scholarly journals CORRECTION OF MENSTRUAL FUNCTION DISORDERS IN GIRLS WITH OBESITY

2021 ◽  
Vol 20 (1) ◽  
pp. 5-10
Author(s):  
Alla Borshulyak ◽  
Oksana Andriyets ◽  
Svitlana Pryimak ◽  
Anatoliy Andriyets
Keyword(s):  
Diagnostic Algorithm ◽  
Diet Therapy ◽  
The Body ◽  
Cycle Duration ◽  
Menstrual Disorders ◽  
Menstrual Dysfunction ◽  
Menstrual Function ◽  
Normal Limits ◽  
Treatment Measures ◽  
Therapeutic Measures

Based on the literature datа and the results of our studies, menstrual dysfunction in teen girls leads to disorders of the reproductive system in fertile age. Establishment of normal menstrual function in teen girls is an eff ective measure for the prevention of future reproductive health disorders, which leads to improved methods of menstrual disorders diagnostics in overweight girls by analyzing clinical and anamnestic data, biochemical markers, development of diagnostic algorithm and pathogenetically based correction of menstrual disorders. To gain this aim, it was proposed to include to the complex of conventional therapy, diet therapy and drugs myo-inositol (inofolic softgel) and metformin. Evaluation of the treatment eff ectiveness was performed on the regression dynamics of the disease main clinical symptom and the normalization of hormonal status indicators. The result of treatment was considered satisfactory when the patient had regular menstruation for 12 months on the background of the therapy, and the maintenance of irregular menstruation with a cycle duration of more than 38 days was unsatisfactory. As a result of treatment the body mass index has decreased in all the patients which received our complex of therapeutic measures, especially for obesity of the second and third degree what proves the eff ectiveness of complex treatment. The appointment of proposed complex of treatment measures for patients is pathogenetically based, because after treatment, previously detected insulin resistance decreased signifi cantly in all groups, but most and reliably in groups with obesity of the second and third degree and became almost within normal limits.

Physiological and Hereditary Hyperbilirubinemia in Athletes: Role in Reducing Efficiency and Correction Methodology

2020 ◽  
Vol 5 (5) ◽  
pp. 386-393
Author(s):  
L. M. Gunina ◽  
◽  
Kazys Mylashyus ◽  
Voitenko V. L. ◽  
◽  
...  
Keyword(s):  
Physical Activity ◽  
Functional State ◽  
Oxygen Demand ◽  
Diagnostic Algorithm ◽  
Drug Prevention ◽  
The Body ◽  
Erythrocyte Membranes ◽  
Pharmacological Agents ◽  
Bilirubin Metabolism ◽  
The Individual

Under high-intensity loads, the athlete's bodies take place a number of biochemical reactions and physiological processes that can lead to hyperbilirubinemia. The factors that can initiate the onset of this phenomenon include the syndrome of micro-damage muscle, violation of the integrity of erythrocyte membranes, decreased blood pH, malnutrition and increase oxygen demand of the body. Degree of expression of manifestations of physiological bilirubinemia depends on the level of adaptation of the athlete to the physical activities offered. Hyperbilirubinemia in athletes can be one of the components of the deterioration of the functional state, forming the symptoms of endogenous intoxication. The relevance of this problem in sport lies in the relatively low detection rate of hyperbilirubinemia due to the lack of regular screening studies. However, in drawing up a plan of nutritional- metabolic support for training and competitive activity and recovery measures, must not only the individual reaction of the athlete body to physical activity, but also the severity of shifts in the indicators of bilirubin metabolism and their ratio. The article describes the reasons for the increase in bilirubin levels, which can be caused by both the effect of physical activity and by the presence of pathological processes in athletes. The factors influencing the blood serum’s bilirubin content are also highlighted, which include the state of erythrocyte cell membranes and the rate of hemoglobin destruction, the functional state of the liver, the specifics of physical loads and the use of ergogenic pharmacological agents by athletes. Particular accent has been placed on the illumination of hereditary hyperbilirubinemias, which may have been detected at the stage of selection of athletes. The most common phenomenon is Gilbert's syndrome, which occurs in 2-5% of cases in the general population, is characterized in the clinic by a benign flow and is manifested by episodes of jaundice and an increase in total bilirubin content to moderate values due to indirect. The frequency of detection of hyperbilirubinemias in the population of athletes is 4.68%, among which Gilbert's disease accounts for almost half (48.7%). Conclusion. The work highlighted the pathogenesis and diagnostic algorithm of Gilbert's disease, and also emphasized that its drug prevention and correction in athletes to maintain functional and physical fitness should be carried out taking into account anti-doping rules, which requires upon diagnosis timely receipt of a therapeutic exclusion

