scholarly journals The Relationship between Lateral Nasal Wall Collapse and Nasal Obstruction, a case-control study

2021 ◽  
Author(s):  
Yong Ju Jang ◽  
Mi Rye Bae ◽  
Woo Ri Choi
Keyword(s):  
Nasal Obstruction ◽  
Case Control Study ◽  
Lateral Nasal Wall ◽  
Skin Thickness ◽  
Nasal Valve ◽  
Control Groups ◽  
And Control ◽  
The Relationship ◽  
Valve Angle ◽  
Control Study

Objectives In clinical practice, lateral nasal wall collapse during forced inspiration is widely regarded as a sign of nasal obstruction or criterion indicating nasal valve surgery. This study aims to evaluate the relationship between the degree of lateral nasal wall collapse and subjective nasal obstruction. Design Case-Control study Setting Tertiary centre hospital Participants Case group consisted of 24 patients who had been diagnosed with a deviated nasal septum or nasal valve stenosis. Control group consisted of 27 volunteers with no nasal obstruction symptoms and no septal deviation on nasal endoscopy. Main outcome measures Lateral nasal wall collapse is determined by the degree of lateral nasal wall triangle (LNWT) area reduction on frontal view during forced inspiration compared to quiet inspiration. LNWT area ratio of the patient and control groups was compared. The relationship between the lateral nasal wall collapse and clinical factors including symptom scores, nasal valve angles, skin thickness were evaluated. Results The average LNWT area ratio of the patient (n=24) and control groups (n=27) was 0.96 and 0.83 respectively (p=0.001). Symptom score (NOSE and VAS) is not related to the degree of lateral nasal wall collapse. Moreover, nasal valve angle and skin thickness were also not related to the degree of lateral nasal wall collapse. In 14 of the 19 patients, the more obstructed side corresponded to the side of narrower nasal valve angle, and 5 were not. Conclusion Lateral nasal wall collapse is not related to a patients’ nasal obstruction.

Dietary diversity score is inversely related to the risk of polycystic ovary syndrome in Tehranian women: a case-control study

2021 ◽  
pp. 1-6
Author(s):  
Sahel Soodi ◽  
Seyed Ali Keshavarz ◽  
Sedighe Hosseini ◽  
Behnood Abbasi
Keyword(s):  
Polycystic Ovary Syndrome ◽  
Case Control Study ◽  
Dietary Diversity ◽  
Polycystic Ovary ◽  
Case Control ◽  
Control Groups ◽  
Ovary Syndrome ◽  
And Control ◽  
The Relationship ◽  
Control Study

Polycystic ovary syndrome (PCOS) is the most common endocrine disorder among women of reproductive age and is affected by various dietary factors. Therefore, this study aimed to investigate the relationship between dietary diversity score (DDS) and the risk of PCOS. Our case-control study was conducted in the summer and autumn of 2019 in Taleghani and Arash hospitals in Tehran, Iran. A total of 494 participants (203 cases and 291 controls) were included in the study. Thereafter, their demographic information, dietary intake, and anthropometric and physical activity assessments were gathered. A validated semi-quantitative food frequency questionnaire was then used to calculate the DDS by scoring 5 food groups. To evaluate the risk of PCOS in association with DDS, the subjects were categorized based on the quartile cut-off points of the DDS. The mean ± SD age of the participants in both the case and control groups was 28.98 ± 5.43 and 30.15 ± 6.21 years, while mean ± SD body mass index was 25.74 ± 5.44 and 23.65 ± 3.90 kg/m2, respectively. The comparison between the case and control groups indicated that total DDS was 5.19 ± 1.19 for the cases and 5.51 ± 1.19 for the controls. The comparison of DDS in the highest versus the lowest quartiles showed a decreased risk of PCOS (p < 0.05). We demonstrated an inverse association between DDS and PCOS compared with the control group. Furthermore, a higher DDS was significantly associated with a lower risk of PCOS (odds ratio = 0.40). Novelty: This is the first investigation on the relationship between DDS and PCOS. Results depicted an inverse relationship between DDS and PCOS.

