scholarly journals Clinical and laboratory features of acute intestinal infections with hyemocolitis syndrome in children

2019 ◽  
Vol 11 (3) ◽  
pp. 54-60
Author(s):  
O. I. Klimova ◽  
N. V. Gonchar ◽  
L. A. Alekseeva ◽  
Yu. V. Lobzin
Keyword(s):  
Pearson Correlation ◽  
Correlation Coefficients ◽  
Urinary Infections ◽  
Intestinal Infections ◽  
Laboratory Features ◽  
Complicated Course ◽  
Group 2 ◽  
Severity Of The Disease ◽  
Inflammatory Changes ◽  
Group 1

The acute intestinal infections (AII) with a haemocolitis syndrome represent group of a serious illness at children that defines relevance of studying of their etiology and pathogenesis. The purpose of the work is to study the clinical and laboratory features of AII with hemocolitis syndrome depending on the etiology and complications. Materials and methods. Observed 77 patients of AII aged from 3 months up to 16 years. The etiological diagnosis verified using bacteriological and PCR studies of feces with AmpliSens® OKA screen-FL reagents and serological methods. Hemocolitis syndrome was observed in all patients. Patients with AII of a clarified etiology formed group 1 (n = 59), with AII of unclarified etiology – group 2 (n = 18). Intercurrent diseases were detected as non-specific complications of acute intestinal infections: respiratory (RI) and urinary infections (UI). AII severity was determined by the Clarke-index, the severity of dehydration – according to the WHO clinical scale. To evaluate the data of a research, the Mann-Whitney U-test and Pearson correlation coefficients were used. Results. There was a difference in the age of children in group 1 (3.9 ± 4.2 g) and group 2 (2.2 ± 2.6 g; p = 0.03) and in the frequency of complications: RI is diagnosed in group 1 for 54.5% of children, in group 2 for 83.3% (p=0.001); UI – at 45.5% and 16.7% respectively (p=0.03). In complicated course of AII, macroscopic signs of hemocolitis and inflammatory changes in the hemogram with the inclusion of platelet hemostasis in group 1 observed significantly more often than in group 2. In children of group 1, with uncomplicated acute intestinal infections, there was a significant correlation of signs of inflammation with dehydration and a higher severity of the disease according to the Clarke-index than with a complicated course. Conclusion. The age of children with AII of a clarified etiology was 3.9 ± 0.6 years, with AII of an unclarified etiology – 2.2 ± 0.6 years. AII of a clarified etiology preceded more hard, than AII of unclarified etiology. Complicated course of AII with hemocolitis syndrome characterized by expressiveness of signs of the local and system inflammatory answer.

The Effect of Examiner Social Behavior on Children’s Articulation Test Performance

1971 ◽  
Vol 14 (3) ◽  
pp. 659-672 ◽  
Author(s):  
Lawrence D. Shriberg
Keyword(s):  
Test Performance ◽  
Pearson Correlation ◽  
Correlation Coefficients ◽  
Social Behaviors ◽  
Second Grade ◽  
Experimental Conditions ◽  
Vocal Imitation ◽  
Group 2 ◽  
Test Retest Reliability ◽  
Group 1

Forty-eight first- and second-grade children with /r/ or /s/ errors met with an articulation examiner once a week for three consecutive weeks. During each session, the investigator role-played social behaviors of a supportive examiner (S) or a non-supportive examiner (N) (Relationship Segment) and then administered a Vocal Imitation Task and an imitative Articulation Task (Testing Segment). Subjects were divided into four groups balanced by sex, error sound, grade, and therapy experience. The sequence of experimental conditions for each group was Group 1 (SSS); Group 2 (NNN); Group 3 (SNS); and Group 4 (NSN). Two questions were posed: Do supportive versus nonsupportive examiner social behaviors affect articulation performance? Do differences in examiner social behaviors affect children’s test-retest reliability? No main or interaction effects for the type of examiner behaviors were obtained on either dependent variable. Comparison of the Pearson correlation coefficients for each group indicated that Group 1 obtained the highest temporal reliability, 0.92, while Groups 2, 3, and 4 obtained average coefficients of 0.67, 0.76, and 0.62, respectively. Clinical and theoretical implications of these data point to the value of using intensive designs for further study of interpersonal variables in the clinical process.

