scholarly journals Relevance of animal infections in SARS-Cov-2 spread: an update after 1 year of pandemic.

2021 ◽  
Author(s):  
Frazzini Sara ◽  
Amadori Massimo ◽  
Lauretta Turin ◽  
Federica Riva
Keyword(s):  
Animal Species ◽  
Natural Infection ◽  
Farm Animals ◽  
World Health ◽  
Chinese City ◽  
Experimental Infections ◽  
Novel Coronavirus ◽  
Health Organization ◽  
Therapy Studies

In December 2019, several cases of pneumonia caused by a novel Coronavirus, later identified as SARS-CoV-2, were detected in the Chinese city of Wuhan. Due to its rapid, worldwide spread, on 11 March 2020 the World Health Organization declared a pandemic state. Since this new virus is genetically similar to the coronaviruses of bats, it was thought to have a zoonotic origin. Within a year of the appearance of SARS-CoV-2, several cases of infection were also reported in animals, suggesting animal-to-human and animal-to-animal transmission within mammals. Natural infection has been found in both companion and captive animals such as lions, tigers and gorillas. Among farm animals, the only ones found to be susceptible to SARS-CoV-2 infection so far are minks. Experimental infections have documented the susceptibility to SARS-CoV-2 of several animal species, such as humanized mice, hamsters, cats, dogs, ferrets, racoon dogs, cattle and non-human primates. Experimental infections are crucial for both elucidation of the role of animals in transmission and development of appropriate animal models for pathogenesis and therapy studies. This review aims to update the knowledge on natural and experimental SARS-CoV-2 infections in animals.

Treatment Options in COVID-19: The Role of Bioavailable Antiviral Ribonucleoside Analog on NHC in vitro

2020 ◽  
Author(s):  
Lara Bittmann
Keyword(s):  
World Health Organization ◽  
Clinical Picture ◽  
Treatment Options ◽  
World Health ◽  
Wuhan City ◽  
The World ◽  
Novel Coronavirus ◽  
Health Organization

On December 31, 2019, WHO was informed of cases of pneumonia of unknown cause in Wuhan City, China. A novel coronavirus was identified as the cause by Chinese authorities on January 7, 2020 and was provisionally named "2019-nCoV". This new Coronavirus causes a clinical picture which has received now the name COVID-19. The virus has spread subsequently worldwide and was explained on the 11th of March, 2020 by the World Health Organization to the pandemic.

scholarly journals An Overview of SARS-CoV-2 and Animal Infection

2020 ◽  
Vol 7 ◽  
Author(s):  
Mohamed A. A. Mahdy ◽  
Waleed Younis ◽  
Zamzam Ewaida
Keyword(s):  
Intermediate Host ◽  
Animal Species ◽  
Experimental Studies ◽  
Short Review ◽  
World Health ◽  
Wholesale Market ◽  
Animal Infection ◽  
Rapid Spread ◽  
Novel Coronavirus ◽  
Health Organization

A novel coronavirus has been reported as the causative pathogen of the Coronavirus disease 2019 (COVID-19) outbreak in Wuhan city, China in December 2019. Due to the rapid spread of the virus worldwide, it has been announced as a pandemic by the World Health Organization (WHO). Hospitalized patients in Wuhan were associated with the Huanan seafood wholesale market where live animals, such as poultry, bats, snakes, frogs, rabbits, marmots, and hedgehogs are sold in that market which suggests a possible zoonotic infection. It was suggested that bat is the natural host of SARS-CoV-2, but the intermediate host is still unclear. It is essential to identify the potential intermediate host to interrupt the transmission chain of the virus. Pangolin is a highly suspected candidate as an intermediate host for SARS-CoV-2. Recently, SARS-CoV-2 infection has been reported in cats, dogs, tigers, and lions. More recently SARS-CoV-2 infection affected minks severely and zoonotic transfer with a variant SARS-CoV-2 strain evidenced in Denmark, Netherlands, USA, and Spain suggesting animal-to-human and animal-to-animal transmission within mink farms. Furthermore, experimental studies documented the susceptibility of different animal species to SARS-CoV-2, such as mice, golden hamsters, cats, ferrets, non-human primates, and treeshrews. It is also essential to know the possibility of infection for other animal species. This short review aims to provide an overview on the relation between severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infection and animals.

