scholarly journals KARAKTERISTIK PASIEN EFUSI PLEURA DI KOTA JAMBI

2020 ◽  
Vol 8 (1) ◽  
pp. 54-59
Author(s):  
Hasna Dewi ◽  
Fairuz Fairuz
Keyword(s):  
Pleural Effusion ◽  
Malignant Pleural Effusion ◽  
Inflammatory Process ◽  
Pleural Cavity ◽  
Descriptive Study ◽  
Primary Data ◽  
Pleural Effusions ◽  
Cytological Examination ◽  
Male Sex ◽  
The Right

ABSTRACT Introduction Pleural effusion is a condition where the fluid either a transudate or an exudate accumulate in pleural cavity. Disease that can cause pleural effusion can be either a malignancy or an inflammatory process. Intratoracal and extratoracal malignancies can cause pleural effusion (malignant pleural effusion / MPE). The aim of this study was to describe the characteristics of patients with pleural effusion and the proportion of malignant pleural effusion in Jambi City. Methods This research is a descriptive study with a retrospective approach, was conducted in 138 sample of pleural effusion patients at two hospital Raden Mattaher and H. Abdul Manap Hospital in 2017-2018. The data was taken from the patient's medical record and primary data in the form of cytological examination results. Results of this study found that most patients with pleural effusion were at the age 40 - 59 years (52.72%), and more men than women (63.77%). The location of the most common effusion was the right hemithorax (52.9%) and the proportion of malignant pleural effusion was only 32.61%. Conclusion Pleural effusion often occurs at the age of 40-59 years with male sex predominant. Most pleural effusions are negative for malignancy, MPE was only 32,61 %. Keywords: characteristics, cytology, malignant pleural effusion (MPE)   ABSTRAK Pendahuluan Efusi pleura merupakan keadaan terkumpulnya cairan di dalam rongga pleura, baik itu transudat maupun eksudat. Penyakit yang dapat menyebabkan terjadinya efusi pleura dapat berupa keganasan maupun proses inflamasi. Keganasan intratorakal dan ekstratorakal dapat menimbulkan terjadinya efusi pleura (efusi pleura maligna/EPM). Sampai sekarang belum ada data deskriptif mengenai efusi pleura di kota Jambi. Adapun tujuan penelitian ini mengetahui karakteristik pasien dengan efusi pleura dan proporsi kejadian efusi pleura maligna di Kota Jambi. Metode Penelitian ini adalah penelitian deskritif dengan pendekatan retrospektif. Sampel penelitian merupakan pasien efusi pleura di kota Jambi dari dua RS pemerintah yaitu RSUD Raden Mattaher dan RSUD H. Abdul Manap tahun 2017- 2018 sebanyak 138 sampel. Cara pengambilan sampel dalam penelitan yaitu purposive sampling. Data yang diambil adalah data dari rekam medis pasien dan data primer berupa hasil pemeriksaan sitologi Hasil penelitian ini mendapatkan pasien efusi pleura paling banyak pada proporsi umur 40 – 59 tahun (52,72 %). Jenis kelamin terbanyak adalah laki-laki dengan 88 pasien (63,77%). Lokasi efusi tersering adalah hemithorak dekstra (52,9 %) dan proporsi kejadian efusi pleura maligna hanya 32,61 %. Simpulan Efusi pleura sering terjadi pada usia 40-59 tahun dengan jenis kelamin laki-laki. Sebagian besar efusi pleura adalah negatif maligna, hanya 32,61 % berupa EPM. Kata kunci: efusi pleura maligna (EPM), karakteristik, sitologi

Heparan sulfate chains contribute to the anticoagulant milieu in malignant pleural effusion

