scholarly journals Spirometric Indices in Type 2 Diabetes Mellitus Patients in a Nigerian Tertiary Institution

2021 ◽  
Vol 3 (3) ◽  
pp. 10-14
Author(s):  
Adekunle O. Adeoti ◽  
Taiwo H. Raimi ◽  
Joseph O. Fadare ◽  
Raphael Ibidapo
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Communicable Disease ◽  
Cross Sectional Study ◽  
Diabetic Patients ◽  
Tertiary Institution ◽  
Cross Sectional ◽  
Significant Difference

Background: Diabetes mellitus is a non-communicable disease of global health importance. It is a metabolic disorder caused by increased levels of blood glucose over a prolonged period of time. Type 2 diabetes mellitus (T2DM) is usually associated with obesity and insulin resistance. Several studies have also revealed that diabetes mellitus hampers pulmonary functions. This study was aimed at estimating the spirometric indices in type 2 diabetes mellitus patients. Methods: A cross-sectional study of T2DM patients and apparently healthy control attending the medical outpatient clinic in a tertiary institution in south western Nigeria. Results: A total of 146 participants with 73 patients with T2DM and 73 control groups. There were no significant differences in the age, body mass index, and gender distribution of the diabetics and control. However, patients with diabetes had higher SBP (133.2±20.17 mmHg vs 111.6±6.5 mmHg p<0.0001), and DBP (78.4±11.8mmHg vs 73.7±6.3 mmHg, p=0.003) when compared to the control. The mean FEV (1.98±0.5 vs 2.09±1.2, p=0.033), FVC (2.35±0.6 vs 2.53±1.3, p=0.045) and FEV/FVC ratio (83.61±7.2 vs 81.14±10.7, p=0.029) were significantly lower in diabetic patients when compared to matched controls. There was no significant difference in the PEF and FEF of both groups. Conclusion: Type 2 diabetes mellitus patients had significant decrease in their spirometric indices, hence pulmonary function should be included in the periodic comprehensive diabetic check for holistic management.

scholarly journals Prevalence of Metabolic Syndrome in individuals with Type 2 Diabetes Mellitus

2017 ◽  
Vol 70 (2) ◽  
pp. 265-270 ◽  
Author(s):  
José Cláudio Garcia Lira Neto ◽  
Mayra de Almeida Xavier ◽  
José Wicto Pereira Borges ◽  
Márcio Flávio Moura de Araújo ◽  
Marta Maria Coelho Damasceno ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Metabolic Syndrome ◽  
Type 2 Diabetes Mellitus ◽  
Descriptive Analysis ◽  
Cross Sectional Study ◽  
Diabetic Patients ◽  
Chi Square ◽  
Cross Sectional

ABSTRACT Objective: to identify the prevalence of Metabolic Syndrome and its components in a population of patients with type 2 Diabetes Mellitus. Method: a cross-sectional study was conducted with 201 diabetic patients. A descriptive analysis and Chi-square and Fisher's exact tests ( p <0.05) were performed. Results: the majority of participants were females and overweight, with a mean age of 63.1 years and a low level of education, and categorized as physically inactive. Of all individuals investigated, 50.7% were diagnosed with Metabolic Syndrome and 92% had at least one of the syndrome components with values beyond those recommended. Conclusion: it is essential to take preventive actions and develop studies that help to identify the factors associated with this syndrome.

scholarly journals DISTRIBUTION PATTERNS AND RISK FACTORS OF DYSLIPIDEMIA IN PATIENTS WITH TYPE 2 DIABETES MELLITUS: A CROSS-SECTIONAL STUDY IN BOGOR, INDONESIA

2020 ◽  
pp. 5-8
Author(s):  
SARASWATI PRADIPTA ◽  
HERI WIBOWO ◽  
DANTE SAKSONO HARBUWONO ◽  
EKOWATI RAHAJENG ◽  
RAHMA AYU LARASATI ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Risk Factors ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Density Lipoprotein ◽  
Cross Sectional Study ◽  
Diabetic Patients ◽  
Sectional Study ◽  
Cross Sectional