scholarly journals COVID-19: A Critical Review on Viral Biochemistry, Environmental Transmission, Therapeutics and Safety Measures

2020 ◽  
Vol 1 (6) ◽  
Author(s):  
Roshni Kumari ◽  
Kumari Pragati Nanda ◽  
Hena Firdaus ◽  
Soumen Dey
Keyword(s):  
Specific Treatment ◽  
Scattered Data ◽  
Review Article ◽  
World Health ◽  
The Novel ◽  
Safety Measures ◽  
Current Scenario ◽  
Novel Coronavirus ◽  
Health Organization

The outbreak of coronavirus disease caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is declared pandemic by World Health Organization (WHO) keeping in view its infection rate and toxicity level. The entire world is struggling hard to survive the prevailing health emergency. The authors realise the urgent need of contributing an overview of the present scenario to the researchers who are breathlessly trying to combat this pandemic situation. This review aimed at binding all the scattered data and research available till now on COVID-19 disease starting from its origin to transmission and spread through environmental factors till treatment and the safety measures that should be implemented. This article would possibly help the readers by providing an outlook of current scenario on various perspectives of COVID-19 disease at a single glance. The types, origin and toxicity caused are discussed in brief. The role of contaminated aerosols (viral-laden smoke from tobacco, cigarettes), wastewater, fomites, human and faecal matter are important in spreading the novel coronavirus in the environment. There is no specific treatment till date but clinical trials and diagnosis on several known drugs are on-going. The precaution and safety measures could hopefully reduce number of infections and mortality. The number of infected cases confirmed till 2 August 2020 was 17660523 with 680894 deaths in the world. We tried in this review article to summarize the scattered data available on biochemistry of SARS-CoV-2, environmental spread of virus and the safety measures to combat COVID-19 pandemic.

scholarly journals Role of nutrients regulation in the immune system in preventing COVID-19 infection: A brief review

2021 ◽  
Vol 13 (2) ◽  
pp. 760-765
Author(s):  
Anamika Chauhan
Keyword(s):  
Immune System ◽  
Age Groups ◽  
World Health ◽  
The Novel ◽  
Beneficial Effects ◽  
Coronavirus Infection ◽  
The Common ◽  
Novel Coronavirus ◽  
Health Organization

This review aimed to focus on using foods to boost immunity against COVID-19 in all age groups. In human, coronavirus causes the common cold, severe acute respiratory syndrome (SARS), and a major threat to public health. The novel coronavirus was declared a pandemic by the World Health Organization due to its rapid infectivity. COVID-19 infection is most probably reported in people with low immunity response. The nutrients, which show beneficial effects on the immune system, are called immune nutrients and diet is called immune diet. A healthy diet can reduce the risk of infection of COVID-19 and can prevent disease. Nutritional food intake is also necessary for people with chronic illness, obese persons, diabetes, cardiovascular disease, cognitive dysfunction like anxiety and depression. All nutrients are essential for maintaining immunity and providing appropriate amounts of protein, fat, carbohydrate, vitamins, and minerals for the surveillance mode of keeping us from getting sick. The use of plenty of water, minerals such as micronutrients, zinc, copper, selenium, iron, magnesium, food rich in vitamins, and a good lifestyle can promote health and overwhelm this coronavirus infection.

scholarly journals An Overview of SARS‐CoV‐2 and Animal Infection

2020 ◽  
Author(s):  
Mohamed Mahdy
Keyword(s):  
Animal Species ◽  
Short Review ◽  
World Health ◽  
Zoonotic Infection ◽  
Wholesale Market ◽  
Wuhan City ◽  
Animal Reservoir ◽  
Animal Infection ◽  
Novel Coronavirus ◽  
Health Organization