Thorax ◽  
2019 ◽  
Vol 75 (2) ◽  
pp. 143-152 ◽  
Author(s):  
Emilia Hardak ◽  
Eli Peled ◽  
Yonatan Crispel ◽  
Shourouk Ghanem ◽  
Judith Attias ◽  
...  
Keyword(s):  
Cell Proliferation ◽  
Pleural Effusion ◽  
Heparan Sulfate ◽  
Tumour Cell ◽  
Malignant Pleural Effusion ◽  
Pleural Cavity ◽  
Therapeutic Option ◽  
Factor Xa ◽  
Pleural Effusions ◽  
Cell Proliferation Inhibition

BackgroundWhile malignant pleural effusion (MPE) is a common and significant cause of morbidity in patients with cancer, current treatment options are limited. Human heparanase, involved in angiogenesis and metastasis, cleaves heparan sulfate (HS) side chains on the cell surface.AimsTo explore the coagulation milieu in MPE and infectious pleural effusion (IPE) focusing on the involvement of heparanase.MethodsSamples of 30 patients with MPE and 44 patients with IPE were evaluated in comparison to those of 33 patients with transudate pleural effusions, using heparanase ELISA, heparanase procoagulant activity assay, thrombin and factor Xa chromogenic assays and thromboelastography. A cell proliferation assay was performed. EMT-6 breast cancer cells were injected to the pleural cavity of mice. A peptide inhibiting heparanase activity was administered subcutaneously.ResultsLevels of heparanase, factor Xa and thrombin were significantly higher in exudate than transudate. Thromboelastography detected almost no thrombus formation in the whole blood, mainly on MPE addition. This effect was completely reversed by bacterial heparinase. Direct measurement revealed high levels of HS chains in pleural effusions. Higher proliferation was observed in tumour cell lines incubated with exudate than with transudate and it was reduced when bacterial heparinase was added. The tumour size in the pleural cavity of mice treated with the heparanase inhibitor were significantly smaller compared with control (p=0.005).ConclusionsHS chains released by heparanase form an anticoagulant milieu in MPE, preventing local thrombosis and enabling tumour cell proliferation. Inhibition of heparanase might provide a therapeutic option for patients with recurrent MPE.

scholarly journals Chemical pleurodesis using bleomycin in treatment of patients with transsudative pleural effusion in hepatic failure

2017 ◽  
Vol 176 (3) ◽  
pp. 52-55 ◽  
Author(s):  
A. L. Akopov ◽  
A. .. Carlson ◽  
S. D. Gorbunkov ◽  
A. S. Agishev ◽  
A. I. Romanikhin
Keyword(s):  
Pleural Effusion ◽  
Hepatic Failure ◽  
Pleural Cavity ◽  
Hepatic Coma ◽  
Single Case ◽  
Pleural Effusions ◽  
Lethal Outcome ◽  
Chemical Pleurodesis ◽  
Safe Method ◽  
The Right

OBJECTIVE. The authors analyzed the efficacy of bleomycin application as sclerosing agent in patients with transudative pleural effusion in consequence of hepatic failure. MATERIAL AND METHODS. The research included 7 patients with right side hepatic transudative pleural effusion who didn’t respond to conservative medical treatment. Drainage of the right pleural cavity with following injection of bleomycin were performed for all the patients. RESULTS. This procedure was effective in 6 out of 7 patients (86 %). There was a single case of recurrence and lethal outcome (14 %) due to hepatic coma. There weren’t noted any severe side effects during 6 months after induction of bleomycin. CONCLUSIONS. Pleurodesis using bleomycin appeared to be effective and safe method of treatment for patients with hepatic transudative pleural effusions.

scholarly journals A Case with Severe Endometriosis, Ovarian Hyperstimulation Syndrome, and Isolated Unilateral Pleural Effusion after IVF

2017 ◽  
Vol 2017 ◽  
pp. 1-4
Author(s):  
Negjyp Sopa ◽  
Elisabeth Clare Larsen ◽  
Anders Nyboe Andersen
Keyword(s):  
Pleural Effusion ◽  
Ovarian Hyperstimulation Syndrome ◽  
Common Finding ◽  
Ovarian Hyperstimulation ◽  
Pleural Effusions ◽  
Luteal Support ◽  
Vitro Fertilization ◽  
Fluid Production ◽  
The Right