Relationship among anesthesia technique, surgical stress, and cognitive dysfunction following spinal surgery: a randomized trial

2019 ◽  
Vol 31 (6) ◽  
pp. 894-901 ◽  
Author(s):  
Anna A. Ezhevskaya ◽  
Alexei M. Ovechkin ◽  
Zhanna B. Prusakova ◽  
Valery I. Zagrekov ◽  
Sergey G. Mlyavykh ◽  
...  
Keyword(s):  
Cognitive Function ◽  
Pain Management ◽  
Epidural Analgesia ◽  
General Anesthesia ◽  
Cognitive Dysfunction ◽  
Postoperative Cognitive Dysfunction ◽  
Group 2 ◽  
Cellular Immune ◽  
Inflammatory Changes ◽  
Group 1

OBJECTIVESurgical trauma is known to result in systemic inflammatory changes that can lead to postoperative cognitive dysfunction. In the present study, the authors compared the effects of an epidural anesthesia protocol to those of traditional anesthesia with regard to postoperative inflammatory changes, cellular immunity, and cognitive dysfunction.METHODSForty-eight patients, ages 45–60 years, underwent multilevel thoracolumbar decompression and fusion and were randomly assigned to one of two groups: group 1 (27 patients) had combined epidural and general anesthesia, followed by epidural analgesia for 48 hours after surgery, and group 2 (21 patients) had general anesthesia, followed by traditional opioid pain management after surgery. At multiple time points, data on pain control, cognitive function, cellular immunity, and inflammatory markers were collected.RESULTSGroup 1 patients demonstrated lower pain levels, less systemic inflammation, less cellular immune dysfunction, and less postoperative cognitive dysfunction than group 2 patients.CONCLUSIONSThe use of combined epidural and general anesthesia followed by postoperative epidural analgesia during the first 48 hours after multilevel thoracolumbar decompression and fusion surgery had a significant positive effect on pain management, cellular immune function, systemic inflammation, and postoperative cognitive function.Clinical trial registration no.: 115080510080 (http://rosrid.ru)

scholarly journals Aortic and Internal Carotid Atherosclerosis in Patients with Carotid Stenosis: Semiautomatic Volumetric Analysis of Low-Attenuation Plaque on Curved Planar Reformations Using MDCT Angiographic Data

2019 ◽  
Vol 2019 ◽  
pp. 1-7
Author(s):  
Hiroshi Manaka ◽  
Izumi Torimoto ◽  
Zenjiro Sekikawa ◽  
Keiichiro Kasama ◽  
Tetsuya Yamamoto ◽  
...  
Keyword(s):  
Aortic Arch ◽  
Internal Carotid ◽  
Correlation Coefficients ◽  
Volumetric Analysis ◽  
Plaque Volume ◽  
Angiographic Data ◽  
Group 2 ◽  
Ica Stenosis ◽  
The Impact ◽  
Group 1

This retrospective study included 65 patients who underwent multidetector computed tomography (MDCT) carotid angiography; 28 patients were <70 years old (group 1), and 37 were ≥70 years old (group 2). Each low-attenuation (<30 Hounsfield units [HU]) plaque volume (LPV) and total uncalcified plaque volume ([TUPV] ≤150 HU) were semiautomatically measured on each aortic arch and internal carotid artery (ICA) curved planar reformations (CPR), using MDCT angiographic data. Correlation coefficients were employed to assess the impact of each plaque volume on various factors including ICA stenosis. The correlations (r > 0.5) were observed between aortic LPV and each ICA stenosis ratio and >30% stenosis in group 1, between aortic TUPV and male gender in group 1, and between ICA-TUPV and each aortic TUPV or the largest plaque thickness in group 2. Marginal correlations were observed between hyperlipidemia and aortic LPV and ICA-TUPV in group 1. There was no association between cerebral infarction and the aortic and ICA plaques. Both the aortic arch and ICA plaque volumes can be measured clinically. The increasing aortic LPV may be a significant factor associated with the development of ICA stenosis in patients younger than 70 years old.