Correlation Between CCND1 Gene Polymorphism and Genetic Susceptibility to Gastric Cancer in Chinese Population

2020 ◽  
Author(s):  
Huiwen Pan ◽  
Xuyu Gu ◽  
Chen Zou ◽  
Keping Chen ◽  
Yu Fan
Keyword(s):  
Gastric Cancer ◽  
Gene Polymorphism ◽  
Case Control Study ◽  
Control Groups ◽  
Ccnd1 Gene ◽  
Significant Difference ◽  
And Control ◽  
The Relationship ◽  
Normal Controls ◽  
Control Study

Abstract Objective: The relationship between Cyclin D1 gene (CCND1) rs9344 polymorphism and susceptibility to gastric cancer (GC) is investigated.Methods: In a case-control study, we selected 577 cases of GC from The People's Hospital Affiliated to Jiangsu University in China along with 678 normal controls. Blood DNA was extracted and PCR amplified, gene polymorphism was determined using Snapshot method.Results: Analysis reveals significant difference in smoking between GC and control groups (P=0.006), however, not on polymorphism (P＞0.05). Conclusion: Smoking is associated with gastric cancer, whereas CCND1 rs9344 polymorphism does not implicate susceptibility of gastric cancer.

scholarly journals Occupational stress and psychological health impact on hypertension of miners in noisy environment in Wulumuqi, China: a case-control study

2020 ◽  
Vol 20 (1) ◽  
Author(s):  
Yaoqin Lu ◽  
Huan Yan ◽  
Jiandong Yang ◽  
Jiwen Liu
Keyword(s):  
Risk Factor ◽  
Propensity Score ◽  
Occupational Stress ◽  
Psychological Health ◽  
Case Control Study ◽  
Case Control ◽  
Noisy Environment ◽  
Control Groups ◽  
And Control ◽  
Control Study

Abstract Background Hypertension has been declared as a global public health crisis by the World Health Organization, because of its high prevalence. It affects the health of one billion people worldwide and is directly responsible for the deaths of more than 10 million people per year. The purpose of our research was to explore the influence of occupational stress and psychological health on hypertension of miners who work in a noisy environment and provide decision reference for relevant departments to keep miners’ health. Methods A case-control study was carried out in this research. The study subjects were divided into case groups and control groups based on whether they had hypertension or not. Effort-Reward Imbalance questionnaire and Self-Reporting Inventory questionnaire were used to investigate the psychological health status and occupational stress of the target population. General information was balanced between case and control groups through propensity score matching method. After propensity score matching, a multifactorial analysis was used to explore the impact of occupational stress and psychological health on hypertension. Results According to the result of the multivariate analysis, psychological health was hazard to hypertension (t = 5.080, P<0.001) and occupational stress was not a direct risk factor for hypertension (t = 1.760, P = 0.080). The model was statistically significant (χ2 = 20.4, P<0.01). Conclusions For miners working in the noisy environment, psychological status was a direct risk factor to hypertension, while occupational stress was an indirect factor.

Hair nicotine concentration of cats with gastrointestinal lymphoma and unaffected control cases

2020 ◽  
Vol 186 (13) ◽  
pp. 414-414 ◽  
Author(s):  
Victoria Smith ◽  
Clare Knottenbelt ◽  
David Watson ◽  
Dominic J Mellor ◽  
Alexandra Guillen Martinez ◽  
...  
Keyword(s):  
Case Control Study ◽  
Control Group ◽  
Gastrointestinal Lymphoma ◽  
Control Groups ◽  
Nicotine Concentration ◽  
Hair Samples ◽  
Significant Difference ◽  
Unaffected Control ◽  
And Control ◽  
Control Study