Objective: Type 2 diabetes mellitus (T2DM) patients tend to have abnormal lipid profiles, explaining the association between elevated cholesterol andtriglyceride levels in diabetic patients and coronary heart disease. This study aims to evaluate how the common risk factors for dyslipidemia affectthe lipid profile of diabetic patients and to determine which factors can be used as predictors for the occurrence of dyslipidemia in T2DM patients.Methods: A total of 238 diabetic patients (63 male and 175 female; age: 31–70 years) were enrolled in this cross-sectional study. All of them hadundergone regular examinations in cohort studies on risk factors for non-communicable diseases conducted by the Ministry of Health in Bogorbetween December 2017 and January 2018.Results: The result found that age differences did not affect lipid profile levels, and the females had higher mean values of body mass index (p<0.001),total cholesterol (TC) (p<0.05), and high-density lipoprotein (HDL) (p<0.001) than the males. The most common occurrences of dyslipidemia werehigh TC level (57.1%), followed by high low-density lipoprotein (LDL) level (47.1%), high triglyceride level (37.4%), and low HDL level (16.4%). Beingoverweight was found to be the best predictor of dyslipidemia.Conclusion: The results of this study suggest that in T2DM patients, sex affects TC and HDL levels, whereas age does not exert a significant effect onthe lipid profiles. In addition, poor glycemic control, hypertension, and obesity may serve as predictors of dyslipidemia in T2DM patients.

scholarly journals A STUDY OF LIPID PROFILE IN DIABETES MELLITUS TYPE-2 PATIENTS

2021 ◽  
Vol 5 (11) ◽  
Author(s):  
Vipin Kumar ◽  
Maya Pensiya ◽  
V B Singh
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Lipid Profile ◽  
Diabetic Patients ◽  
Cross Sectional ◽  
Significant Difference ◽  
Sugar Levels ◽  
And Control

Background: To study the lipid profile in diabetes mellitus in type 2 Diabetes mellitus patients. Methods: This is a cross sectional case control study. 100 patients of type 2 diabetes mellitus and 100 age and sex matched healthy controls were taken. Lipid profile were done in cases and controls using appropriate tests. Results: The fasting blood sugar levels in all the diabetics were significantly higher as compare to control. There was significant difference in mean HDL, Triglycerides level in diabetic and control patients. There was no significant difference in LDL, Cholesterol level in Diabetic and control patients. Conclusion: We concluded that there is a high prevalence of elevated lipid levels among the diabetic patients. Keywords: Diabetes Mellitus -2, Cholesterol, Lipid Profile

Microalbuminuria and its associations with clinical profile and complications of type 2 Diabetes Mellitus

2021 ◽  
Vol 10 (1) ◽  
pp. 29-32
Author(s):  
Sanjay Shrestha ◽  
Rajesh Kumar Mandal ◽  
Kijan Maharjan
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Cross Sectional Study ◽  
Clinical Profile ◽  
Diabetic Patients ◽  
Cross Sectional ◽  
Spot Urine ◽  
Management Of Complications

Background and Aims: Microalbuminuria is an early marker of diabetic nephropathy, which accounts for a significant reduction in life expectancy of diabetic patients. Timely detection of microalbuminuria facilitates appropriate preventive and therapeutic approaches to minimize risks. The aim of this study is to determine the prevalence and association of microalbuminuria with clinical profile and complications of type 2 diabetes mellitus. Methods: This study was a descriptive, cross sectional study involving 100 diabetic subjects between July 2018 to January 2019 at Bir Hospital. Microalbuminuria (mg/dl) was defined as spot urine albumin to creatinine ratio of 30-300 mg/g (Kidney Disease Improving Global Outcomes guidelines) in a single spot urine sample. Statistical analysis was done using Statistical package for the social sciences version 20. Results: Microalbuminuria was found in 35% of the sample and the rate was significantly higher among males (P =0.027). Microalbuminuria was significantly related to Body mass index (P = 0.018), duration of diabetes (P =0.000), retinopathy (P = 0.000) and stroke (P = 0.043). No statistically significant relation was found between microalbuminuria and age (P = 0.366), hypertension (P = 0.208), HbA1c (P = 0.098), dyslipidemia (P = 0.171) and ischemic heart disease (P = 0.651). Conclusions: This study shows high prevalence of microalbuminuria in Nepalese Type 2 diabetes mellitus. Screening for microalbuminuria should be done for all the type 2 diabetes mellitus patients for early detection and management of complications of diabetes mellitus.  

