scholarly journals The Effects of Supplementing Lysophosphatidylcholine (LPC) in the Diet on Production Performance, Fat Digestibility, Blood Lipid Profile, and Gene Expression Related to Nutrients Transport in Small Intestine of Laying Hens

2020 ◽  
Vol 29 (3) ◽  
pp. 258-265
Author(s):  
Witchanun Juntanapum ◽  
Chaiyapoom Bunchasak ◽  
Theerawit Poeikhampha ◽  
Choawit Rakangthong ◽  
Kanokporn Poungpong
2020 ◽  
Vol 60 (6) ◽  
pp. 806
Author(s):  
Marcelise Regina Fachinello ◽  
Eliane Gasparino ◽  
André Vinicius Sturzenegger Partyka ◽  
Angélica de Souza Khatlab ◽  
Leandro Dalcin Castilha ◽  
...  

Lycopene has the highest antioxidant activity among carotenoids due to its high number of conjugated double bonds; thus, it can be used in pig diets to look for improvements in growth performance and health status, eliminating or preventing the formation of free radicals. Therefore, the aim of the present study was to investigate the effects of dietary lycopene on the growth performance, the gene expression of antioxidant enzymes and blood lipid profile of finishing pigs. In total, 40 barrows and 40 gilts (Piétrain × Landrace × Large White) were used, averaging 75.04 ± 1.6 kg of initial bodyweight. Pigs were distributed in a 2 × 5 factorial arrangement, consisting of two genders (male and female) and five dietary levels of lycopene (0, 12.5, 25.0, 37.5 and 50.0 mg/kg of diet) supplemented for 28 days. It was observed that gilts presented with average daily feed intake (P = 0.001) being lower and the gain:feed ratio (P = 0.001) higher than for barrows. Increasing dietary lycopene concentration provided a linear decrease in the gene expression of the enzymes superoxide dismutase (SOD1; P = 0.018) and catalase (P = 0.001) in the liver of gilts. The gilts showed a lower gene expression than did barrows for SOD1 gene (P = 0.001) receiving 50.0 mg lycopene/kg of diet and for catalase gene (P = 0.001) receiving of 0, 12.5 and 50.0 mg lycopene/kg of diet. Glutathione peroxidase showed a lower expression (P = 0.001) for gilts than for barrows. Total cholesterol, low-density lipoprotein (LDL) and LDL:high-density lipoprotein (HDL) ratio decreased (P = 0.001) as lycopene concentration increased in the diet. Increasing dietary lycopene in pig diets improved the lipid profile of the blood plasma, providing an increase in the concentration of high-density lipoprotein (HDL; P = 0.001). Gilts had greater plasma concentrations of urea (P = 0.001) and triglycerides (P = 0.001) and lower concentrations of HDL (P = 0.001), LDL (P = 0.001) and a lower LDL:HDL ratio (P = 0.004) than did barrows. Dietary lycopene up to 50 mg/kg does not affect the growth performance of pigs, acting as a potent modulator of the lipid profile and also reducing the plasma concentrations of total cholesterol and low-density lipoproteins, while increasing the high-density lipoproteins. In addition, lycopene also reduces the gene expression of superoxide dismutase and catalase enzymes in the liver of gilts.


Diabetes ◽  
2020 ◽  
Vol 69 (Supplement 1) ◽  
pp. 732-P
Author(s):  
NAN LI ◽  
YANRU WANG ◽  
BING ZHU ◽  
HANG SUN ◽  
PENG YANG ◽  
...  

Molecules ◽  
2021 ◽  
Vol 26 (16) ◽  
pp. 4720
Author(s):  
Arlindo César Matias Pereira ◽  
Helison de Oliveira Carvalho ◽  
Danna Emanuelle Santos Gonçalves ◽  
Karyny Roberta Tavares Picanço ◽  
Abrahão Victor Tavares de Lima Teixeira dos dos Santos ◽  
...  

This study aimed to evaluate and compare the effects of co-treatment with purified annatto oil (PAO) or its granules (GRA, Chronic®) with that of testosterone on the orchiectomy-induced osteoporosis in Wistar rats. After surgery, rats were treated from day 7 until day 45 with testosterone only (TES, 7 mg/kg, IM) or TES + PAO or GRA (200 mg/kg, p.o.). The following parameters were evaluated: food/water intake, weight, HDL, LDL, glucose, triglycerides (TG), total cholesterol (TC), alkaline phosphatase levels, blood phosphorus and calcium contents, femur weight, structure (through scanning electron microscopy), and calcium content (through atomic absorption spectrophotometry). Our results show that orchiectomy could significantly change the blood lipid profile and decrease bone integrity parameters. Testosterone reposition alone could improve some endpoints, including LDL, TC, bone weight, and bone calcium concentration. However, other parameters were not significantly improved. Co-treatment with PAO or GRA improved the blood lipid profile and bone integrity more significantly and improved some endpoints not affected by testosterone reposition alone (such as TG levels and trabeculae sizes). The results suggest that co-treatment with annatto products improved the blood lipid profile and the anti-osteoporosis effects of testosterone. Overall, GRA had better results than PAO.


2012 ◽  
Vol 5 (1) ◽  
Author(s):  
Ana Elisa Madalena Rinaldi ◽  
Erick Prado de Oliveira ◽  
Fernando Moreto ◽  
Gleice Fernanda Costa Pinto Gabriel ◽  
José Eduardo Corrente ◽  
...  

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