A novel coronavirus has been reported as the causative pathogen of the Coronavirus disease 2019 (COVID-19) outbreak Wuhan city, China in December 2019. Due to the rapid spreading of COVID-19 worldwide, it has been announced as a pandemic by the World Health Organization (WHO). Hospitalized patients in Wuhan are associated with the Huanan seafood wholesale market where live animals, such as poultry, bats, snakes, frogs, rabbits, marmots, and hedgehogs are sold in that market which suggests a possible zoonotic infection. Therefore, it is essential to identify the potential animal reservoir, and the possibility of infection for other animal species. This short review aims to provide an overview on the relation between severe acute respiratory syndrome coronavirus‐2 (SARS‐CoV‐2) infection and animals.

scholarly journals Role of Indian Youth in Keeping COVID - 19 at Bay : A Narrative Review

2020 ◽  
pp. 357-360
Author(s):  
Shraddha Kalyani ◽  
Rushi Somani
Keyword(s):  
Large Population ◽  
Geographical Area ◽  
World Health ◽  
Population Immunity ◽  
First Case ◽  
Infection Disease ◽  
Novel Coronavirus ◽  
Health Organization ◽  
International Boundaries

<p>A pandemic is defined as “an epidemic occurring worldwide, or over a very wide area, crossing international boundaries and usually affecting a large number of people”. The classical definition includes nothing about population immunity, virology or disease severity. As World Health Organization declared COVID-19 as pandemic in very beginning of year 2020. In COVID-19 CO stands for corona, 'VI' for virus, and 'D' for disease. Formerly, this disease was referred to as '2019 novel coronavirus' or '2019-nCoV.' The COVID-19 virus is a new virus linked to the same family of viruses as Severe Acute Respiratory Syndrome (SARS) and some types of common cold. First case in India was detected in the last week of January 2020. As India is second largest country in terms of population with less geographical area and COVID-19 is contagious infection disease it’s going to affect large population in India and affect different sectors such as specially health and financial sector. According to ‘2011 Census of India’ in India by next 10 years from 2011 number of young people will be more, that’s why what youngsters do in such situation will define our country’s future.</p>

scholarly journals The role of environmental factors on transmission rates of the COVID-19 outbreak: an initial assessment in two spatial scales

2020 ◽  
Vol 10 (1) ◽  
Author(s):  
Canelle Poirier ◽  
Wei Luo ◽  
Maimuna S. Majumder ◽  
Dianbo Liu ◽  
Kenneth D. Mandl ◽  
...  
Keyword(s):  
Environmental Factors ◽  
Spatial Scales ◽  
Influenza Viruses ◽  
Health Interventions ◽  
World Health ◽  
Initial Assessment ◽  
Novel Coronavirus ◽  
Health Organization ◽  
Support Decision Making

Abstract First identified in Wuhan, China, in December 2019, a novel coronavirus (SARS-CoV-2) has affected over 16,800,000 people worldwide as of July 29, 2020 and was declared a pandemic by the World Health Organization on March 11, 2020. Influenza studies have shown that influenza viruses survive longer on surfaces or in droplets in cold and dry air, thus increasing the likelihood of subsequent transmission. A similar hypothesis has been postulated for the transmission of COVID-19, the disease caused by SARS-CoV-2. It is important to propose methodologies to understand the effects of environmental factors on this ongoing outbreak to support decision-making pertaining to disease control. Here, we examine the spatial variability of the basic reproductive numbers of COVID-19 across provinces and cities in China and show that environmental variables alone cannot explain this variability. Our findings suggest that changes in weather (i.e., increase of temperature and humidity as spring and summer months arrive in the Northern Hemisphere) will not necessarily lead to declines in case counts without the implementation of drastic public health interventions.

scholarly journals Sequential use of hemadsorption using Cytosorb® and Biosky® filter- technology in a COVID-19 patient suffering from severe ARDS

2020 ◽  
Author(s):  
Matthias Mezger ◽  
Ingo Eitel ◽  
Stephan Ensminger ◽  
Dirk Pogorzalek ◽  
Zhipan Huang ◽  
...  
Keyword(s):  
Distress Syndrome ◽  
Fluid Management ◽  
Critical Discussion ◽  
World Health ◽  
The Novel ◽  
Case Presentation ◽  
The World ◽  
Novel Coronavirus ◽  
Health Organization

