scholarly journals The petroleum ether extraction of Brassica Rapa L. induces apoptosis of Lung adenocarcinoma cells via mitochondria-dependent pathway

2021 ◽  
Author(s):  
Xierenguli Halike ◽  
Jin-Yu Li ◽  
Pengfei Yuan ◽  
Kaimeiliya Yasheng ◽  
Min Chen ◽  
...  
Keyword(s):  
Petroleum Ether ◽  
Brassica Rapa ◽  
Biological Activities ◽  
Petroleum Ether Extract ◽  
Traditional Food ◽  
Ether Extract ◽  
Ether Extraction ◽  
Adenocarcinoma Cells ◽  
Lung Adenocarcinoma Cells ◽  
Dependent Pathway

Brassica rapa L. is one of the most popular traditional food with a variety of biological activities. In this study, the petroleum ether extract of B. rapa was separated by...

scholarly journals Termite-Repellent Activity and Chemical Composition of West Indian Mahogany Wood, (Swietenia Mahagoni Jacq.) with Special Reference to the P2 Fraction

1969 ◽  
Vol 42 (3) ◽  
pp. 185-195
Author(s):  
Conrado F. Asenjo ◽  
Luis Amorós Marín ◽  
Wanda Torres ◽  
Alice Del Campillo
Keyword(s):  
Petroleum Ether ◽  
Petroleum Ether Extract ◽  
West Indian ◽  
Repellent Activity ◽  
Structural Level ◽  
Ether Extract ◽  
Selective Solvents ◽  
Ether Extraction ◽  
Termite Attack ◽  
Waxy Substance

1. Serial extraction of West Indian mahogany wood with selective solvents was performed. 2. The petroleum ether extract was the only fraction to exhibit promising termite-repellent activity. 3. Mahogany blocks subjected to petroleum ether extraction became susceptible to termite attack. 4. A waxy substance (P2 fraction) separated from the petroleum ether extract at times showed high termite-repellent activity. The termite-repellent principle in the P2 fraction seems to be a labile one, as the termite-repellent activity varied greatly from batch to batch. 5. The P2 fraction is a mixture of two major components and of at least a third minor one. As far as we have been able to determine this mixture, at the elemental level, contains carbon, hydrogen, and oxygen only, while esters have been the only compounds definitely characterized at the structural level.

scholarly journals Phytochemical analysis of successive extracts of the Cordia macleodii leaves Hook.: A Folklore medicinal plant

2018 ◽  
Vol 4 (1) ◽  
pp. 14-17
Author(s):  
Gamit Rakesh ◽  
◽  
Patel Amit G ◽  
VJ Shukla ◽  
MB Nariya ◽  
...  
Keyword(s):  
Petroleum Ether ◽  
Uv Light ◽  
Biological Activities ◽  
Petroleum Ether Extract ◽  
Fluorescence Analysis ◽  
Phytochemical Analysis ◽  
Unsaponifiable Fraction ◽  
Ether Extract ◽  
Chemical Reagents ◽  
Chloroform Methanol

‘Preliminary phytochemical analysis of successive extracts, fluorescence analysis and HPTLC of C. macleodiileaves has been planned in the current study.’ The extracts of the dried coarse powdered of C. macleodii leaves obtained using different polarities solventsin succession were tested for the presence of various active phytoconstituents. Fluorescence analysis was investigated andunsaponifiable fraction of petroleum ether extract was also observed forchromatographic evaluations. The outcome suggest that the existence of various dynamic phytoconstituents having particular solubility in selected solvents of different polarities used in succession. The fluorescent analysis under the visible and UV light by treatment of diverse chemical reagents showed diverse colours. HPTLC profile of unsaponifiable fraction showed 10 and 3 spots at 254 nm and 366 nm radiation respectively. After spraying with diluted H2SO4, it showed 5 and 6 spots at 254 nm and 366 nm radiations respectively. The presence of active constituents in different polarities solvent, which were used in progression suggesting the significance of the solvent as a conclusive factor. Further the data suggests that, the successive extractions using Petroleum ether, chloroform, methanol and water solvents of different polarities would maximize the exploitation of the diverse bioactive compounds. Study concluded that it would be help to isolate and characterize the different pharmacologically dynamic principles of the C. macleodii such as mouth sores, treating jaundice, hepatoprotective and also as an aphrodisiac. It shows their importance for supporting their claimed uses and biological activities such as wound healing.

scholarly journals In vitro Phytochemical Investigation of Helianthus annuus Seeds

