scholarly journals Platelet concentrates for periodontal regeneration

2020 ◽  
Vol 27 ◽  
pp. 55-65
Author(s):  
Prabha Kadakampallil John ◽  
Thomas George Valliaveettil ◽  
Annie Kitty George ◽  
Alenya Mary Pyas
Keyword(s):  
Wound Healing ◽  
Growth Factors ◽  
Surgical Procedures ◽  
Periodontal Regeneration ◽  
Review Article ◽  
Platelet Concentrates ◽  
Ability To Act ◽  
Derivatives Of

Platelet concentrates are derivatives of blood that aid in haemostasis and wound healing after periodontal regenerative procedures. Its ability to act as a natural scaffold of growth factors has gained significance in many surgical procedures. This review article aims to briefly describe the different platelet concentrates used in the field of periodontology.

scholarly journals Platelet Concentrates: A New Alternative to Bone Regeneration

2013 ◽  
Vol 2 (2) ◽  
pp. 118-121
Author(s):  
Naveen Chhabra ◽  
Shruti Chhabra ◽  
Puja Vaid
Keyword(s):  
Cell Proliferation ◽  
Wound Healing ◽  
Growth Factors ◽  
Bone Regeneration ◽  
Blood Clot ◽  
Review Article ◽  
Clinical Implications ◽  
Platelet Concentrates ◽  
Hard Tissue ◽  
Tissue Healing

ABSTRACT Platelets significantly promote soft and hard tissue healing owing to the abundance of growth factors present in them. These growth factors enhance the rate of wound healing by aiding in cell proliferation, differentiation, chemotaxis and angiogenesis. Thus using platelet concentrates is a simple way of enriching a natural blood clot with growth factors. The objective of this review article is to discuss the evolution of different platelet concentrates and their clinical implications. How to cite this article Chhabra S, Chhabra N, Vaid P. Platelet Concentrates: A New Alternative to Bone Regeneration. Int J Experiment Dent Sci 2013;2(2):118-121.

scholarly journals Stem Cells for Periodontal Regeneration

2013 ◽  
Vol 16 (1) ◽  
pp. 7-11 ◽  
Author(s):  
A. Pejcic ◽  
D. Kojovic ◽  
D. Mirkovic ◽  
I. Minic
Keyword(s):  
Stem Cells ◽  
Growth Factors ◽  
Surgical Procedures ◽  
Adult Stem Cells ◽  
Periodontal Regeneration ◽  
Human Stem Cells ◽  
Barrier Membranes ◽  
Periodontal Tissues ◽  
Grafting Materials ◽  
Potential Use

Abstract Periodontal regeneration is considered to be biologically possible but clinically unpredictable. In periodontitis, inflammation manifests clinically as loss of supporting periodontal tissues and regeneration of damaged tissue is the main goal of treatment. For decades, periodontists have sought to repair the damage through a variety of surgical procedures, and use of grafting materials and growth factors, and of barrier membranes. Reports have emerged that demonstrate which populations of adult stem cells reside in the periodontal ligaments of humans and other animals. This opens the way for new cell-based therapies for perio-dontal regeneration. This review provides an overview of adult human stem cells and their potential use in perio-dontal regeneration.

scholarly journals Contemporary Overview of Blood Concentrates in Oral and Maxillacial Surgery

2020 ◽  
Author(s):  
Onur Gönül ◽  
Ahmet Usame Çiçek ◽  
Murat Afat ◽  
Onur Atali ◽  
Faysal Uğurlu
Keyword(s):  
Wound Healing ◽  
Growth Factors ◽  
Healing Process ◽  
Platelet Concentrates ◽  
Medical Field ◽  
Over Time

It has always been a target to shorten and improve the healing process in medical field. Platelets with cytokines and growth factors in their structure have great importance on wound healing. Features of platelets gave the clinicians the idea of using platelet concentrates to promote the healing process. For this reason, many platelet-derived biomaterials have been tried in the medical field over the years. When approaching today, platelet concentrates have been found to be used medically, especially with the use of platelet rich plasmas (PRPs) and then platelet rich fibrins (PRFs). In particular, several studies conducted in recent years have revaled different blood concentrates. This chapter summarizes the develoment over time, properties and usage areas of blood concentrates in dentistry.

scholarly journals Preliminary Findings of α-Actinin-3 Gene Distribution in Elite Turkish Wind Surfers

2013 ◽  
Vol 16 (1) ◽  
pp. 69-72 ◽  
Author(s):  
K Ulucan ◽  
S Göle ◽  
N Altindas ◽  
A.I. Güney
Keyword(s):  
Stem Cells ◽  
Growth Factors ◽  
Surgical Procedures ◽  
Adult Stem Cells ◽  
Periodontal Regeneration ◽  
Human Stem Cells ◽  
Barrier Membranes ◽  
Periodontal Tissues ◽  
Grafting Materials ◽  
Potential Use