Theoretical foundations and general provisions of autohemotherapy

1930 ◽  
Vol 26 (7) ◽  
pp. 118-124
Author(s):  
S. I. Sherman
Keyword(s):  
Morphological Changes ◽  
Scientific Basis ◽  
The Body ◽  
Practical Medicine ◽  
Routes Of Administration ◽  
Therapeutic Measures ◽  
Theoretical Foundations ◽  
Dosage Frequency

Currently, autohemotherapy takes one of the places of honor among; of our therapeutic measures and there is not a single area of ​​practical medicine where oisch is not applied. At the same time, this type of therapy still does not have an exact scientific basis; Thus, there are many different views on the essence of the action of this method, but there are still no precise indications and contraindications for the use of autohemotherapy for certain types of diseases, then the dosage, frequency of injections, their number, etc., vary sharply among different authors. we will review the following issues - the essence of the action of autohemotherapy, the dosage and frequency of injections, the reaction of the body (general, focal, local), the advantage of one or another method of using autoblood injections (intracutaneous, subcutaneous and intramuscular routes of administration) and, finally, morphological changes in blood during this method of treatment.

Organization of Therapeutic Nutrition in a Complex of Therapeutic Measures for Acute Glomerulonephritis

2020 ◽  
pp. 14-20
Author(s):  
Elena Vitalievna Perminova
Keyword(s):  
Salt Content ◽  
The Body ◽  
Acute Glomerulonephritis ◽  
Dietary Recommendations ◽  
Excretory Function ◽  
Special Diet ◽  
Organization Of Care ◽  
Negative Effect ◽  
Therapeutic Measures ◽  
High Incidence Rate

Organization of care for patients with glomerulonephritis is a rather urgent problem today, due to the high incidence rate and the tendency to progression of renal dysfunction. When discussing treatment issues, it is necessary to pay attention to the fulfillment of three basic requirements for patients, which include normalization of the life regime (in particular, the exclusion of night work, avoiding stressful situations and heavy physical activity when having high blood pressure), the implementation of certain dietary recommendations and prolonged drug treatment [3]. Diseases of the kidneys as the main organ, the affection of which leads to a deterioration of excretory function, require a special diet with a restriction of a number of products. Against the background of glomerulonephritis disruption of the process of glomerular filtration, which in some cases leads to the development of renal failure, it is necessary to reduce the intake of food substances that can have a negative effect on the body — alcohol, smoked meats, spicy, salty foods, preserves, sausages, foods with high protein and salt content. Moreover, one should also take control of the amount of fluid consumed and ensure compliance with the frequency and regularity of food intake.

scholarly journals Investigation on fish health and diseases in rural pond aquaculture in three districts of Bangladesh

2014 ◽  
Vol 11 (2) ◽  
pp. 377-384 ◽  
Author(s):  
MM Hasan ◽  
MAR Faruk ◽  
IZ Anka ◽  
MAK Azad
Keyword(s):  
Health Management ◽  
Group Discussion ◽  
Silver Carp ◽  
The Body ◽  
Catla Catla ◽  
Hypophthalmichthys Molitrix ◽  
Fish Health ◽  
Pond Aquaculture ◽  
Pangasianodon Hypophthalmus ◽  
Treatment Measures

