scholarly journals Blood groups and secretory state in COVID-19

2021 ◽  
Vol 9 (4) ◽  
pp. 589-596
Author(s):  
Inessa A. Borodina ◽  
◽  
Inna A. Selezneva ◽  
Ol’ga V. Borisova ◽  
Ol’ga A. Baldina ◽  
...  
Keyword(s):  
Blood Group ◽  
Oral Fluid ◽  
Venous Blood ◽  
Modern Medicine ◽  
Group A ◽  
Coronavirus Infection ◽  
Antigen A ◽  
Personalized Approach ◽  
Microsoft Office ◽  
Relationship Of

INTRODUCTION: Despite the achievements of modern medicine, healthcare system is lacking in knowledge about the new coronavirus infection caused by the SARS-CoV-2 virus. AIM: To establish the relationship of the new coronavirus infection with the blood group according to the AB0 blood system in the Samara region and assess the secretory status of the oral fluid in patients with COVID-19. MATERIALS AND METHODS: This study was conducted from June 2019 to December 2020, and included 89 healthy individuals (38% males, 62% females, average age 24 ± 2.5 years) and 92 patients with COVID-19 (24% males and 76% females, average age 55.68 ± 1.83 years). The material for the study was oral fluid and venous blood. Determination of the blood group according to the AB0 system was carried out by a cross method, the secretory status of saliva according to the I. Vidas method. Descriptive methods were used for statistical data processing (arithmetic mean, error of the mean), calculation of the percentage of a whole number using computer programs IBM SPSS Statistics 23 and Microsoft Office Excel 2010. RESULTS: The distribution by blood group in patients with COVID-19 was as follows: A (II) blood group was found in 43.5%, O (I) in 36.9%, B (III) in 17.4%, AB (IV) in 2.2%. Rh-positive status was determined for 92.4%. Among secretory representatives, antigen A was secreted in 92.1%, and antigen B was secreted in 7.9% of cases. Antigens A and B were absent in the oral fluid of patients with AB (IV) blood group. CONCLUSIONS: This study confirmed the prevalence of A(II) blood group carriers among patients with COVID-19. In this case, the secretion of antigen A into the oral fluid is 92.1%. Group A antigen, being a glycoprotein, can act as a factor facilitating the mechanism of penetration of the SARS-CoV-2 into the human body. The results of the study indicate the need for a personalized approach at the stage of diagnosis and monitoring of the treatment of new coronavirus infection, as well as taking into consideration the blood group to develop preventive measures for COVID-19.

BLOOD GROUP AS A PREDICTOR OF GLYCEMIA AND LACTATEMIA IN CRITICAL CONDITION PATIENTS

2019 ◽  
Vol 64 (4) ◽  
pp. 216-220
Author(s):  
V. I. Kuzmicheva ◽  
F. N. Gylmiyarova ◽  
N. A. Koloteva ◽  
Yu. L. Ketsko ◽  
O. A. Gusyakova ◽  
...  
Keyword(s):  
Blood Group ◽  
Middle Age ◽  
Venous Blood ◽  
Statistical Processing ◽  
Critical Conditions ◽  
Glucose Content ◽  
Condition Evaluation ◽  
Threatening Condition ◽  
Life Threatening ◽  
Personalized Approach

Hyperlactatemia is a dangerous metabolic shift, manifested in an increase in the blood lactate content above 2.2 mmol / l. Changes in the content of lactate affect the function of vital organs and systems, disrupting the course of biochemical processes. This condition accompanies a large number of clinical situations, also it is a major factor, worsening the clinical outcome and the patient’s condition. The study of the characteristics of its occurrence and metabolic relationships helps to fulfill the diagnostic criteria for assessing the likelihood of an adverse outcome. The purpose of this study is to assess the variability of the content of lactate and glucose, as well as the glucose/lactate ratio, depending on the group of blood in the ABO system and the nosology of patients. 250 patients with various diseases whose condition required intensive care were examined, the middle age was 61.08 ± 13.6 years, and 446 practically healthy individuals who did not have acute somatic and infectious diseases, the middle age was 26.83 ± 1.46 years . We investigated the content of lactate and glucose, the glucose/lactate ratio, determined the belonging of the blood to ABO system. Statistical processing of the results was performed in the IBM SPSS Statistica 23.0. The data obtained indicate that patients with B (III) blood group have the highest lactate content in venous blood compared to the general population, and patients with AB (IV) blood group have the highest blood glucose level. In the group of patients with the highest median lactate content, the lowest glucose content was observed. The data presented demonstrate the importance of measuring and monitoring glucose, lactate, and their ratio in the management of patients in a life-threatening condition. Evaluation of metabolic variability depending on the different blood grouping of the ABO system in critical conditions involving hyperlactataemia can serve as an important tool in modeling a personalized approach to the patient.