scholarly journals Inflammatory changes in the placenta in ischemic-cervical insufficiency

2021 ◽  
Vol 20 (3) ◽  
pp. 33-37
Author(s):  
V. F. Dolgushina ◽  
E. S. Alikhanova ◽  
M. V. Astashkina ◽  
L. A. Smolnikova
Keyword(s):  
Pregnant Women ◽  
Umbilical Cord ◽  
Sampling Method ◽  
Fetal Membranes ◽  
Cervical Insufficiency ◽  
Continuous Sampling ◽  
Ascending Infection ◽  
Group 2 ◽  
Inflammatory Changes ◽  
Group 1

Introduction. The high frequency of inflammatory changin the placenta in isthmic-cervical insufficiency may be primarily associated with an ascending infection as a result of a violation of the barrier function of the cervix, however, premature remodeling of the cervix may also be secondary due to an already existing process. The study of the features of the spread of the infectious process and thnature of the inflammatory reaction in various structures of the placenta and fetal membranes can contribute to the understanding of pathogenetic mechanisms of preterm birth in isthmic-crvical insufficiency. Aim of the study — to evaluate the frequency and structure of inflammatory changes in the placenta in women with isthmic-cervical insufficiency. Materials and methods. A prospective cohort study was conduct, which included 154 pregnant women taken by the continuous sampling method. All patients were divided into two groups: group 1 consisted of 100 pregnant women with isthmic-cervical insufficiency, group 2 — pregnant women without isthmic-cervical insufficiency. All women after childbirth underwent a pathomorphological examination of the afterbirth. Results and discussion. In women with isthmic-cervical insufficiency, inflamatory changes in the placenta were detected in 71% (71) of cases, which was significantly more frequent compared to group 2 — 38.9% (21). Membranitis was significantly more frequent in isthmic-cervical insufficiency, amounting to 16% (16) versus 3.7% (2) comparison group (OR=4.32, 95% СI=1.03-18.09, p=0.023). Chorioamnionitis was 6 times more common in the afterbirth in women of group 1, accounting for 12% (12), versus 1.9% (1) in group 2 (OR=6.48, 95% CI=0.87-48.51, p=0.031). Involvement of the umbilical cord in the inflammatory process occurred only in pregnant women with isthmic-cervical insufficiency: funiculitis was combined with membranitis in 4% (4) of cases (p=0.137), the combination of funiculitis with choriomnionitis was detcted in 7% (7) of women p=0.047). Conclusion. The frequencof detection of inflammatory changes in the placenta in ICN was 71% (71). In the structure of inflammatory changes of the afterbirth in patients with ICN, the defeat of the fetal membranes prevails, which may indicate a predominatly ascending path of infection in this pathology. Damage membranes prevails, which may indicate a predominatly ascending path of infection in this pathology. Damage to the umbilical cord in ICN can occur both wth total inflammation of all structures of the placenta, and directly through the fetal membranes, without involving the chorion in the process.

Effektivität der Sklerosierungstherapie in Abhängigkeit vom Alter der Patienten

Phlebologie ◽  
2010 ◽  
Vol 39 (04) ◽  
pp. 202-207
Author(s):  
K. Denk ◽  
D. Schliephake ◽  
A. Recke ◽  
B. Kahle
Keyword(s):  
Elderly Patients ◽  
Varicose Veins ◽  
Pearson Correlation ◽  
Compression Therapy ◽  
Injection Sclerotherapy ◽  
Aesthetic Outcome ◽  
Efficient Treatment ◽  
Significant Difference ◽  
Group 2 ◽  
Group 1