The present study was conducted to know the culture strategies and fish health and disease problems in pond aquaculture in Mymensingh, Bogra and Pabna districts of Bangladesh. Questionnaire interview and participatory rural appraisal tools like focus group discussion (FGD) were conducted with selected fish farmers. In total 90 farmers were interviewed and 9 FGD sessions were conducted. Most of the respondents practiced carp and pangas polyculture and they had disease problems in their ponds. Prevalence of fish disease varied with cultured species and locations. The most prevalent diseases as reported by the farmers were pop eye (57.78%), ventral reddening (55.55%), tail and fin rot (48.89), hemorrhagic lesion over the body surface (45.56%), dropsy (40%), gill rot (40%), white spot (40%) and epizootic ulcerative syndrome or EUS (33.33%). According to farmers opinion most susceptible species to disease was silver carp, Hypophthalmichthys molitrix (57.78%); followed by mrigal, Cirrhinus cirrhosus (50%); catla, Catla catla (47.78%); sarputi, Barbodes gonionotus (47.78%); rui, Labio rohita (42.22%) and pangas, Pangasianodon hypophthalmus (42.22%). Higher mortality was found in pangas (53.56%). Clinically, pangas, koi and sarputi were found severely affected. Most of the farmers used some treatment measures against disease problems. This study also highlited some fish health management problems in pond aquaculture. Further studies should include identification and characterization of pathogens involved in different types of diseases in pond aquaculture. DOI: http://dx.doi.org/10.3329/jbau.v11i2.19944 J. Bangladesh Agril. Univ. 11(2): 377-384, 2013

scholarly journals A Case of Invasive Mole

2017 ◽  
Vol 12 (2) ◽  
pp. 86-87
Author(s):  
Shahana Ahmed ◽  
Dipti Rani Shaha
Keyword(s):  
Hydatidiform Mole ◽  
The Body ◽  
Emergency Laparotomy ◽  
Molar Pregnancy ◽  
Complete Hydatidiform Mole ◽  
Partial Hydatidiform Mole ◽  
Normal Limits ◽  
History Of ◽  
Invasive Mole

Invasive mole is a condition where a molar pregnancy, such as a partial hydatidiform mole or complete hydatidiform mole, invades the wall of the uterus, potentially spreading and metastasizing to other parts of the body. Here is a case who presented with history of evacuation for molar pregnancy. She presented with irregular P/V bleeding on and off and after admission silent perforation with massive haemoperitoneum was detected for which emergency laparotomy was done. She recovered and was followed up till her b-hCG levels were within normal limits. As patient presented to us with haemoperitoneum and on laparotomy, there was invasion into whole of the uterus, it could not be saved and hysterectomy was done.Faridpur Med. Coll. J. Jul 2017;12(2): 86-87

scholarly journals Relationships between dietary macronutrients and adult neurogenesis in the regulation of energy metabolism – CORRIGENDUM

2013 ◽  
Vol 111 (4) ◽  
pp. 755-755
Author(s):  
Marianne A. Yon ◽  
Suzanna L. Mauger ◽  
Lucy C. Pickavance
Keyword(s):  
Body Weight ◽  
Energy Metabolism ◽  
Adult Neurogenesis ◽  
Brain Regions ◽  
The Body ◽  
Adult Brain ◽  
Metabolic Dysfunction ◽  
Neurogenic Niche ◽  
Normal Limits ◽  
Simple Carbohydrates

