scholarly journals Comentarios biomorfológicos y clínicos sobre el género fusarium. Hialohifomicosis en uñas

2019 ◽  
Vol 3 (3) ◽  
Author(s):  
E. Piontelli L. ◽  
M. A. Toro S.M.

En una breve reseña sobre algunos aspectos biológicos, taxonómicos y clínicos inherentes al género Fusarium, se presentan 12 casos clínicos de hialohifomicosis en uñas y uno en córnea. La especie dominante fue F. oxysporum (8/12); F. moniliferme y F. solani se aislaron una sola vez, mientras Fusarium spp, 2 veces. La combinación de Fusarium con otra u otras especies, se detectó en 4 casos, ya sea junto a Trichophyton rubrum, T. mentagrophytes, Candida albicans y Scopulariopsis brevicaulis.

2013 ◽  
Vol 45 (2) ◽  
pp. 197-205
Author(s):  
Magdalena Rusicka ◽  
Grażyna Lipowczan

The mycobiota responsible for the development of pathological changes of the skin and its adnexa in patients presenting at the Specialist Regional Hospital, Łódź, with suspected superficial mycosis between 01 May 2003 and 30 April 2005 is analyzed. In total of 2144 isolations 39.96% were dermatophytes, 39.39% were yeast-like fungi and 20.65% were moulds. <em>Candida albicans</em> was the most frequently diagnosed species in fallowed by <em>Trichophyton rubrum</em>.


2016 ◽  
Vol 18 (6) ◽  
pp. 953
Author(s):  
Gloria Ines Estrada Salazar ◽  
José A. Chacón-Cardona

Resumen:Objetivo: Determinar la frecuencia de las dermatomicosis en personas de diferentes instituciones de atención social en la ciudad de Manizales durante el año 2011. Método: Mediante la toma de muestras de los sitios que presentaban algún tipo de lesión sospechosa de ser una micosis cutánea, se hizo un análisis directo con KOH y cultivo en medios de Saboureaud y Mycosel. Se aplicó un instrumento de recolección de información para establecer  factores asociados con la presencia de estos microorganismos.Resultados: Los hongos levaduriformes encontrados con mayor frecuencia fueron: Candida albicans, Trichosporon sp, y los mohos saprofitos Penicillium sp, fusarium sp; seguido de hongos dermatofitos como: Trichophyton mentagrophites, Trichophyton rubrum, Epidermophyton floccosum y Microsporum gypseum. Las lesiones secas y descamativas se encontraron con mayor frecuencia. El compartir baños y vivir en hacinamiento y el uso de elementos comunes fueron los factores asociados más importantes en este estudio.Conclusiones. Las dermatomicosis son frecuentes en poblaciones vulnerables y se asocian a diferentes factores muy similares a los encontrados en otros estudios de igual naturaleza.    Palabras clave: dermatomicosis, onicomicosis, jóvenes, ancianos, factores asociados. Summary:Objective: To determine the frequency of ringworm in people of different social care institutions in the city of Manizales in 2011.Method: Using the sampling sites that had some kind of suspicious lesion from a cutaneous mycosis, direct analysis with KOH and culture media was Saboureaud and Mycosel. An instrument of data collection was used to establish factors associated with the presence of these microorganisms.Results: The yeast found most frequently were: Candida albicans, Trichosporon sp and Penicillium molds saprophytes sp, Fusarium sp, followed by dermatophyte fungi such as Trichophyton mentagrophytes, Trichophyton rubrum, Epidermophyton floccosum and Microsporum gypseum. Dry scaly lesions were found more frequently. The shared bathrooms and living in overcrowded and the use of common elements were the most important in this study associated factors.Conclusions: Dermatomycoses are common in vulnerable populations and are associated with different very similar to those found in other studies of the same nature factors. Keywords: ringworm, onychomycosis, young, old, associated factors.