Abstract In March 2020, the World Health Organization (WHO) declared the novel coronavirus disease (COVID- 19) pandemic. Here, we present the case of a patient who was admitted to our hospital with acute respiratory distress syndrome (ARDS) following infection with COVID-19. After initial stabilization through restrictive fluid management, hemadsorption using Cytosorb® was performed and finally temporary extubation of the patient was possible. However, the patient again clinically deteriorated and needed ventilation and finally ECMO-support and high catecholamine application. Whilst being on VV- ECMO, hemadsorption using Biosky® MG 350 filter was performed. In this manuscript, after a brief overview of the role of hemadsorption in ARDS, a detailed case presentation is followed by a critical discussion of the current literature.

scholarly journals An Overview of SARS‐CoV‐2 and Animal Infection

2020 ◽  
Author(s):  
Mohamed Mahdy
Keyword(s):  
Animal Species ◽  
Short Review ◽  
World Health ◽  
Zoonotic Infection ◽  
Wholesale Market ◽  
Wuhan City ◽  
Animal Reservoir ◽  
Animal Infection ◽  
Novel Coronavirus ◽  
Health Organization

A novel coronavirus has been reported as the causative pathogen of the Coronavirus disease 2019 (COVID-19) outbreak Wuhan city, China in December 2019. Due to the rapid spreading of COVID-19 worldwide, it has been announced as a pandemic by the World Health Organization (WHO). Hospitalized patients in Wuhan are associated with the Huanan seafood wholesale market where live animals, such as poultry, bats, snakes, frogs, rabbits, marmots, and hedgehogs are sold in that market which suggests a possible zoonotic infection. Therefore, it is essential to identify the potential animal reservoir, and the possibility of infection for other animal species. This short review aims to provide an overview on the relation between severe acute respiratory syndrome coronavirus‐2 (SARS‐CoV‐2) infection and animals.

scholarly journals Canadian Society of Thoracic Radiology/Canadian Association of Radiologists Consensus Statement Regarding Chest Imaging in Suspected and Confirmed COVID-19

2020 ◽  
Vol 71 (4) ◽  
pp. 470-481 ◽  
Author(s):  
Carole Dennie ◽  
Cameron Hague ◽  
Robert S. Lim ◽  
Daria Manos ◽  
Brett F. Memauri ◽  
...  
Keyword(s):  
Consensus Statement ◽  
World Health ◽  
Canadian Society ◽  
Canadian Association ◽  
New Information ◽  
Reporting Structure ◽  
Novel Coronavirus ◽  
Health Organization ◽  
Key Questions

On March 11, 2020, the World Health Organization declared infection related to a novel coronavirus (SARS-CoV-2) a pandemic. The role and impact of imaging predates this declaration and continues to change rapidly. This article is a consensus statement provided by the Canadian Society of Thoracic Radiology and the Canadian Association of Radiologists outlining the role of imaging in COVID-19 patients. The objectives are to answer key questions related to COVID-19 imaging of the chest and provide guidance for radiologists who are interpreting such studies during this pandemic. The role of chest radiography (CXR), computed tomography (CT), and lung ultrasound is discussed. This document attempts to answer key questions for the imager when dealing with this crisis, such as “When is CXR appropriate in patients with suspected or confirmed COVID-19 infection?” or “How should a radiologist deal with incidental findings of COVID-19 on CT of the chest done for other indications?” This article also provides recommended reporting structure for CXR and CT, breaking diagnostic possibilities for both CXR and CT into 3 categories: typical, nonspecific, and negative based on imaging findings with representative images provided. Proposed reporting language is also outlined based on this structure. As our understanding of this pandemic evolves, our appreciation for how imaging fits into the workup of patients during this unprecedented time evolves as well. Although this consensus statement was written using the most recent literature, it is important to maintain an open mind as new information continues to surface.

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