Abstract Periodontal regeneration is considered to be biologically possible but clinically unpredictable. In periodontitis, inflammation manifests clinically as loss of supporting periodontal tissues and regeneration of damaged tissue is the main goal of treatment. For decades, periodontists have sought to repair the damage through a variety of surgical procedures, and use of grafting materials and growth factors, and of barrier membranes. Reports have emerged that demonstrate which populations of adult stem cells reside in the periodontal ligaments of humans and other animals. This opens the way for new cell-based therapies for perio-dontal regeneration. This review provides an overview of adult human stem cells and their potential use in perio-dontal regeneration.

scholarly journals Fibroblast Growth Factor (FGF): A Review

2013 ◽  
Vol 01 (02) ◽  
pp. 091-094
Author(s):  
Ram Gupta ◽  
Manu Gupta ◽  
Avnika Garg
Keyword(s):  
Wound Healing ◽  
Growth Factors ◽  
Periodontal Regeneration ◽  
Fibroblast Growth Factors ◽  
Root Surface ◽  
Matrix Proteins ◽  
Fibroblast Growth ◽  
Polypeptide Growth Factors ◽  
Naturally Occurring ◽  
Periodontal Wound Healing

AbstractIn order for periodontal regeneration to occur, progenitor cells must migrate to the denuded root surface, attach to it, proliferate and mature into an organized and functional fibrous attachment apparatus. Significant advances have been made during the last decade in understanding the factors controlling the migration, attachment and proliferation of cells. A group of naturally occurring molecules known as polypeptide growth factors in conjunction with certain matrix proteins, are key regulators of these biological events. Of these, the fibroblast growth factors (FGFs) appear to have an important role in periodontal wound healing. The purpose of this review is to summarize current information on these growth factors with emphasis on their potential implications in periodontal wound healing and regeneration.

scholarly journals Regulating VEGF signaling in platelet concentrates via specific VEGF sequestering

2016 ◽  
Vol 4 (5) ◽  
pp. 819-825 ◽  
Author(s):  
David G. Belair ◽  
Ngoc Nhi Le ◽  
William L. Murphy
Keyword(s):  
Wound Healing ◽  
Growth Factors ◽  
Platelet Concentrates ◽  
Vegf Signaling

Platelets contain an abundance of growth factors that mimic the composition of the wound healing milieu, and platelet-derived VEGF in particular can negatively influence wound healing if unregulated.

Regenereation in periodontics

2018 ◽  
Author(s):  
Murtaza Kaderi ◽  
Mohsin Ali ◽  
Alfiya Ali ◽  
Tasneem Kaderi
Keyword(s):  
Tissue Engineering ◽  
Clinical Practice ◽  
Periodontal Disease ◽  
Disease Progression ◽  
Tissue Regeneration ◽  
Surgical Procedures ◽  
Periodontal Regeneration ◽  
Guided Tissue Regeneration ◽  
Periodontal Tissues ◽  
Extensive Documentation

The goals of periodontal therapy are to arrest of periodontal disease progression and to attain the regeneration of the periodontal apparatus. Osseous grafting and Guided tissue regeneration (GTR) are the two techniques with the most extensive documentation of periodontal regeneration. However, these techniques offer limited potential towards regenerating the periodontal tissues. Recent surgical procedures and application of newer materials aim at greater and more predictable regeneration with the concept of tissue engineering for enhanced periodontal regeneration and functional attachment have been developed, analyzed, and employed in clinical practice

Natural, Synthetic and their Combinatorial Nanocarriers Based Drug Delivery System in the Treatment Paradigm for Wound Healing Via Dermal Targeting

2020 ◽  
Vol 26 (36) ◽  
pp. 4551-4568
Author(s):  
Mohammad Kashif Iqubal ◽  
Sadaf Saleem ◽  
Ashif Iqubal ◽  
Aiswarya Chaudhuri ◽  
Faheem Hyder Pottoo ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Wound Healing ◽  
Photodynamic Therapy ◽  
Growth Factors ◽  
Combination Therapy ◽  
Healing Process ◽  
Wound Healing Process ◽  
Wound Site ◽  
Synthetic Drugs ◽  
Treatment Paradigm

A wound refers to the epithelial loss, accompanied by loss of muscle fibers collagen, nerves and bone instigated by surgery, trauma, frictions or by heat. Process of wound healing is a compounded activity of recovering the functional integrity of the damaged tissues. This process is mediated by various cytokines and growth factors usually liberated at the wound site. A plethora of herbal and synthetic drugs, as well as photodynamic therapy, is available to facilitate the process of wound healing. Generally, the systems used for the management of wounds tend to act through covering the ruptured site, reduce pain, inflammation, and prevent the invasion and growth of microorganisms. The available systems are, though, enough to meet these requirements, but the involvement of nanotechnology can ameliorate the performance of these protective coverings. In recent years, nano-based formulations have gained immense popularity among researchers for the wound healing process due to the enhanced benefits they offer over the conventional preparations. Hereupon, this review aims to cover the entire roadmap of wound healing, beginning from the molecular factors involved in the process, the various synthetic and herbal agents, and combination therapy available for the treatment and the current nano-based systems available for delivery through the topical route for wound healing.

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