scholarly journals Study of effect of glycemic control on haemoglobin levels in patients with type 2 diabetes mellitus

2020 ◽  
Vol 7 (3) ◽  
pp. 497
Author(s):  
Aishhwarrya Umeshchandara G. ◽  
Ravi K.
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Glycemic Control ◽  
Age Distribution ◽  
Organ Damage ◽  
Cross Sectional Study ◽  
Diabetic Patients ◽  
Cross Sectional

Background: Anemia is more frequent and severe in diabetics compared to non-diabetic patients. Chronic anemia results in tissue hypoxia, which is known to play a key role in diabetes-associated organ damage. Hence it is important to diagnose and correct anemia in diabetic patients. This study was done to elucidate the effect of glycemic control on haemoglobin levels in patients with type 2 Diabetes mellitus.Methods: The present study is an observational, cross sectional study conducted between November 2017 to May 2019 carried out in hospitals attached to Bangalore Medical college and Research Institute. A sample of 60 patients with Diabetes mellitus were included, out of which 28 were female and 32 were male patients.Results: Study was conducted on 60 patients, the age distribution was between 29yrs to 88yrs with mean age was 56±11yrs. Out of 60 patients 23 patients had anemia. There was slight positive correlation between haemoglobin percentage and HbA1c. But this was not statistically significant.Conclusions: The study concludes that Glycemic control was not found to influence the Haemoglobin levels in patients with Type 2 diabetes mellitus in a significant manner. In subjects with anemia, multiple other issues need to be addressed for improvement in haematocrit value and prevention of complications of diabetes apart from glycemic control.

scholarly journals Coagulation Impairment in Type 2 Diabetes Mellitus

2015 ◽  
Vol 10 (1) ◽  
pp. 26-29 ◽  
Author(s):  
Fayeza Karim ◽  
Qazi Shamima Akter ◽  
Shamima Jahan ◽  
Afruza Khanom ◽  
Samira Haque ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Prothrombin Time ◽  
Partial Thromboplastin Time ◽  
Cross Sectional Study ◽  
Activated Partial Thromboplastin Time ◽  
Diabetic Patients ◽  
Cross Sectional

Background: Complication of diabetes mellitus (DM) includes coagulation impairment. Hypercoagulable state in patient with DM may accelerate thromboembolic risk for cardiovascular disease (CVD).Objective: To assess Prothrombin Time and Activated Partial Thromboplastin Time in type 2 diabetes mellitus for observing their coagubility status.Methods: This cross sectional study was conducted in the Department of Physiology, Dhaka Medical College, Dhaka from July 2013 to June 2014. One hundred male patients with type 2 diabetes mellitus aged 40-60 years and one hundred age, BMI matched healthy subjects were included as control in this study. Patients were selected from BIRDEM, Dhaka. Prothrombin Time (PT), Activated Partial Thromboplastin Time (APTT) were estimated by auto analyzer. For statistical analysis unpaired student’t test was used.Results: In this study PT and APTT were significantly (P<0.001) lower in diabetes mellitus than those of control group.Conclusion: From this study, it may be concluded that diabetic patients are prone to develop coagulation impairment.Bangladesh Soc Physiol. 2015, June; 10(1): 26-29

scholarly journals Gender Variation of Lipid Profiles of Type-2 Diabetes Mellitus Patients attended at a Specialized Diabetic Hospital in Dhaka

2015 ◽  
Vol 2 (2) ◽  
pp. 34-38 ◽  
Author(s):  
Roksana Yeasmin ◽  
Nazmun Nahar ◽  
MA Muttalib ◽  
Md. Nizamul Hoque Bhuiyan ◽  
ATM Zoadur Rahim Zahid ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Blood Sugar ◽  
Diabetic Patients ◽  
Cross Sectional ◽  
Physiological Level ◽  
Significant Difference ◽  
The Difference

