12-19
Author(s):  
Versha parcha ◽  
Keyword(s):  
Petroleum Ether ◽  
Petroleum Ether Extract ◽  
Ether Extract ◽  
Zone Of Inhibition ◽  
Fruit Extract ◽  
Standard Drug ◽  
Antimicrobial Potential ◽  
Medicinal Value ◽  
Phytochemical Investigation ◽  
Tumour Cell Growth

Sapindus mukorossiis well known for its folk medicinal values. The fruit is valued for the saponins (10.1%) present in the pericarp which constitutes up to 56.5% of the drupe known for inhibiting tumour cell growth. Recently many of the pharmacological actions of this plant have been explored which include the antimicrobial molluscicidal and insecticidal actions.Thefruitsareofconsiderableimportancefor their medicinal value for treatingseveraldiseaseslikeexcessivesalivation,pimples,epilepsy,chlorosis,migranes, eczemaand psoriasis etc.The powdered seeds are employed in the treatment ofdentalcaries, arthritis,commoncold, constipation and nausea. Keeping in view the medicinal importance of the fruit, it was thought worthwhile to carry out systematic study on phytochemical investigation and antimicrobial potential of fruit extract of Sapindus mukorossi.Fruit were dried, powdered and extracted with differentsolventsystemswithincreasingpolarity. The extracts were screened for the antibacterialandantifungalactivity.Predominance of antibacterial activity was observed at dose level of 50μg/ml of petroleum ether extract. Maximum zone of inhibition (19mm)&(18mm)wasobservedagainstSalmonellatyphiiand Shigelladysenteriarespectively as compared to standard drug Ampicillin20μg/ml.Sinceantibacterialactivity was observed in 50μg/ml concentration of petroleum ether extract, it was chosen forexploringitsantifungalpotentialalso.Maximum zone of inhibition was observed against Aspergillus sulfurous as compared to standard drug ketoconazole 20μg/ml. From the above study, it could be concluded that Sapindus mukorossipetroleum ether fruit extracts(50μg/ml) have good antimicrobial potential and can be explored further to isolate active principlesfrom the same.

Antioxidant lignans from petroleum ether extract of Schisandra chinensis

Planta Medica ◽  
2008 ◽  
Vol 74 (09) ◽  
Author(s):  
J Slanina ◽  
L Bøezinová ◽  
H Paulová ◽  
O Humpa
Keyword(s):  
Petroleum Ether ◽  
Petroleum Ether Extract ◽  
Schisandra Chinensis ◽  
Ether Extract

The struggle with rheumatism through Dracunculus vulgaris Schott: In the light of ethnobotanical information.

2020 ◽  
Vol 13 ◽  
Author(s):  
Fatma Tuğçe Gürağaç Dereli ◽  
Mert Ilhan ◽  
Esra Küpeli Akkol
Keyword(s):  
Petroleum Ether ◽  
Inflammatory Diseases ◽  
Petroleum Ether Extract ◽  
Major Constituent ◽  
Control Group ◽  
Ether Extract ◽  
Test Models ◽  
Mouse Ear ◽  
Gas Chromatography Mass Spectroscopy ◽  
Abdominal Constriction

Background: The fruits with the seeds of Dracunculus vulgaris Schott. (Araceae) are used against inflammatory diseases in Turkey. Objective: Present study was designed to justify this folkloric usage type of the plant. Therefore, the aim of this study is to investigate the anti-inflammatory activity of D. vulgaris. Methods: Petroleum ether, ethyl acetate and methanol extracts were prepared from the fruits, successively. Carrageenan-, serotonin-, and prostaglandin E2-induced hind paw edema; acetic acid–induced capillary permeability and 12-O-tetradecanoyl-phorbol-13-acetate–induced mouse ear edema models were used to assess the antiinflammatory activity of the extracts. The analgesic activity was experienced by using p-benzoquinone-induced abdominal constriction test. Results: The petroleum ether extract displayed the highest activities in all of the used test models compared with the control group. Therefore, the constituents of this extract were determined by using gas chromatography–mass spectroscopy (GC–MS). Linoleic acid was found to be major constituent of the petroleum ether extract of D. vulgaris. Conclusion: This study has provided some justification for the folkloric use of the plant.

scholarly journals The petroleum ether extraction of Brassica Rapa L. induces apoptosis of Lung adenocarcinoma cells via mitochondria-dependent pathway