scholarly journals THE IMMUNOLOGICAL RELATIONSHIP OF THE CAPSULAR POLYSACCHARIDE OF TYPE XIV PNEUMOCOCCUS TO THE BLOOD GROUP A SPECIFIC SUBSTANCE

1939 ◽  
Vol 70 (3) ◽  
pp. 239-247 ◽  
Author(s):  
Paul B. Beeson ◽  
Walther F. Goebel
Keyword(s):  
Blood Group ◽  
Capsular Polysaccharide ◽  
Horse Serum ◽  
Human Erythrocytes ◽  
Blood Group A ◽  
Marked Diminution ◽  
Specific Substance ◽  
Group A ◽  
Immunological Relationship ◽  
Relationship Of

1. The agglutination of human erythrocytes and the precipitation of the blood group A substance by Type XIV antipneumococcus horse serum are properties of the specific anticarbohydrate immune bodies in the serum. 2. Absorption of Type XIV antipneumococcus horse serum with the homologous bacterial polysaccharide removes the agglutinins for human erythrocytes as well as the precipitins for the group A substance. 3. Absorption of Type XIV antipneumococcus horse serum with the group A substance markedly diminishes the ability of the serum to agglutinate erythrocytes of all groups. 4. Absorption of Type XIV antipneumococcus horse serum with human erythrocytes causes a marked diminution in the precipitation with group A substance. 5. The chemical and immunological relationship between the specific substances of blood group A and the Type XIV Pneumococcus is discussed.

scholarly journals An Inheritable B-like Character in Persons of Blood Group A

Blood ◽  
1960 ◽  
Vol 16 (2) ◽  
pp. 1163-1172 ◽  
Author(s):  
JØRGEN ANDERSEN
Keyword(s):  
Blood Sample ◽  
Blood Group ◽  
Blood Cells ◽  
Group Character ◽  
Blood Samples ◽  
Blood Group A ◽  
The Family ◽  
Group A ◽  
Antigen A

Abstract In a previous paper the author reported investigations of a blood sample (Co) whose blood cells contained, in addition to a normal A antigen, a weak, atypical B-like antigen. The present paper deals with two blood samples, El and Do, which probably possessed the same weak, atypical B-like character. A study of El’s family showed that this blood group character, provisionally designated as Ab, may be inheritable, as it was found in two children and one grandchild of El’s. The serologic studies of the 5 Ab samples are reported, and on the basis of the family material the possible origin of the Ab character is discussed.

A Test of Satiation as a Function of Adaptation in Stuttering

1969 ◽  
Vol 12 (1) ◽  
pp. 110-117 ◽  
Author(s):  
Harold A. Peterson ◽  
Mary Beth Rieck ◽  
Rita K. Hoff
Keyword(s):  
Semantic Differential ◽  
Repeated Readings ◽  
Group A ◽  
Relationship Of ◽  
The Relationship

To test the relationship of adaptation and satiation as hypothesized by Jakobovits, satiation of meaning as a function of repeated readings for adaptation was measured in the performance of 14 male stutterers. The subjects as a group exhibited both satiation and adaptation, but the two phenomena did not occur simultaneously in a significant number of the members of the group. A reduction in meaningfulness, as measured by the semantic differential, was not shown to be a significant factor in the reduction of stuttering frequency for the individuals in the group. Satiation and adaptation were not established as the same phenomenon, although the two may still be related through another factor.

SISTEM PAKAR MENU MAKANAN SEHAT BAGI PENDERITA KOLESTEROL DENGAN METODE FORWARD CHAINING

2017 ◽  
Vol 3 (2) ◽  
pp. 72
Author(s):  
Gusnita Darmawati
Keyword(s):  
Expert System ◽  
Cholesterol Level ◽  
Blood Group ◽  
Healthy Food ◽  
Healthy Diet ◽  
Blood Type ◽  
Forward Chaining ◽  
Cholesterol Levels ◽  
Microsoft Office ◽  
Visual Basic 6.0