Background: The pattern of dyslipidemia varies among the patients of type 2 of diabetes mellitus. Objective: The purpose of the present study was to observe gender difference of lipid abnormalities in type-2 Diabetes Mellitus patients.Methodology: This cross sectional comparative study was conducted in the OPD of Department of medicine at BIRDEM, Dhaka from January, 2014 to July, 2014 for a period of six months. Convenient purposive sampling method was used and data assessed in a prospective manner. Blood sugar (FBS, ABF), lipid profile (TG, TC, LDLC, and HDLC) were measured. Statistical analyses were performed with the SPSS software program.Results: A total number of 400 type 2 DM patients (200 males and 200 females) attending to BIRDEM OPD were recruited in this study. Blood sugar was higher than normal in both male and female (FBS=8.79±.20, 8.64±0.22 respectively and ABF=12.15±0.27, 11.8±0.29 mmol/l respectively). TG level was also higher in two groups of study subjects with male level is slightly more than female (194.99±6.72 and 185.21±15.51 respectively) with no significant difference between the groups (P>.05). Total cholesterol and LDL-C level was within normal physiological level in both groups, where as these levels were higher in female in comparison to male (TC=184.44±3.33 &166.16±3.04 respectively, LDLC=109.68±2.59 & 88.66±2.59 respectively), showing significant difference between the groups (P=.000). HDL-C was below normal in both male (38.28± 48) and female (39.02±2.59); however HDL-C was slightly higher in female than male and the difference was insignificant (p=.330). Conclusion: In conclusion dyslipidemia were observed in a greater proportion of female diabetic patients than male diabetic patients.Journal of Current and Advance Medical Research, 2015;2(2):34-38

scholarly journals PERBANDINGAN JUMLAH TROMBOSIT PADA PASIEN DIABETES MELITUS TIPE 2 YANG MENGGUNAKAN ASPIRIN DAN TIDAK MENGGUNAKAN ASPIRIN

2013 ◽  
Vol 1 (1) ◽  
Author(s):  
Dwi P. Palimbunga ◽  
Karel Pandelaki ◽  
Arthur E. Mongan ◽  
Firginia Manoppo
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Platelet Count ◽  
Cross Sectional Study ◽  
Cross Sectional ◽  
Fourfold Increase ◽  
Significant Difference ◽  
Diabetes Melitus

Abstract: Patients with type-2 diabetes mellitus are characterized by an acceleration thrombopoiesis, an increased platelet turnover and a decreased platelet survival time which affect platelet count, that cause the increasing of proportion of large and reactive platelets, and hence more thrombogenic. People with diabetes have a two- to fourfold increase in the risk of dying from the complications of cardiovascular disease. Aspirin therapy is recommended for the primary and secondary prevention of cardiovascular events in most people with diabetes. This study was an descriptive analytic method with cross sectional study design. The subjects in this study involve 112 people, 56 people treated with aspirin, and the 56 others were not who signed in endocrine metabolic department of RSUP Prof. Dr. R. D Kandou Manado. Data were taken from medical record. The Mann-Whitney test showed that there was no significant difference between the platelet count in patients with type-2 diabetes mellitus treated with aspirin and patients who were not. Conclusion: There was no significant difference between the platelet count in patients with type-2 diabetes mellitustreated with aspirin and patients who were not. Key word:Aspirin, Type-2 Diabetes Mellitus, Platelet Count  Abstrak: Pada pasien diabetes melitus tipe-2 terjadi percepatan trombopoiesis, peningkatan pergantian trombosit dan penurunan waktu hidup trombosit yang mempengaruhi jumlah trombosit, yang menyebabkan terjadinya peningkatan ukuran trombosit yang lebih besar dan reaktif, sehingga bersifat trombogenik. Risiko kematian karena komplikasi penyakit jantung meningkat dua sampai empat kali lipat. Aspirin digunakan sebagai pencegahan primer dan sekunder terhadap kejadian kardiovaskular pada pasien diabetes. Tujuan penelitian ini untuk melihat perbedaan jumlah trombosit pada pasien diabetes melitus tipe-2 yang menggunakan aspirin dan tidak menggunakan aspirin. Penelitian ini bersifat deskriptif analitik dengan rancang penelitian cross sectional. Subjek dalam penelitian ini berjumlah 112 orang, 56 orang yang menggunakan aspirin dan 56 orang lainnya tidak menggunakan aspirin yang terdaftar di Poliklinik Endokrin Metabolik RSUP Prof. Dr. R. D. Kandou Manado. Data diambil dari catatan rekam medik. Hasil penelitian menggunakan uji Mann-Whitney,menunjukkan bahwa tidak terdapat perbedaan yang signifikan antara jumlah trombosit pada pasien diabetes melitus tipe-2 yang menggunakan aspirin dan tidak menggunakan aspirin (p=0,059). Simpulan: Tidak terdapat perbedaan signifikan antara jumlah trombosit pada pasien diabetes melitus tipe 2 yang menggunakan aspirin dan tidak menggunakan aspirin. Kata Kunci: Aspirin, Diabetes Melitus Tipe-2, Jumlah Trombosit