SummaryIn clinical practice sclerotherapy of intradermal varicose veins seems to be more effective in elderly patients. Patients, methods: After prior duplex-sonographic investigation 48 patients with intradermal varicose veins (diameter 1–2 mm, C1,EP, AS, PR) were included. 24 patients (group 1) received Polidocanol (0.25% Aethoxysklerol®) injection sclerotherapy and 24 patients (group 2) received sodium chloride injections. In all subjects an area of 100 square centimetres of the lower limb was treated. The borders of each area were marked and photo documented. The injections were performed by an examiner who was unaware of which liquid had been injected. Compression therapy was performed for one week after the treatment. One and four weeks later the results were controlled by the physician who performed the injections and documented by an independent photographer. The glossy prints of the areas before and four weeks after the treatment were sent to two blinded independent external reviewers. The reviewers noted their evaluation on a visual analogue scale (VAS). The reviewers received each anonymous photodocument twice within 3 weeks. Results: The VAS of both experts showed a significant difference between the results in group 1 and group 2 (p < 0.0001). Median of efficacy was 58.5% in group 1 (verum) and 0.5% in group 2 (placebo). Both experts had a stable intraindividual reliability of 85% and further both raters didn´t differ concerning their ratings. In group 1 (verum) the Pearson correlation coefficient showed a significant correlation between the therapeutic outcome and the age of the treated patients. Conclusions: Injection sclerotherapy of intradermal varicose veins using 0.25 %Polidocanol (Aethoxysklerol) is an efficient treatment that leads to a good aesthetic outcome. In elderly patients sclerotherapy is more efficient.

Abstract 13730: Electrical Axes of P and T but Not QRS Waves on ECG Are New Indicators of Successfulness of the Nuss Operation for Pectus Excavatum Considering Anatomical Severity as Indicated by the Haller Index Acquired by CT

Circulation ◽  
2020 ◽  
Vol 142 (Suppl_3) ◽  
Author(s):  
Nobusada FUNABASHI ◽  
Yoshio Kobayashi
Keyword(s):  
Pectus Excavatum ◽  
Correlation Coefficients ◽  
P Wave ◽  
Invasive Technique ◽  
P Waves ◽  
Haller Index ◽  
Before And After ◽  
Group 2 ◽  
Group 1 ◽  
T Waves

Introduction: Pectus excavatum (PEX) is a depression of the sternum which can physically constrict the heart and cause abnormal ECGs. The Nuss operation is a minimally invasive technique for PEX repair. Hypothesis: As right (RA) and left atria (LA) are compressed in PEX, axes of P, QRS, and T waves are abnormal and the Nuss operation normalizes them. We also took the Haller index (HI) into to account. Methods: 17 PEX patients (14 male, 12±6 years) underwent CT and ECG before and after the Nuss operation. Results: All Nuss operations were successful, and HI was significantly improved from 5.62±2.29 to 3.29±0.65 (P=0.0002). There were no significant differences before and after surgery for electrical axes of P waves (46±20 vs 65±55, P=0.20), and QRS waves (75±33 vs 76±23, P=0.72), but T waves were greater thereafter (22±27 vs 40±19, P=0.001). Correlation coefficients (CC) between the degree of axes of P, QRS and T waves, and HI before operation were -0.23, -0.06, and 0.11, respectively. These values after operation were -0.25, -0.06, and 0.19, respectively. As HI is an indirect indicator of heart compression, we evaluated the degree of RA and LA compression qualitatively as none, mild, and moderate/more. Of 17 patients, 5 had moderate/more compression of RA and/or LA by PEX (group 1); the remaining 12 did not show compression (group 2). Only P wave values were significantly smaller in group 1 than 2 before surgery, but these differences disappeared after surgery. In both groups, degree of axes of T waves was significantly greater after the operation. Conclusion: In patients with PEX, axes of T waves after the Nuss operation became significant greater than before the operation in patients with moderate or more compression of RA and/or LA by PEX. For P waves, this was smaller before the operation in those with compression but this was improved by the Nuss operation. P and T wave axes but not QRS could be therefore non-invasive indicators of Nuss operation success in addition to gross PEX appearance.