F1000Research ◽  
2018 ◽  
Vol 7 ◽  
pp. 559
Author(s):  
Tatiana de los Ángeles Mosquera Tayupanta ◽  
Sandra Elizabeth Ayala Valarezo ◽  
Tatiana Alexandra Vasquez Villareal ◽  
María Belén Montaluisa Álvarez

Background: Currently, there is a trend towards using natural and ethnopharmacological species with therapeutic potential. This investigation evaluated the antifungal activity of two species in the Ecuadorian Andes, which are used in treating dermatomycosis: Ambrosia arborescens Mill. (Marco) and Aristeguietia glutinosa Lam. (Matico). Methods: We worked with seven concentrations (100 to 700ppm) of Ambrosia arborescens Mill. extract and ten concentrations (0.5 to 5%) of essential oil (EO) of Aristeguietia glutinosa Lam. on Trichophyton mentagrophytes ATCC 9533, Trichophyton rubrum ATCC 28188, Microsporum canis ATCC 36299 and Candida albicans ATCC 10231. The methodology used was a modified version of the Kirby-Bauer method, using diffusion in agar wells. Results: The Tukey test, after the one-way Anova, determined effective concentrations of EO: 5% for Trichophyton mentagrophytes, 4.5% for Trichophyton rubrum, 5% for Microsporum canis and 2% for Candida albicans. In the extracts, the concentration of 700ppm was used for Trichophyton mentagrophytes, Trichophyton rubrum, and 600ppm for Microsporum canis and Candida albicans. Conclusions: The evaluation of the antifungal activity of the Ambrosia arborescens extract showed inhibition in the studied dermatophytes in each one of the planted concentrations (100 to 700ppm). The evaluation of the antifungal activity of Aristeguietia glutinosa EO showed inhibition in the studied dermatophytes in each of the planted concentrations (0.5 to 5%).


Author(s):  
Yuli Wahyu Trimulyani ◽  
Nurma Suri ◽  
Niken Dwi Astarina

Traditional medicine is used as natural because it has small effects and more economical than the synthetic drugs. One example of the plants used as a Traditional medicine are Curcuma zedoaria. The study to examine the activity fraction of Curcuma zedoaria rhizome ethanol extract agains Candida albicans and Trichophyton rubrum. The simplisia of Curcuma zedoaria rhizome was extracted with ethanol 70% using a maceration method. Thick extracts were then fractionated using saveral solven such as n-heksane, chloroform and ethanol. The testing method used disc antifungi activity with the concentration of 6.25%, 12.5%, 25%, 50%, 75%, ketokonazol as the positive control and aquades as the resolvent. The test compounds Thin Layer Chromatography (TLC) method with eluen chloroform: methanol: water (2:3:5(v/v/v)) and phase uses G60F254 had been done. The result showed that Curcuma zedoaria rhizome significantly inhibit of C. albicans and T. rubrum the best inhibit zone diameter that are concentration of 75% for both of them with a diameter 8.98 mm in C. albicans and 11.66 mm in T. rubrum. Minimum Inhibitory Concentration (MIC) C. albicans is obtained on concentration of 6.25% and T. rubrum is concentration on of 12.5%. The TLC results showed a compound of flavonoids (Rf 0.88), saponins (Rf 0.74), tannins (Rf 0.86). Minimum Inhibitory Concentration (MIC) in C. albicans and T. rubrum are fungistatik and Minimum Bactericidal Concentration (MBC) are not fungisid for both of them. The ethanol fraction of Curcuma zedoaria rhizome has an activity as an antifungal against C. albicans and T. Rubrum with flavonoids, tannins and saponins. Keywords: Antifungi, Candida albicans, Curcuma zedoaria, Fungistatic, Trichophyton rubrum.


2021 ◽  
Vol 10 (2) ◽  
Author(s):  
Patrícia Ferraccioli Siqueira Lemos ◽  
Magda Guimarães de Araújo Faria ◽  
Fabiana Ferreira Koopmans ◽  
Donizete Vago Daher ◽  
Bruna Maiara Ferreira Barreto Pires ◽  
...  

Objetivo: Analisar, segundo as produções científicas nacionais e internacionais, a presença de infecções fúngicas cutâneas periféricas e os principais fungos identificados em pessoas com diabetes mellitus tipo 2. Método: Trata-se de revisão integrativa de literatura, com estudos publicados nas bases de dados MEDLINE, LILACS, Web of Science e bibliotecas eletrônicas BDENF, SciELO e PubMed.  Resultados: Os principais dermatófitos encontrados nas culturas isoladas de indivíduos com diabetes foram o Trichophyton rubrum e o Trichophyton metagraphyte, assim como, os fungos do tipo leveduras identificados foram a Candida albicans e a Candida tropicalis, sendo a prevalência de onicomicose 2,5 vezes mais elevada em pessoas com diabetes. Conclusão: As infecções fúngicas superficiais e cutâneas periféricas não se referem apenas de complicações estéticas ou cosméticas, principalmente para as pessoas com diabetes, mas sim, de um sério problema de saúde pública, devido às complicações e o seu potencial de morbi-mortalidade