We present a very rare case of right-sided isolated pleural effusion in a patient with severe endometriosis who, in relation to in vitro fertilization (IVF), developed ovarian hyperstimulation syndrome (OHSS). Earlier laparotomy showed grade IV endometriosis including endometriotic implants of the diaphragm. The patient had no known risk factors for OHSS and only a moderate number of oocytes aspirated. She received, however, repeated hCG injections for luteal support. The patient did not achieve pregnancy but was hospitalized due to pain in the right side of the chest and dyspnoea. A chest computed tomography (CT) showed a pleural effusion on the right side. Total of 1000 ml of pleural fluid was drained after a single thoracentesis. After three days, the symptoms and fluid production ceased. Ascites is a common finding in OHSS, but pleural effusions are rare. Further, isolated pleural effusions have not previously been described in a patient with endometriosis. We suggest that the repeated hCG injections induced effusions from the endometriotic lesions at the diaphragm and as a consequence this patient developed isolated hydrothorax.

scholarly journals Tanggung Jawab Para Pihak Dalam Pembuatan Akta Jaminan Fidusia Pada Notaris Di Busan Auto Finance Rembang

Jurnal Akta ◽  
2018 ◽  
Vol 5 (1) ◽  
pp. 211
Author(s):  
Magmun Migfar ◽  
Amin Purnawan
Keyword(s):  
Analytical Data ◽  
Data Use ◽  
Secondary Data ◽  
Descriptive Study ◽  
Third Party ◽  
Economic Conditions ◽  
Primary Data ◽  
Timely Manner ◽  
The Right ◽  
Settlement Of Disputes