<p>Penelitian ini membangun suatu sistem pakar untuk menentukan menu makanan sehat berdasarkan golongan darah dan tingkat kadar kolesterol pasien dengan metode Forward Chaining. Tujuan untuk membantu orang awam dalam menentukan menu makanan sehat untuk pasien kolesterol. Sistem ini menganalisa masalah penentuan menu makanan sehat berdasarkan golongan darah dan tingkat kadar kolesterol pasien. Hasil yang diperoleh dari sitem pakar ini adalah berupa informasi makanan sehat yang akan dikonsumsi oleh pasien kolesterol dengan jenis golongan darah dan tingkat kadar kolesterol yang berbeda. Analisa dilakukan dengan cara mengetahui jenis golongan darah dan tingkat kadar kolesterol pasien yang ditampilkan oleh program sistem pakar ini, rancangan sistem ini menggunakan inference forward chaining, dengan implementasi sistem menggunakan sistem database Microsoft Office Access dan bahasa pemrograman Visual Basic 6.0. Dari rancangan aplikasi sistem pakar yang dibuat, maka orang awam yang memderita kolesterol dapat menentukan menu makanan sehat untuk di konsumsi berdasarkan golongan darah dan tingkat kadar kolesterol dengan menjalankan aplikasi sistem pakar.</p><p><em><br /></em></p><p><em><em>This study builds an expert system to determine the healthy food menu based on blood type and cholesterol levels of patients with Forward Chaining method. The goal is to help the layman in determining a healthy diet for cholesterol patients. This system analyzes the problem of determining healthy food menu based on blood group and patient cholesterol level. The results obtained from this expert system is in the form of healthy food information that will be consumed by cholesterol patients with the type of blood group and different cholesterol levels. From the design of expert system applications created, the layman who memderita cholesterol can determine the healthy diet to be consumed by blood type and cholesterol level by running an expert system application.<br /> <br /> </em></em></p>

A Weak Example of the Blood Group Antigen A

Vox Sanguinis ◽  
1961 ◽  
Vol 6 (2) ◽  
pp. 151-156 ◽  
Author(s):  
B. P. L. Moore ◽  
P. H. Newstead ◽  
Joanne Johnson
Keyword(s):  
Blood Group ◽  
Blood Group Antigen ◽  
Antigen A

scholarly journals Elevated alanine aminotransferase and low aspartate aminotransferase/alanine aminotransferase ratio are associated with chronic kidney disease among middle-aged women: a cross-sectional study

2020 ◽  
Vol 21 (1) ◽  
Author(s):  
Hirotaka Ochiai ◽  
Takako Shirasawa ◽  
Takahiko Yoshimoto ◽  
Satsue Nagahama ◽  
Akihiro Watanabe ◽  
...  
Keyword(s):  
Chronic Kidney Disease ◽  
Kidney Disease ◽  
Aspartate Aminotransferase ◽  
Alanine Aminotransferase ◽  
Venous Blood ◽  
Cross Sectional Study ◽  
Middle Aged ◽  
Cross Sectional ◽  
Alcoholic Fatty Liver ◽  
Relationship Of

Abstract Background Alanine aminotransferase (ALT) and aspartate aminotransferase (AST) to ALT ratio (AST/ALT ratio) have been shown to be related to non-alcoholic fatty liver disease or insulin resistance, which was associated with chronic kidney disease (CKD). However, it is unclear whether ALT and AST/ALT ratio are associated with CKD. In this study, we examined the relationship of ALT and AST/ALT ratio to CKD among middle-aged females in Japan. Methods The present study included 29,133 women aged 40 to 64 years who had an annual health checkup in Japan during April 2013 to March 2014. Venous blood samples were collected to measure ALT, AST, gamma-glutamyltransferase (GGT), and creatinine levels. In accordance with previous studies, ALT > 40 U/L and GGT > 50 U/L were determined as elevated, AST/ALT ratio < 1 was regarded as low, and CKD was defined as estimated glomerular filtration rate < 60 mL/min/1.73 m2 and/or proteinuria. Logistic regression model was used to calculate the odds ratio (OR) and 95% confidence interval (CI) for CKD. Results “Elevated ALT and elevated GGT” and “elevated ALT and non-elevated GGT” significantly increased the OR for CKD when compared with “non-elevated ALT and non-elevated GGT” (OR: 2.56, 95% CI: 2.10–3.12 and OR: 2.24, 95% CI: 1.81–2.77). Compared with “AST/ALT ratio ≥ 1 and non-elevated GGT”, “AST/ALT ratio < 1 and elevated GGT” and “AST/ALT ratio < 1 and non-elevated GGT” significantly increased the OR for CKD (OR: 2.73, 95% CI: 2.36–3.15 and OR: 1.68, 95% CI: 1.52–1.87). These findings still remained after adjustment for confounders. Conclusions Elevated ALT was associated with CKD regardless of GGT elevation. Moreover, low AST/ALT ratio was also associated with CKD independent of GGT elevation.

Sign in / Sign up

Export Citation Format

Share Document