BackgroundA previous study showed an association between owner-reported exposure to environmental tobacco smoke (ETS) and lymphoma in cats. This study aimed to investigate the association between ETS exposure and gastrointestinal lymphoma in cats, using hair nicotine concentration (HNC) as a biomarker.MethodsThis was a prospective, multi-centre, case–control study. Gastrointestinal lymphoma was diagnosed on cytology or histopathology. Hair samples were obtained from 35 cats with gastrointestinal lymphoma and 32 controls. Nicotine was extracted from hair by sonification in methanol followed by hydrophilic interaction chromatography with mass spectrometry. Non-parametric tests were used.ResultsThe median HNC of the gastrointestinal lymphoma and control groups was not significantly different (0.030 ng/mg and 0.029 ng/mg, respectively, p=0.46). When the HNC of all 67 cats was rank ordered and divided into quartiles, there was no significant difference in the proportion of lymphoma cases or controls within these groups (p=0.63). The percentage of cats with an HNC≥0.1 ng/mg was higher for the lymphoma group (22.9%) than the control group (15.6%) but failed to reach significance (p=0.45).ConclusionA significant association was not identified between HNC (a biomarker for ETS) and gastrointestinal lymphoma in cats; however, an association may exist and further studies are therefore required.

Association of influenza vaccination with reduced risk of venous thromboembolism

2009 ◽  
Vol 102 (12) ◽  
pp. 1259-1264 ◽  
Author(s):  
Tienan Zhu ◽  
Laure Carcaillon ◽  
Isabelle Martinez ◽  
Jean-Pierre Cambou ◽  
Xavier Kyndt ◽  
...  
Keyword(s):  
Venous Thromboembolism ◽  
Influenza Vaccination ◽  
Multivariate Regression ◽  
Case Control Study ◽  
Multivariate Regression Analysis ◽  
Case Control ◽  
Control Groups ◽  
And Control ◽  
Control Study ◽  
Reduced Risk

SummaryInfluenza vaccination can reduce the risk of cardiovascular events in patients with coronary heart disease, but its impact on the risk of venous thromboembolism (VTE) has not been studied. It was the aim of this study to investigate whether influenza vaccination reduces the risk of VTE. We conducted a case-control study involving 1,454 adults enrolled in 11 French centers between 2003 and 2007, comprising 727 consecutive cases with a first documented episode of VTE and 727 age- and sex-matched controls. In the case and control groups 202 (28.2%) and 233 (32.1%) subjects, respectively, had been vaccinated against influenza during the previous 12 months. After multivariate regression analysis, the odds ratios (OR) for VTE associated with vaccination were 0.74 (95% confidence interval [CI], 0.57–0.97) and 0.52 (95% CI, 0.32–0.85), respectively, for the whole population and for subjects aged 52 years or less. The protective effect of vaccination was similar for deep venous thrombosis (OR 0.9; 95% CI, 0.60–1.35) and pulmonary embolism (OR 0.71; 95% CI, 0.53–0.94) and for both provoked (OR 0.71; 95% CI, 0.53–0.97) and unprovoked VTE (OR 0.85; 95% CI, 0.59–1.23).This case-control study suggests that influenza vaccination is associated with a reduced risk of VTE.

scholarly journals Prevalence and components of metabolic syndrome in HIV-infected patients at the Tiko Central Clinic and Cottage Hospital in Cameroon

2020 ◽  
Vol 8 (10) ◽  
pp. 3481
Author(s):  
Vigny N. Njongang ◽  
Assob J. C. Nguedia ◽  
Ojong E. Walter
Keyword(s):  
Metabolic Syndrome ◽  
Abdominal Obesity ◽  
Case Control Study ◽  
Control Groups ◽  
Hiv Patients ◽  
High Blood Glucose ◽  
Low Hdl ◽  
And Control ◽  
Control Study ◽  
Apparently Healthy

