scholarly journals Understanding the relevance of pain, depression and anxiety-like manifestations in the management of cystic fibrosis

2015 ◽  
Vol 67 (3) ◽  
pp. 1067-1070
Author(s):  
Evelina Moraru ◽  
Ramona Diaconu ◽  
Emil Anton ◽  
Laura Bozomitu ◽  
Carmen Anton ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Risk Factors ◽  
Cystic Fibrosis ◽  
Genetic Disease ◽  
Autosomal Recessive ◽  
Clinical Manifestations ◽  
Original Data ◽  
Epidemiological Studies ◽  
Depression And Anxiety

Cystic fibrosis (CF) is the most frequent autosomal recessive genetic disease in Caucasians. Although epidemiological studies continue to provide data and information that could lead to a better understanding of the clinical manifestations of the disease, there are still many controversies regarding the importance of some risk factors, such as pain, depression or anxiety in the pathogenesis of this disorder and its management. In the present study, we focused on the relevance of these 3 factors in the management of CF and to their related mechanisms in this disorder. Our original data showed that pain, depression and anxiety, determined by using a specific quality of life (KINDL) questionnaire, are important in understanding this disorder, the effectiveness of treatment and could also represent important factors for improving treatment. The screening and treatment of these specific manifestations in CF patients is recommended and holds promise for improving the outcome of patients with CF.

scholarly journals Stigma and cystic fibrosis

2010 ◽  
Vol 18 (1) ◽  
pp. 139-142 ◽  
Author(s):  
Tainá Maues Peluci Pizzignacco ◽  
Débora Falleiros de Mello ◽  
Regina Aparecida Garcia de Lima
Keyword(s):  
Quality Of Life ◽  
Cystic Fibrosis ◽  
Chronic Disease ◽  
Children And Adolescents ◽  
Treatment Adherence ◽  
Family Relationships ◽  
Life Histories ◽  
Autosomal Recessive ◽  
Family Members

Cystic Fibrosis (CF), also known as Mucoviscidosis, is a chronic disease of autosomal recessive origin and so far incurable. This analysis considers some characteristics of patients and family members that indicate it is a stigmatizing disease. The CF stigma’s impact on the lives of children and adolescents can affect treatment adherence, socialization, family relationships and the formation of their life histories, with direct consequences on their quality of life.

Clinical manifestations, risk factors and quality of life in patients with pitted keratolysis: a cross-sectional study in cadets

2018 ◽  
Vol 179 (5) ◽  
pp. 1220-1221 ◽  
Author(s):  
S. Bunyaratavej ◽  
C. Leeyaphan ◽  
P. Chanyachailert ◽  
P. Pattanaprichakul ◽  
P. Ongsri ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Risk Factors ◽  
Clinical Manifestations ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Cross Sectional

scholarly journals Depression and anxiety in cystic fibrosis: relation with quality of life

2010 ◽  
Vol 9 ◽  
pp. S97
Author(s):  
G. Olveira ◽  
C. Olveira ◽  
F. Espíldora ◽  
D. Antonio ◽  
A. Padilla ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Cystic Fibrosis ◽  
Depression And Anxiety

scholarly journals Neurobiology of Depression and Anxiety in Parkinson's Disease

2011 ◽  
Vol 2011 ◽  
pp. 1-5 ◽  
Author(s):  
Osamu Kano ◽  
Ken Ikeda ◽  
Derek Cridebring ◽  
Takanori Takazawa ◽  
Yasuhiro Yoshii ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Risk Factors ◽  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Clinical Features ◽  
Motor Symptoms ◽  
Depression And Anxiety ◽  
Neurochemical Changes ◽  
Premotor Phase

Depression and anxiety are common in Parkinson's disease (PD) and have important consequences on quality of life. These have long been recognized as frequent accompanying syndromes of PD, and several reports suggest that these are the causative process or risk factors that are present many years before the appearance of motor symptoms. The neurochemical changes in PD involving dopamine, norepinephrine, and serotonin might be related to the pathophysiology of depression and anxiety, but this is still not clear. Several studies showed that anxiety in PD patients occurs earlier than depression, during premotor phase, suggesting that there may be a link between the mechanisms that cause anxiety and PD. Whereas a recent study reported that PD patients with depression and anxiety were associated with different demographic and clinical features.

scholarly journals Predisposing Factors for Sexual Dysfunction in Multiple Sclerosis

2021 ◽  
Vol 12 ◽  
Author(s):  
Patrick Altmann ◽  
Fritz Leutmezer ◽  
Katharina Leithner ◽  
Tobias Monschein ◽  
Markus Ponleitner ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Risk Factors ◽  
Multiple Sclerosis ◽  
Sexual Dysfunction ◽  
Depression Scale ◽  
Cross Sectional Study ◽  
Depression And Anxiety ◽  
Cross Sectional ◽  
Anxiety Screening