scholarly journals 3D biometrics for hindfoot alignment using Weight Bearing CT

2018 ◽  
Vol 3 (3) ◽  
pp. 2473011418S0032
Author(s):  
Francois Lintz ◽  
Shu Zhang ◽  
Alessio Bernasconi ◽  
Jianzhong Zhang
Keyword(s):  
Interobserver Reliability ◽  
Weight Bearing ◽  
Intraclass Correlation ◽  
Correlation Coefficients ◽  
Continuous Series ◽  
Hindfoot Alignment ◽  
Group 3 ◽  
Group 2 ◽  
Weightbearing Ct ◽  
Group 1

Category: Hindfoot Introduction/Purpose: Hindfoot alignment is an important reference for foot and ankle surgery, and the Foot Ankle Offset (FAO) using semi-automatic software has been reported as a valuable hindfoot alignment measurement in weightbearing CT(WBCT). The objective was to assess the clinical relevance and reproducibility of the FAO value for hindfoot alignment and compare it with previous findings. Methods: A prospective study was conducted, with ethics committee approval. Patients were included, clinically examined and divided into 3 groups: normal alignment (Group 1), valgus (Group 2), varus (Group 3). A continuous series of 140 feet (71 patients) were referred from September to December 2017 (65 normal, 41 valgus, and 34 varus). All patients had a bilateral weight bearing CT, and the FAO values were recorded. The long axial view angle(HAct)was measured on Digitally Reconstructed Radiographs (DRR) as comparison. All values were measured and compared by two different investigators. The reproducibility of FAO and HAct were calculated using intraclass correlation coefficients(ICCs) and regression analysis was conducted to study the correlation between the two methods. Results: In Group 1, the mean value for FAO/HAct was 1.69%±2.58%/4.13±2.67, in Group 2, the FAO/HAct was 7.46%±3.18%/9.00±3.43; in Group 3 the values were -6.11%±4.55%/-7.49±6.06. The intra- and interobserver reliability were 0.991/0.992 and 0.976/0.976. There was a good linear correlation between HAct and FAO (R2=0.778, and the regression slope was 1.083. Conclusion: The use of weightbearing CT can help characterize hindfoot alignment objectively using WBCT. The present study is the first prospective comparative assessment of this technology and shows that FAO has good repeatability, and it correlates well with clinical examination,, X ray findings and previous literature. The FAO is a clinically relevant and reproducible method for measuring hindfoot alignment.

scholarly journals Correlation between Intraocular Pressure and Thickness of Extraocular Muscles, the Severity and Activity of Thyroid-associated Orbitopathy

Folia Medica ◽  
2019 ◽  
Vol 61 (1) ◽  
pp. 90-96
Author(s):  
Nina Staneva Stoyanova ◽  
Marieta Konareva-Kostianeva ◽  
Vesela Mitkova-Hristova ◽  
Irina Angelova
Keyword(s):  
Intraocular Pressure ◽  
Extraocular Muscles ◽  
Ocular Motility ◽  
Group 4 ◽  
Group 6 ◽  
Group 3 ◽  
Group 5 ◽  
Group 2 ◽  
Severity Of The Disease ◽  
Group 1

Abstract Aim: To establish the correlation between intraocular pressure (IOP) and thickness of extraocular muscles (EOM), the severity and activity of thyroid-associated orbitopathy (TAO). Materials and methods: 50 patients with TAO were included in the study. They all underwent a thorough ophthalmic examination, Goldmann tonometry (mm Hg) and computer tomography of the orbits, the muscle thickness sum (MTS) of each eye being measured in millimeters. According to the activity of TAO, the patients were divided into two groups – with and without activity, and according to the severity of the disease – into 6 groups: Group 1 (‘O’) had only subjective symptoms, group 2 (‘S’) had soft tissue symptoms, group 3 (‘P’) – proptosis, group 4 (‘E’) – ocular motility disorders, group 5 (‘C’) – corneal damage, and group 6 (‘Si’) – visual impairment; Results: TAO activity was registered in 21 patients (42 eyes, 42%) with MTS 23.39±3.81 and IOP 18.43±4.16. Twenty-nine patients (58 eyes, 58%) with MTS 19±3.21 and IOP 15.98±4.59 showed no TAO activity. The IOP within the groups, in terms of severity, was as follows: group 1 – 19.92+4.05; group 2 – 14.5±2.55; group 3 – 18.04±4.51; group 4 – 18.2±5.05; group 5 – 20.5±4.5; group 6 – 21.5±4.95. A correlation between the IOP and MTS was found. Conclusions: The IOP in patients with TAO depends on the thickness of the EOM, as well as on the activity and severity of the disease.