Author(s):  
GM Greeshma ◽  
JM Aswathy ◽  
Murukan Greeshma ◽  
Lawarence Bosco ◽  
Murugan K

Tribal people use the flower extract of <em>Caesalpinia pulcherrima<strong> </strong></em>to cure liver, stomach and skin disorders in Indian traditional medicine. This study aimed to evaluate the protective roles of purified quercetin extracted from suspension culture of <em>C. pulcherrima</em> against selected bacterial and fungal pathogens. A simple protocol was developed for callus production using leaf explants<em>.</em> 2, 4-D (2.5 mg/l), BAP (2.5 mg/l) + kin (1 mg/ml) was effective for optimal callus induction. Subsequently, cell suspension culture was established.  Role of effect of elicitors in cell suspension culture was carried. Sucrose, ABA and salicylic acid (SA) at different concentrations influenced cell biomass and quercetin accumulation. Cells cultured in the medium fortified with 45 g/L sucrose without ABA/SA showed the highest quercetin content (16.5 mg/g). Flavonoids was purified, fractionated by HPLC-DAD followed by NMR revealed the presence of quercetin, isoquercetin, quercetrin, rutin, quercetin 3-O-β-D-xyloside, quercetin 3-Oarabinopyranoside, quercetin 3-O- α-arabinopyranosyl (1→2) β-galactopyranoside,  isorhamnetin 3-O-rutinoside and an unknown compound. Subsequently, anthocyanin was evaluated for antimicrobial activity against selected Gram-positive bacteria (<em>S. aureus, Bacillus subtilis</em>, and <em>Enterococcus faecalis</em><em>)</em>, Gram-negative bacteria (<em>E. coli, </em>and <em>Pseudomonas aeruginosa</em>) and fungi such as <em>Aspergillus flavus, Candida albicans </em>and <em>Trichophyton rubrum</em>. Quercetin was found to be active against four bacteria and the fungi- <em>Candida albicans</em>. The highest inhibitory effects were found on <em>S. aureus</em> and <em>Enterococcus faecalis</em>. Gram negative bacteria showed more resistance i.e., with insignificant MIC and MBC values. Among the fungi, <em>Aspergillus flavus</em> and <em>Trichophyton rubrum</em> displayed remarkable MIC and MKC values. These results suggest that quercetin may be used as a natural antimicrobial agent. Future works are designed to trace the molecular mechanism of antimicrobial potentiality of quercetin against these tested pathogens


2020 ◽  
Vol 11 ◽  
Author(s):  
Letícia Morais Garcia ◽  
Caroline Barcelos Costa-Orlandi ◽  
Níura Madalena Bila ◽  
Carolina Orlando Vaso ◽  
Larissa Naiara Carvalho Gonçalves ◽  
...  

2020 ◽  
Vol 110 (3) ◽  
Author(s):  
Noureddine Litaiem ◽  
Ines Nakouri ◽  
Sabrine Bouhlel ◽  
Yasmine Mansour ◽  
Meriem Bouchakoua ◽  
...  

Background Onychomycosis is the most common infectious nail disorder. Direct mycologic examination is still the cornerstone of diagnosis; however, it may take several weeks to obtain a result. Recently some dermoscopic patterns that can be useful in the diagnosis of onychomycosis were described. However, published data on dermoscopic features of onychomycosis are still limited. Methods We performed a prospective dermoscopic study of patients with positive fungal culture between April and December 2016. Patients with a final diagnosis of psoriasis or lichen planus were excluded from the study. Dermoscopy (polarized and nonpolarized) was performed. Results Thirty-seven patients were enrolled, 24 women and 13 men (median ± SD age, 48.6 ± 16.1 years). Nail samples were culture positive for Trichophyton rubrum (89.2%), Trichophyton interdigitale (8.1%), and Candida albicans (2.7%). Distal and lateral subungual onychomycosis was the most frequent clinical subtype (59.5%). The most frequent dermoscopic features were subungual keratosis (73.0%), distal subungual longitudinal striae (70.3%), spikes of the proximal margin of an onycholytic area (59.5%), transverse superficial leukonychia (29.7%), and linear hemorrhage (13.5%). Brown chromonychia was most frequently seen with nonpolarized dermoscopy (66.6% versus 24%; P = .027). Conclusions Specific dermoscopic signs of onychomycosis are mostly related to the proximal invasion of the nail plate. Detection of these signs is simple and can, in some cases, help avoid mycologic testing.


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