Background: HAART and HIV related metabolic syndrome (MS) is associated with increased cardiovascular risk in aging HIV patients. This study was aimed at comparing the prevalence of MS between HIV-infected patients on HAART and apparently healthy HIV-uninfected individuals and identifying key MS components in these groups of subjects.Methods: This was a hospital-based case-control study. The cases were HIV sero-positive individuals on HAART for at least 6 months and controls were HIV sero-negative individuals.Results: 74/135 (54.8%) participants were females amongst which 53/75 (70.7%) and 21/60 (35%) were in the test and control groups respectively. The prevalence of MS was insignificantly higher in HIV-infected patients on HAART than in control subjects according to the IDF (22.7% versus 20%, p=0.834) and NCEP ATP III criteria (18.7% versus 18.3%, p=1.000) respectively. The most prevalent components of MS in HIV-infected patients on HAART were low HDL-c (100%), abdominal obesity (IDF: 68%, ATP III: 32%), and hypertension (28%). Multivariate analysis of MS components in HIV-infected patients on HAART revealed that hypertension (OR: 15.996, 95% CI: 3.385-75.585; p≤0.001) and high blood glucose (OR: 10.760, 95% CI: 1.642-70.505; p=0.013) were associated with MS. Significantly more HIV-infected females were seen with abdominal obesity than HIV-infected males (86.8% versus 4.5%, p≤0.001).Conclusions: Abdominal obesity is a driving component of MS in HIV-infected patients particularly among females and hypertension is a prevalent and predictor component of MS among HIV patients.

scholarly journals Assesment of Endometrial Vascularization with Immunohistochemical CD34 Assay in Recurrent Pregnancy Loss: A Case Control Study

2017 ◽  
pp. 1
Author(s):  
Emine Aydın ◽  
Taner Usta
Keyword(s):  
Pregnancy Loss ◽  
Recurrent Pregnancy Loss ◽  
Case Control Study ◽  
Transmembrane Protein ◽  
Vessel Diameter ◽  
Control Group ◽  
Control Groups ◽  
Significant Difference ◽  
And Control ◽  
Control Study

<p><strong>Objectives:</strong> We compared the endometrial vascularization in hysteroscopic endometrial samplings between recurrent pregnancy loss (RPL) and control group.</p><p><strong>Study Design:</strong> We prospectively evaluated hysteroscopic endometrial samplings from RPL and control groups. CD34 transmembrane protein was used for evaluating endometrial vascularization. The vascularization was assessed based on thickness of vessels, diameter of the largest vessel, and number of vessels per mm2 in CD34-stained slides.</p><p><strong>Results:</strong> There was no significant difference in demographic findings and vascularization, such as largest vessel diameter (p: 0.572), and number of vessels per mm2 (p: 0.982) between the two groups.</p><p><strong>Conclusion:</strong> The cycling endometrium is a highly angiogenic tissue and may play a role in the etiology of RPL. However, we find a weak relationship between endometrial vascularization and RPL.</p>

scholarly journals Prostate-specific antigen and (free prostate-specific antigen/ prostate-specific antigen) ratio in patients with Benign Prostatic Hyperplasia and Prostate Cancer

2020 ◽  
Vol 1 (01) ◽  
pp. 17-25
Author(s):  
Amal A. Hussein ◽  
Rayah S. Baban ◽  
Alaa G. Hussein
Keyword(s):  
Prostate Cancer ◽  
Prostate Specific Antigen ◽  
Case Control Study ◽  
Specific Antigen ◽  
Control Group ◽  
Inverse Association ◽  
Control Groups ◽  
Significant Difference ◽  
And Control ◽  
Control Study