Of the environmental factors which have an impact on body weight, nutrients are most influential. Within normal limits, hypothalamic and related neuronal populations correct perturbations in energy metabolism, to return the body to its nutritional set-point, either through direct response to nutrients or indirectly via peripheral appetite signals. Excessive intake of certain macronutrients, such as simple carbohydrates and SFA, can lead to obesity and attendant metabolic dysfunction, also reflected in alterations in structural plasticity, and, intriguingly, neurogenesis, in some of these brain regions. Neurogenesis, previously thought to occur only in the embryo, is now known to take place in the adult brain, dependent on numerous stimulating and inhibiting factors, including dietary components. Because of classic associations between neurogenesis and the hippocampus, in learning and cognition, this brain region has also been the focus of attention in the study of links between diet and neurogenesis. Recently, however, a more complete picture of this relationship has been building: not only has the hypothalamus been shown to satisfy the criteria for a neurogenic niche, but appetite-related mediators, including circulating hormones, such as leptin and ghrelin, pro-inflammatory cytokines and the endocannabinoid intracellular messengers, are also being examined for their potential role in mediating neurogenic responses to macronutrients. The present review draws together these observations and investigates whether n-3 PUFA may exert their attenuating effects on body weight through the stimulation of adult neurogenesis. Exploration of the effects of nutraceuticals on neurogenic brain regions may encourage the development of new rational therapies in the fight against obesity.

scholarly journals The Effects of Whole Body Vibration in Physiotherapy – a Review of the Literature

2019 ◽  
Vol 61 (3) ◽  
pp. 208-212
Author(s):  
Mateusz Bartczyk ◽  
Andrzej Suchanowski ◽  
Marta Woldańska-Okońska
Keyword(s):  
Sports Injuries ◽  
Cardiovascular Response ◽  
Whole Body Vibration ◽  
The Body ◽  
Whole Body ◽  
Incomplete Spinal Cord Injury ◽  
Body Vibration ◽  
Stimulation Parameters ◽  
Cord Injury ◽  
Therapeutic Measures

Over the last decade, the use of vibration-supported therapeutic measures has been increased. There are many devices in the market that generate whole body vibration, but they can be divided into three groups due to the frequency, amplitude and direction of the vibrations being applied to the body. The aim of the work is to analyze the results of the most important works discussing the use and effectiveness of the therapeutic effect of vibrations on the human body. The studies are indicative of favourable changes to the symptoms of neurodegenerative diseases, neurological dysfunctions, incomplete spinal cord injury, sarcopenia and senile age disorders, osteoporosis, sports injuries. The use of whole body vibration does not result in significant changes to the hemodynamic function during therapy, although appropriate stimulation parameters may induce sufficient cardiovascular response to improve overall physical fitness. In the physiotherapy procedure, the whole body vibration is another means of increasing the effect of the therapy used.

scholarly journals Iodometric Quantitative Analysis Method of Ascorbic Acid in Tablets

2019 ◽  
Vol 70 (10) ◽  
pp. 3555-3560
Author(s):  
Costinela Valerica Georgescu ◽  
Cristian Catalin Gavat ◽  
Doina Carina Voinescu
Keyword(s):  
Ascorbic Acid ◽  
Quantitative Analysis ◽  
Standard Deviation ◽  
Statistical Significance ◽  
The Body ◽  
Water Soluble ◽  
International Standards ◽  
Titration Method ◽  
Normal Limits ◽  
Relative Standard

Ascorbic acid is a water-soluble vitamin provided with strong antioxidant action, that fulfills an important immune protective role of the body against infections and prevents various cancers appearance. The main goal of this study was to exactly quantify pure ascorbic acid in tablets of two pharmaceuticals. Proposed objective consisted in improvement and application of a iodometric titration method in ascorbic acid quantitative analysis. Ascorbic acid content per tablet in both studied pharmaceuticals was 173.84 mg, very close to official stated amount of active substance (180 mg). Allowed percentage deviation from declared content of pure ascorbic acid was only 3.42 %, below maximum value of � 5 % imposed by Romanian Pharmacopoeia 10-th Edition, according to European and International standards. Statistical analysis confirmed experimental obtained results and revealed low Standard Error value SE = 0.214476, which has fallen within normal limits. Confidence Level value (95.0 %) = 0.551328 and Standard Deviation SD = 0.525357. were within normal range of values. Relative Standard Deviation (Coefficient of variation or homogeneity) RSD = 26.268% was found below maximum range of accepted values (30-35%). P value = 7.44. 10-6 was located within normal limits, P [ 0.001, so the experimental obtained results has shown highest statistical significance. Thus, studied titration method can be successfully used in quantitative analysis of ascorbic acid from different samples.