ABSTRAKDalam memberikan kredit, Perusahaan Pembiayaan wajib mempunyai keyakinan didasarkan pada unsur perinsip kehati-hatian biasa di kenal dengan 5C, yaitu terdiri dari character (watak), capacity (kemampuan), capital (modal), collateral (jaminan), dan condition of economic (kondisi ekonomi).Di dalam penelitian penulis membuat rumusan masalahanuntuk mengetahui tanggung jawab para pihak dalam pembutan akta jaminan fidusia pada Notaris dan penyelesaian sengketanya apabila debitur mengalihkan objek jaminan fidusia tanpa persetujuan tertulis oleh pihak PT. Bussan auto Finance (BAF) Rembang.Penelitian ini merupakan penelitian yang bersifat diskriptif dan apabila dilihat dari tujuannya teremasuk penelitian hukum empiris. Lokasi penelitian di PT. BAF Rembang. Jenis data yang digunakan meliputi data primer dan data sekunder. Teknik pengumpulan data yang dipergunakan yaitu melalui penelitian kepustakaan dan wawancara. Analisis data menggunakan kualitatif analitis.Berdasarkan hasil penelitian dapat diketahui dalam perjanjian pembiayaan antara kreditur dan debitur saling mengikatkan diri, debitur harus membaca dan memahami surat perjanjian pembiayaan, sebelum melakukan kesepakatan sengan Leasing, setelah menandatangi perjanjian pembiayaan, debitur harus memenuhi kewajiban membayar angsuran secara tepat waktu sesuai dengan besaran dan tanggal yang telah disepakati, kemudian timbulah hak dan kewajiban supaya jangan sampai ada konflik atau kesalah pahaman yang bias merugikan debitur dikemudian hari.Dalam hal benda jaminan yang menjadi objek jaminan fidusia dialihkan kepada pihak ketiga berlaku asas drot de suite, kreditur tetap dapat mengeksekusi benda jaminan tersebut di tangan siapaun benda tersebut berada. Pengalihan benda yang menjadi objek jaminan fidusia pada pihak ketiga dan seterusnya tidak menghalangi hak kreditur untuk tetap mengeksekusi benda jaminan fidusia tersebut. Memang dalam peneyelesain sengketa benda jamian fidusia di PT BAF Rembang masih mengedepankan cara musyawarah dahulu akan tetapi jika PT BAF Rembang berpedoman pada POJK No.29/POJK.05/2014 Tentang Penyelenggaraan Usaha Perusahaan Pembiayaan dan perlu adanya pendampingan dai pihak kepolisian maka akan sangat mudah dan mungkin untuk mengatasi debitur yang nakal.Kata kunci : Debitur, Kreditur, Eksekusi Benda Jaminan Fidusia.           ABSTRACTIn granting credit, a Financing Company must have confidence based on the usual principle of prudence known as 5C, which consists of character, capability, capital, collateral and condition of economic ( economic conditions). In the study the authors make the formulation of the problem to know the responsibility of the parties in the fiduciary guarantee certificate pembutan notary and settlement of disputes if the debtor divert the fiduciary guarantee object without written approval by the PT. Bussan auto Finance (BAF) Rembang.Penelitian is a descriptive study and when viewed from its purpose including research empirical law. Research location at PT. BAF Rembang. Types of data used include primary data and secondary data. Data collection techniques used are through literature research and interviews. Analytical data use qualitative analytical.Based on the results of the research can be known in the financing agreement between the creditor and the debtor bind each other, the debtor must read and understand the letter of financing agreement, before making leasing agreement, after signing the financing agreement, the debtor must meet the obligation to pay installments in a timely manner in accordance with the amount and date which has been agreed, then arise rights and obligations so that there will be no conflicts or misunderstandings that bias detrimental to the debtor in the future. In the event that the collateral object becomes the object of fiduciary guarantee transferred to a third party applies the principle of drot de suite, the lender can still execute the guarantee object in the hands of whoever the object is located. The transfer of objects which become the object of fiduciary collateral to a third party and so on shall not preclude the right of the creditor to keep executing the fiduciary assurance object. Indeed, in peneyelesain dispute fiduciary jamian objects in PT BAF Rembang still put forward the first musyawarah way but if PT BAF Rembang based on POJK No.29 / POJK.05 / 2014 About the Implementation of Financing Company Business and the need for assistance from the police then it will be very easy and possibly to deal with naughty debtors.Keywords: Debtor, Creditors, Execution of Fiduciary Guarantee Items.

Pleural tumours

2010 ◽  
pp. 3534-3539
Author(s):  
Robert J.O. Davies ◽  
Y.C. Gary Lee
Keyword(s):  
Pleural Effusion ◽  
Case History ◽  
Pleural Cavity ◽  
Solitary Fibrous Tumour ◽  
Pleural Effusions ◽  
Old Chinese ◽  
Benign Tumours

Case History—A 54 yr old Asian man, and a 19 yr old Chinese man, both with pleural effusions. Case History—A 68 yr old man with a pleural effusion. Benign tumours are rare in the pleural cavity, with solitary fibrous tumour of the pleura, the most frequent of these rarities....

scholarly journals Profil hasil pemeriksaan foto toraks pada pasien pneumotoraks di Bagian / SMF Radiologi FK Unsrat RSUP Prof. Dr. R. D. Kandou Manado periode Januari 2015 – Agustus 2016

e-CliniC ◽  
2016 ◽  
Vol 4 (2) ◽  
Author(s):  
Windy D.P. Masengi ◽  
Elvie Loho ◽  
Vonny Tubagus
Keyword(s):  
Medical Records ◽  
Spontaneous Pneumothorax ◽  
Pleural Cavity ◽  
Secondary Data ◽  
Descriptive Study ◽  
Age Group ◽  
X Ray ◽  
Secondary Spontaneous Pneumothorax ◽  
Chest X Ray ◽  
The Right