2021 ◽  
Author(s):  
Xierenguli Halike ◽  
Jin-Yu Li ◽  
Pengfei Yuan ◽  
Kaimeiliya Yasheng ◽  
Min Chen ◽  
...  
Keyword(s):  
Petroleum Ether ◽  
Brassica Rapa ◽  
Biological Activities ◽  
Petroleum Ether Extract ◽  
Traditional Food ◽  
Ether Extract ◽  
Ether Extraction ◽  
Adenocarcinoma Cells ◽  
Lung Adenocarcinoma Cells ◽  
Dependent Pathway

Brassica rapa L. is one of the most popular traditional food with a variety of biological activities. In this study, the petroleum ether extract of B. rapa was separated by...

Identification of phytoconstituents of Tragia involucrata leaf extracts and evaluate their correlation with anti-inflammatory & antioxidant properties

2021 ◽  
Vol 20 ◽  
Author(s):  
Vinodhini Velu ◽  
Swagata Banerjee ◽  
Vidya Rajendran ◽  
Gaurav Gupta ◽  
Dinesh Kumar Chellappan ◽  
...  
Keyword(s):  
Antioxidant Activity ◽  
Ethyl Acetate ◽  
Petroleum Ether ◽  
Ethyl Acetate Extract ◽  
Petroleum Ether Extract ◽  
Inflammatory Activity ◽  
Ether Extract ◽  
Membrane Stabilization ◽  
Leaf Extracts ◽  
Anti Inflammatory

Aims: The present investigation was aimed at exploring the phytoconstituents using Gas Chromatography Mass Spectroscopy and to evaluate antioxidant and anti-inflammatory properties of the leaf extracts. Materials and Methods: The extracts were obtained sequentially with petroleum ether, ethyl acetate and water using soxhlet apparatus. The anti-inflammatory property of the identified compounds using GC- MS spectroscopy was evaluated in silico. The antioxidant activity was performed by DPPH and H2O2 method whereas anti-inflammatory study was carried out by HRBC membrane stabilization method. Terpenoids were found to be major constituents in petroleum ether extract while, phenols and flavonoids were predominantly found in ethyl acetate extract. Results and Discussion: The GC-MS analysis of the extract revealed six major molecules including Squalene, 19β, 28- epoxyleanan-3-ol and 2-tu-Butyl-5-chloromethyl-3-methyl-4-oxoimidazolidine-1-carboxylic acid. The ethyl acetate extract showed a significant antioxidant activity (P<0.01) in both DPPH method (70.87 %) and H2O2 method (73.58%) at 200 µg mL-1 . Increased membrane stabilization of petroleum ether extract was observed in the in vitro anti-inflammatory activity study. A strong relationship between the terpenoid content and anti-inflammatory activity was obtained from the correlation (0.971) and docking study. Conclusion: These results justify T. involucrata to be a rich source of terpenoids with potent antiinflammatory property.

scholarly journals Termite-Repellent Activity and Chemical Composition of West Indian Mahogany Wood, (Swietenia Mahagoni Jacq.) with Special Reference to the P2 Fraction

1969 ◽  
Vol 42 (3) ◽  
pp. 185-195
Author(s):  
Conrado F. Asenjo ◽  
Luis Amorós Marín ◽  
Wanda Torres ◽  
Alice Del Campillo
Keyword(s):  
Petroleum Ether ◽  
Petroleum Ether Extract ◽  
West Indian ◽  
Repellent Activity ◽  
Structural Level ◽  
Ether Extract ◽  
Selective Solvents ◽  
Ether Extraction ◽  
Termite Attack ◽  
Waxy Substance

1. Serial extraction of West Indian mahogany wood with selective solvents was performed. 2. The petroleum ether extract was the only fraction to exhibit promising termite-repellent activity. 3. Mahogany blocks subjected to petroleum ether extraction became susceptible to termite attack. 4. A waxy substance (P2 fraction) separated from the petroleum ether extract at times showed high termite-repellent activity. The termite-repellent principle in the P2 fraction seems to be a labile one, as the termite-repellent activity varied greatly from batch to batch. 5. The P2 fraction is a mixture of two major components and of at least a third minor one. As far as we have been able to determine this mixture, at the elemental level, contains carbon, hydrogen, and oxygen only, while esters have been the only compounds definitely characterized at the structural level.

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