scholarly journals Specifics of the Attitude of Students with Deviant Behaviour to School Mediation Service

2020 ◽  
pp. 1517-1528
Author(s):  
Olga O. Andronnikova ◽  
Olga E. Radzikhovskaya
Keyword(s):  
Interpersonal Skills ◽  
Pearson Correlation ◽  
Effective Means ◽  
High Sensitivity ◽  
Deviant Behaviour ◽  
Mediation Effects ◽  
Self Development ◽  
The Difference ◽  
Group 2 ◽  
Group 1

This article discusses the perception of the effectiveness of school mediation services by adolescents with deviant behaviour. The research was based on Russian speaking adolescents aged 13-17 years (128 interviewees, including 78 girls and 50 boys). The questionnaire was developed in compliance with similar researches using expert evaluation. The results of the research are analyzed as per the Pearson correlation coefficient. The analysis of the difference in the perception of the effectiveness of mediation practices by a group directly involved in the implementation of mediation practices (group 2 of 40 persons) and a group with no direct experience of mediation (group 1 of 88 persons) resulted in some conclusions. The participants of group 2 consider the mediation method an effective means of resolving conflicts, increasing interpersonal skills, and respect for the interlocutor. Mediation is also an effective means of self-development and self-understanding for group 2. Group 1 displays infantile expectations of mediation effects and high sensitivity to fairness

scholarly journals Acute effect of COVID-19 pandemic on urological consultations and urological surgery

2021 ◽  
Author(s):  
Mehmet Çağlar Çakıcı ◽  
Ayberk İplikçi ◽  
Özgür Efiloğlu ◽  
Gökhan Atış ◽  
Asıf Yıldırım
Keyword(s):  
Emergency Service ◽  
Healthcare Facility ◽  
Acute Effect ◽  
Similar Distribution ◽  
Urological Surgery ◽  
First Case ◽  
Urinary Infections ◽  
Tertiary Healthcare ◽  
Group 2 ◽  
Group 1

Abstract Objective: Coronavirus disease (COVID-19) has greatly affected the clinical functioning of all sub-specialties, including urology. Clinicians have also been affected by this sudden chaotic process to a certain extent. In this study, we aimed to evaluate the effect of pandemic period on urological consultations and urological surgery in the acute phase of our country. Material and Methods: This retrospective study was designed after the approval of our hospital’s local ethics committee (decision number dated 22.07.2020: 2020/0458) was obtained. In the first 4 weeks after the first case in our country, the data of the patients who were consulted to the Urology clinic from the emergency service and other clinics in our hospital, which is a tertiary healthcare facility (Group 1), and patients in the same period of 2019 (group 2) were retrospectively collected. The demographic characteristics of the patients, specific triage evaluations for the pandemic, reasons for consultation and results were analyzed in detail. Results: Of the total 377 patients, 123 (32.6%) were in Group 1, and 254 (67.4%) were in Group 2. While there was a similar distribution in the number of weekly consultations in group 2, a statistically significant decrease was observed in the second and third weeks in Group 1 and an increase in the fourth week (p = 0.025). Ninety-three patients (75.6%) in Group 1 and 180 patients (70.9%) in Group 2 were consulted from the emergency service (p = 0.116). The two most common reasons for consultation were urinary infections and urolithiasis in Group 1; urolithiasis and hematuria in Group 2 (p = 0.027). While the rate of urological surgical intervention was 24.4% in Group 1; it was 37.8% in Group 2 (p = 0.010). Conclusion: The difficulty of the COVID-19 outbreak for clinicians has been to strike a balance between providing the most appropriate treatment while avoiding contamination for themselves and their patients. This balance in urology practice has emerged as a decrease in the rate of consultations resulting in surgery. Keywords: consultation, coronavirus, COVID-19, pandemic, urological surgery

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