Abstract: Radiology examination especially chest x-ray can enforce various kinds of pulmonary diseases inter alia pneumothorax. Pneumothorax is defined as the presence of air in the pleural cavity. The causes of pneumothorax are very diverse ranging from idiopathic, infection, trauma, and iatrogenic. This study was aimed to obtain the profile of chest x-ray in patients with pneumothorax. This was a retrospective descriptive study by using secondary data from the medical records at the Department of Radiology Prof. Dr. R. D. Kandou Hospital Manado from January 2015 to August 2016. Samples were the medical records of patients that were radiologically diagnosed as pneumothorax. There were 41 patients that were diagnosed radiologically as pneumothorax. The majority of cases were male (90.2%), age group >50 years (36.6%), location of lesion in the right hemithorax (53.7%), and secondary spontaneous pneumothorax as the etiology (43,9 %). Conclusion: In this study, pneumothorax was more common among males, age group of ≥50 years, and secondary spontaneous pneumothorax as the etiology of pneumothorax.Keywords: pneumothorax, radiology, chest x-ray Abstrak: Pemeriksaan radiologi khususnya foto toraks dapat menegakkan berbagai macam diagnosis penyakit paru, salah satunya ialah pneumotoraks. Pneumotoraks adalah terdapatnya udara bebas didalam rongga pleura dengan penyebab yang sangat beragam mulai dari idiopatik, infeksi, trauma, maupun iatrogenik. Penelitian ini bertujuan untuk mengetahui profil hasil pemeriksaan foto toraks pada pasien pneumotoraks. Jenis penelitian ialah deskriptif retrospektif dengan pengambilan data di Bagian Radiologi RSUP Prof. Dr. R. D. Kandou Manado pada bulan Januari 2015 sampai dengan Agustus 2016. Sampel yaitu data rekam medik pasien yang didiagnosis pneumotoraks secara radiologis sebanyak 41 pasien. Yang tersering ditemukan ialah pasien laki-laki sebanyak 37 orang (90,2%), kelompok usia >50 tahun sebanyak 15 orang (36,6%), lokasi lesi hemitoraks deksra sebanyak 22 kasus (53,7%), serta etiologi pneumotoraks spontan sekunder sebanyak 18 kasus (43,9%). Simpulan: Pada penelitian ini didapatkan pneumotoraks paling banyak pada laki-laki, kelompok usia ≥50 tahun, dengan pneumotoraks spontan sekunder sebagai etiologi tersering. Kata kunci: pneumotoraks, radiologi, foto toraks

scholarly journals Administration of the adriamycin-containing poly (L-lactic acid) microspheres into the pleural cavity of patients with malignant pleural effusion.

1990 ◽  
Vol 5 (1) ◽  
pp. 23-27 ◽  
Author(s):  
Osamu Ihe ◽  
Shigeki Hitomi ◽  
Yasuhiko Shimizu ◽  
Ryoichi Wada ◽  
Satoshi Watanabe ◽  
...  
Keyword(s):  
Lactic Acid ◽  
Pleural Effusion ◽  
Malignant Pleural Effusion ◽  
Pleural Cavity

scholarly journals Prolonged retention of liposomes in the pleural cavity of normal mice and high tumor distribution in mice with malignant pleural effusion, after intrapleural injection

2019 ◽  
Vol Volume 14 ◽  
pp. 3773-3784 ◽  
Author(s):  
Antonia Marazioti ◽  
Konstantina Papadia ◽  
Anastasios Giannou ◽  
Georgios T. Stathopoulos ◽  
Sophia Antimisiaris
Keyword(s):  
Pleural Effusion ◽  
Malignant Pleural Effusion ◽  
Pleural Cavity ◽  
Prolonged Retention ◽  
Tumor Distribution

scholarly journals PAI-1 Level Differences in Malignant Plural Effusion, Parapneumonic Pleuritis, and Cardiac Hydrothorax