Sexual dysfunction (SD) in people with multiple sclerosis (pwMS) has a detrimental impact on individual health-related quality of life (HRQoL). It is not clear whether SD in multiple sclerosis (MS) is an independent symptom or merely a byproduct of other symptoms such as depression or anxiety. This cross-sectional study of 93 pwMS determines risk factors for SD in MS based on prevalence, HRQoL, and associated disease outcomes. Diagnosis of SD was determined based on the Multiple Sclerosis Intimacy and Sexuality Questionnaire-19 (MSISQ-19) and correlated with physical disability (measured by Expanded Disability Status scale, EDSS), depression and anxiety [Hospital Anxiety and Depression Scale (HADS)], and HRQoL [Multiple Sclerosis Quality of Life-54 (MSQoL-54)]. Multivariate regression models were performed to determine independent risk factors for SD in pwMS. Almost half of the participants in this study (46%) reported SD. HRQoL was significantly poorer in patients with MS suffering from SD (median [IQR] MSQoL-54 scores: physical subscale 52 [41–68] vs. 81 [69–89], p < 0.001; mental subscale 50 [38–82] vs. 86 [70–89], p < 0.001). In the multivariate model, EDSS was the only independent risk factor for SD (OR 18.1 for EDSS ≥4 [95% CI 3.3–31.4, p < 0.001]), while depression and anxiety were not. We conclude that the risk for SD is growing with increasing EDSS and is independent of depression or anxiety. Screening for SD becomes particularly relevant in patients with growing disability.

scholarly journals A Longitudinal Study on the Prevalence and Risk Factors for Depression and Anxiety, Quality of Life, and Clinical Outcomes in Incident Peritoneal Dialysis Patients

2019 ◽  
Vol 39 (1) ◽  
pp. 74-82 ◽  
Author(s):  
Maggie M.Y. Mok ◽  
Carmen K.M. Liu ◽  
Man Fai Lam ◽  
Lorraine P. Y. Kwan ◽  
Gary C.W. Chan ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Risk Factors ◽  
Peritoneal Dialysis ◽  
Clinical Outcomes ◽  
World Health ◽  
First Year ◽  
Depression And Anxiety ◽  
Younger Age

Background Starting dialysis is an important life event. The prevalence and evolution of psychological symptoms at commencement of long-term dialysis is unclear. We examined the prevalence of and risk factors for depression and anxiety, and the quality of life (QOL) of incident peritoneal dialysis (PD) patients, and also the change of these parameters in the first year of PD in relation to clinical outcomes under the PD-first policy. Methods All patients commencing long-term PD from March 2011 to April 2015 were asked to complete the Hospital Anxiety and Depression Scale (HADS), World Health Organization Quality of Life-BREF and the Kidney Disease Quality of Life Instrument Short Form questionnaire. Patient demographics and the incidence of hospitalization, peritonitis, exit-site infection, and all-cause mortality were studied. The HADS was repeated after 9 – 12 months. Results A high depression score was present in 39.6% of 191 patients at commencement of PD and was more common in diabetes patients (odds ratio [OR] 2.03, 95% confidence interval [CI] 1.09 – 3.81). A high anxiety score was present in 23.6%, and the risk factors included younger age (OR 0.96 per year, 95% CI 0.94 – 0.99) and diabetes (OR 2.59, 95% CI 1.20 – 5.57). Both high depression and anxiety scores were associated with an inferior QOL, overall and across most QOL domains. Depression and anxiety symptoms did not change in the first year of PD and were not associated with short-term clinical outcomes. Conclusions High depression and anxiety scores were prevalent in incident PD patients where PD-first policy is adopted and were associated with inferior QOL. There was no improvement after 1 year of PD. The impact of strategic interventions targeting patient groups at risk such as those with diabetes or of younger age warrants further investigation.

scholarly journals Adult cystic fibrosis care in the 21st century

2015 ◽  
Vol 75 (3) ◽  
Author(s):  
E. Garattini ◽  
D. Bilton ◽  
G. Cremona ◽  
M. Hodson
Keyword(s):  
Quality Of Life ◽  
Cystic Fibrosis ◽  
Life Expectancy ◽  
21St Century ◽  
Autosomal Recessive ◽  
Therapeutic Strategies ◽  
Complex Care ◽  
Inherited Disease ◽  
Appropriate Care

Cystic fibrosis (CF) is the most common autosomal recessive inherited disease of Caucasian populations. As a result of a variety of diagnostic and therapeutic strategies there has been a dramatic increase in the life expectancy of patients with CF in the last decades and 50% of patients are now adults. This review will focus on the disease in adults and the provision of appropriate care. The complex care required to improve the survival and quality of life in the adult patients can best be provided in a dedicated adult cystic fibrosis unit. These units currently exist in many European countries, but more are needed in Italy.

scholarly journals The spectrum of sensitization of children with cystic fibrosis

2019 ◽  
pp. 89-92
Author(s):  
E. A. Antonova ◽  
A. V. Goryainova ◽  
S. Yu. Semykin ◽  
T. A. Filatova
Keyword(s):  
Quality Of Life ◽  
Cystic Fibrosis ◽  
Genetic Diseases ◽  
Clinical Manifestations ◽  
Public Health Problem ◽  
Allergic Diseases ◽  
Diet Therapy ◽  
Hereditary Disease ◽  
Global Public Health

Cystic fibrosis is a hereditary disease that affects the quality of life of patients without proper treatment. It has been established that allergic diseases have become a global public health problem. Due to a variety of clinical manifestations that affect the development, health and quality of life, it is difficult to diagnose. Due to the high incidence of allergic problems, there is the problem of interrelationship of hereditary genetic diseases - cystic fibrosis and spectral sensitization of children suffering from morbidity in order to improve the algorithms, improve the condition and quality of life of patients, due to the appointment of proper diet therapy.

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