Background: Prostate cancer is one of the most common cancers in menworldwide. Many markers are suggested as markers of prostate cancer with differentspecificity and sensitivity.Objective : The present study’s main aim is to examine the possible utility ofprostate-specific antigen indices as markers of prostate cancer.Methods: A case-control study was conducted in the Department of Chemistry andBiochemistry, College of Medicine, Al- Nahrain University, Baghdad, Iraq from July2018 till March 2019, includes 84 subjects divided into three groups:Twenty Four patients with prostate cancer (PCA), thirty patients with benignprostatic hyperplasia (BPH) and thirty healthy subjects as a control group wereexamined in this study.Thirty healthy volunteer subjects were asked to be involved in this study as a controlgroup. Blood samples from these patients were collected before obtaining a prostaticbiopsy. Serum PSA, fPSA levels were quantified by the ELISA technique.Results: PSA cut-off value was found to be more than 9.57 ng/ml for Prostate Cancerpatients, values range between 3.17 - 9.57 ng/ml for BPH patients and cut-off valuefor control was found to be less than 3.17 ng/ml, while serum (fPSA/PSA) % cut-offvalue was less than 11.1% for Prostate Cancer patients, values range between 11.1% -31 % for BPH patients, and cut-off value was greater than 31% for the control group.Conclusion: There is a highly significant difference in serum PSA levels and(fPSA/PSA)% between the prostate cancer and control groups. Body mass indexshowed an inverse association with the risk of prostate cancer.

A Case-Control Study on the p73 G4A Gene Polymorphism and Susceptibility to Breast Cancer in an Iranian Population

2020 ◽  
Author(s):  
Zeinab TAVAKKOL AFSHARI ◽  
Zahra GHOLIZADEH ◽  
Amin Reza NIKPOOR ◽  
Jalil TAVAKKOL AFSHARI ◽  
Rashin GANJALI ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Case Control Study ◽  
Case Control ◽  
Iranian Population ◽  
Control Group ◽  
Case Group ◽  
Medical Sciences ◽  
Control Groups ◽  
And Control ◽  
Control Study

Background: The tumor protein p73 (TP73) is a homolog of TP53 family. Ectopic p73 overexpression largely mimics p53 activities as a tumor suppressor and activates the transcription of p53-responsive genes and as a result induce apoptosis. This study aimed to investigate the association between p73 G4A polymorphism and the risk of breast cancer in a northeastern Iranian population. Methods: This case-control study was performed on 105 patients who admitted in educational hospitals of Mashhad University of Medical Sciences, Iran during 2013-2015, with breast cancer as case group and 120 healthy women as the control group. PCR-CTPP method was used to investigate the relationship between the p73 G4A polymorphism and the risk of breast cancer. Results: There was no significant association between the AA genotype of the p73 G4A polymorphism and breast cancer in case and control groups. Although G allele frequency was higher in the case group, the abundance of this allele between case and control groups was not statistically meaningful and, as a result, not associated with the risk of breast cancer in this study group. Conclusion: There was no association between G4A p73 polymorphism and the risk of breast cancer in a northeastern Iranian population.  

scholarly journals The Relationship Between Shiftwork and Violence Against Nurses: A Case Control Study

2017 ◽  
Vol 65 (12) ◽  
pp. 603-611 ◽  
Author(s):  
Steve Sun ◽  
Susan Goodwin Gerberich ◽  
Andrew D. Ryan
Keyword(s):  
Case Control Study ◽  
Case Control ◽  
Physical Assault ◽  
Work Related ◽  
Increased Risk ◽  
Multivariable Analyses ◽  
Nested Case Control ◽  
And Control ◽  
The Relationship ◽  
Control Study

This study investigated the potential relationship between shiftwork and work-related physical assault (PA) against nurses who are at high risk of violence globally. Nurses (6,300), randomly selected from the licensing database and working in Minnesota, were surveyed regarding PA experiences. Through a nested case-control study, nurses who reported a PA in the previous 12 months and controls who were randomly selected from their assault-free working months, respectively, identified exposures experienced during the month prior to the assault month (cases) and the random non-PA months (controls). Comparing case and control exposures, shiftwork was examined relevant to PA. Among 310 cases and 946 controls, most worked 8 hours or less (87%, 88%) during day shifts (44%, 70%). Multivariable analyses (odds ratios [ORs] and 95% confidence intervals [CIs]) revealed increased risk of PA for nurses working evening (OR = 1.55, 95% CI = [1.05, 2.27]), night (OR = 3.54, 95% CI = [2.31, 5.44]), and rotating day and evening (OR = 2.88, 95% CI = [1.22, 6.80]) shifts, which provides a basis for intervention opportunities.

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