scholarly journals Incidence of refractive errors in diabetic patients

2020 ◽  
Vol 11 (4) ◽  
pp. 7271-7274
Author(s):  
Krithik Jain N ◽  
XavierJayseelan C
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Cross Sectional Study ◽  
Diabetic Patients ◽  
Refractive Errors ◽  
Sectional Study ◽  
Cross Sectional ◽  
Common Error

The aim of the study is to find the incidence of refractive errors in diabetic individuals. Diabetes mellitus is highly prevalent in the current world in both developing and developed countries due to the lifestyle modifications. Refractive errors of eye are a very common group of disorder associated with diabetic people leading to the impairment of vision. Hence the study of incidence of refractive errors in patients with type 2 Diabetes mellitus was conducted. It was a cross-sectional study conducted at a tertiary health care centre and following was the methodology. One hundred eyes of fifty individuals were taken into consideration from Jan 2020 to March 2020, who were affected with type 2 Diabetes mellitus. These fifty individuals underwent subjective refraction of both the eyes. The results obtained were only 17 eyes (17%) being emmetropic, remaining 83 eyes (83%) were found to be ametropic. In the 83 ametropic eyes 22 eyes (22%) were myopic, 39 eyes (39%) were hypermetropic and 22 eyes (22%) had astigmatism. In the current Cross-sectional study refractive errors were noted in 83% of individual and hypermetropia being the most common error with a prevalence of 39%.

scholarly journals Medication adherence in type 2 diabetes mellitus patients during Covid-19 pandemic: a cross-sectional study from the United Arab Emirates

F1000Research ◽  
2021 ◽  
Vol 10 ◽  
pp. 435
Author(s):  
Ameena Asheq ◽  
Akram Ashames ◽  
Moawia Al-Tabakha ◽  
Nageeb Hassan ◽  
Ammar Jairoun
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Medication Adherence ◽  
United Arab Emirates ◽  
Cross Sectional Study ◽  
Diabetic Patients ◽  
Sectional Study ◽  
Cross Sectional

Background: Patients with chronic diseases often experience difficulty adhering to recommended treatments as instructed by their healthcare professionals. Recently, diabetes has been associated with the severity of the novel coronavirus disease (Covid-19), which raises the importance of improving medication adherence for diabetic patients to enhance the right use of antidiabetics amid the Covid-19 pandemic. Methods: This work assesses medication adherence among type 2 diabetes mellitus patients in the United Arab Emirates (UAE) and identifies the set of key demographic and health factors significantly associated with medication adherence. A descriptive cross-sectional study was conducted on an appropriate sample of type 2 diabetic patients in the UAE, with 180 patients of both genders and various social levels. A validated version of the eight-item Morisky Medication Adherence Scale (MMAS) was used for data collection. Results:  The average MMAS score was 4.88, with 95% confidence intervals (CI) 4.6 and 5.2. 61.67% (n=111), 28.89% (n=52), and 9.44% (n=17) of patients were categorized into low, medium, and high adherent groups, respectively. These findings indicate that a high level of non-compliance to antidiabetic regimens among the population in the UAE. Conclusions: Patients demonstrated low level of compliance to antidiabetic regimens. Therefore, they must receive up-to-date knowledge about the disease and the treatment and enable easy access to their health care providers to enhance medication adherence.

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