2016 ◽  
Vol 19 (1) ◽  
pp. 100-105 ◽  
Author(s):  
Rubab Tarannum Islam ◽  
Mir Monir Hossain ◽  
Kishor Majumder ◽  
Amjad Hossain Tipu
Keyword(s):  
Petroleum Ether ◽  
Helianthus Annuus ◽  
Biological Activities ◽  
Petroleum Ether Extract ◽  
Radical Scavenging ◽  
High Sensitivity ◽  
Chemical Components ◽  
Phytochemical Analysis ◽  
Ether Extract

The seeds of Helianthus annuus have been investigated for the presence of various chemical components and biological activities with special emphasis to the anti-oxidant, antimicrobial, cytotoxic and thrombolytic assay. The results of standard phytochemical analysis revealed the presence of tannins, saponins, flavonoids, carbohydrates, steroids, fixed oils and vitamins. In vitro antioxidant activity of methanolic seed extract of H. annuus was determined by DPPH free radical scavenging assay, which demonstrated very significant antioxidant potential compared to standard antioxidant (ascorbic acid). In case of antimicrobial assay, the methanolic and ethyl acetate extract of H. annuus seeds showed high sensitivity to Salmonella typhi and moderate sensitivity to Pseudomonous aeuregenosa. The petroleum ether extract revealed high sensitivity to P. aeuregenosa. The methanolic extract of H. annuus displayed LC50 1.2 ug/ml and its petroleum ether extract showed LC50 of 1.1 ug/ml, which indicated significant cytotoxicity.Bangladesh Pharmaceutical Journal 19(1): 100-105, 2016

Antioxidant lignans from petroleum ether extract of Schisandra chinensis

Planta Medica ◽  
2008 ◽  
Vol 74 (09) ◽  
Author(s):  
J Slanina ◽  
L Bøezinová ◽  
H Paulová ◽  
O Humpa
Keyword(s):  
Petroleum Ether ◽  
Petroleum Ether Extract ◽  
Schisandra Chinensis ◽  
Ether Extract

The struggle with rheumatism through Dracunculus vulgaris Schott: In the light of ethnobotanical information.

2020 ◽  
Vol 13 ◽  
Author(s):  
Fatma Tuğçe Gürağaç Dereli ◽  
Mert Ilhan ◽  
Esra Küpeli Akkol
Keyword(s):  
Petroleum Ether ◽  
Inflammatory Diseases ◽  
Petroleum Ether Extract ◽  
Major Constituent ◽  
Control Group ◽  
Ether Extract ◽  
Test Models ◽  
Mouse Ear ◽  
Gas Chromatography Mass Spectroscopy ◽  
Abdominal Constriction

Background: The fruits with the seeds of Dracunculus vulgaris Schott. (Araceae) are used against inflammatory diseases in Turkey. Objective: Present study was designed to justify this folkloric usage type of the plant. Therefore, the aim of this study is to investigate the anti-inflammatory activity of D. vulgaris. Methods: Petroleum ether, ethyl acetate and methanol extracts were prepared from the fruits, successively. Carrageenan-, serotonin-, and prostaglandin E2-induced hind paw edema; acetic acid–induced capillary permeability and 12-O-tetradecanoyl-phorbol-13-acetate–induced mouse ear edema models were used to assess the antiinflammatory activity of the extracts. The analgesic activity was experienced by using p-benzoquinone-induced abdominal constriction test. Results: The petroleum ether extract displayed the highest activities in all of the used test models compared with the control group. Therefore, the constituents of this extract were determined by using gas chromatography–mass spectroscopy (GC–MS). Linoleic acid was found to be major constituent of the petroleum ether extract of D. vulgaris. Conclusion: This study has provided some justification for the folkloric use of the plant.

Identification of phytoconstituents of Tragia involucrata leaf extracts and evaluate their correlation with anti-inflammatory & antioxidant properties

2021 ◽  
Vol 20 ◽  
Author(s):  
Vinodhini Velu ◽  
Swagata Banerjee ◽  
Vidya Rajendran ◽  
Gaurav Gupta ◽  
Dinesh Kumar Chellappan ◽  
...  
Keyword(s):  
Antioxidant Activity ◽  
Ethyl Acetate ◽  
Petroleum Ether ◽  
Ethyl Acetate Extract ◽  
Petroleum Ether Extract ◽  
Inflammatory Activity ◽  
Ether Extract ◽  
Membrane Stabilization ◽  
Leaf Extracts ◽  
Anti Inflammatory