Medicina ◽  
2019 ◽  
Vol 55 (9) ◽  
pp. 567
Author(s):  
Zentina ◽  
Stukena ◽  
Krams ◽  
Lejnieks
Keyword(s):  
Pleural Effusion ◽  
Fibrinolytic Activity ◽  
Malignant Pleural Effusion ◽  
Clinical Manifestations ◽  
Plasminogen Activator Inhibitor ◽  
Pleural Effusions ◽  
Plasminogen Activator Inhibitor 1 ◽  
Significant Difference ◽  
Activator Inhibitor ◽  
Pai 1

Background and Objectives: Plasminogen activator inhibitor-1 (PAI-1) is a fibrinolytic system enzyme whose role in various fibrinolytic processes is currently unknown. In clinical manifestations of pleural liquids of diverse etiology, various levels of fibrinolytic activity can be observed—parapneumonic processes tend to loculate in fibrin septa, while malignant pleural effusion (MPE) does not. The purpose of this study was to determine possible differences in PAI-1 levels in pleural effusions of varied etiology. Material and Methods: PAI-1 level in pleural effusion and serum was determined in 144 patients with pleural effusions of various etiology (cardiac hydrothorax—42 patients (29.2%), MPE—67 patients (46.5%), parapneumonic pleuritis—27 (18.8%), tuberculous pleuritis—6 patients (4.1%), pancreatogenic pleuritis—1 patient (0.7%) and pulmonary artery thromboembolism with pleuritis—1 patient (0.7%)). Results: The median PAI-1 level (ng/mL) was the highest in the parapneumonic pleuritis group both in the effusion and the serum, with values of 291 (213–499) ng/mL and 204 (151–412) ng/mL, respectively, resulting in a statistically significant difference (p < 0.001) from the cardiac hydrothorax and MPE groups. However, there was no statistically significant difference between PAI-1 levels in the pleural effusion and serum in the cardiac hydrothorax and MPE groups. Conclusion: The PAI-1 level in MPE and cardiac hydrothorax was statistically significantly lower than in parapneumonic pleuritis.

Suspicious for Malignancy Diagnoses on Pleural Effusion Cytology

2020 ◽  
Vol 154 (3) ◽  
pp. 394-402
Author(s):  
Erika F Rodriguez ◽  
Ricardo G Pastorello ◽  
Paul Morris ◽  
Mauro Saieg ◽  
Sayanan Chowsilpa ◽  
...  
Keyword(s):  
Pleural Effusion ◽  
Malignant Pleural Effusion ◽  
Sample Volume ◽  
Definitive Diagnosis ◽  
Cell Tumor ◽  
Pleural Effusions ◽  
Not Otherwise Specified ◽  
Significant Difference ◽  
Pathology Reports ◽  
Average Sample

Abstract Objectives A definitive diagnosis of malignancy may not be possible in pleural effusions. We report our experience with the diagnosis of suspicious for malignancy (SFM) in pleural effusion. Methods A search for pleural effusions diagnosed as SFM (2008-2018) was performed. Patient records and pathology reports were reviewed. Specimens were subdivided into groups depending on volume (&lt;75, 75-400, &gt;400 mL). Diagnoses of malignant pleural effusion (MPE) served as controls. Results We identified 90 patients, with a mean age of 60.6 years. Diagnoses included suspicious for involvement by carcinoma/adenocarcinoma in 64.4%, leukemia/lymphoma in 15.6%, melanoma in 2.2%, sarcoma in 3.3%, germ cell tumor in 1.1%, and not otherwise specified in 13.3%. Immunostains were performed in 47.8% and considered inconclusive in 24%. Average sample volume was 419 mL. There was a statistically significant difference between the SFM vs MPE groups for volumes greater than 75 mL (P = .001, χ 2 test), with SFM having increased proportion of volumes  greater than 400 mL, compared with the MPE group. There was no statistically significant difference in mean overall survival when the groups were compared (P = .49). Conclusions Samples with low cellularity, scant cell blocks, and inconclusive immunostains may contribute to a suspicious category diagnosis in pleural effusions.

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