Aims: The present investigation was aimed at exploring the phytoconstituents using Gas Chromatography Mass Spectroscopy and to evaluate antioxidant and anti-inflammatory properties of the leaf extracts. Materials and Methods: The extracts were obtained sequentially with petroleum ether, ethyl acetate and water using soxhlet apparatus. The anti-inflammatory property of the identified compounds using GC- MS spectroscopy was evaluated in silico. The antioxidant activity was performed by DPPH and H2O2 method whereas anti-inflammatory study was carried out by HRBC membrane stabilization method. Terpenoids were found to be major constituents in petroleum ether extract while, phenols and flavonoids were predominantly found in ethyl acetate extract. Results and Discussion: The GC-MS analysis of the extract revealed six major molecules including Squalene, 19β, 28- epoxyleanan-3-ol and 2-tu-Butyl-5-chloromethyl-3-methyl-4-oxoimidazolidine-1-carboxylic acid. The ethyl acetate extract showed a significant antioxidant activity (P<0.01) in both DPPH method (70.87 %) and H2O2 method (73.58%) at 200 µg mL-1 . Increased membrane stabilization of petroleum ether extract was observed in the in vitro anti-inflammatory activity study. A strong relationship between the terpenoid content and anti-inflammatory activity was obtained from the correlation (0.971) and docking study. Conclusion: These results justify T. involucrata to be a rich source of terpenoids with potent antiinflammatory property.

scholarly journals Evaluation of hair growth promoting activity of petroleum ether extract of Abrus precatorius Linn. on Wistar Albino rats

2019 ◽  
Vol 9 (2) ◽  
pp. 330-335
Author(s):  
Namrata Omhare ◽  
Pratibha Sahu ◽  
Shailee Gautam ◽  
Nidhi Jain
Keyword(s):  
Petroleum Ether ◽  
Hair Growth ◽  
Petroleum Ether Extract ◽  
Hair Follicles ◽  
Ether Extract ◽  
Standard Drug ◽  
Abrus Precatorius ◽  
Growth Initiation ◽  
Growth Promoting ◽  
Bald Patch

In present investigation was carried out to screening of hair growth promoting potentiality of petroleum ether extract of Abrus precatorius leaf. Preliminary chemical tests and TLC analysis revealed the presence flavonoids and saponins. Hair growth promoting activity of petroleum ether of Abrus precatorius was screened by considering different parameters which included time taken for covering bald patch, length of hair produced, percentage of hair follicles in anagen and telogen phases, time of hair growth initiation and completion and level of minerals in blood. The petroleum ether extract of Abrus precatorius showed a very good hair growth promoting activity at a dose of 300 mg/kg which was comparable to that of 2% minoxidil. After 30 days of treatment with test and standard drugs it was observed that, time taken for covering the bald patch, hair growth initiation and completion time and quantitative hair growth were found to be comparable to that of the standard drug. An increase in percentage of hair follicles turning from telogen phase to anagen phase was noted. The control treated group of animals showed poor hair growth for all the parameters. Keywords: Abrus precatorius Linn, Anagen, Catagen, Telogen, Minoxidil

scholarly journals Assessment of camel thorn (Alhagi maurorum) as new sources of bioactive compounds using GC-MS technique

Plant Omics ◽  
2019 ◽  
pp. 70-77
Author(s):  
Reham M. Mostafa ◽  
Heba S. Essawy
Keyword(s):  
Petroleum Ether ◽  
Methanolic Extract ◽  
Biological Activities ◽  
Chemical Constituents ◽  
Petroleum Ether Extract ◽  
Chemical Compounds ◽  
Mass Analysis ◽  
Hexadecanoic Acid ◽  
Anticancer Compounds ◽  
The Family

Alhagi maurorum (A. maurorum) is one of the medicinally important plants belonging to the family leguminasae, commonly known as camel thorn. This research was amid to identify the chemical compounds in the aerial part of A. maurorum using GC-mass analysis. Three solvents with different polarities were used for the extraction of chemical constituents (water, methanol and petroleum ether). The results of GC-MS analysis led to identification of various compounds. In total, thirty-nine compounds from petroleum ether extract, thirty-two compounds in methanolic extract and seventeen compounds in aqueous extract were identified. Majority of the identified compounds have been reported to possess many biological activities. Among them, we reported 10 new anticancer compounds (Vitamin E; Hexadecanoic acid; Stigmast-5-en-3-ol; Phytol,2-hexadecen-1-ol,3,7,11,15-tetramethyl; Squalene; Hexadecanoic acid; 2-hydroxy-1-(hydroxymethyl) ethyl ester; Oxime,methoxy-phenyl,methyl N-hydroxyben-zenecarboximidoate; Ergost-5-en-3-ol; 9,12- Octadecad-ienoic acid and Farnesol) from A. maurorum using three solvent, while the best effective solvent was petroluem ether. Therefore, we report that A. maurorum has great potential to be developed into anticancer drugs.

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