scholarly journals Hormonal regulation of menstrual function in patients of reproductive age with acromegaly

2019 ◽  
Vol 15 (4) ◽  
pp. 59-64 ◽  
Author(s):  
Svetlana Yu. Vorotnikova ◽  
Larisa K. Dzeranova ◽  
Irina V. Stanoevich ◽  
Ekaterina A. Pigarova ◽  
Elena N. Andreeva ◽  
...  
Keyword(s):  
Hormonal Regulation ◽  
Hypogonadotropic Hypogonadism ◽  
Mass Effect ◽  
Reproductive Age ◽  
Menstrual Disorders ◽  
Serum Samples ◽  
Menstrual Function ◽  
Healthy Women ◽  
Excessive Secretion ◽  
Preliminary Extraction

Background: The frequency of menstrual disorders in patients with acromegaly is 4084% and are caused by three main reasons the development of normal or hypogonadotropic hypogonadism due to hyperprolactinemia or a mass effect of the tumor and direct effects of GH and IGF-1 on the reproductive system. Nevertheless the exact mechanisms of reproductive dysfunction are not clear now. Hypothalamic structures play significant role in the regulation of hypothalamic-pituitary-ovary axis, so its important to study key neuropeptides and evaluate their effects to the pathogenesis of ovarian dysfunction during excessive secretion of growth hormone. Aim: The aim of the work is to study the hormonal regulation of menstrual function in patients of reproductive age with acromegaly in the active stage of the disease. Material and methods: The study included patients with a confirmed diagnosis of acromegaly and healthy women, comparable in age and BMI. Blood serum samples were taken in the morning (89 hours) on an empty stomach for 35 days of the menstrual cycle or on any day with amenorrhea and frozen at -70C. The hormonal study was carried out by an enzyme immunoassay, in the case of a kisspeptin, with the preliminary extraction of serum samples. Results: The study included 31 patients with acromegaly and 15 healthy women. Between groups there was a statistically significant decrease in levels of LH (p = 0.001), FSH (p = 0.09), inhibin B (p = 0.003), and kisspeptin (p = 0.00005). The frequency of hyperprolactinemia in the cohort of patients was 51.6%. During the correlation analysis, a negative dependence of kisspeptin on the levels of GH and IGF-1 was detected (r = -0.54, p = 0.002 and r = -0.63, p = 0.0002). Conclusions: The severity of the central depression of regulation of menstrual function in patients with acromegaly may be due to the degree of disease activity.

scholarly journals Kandidias Oral pada Penderita Anemia Defisiensi Besi (Fe) dan Penetalaksanaannya

2012 ◽  
Vol 19 (1) ◽  
pp. 77
Author(s):  
Sri Budiarti Wongsohardjono
Keyword(s):  
Body Weight ◽  
Iron Deficiency ◽  
Iron Deficiency Anemia ◽  
Oral Candidiasis ◽  
Dorsal Surface ◽  
Body Weight Loss ◽  
Microcytic Anemia ◽  
The Body ◽  
Deficiency Anemia ◽  
Normal Limits

Background: Iron deficiency anemia is a microcytic anemia caused by chronic blood loss dueto such problems as excessive menstrual flow, gastrointestinal bleeding, gasterektomi or malabsorption that reduces the absorption of Fe. Predisposing factors that lead to the disruption of the ecology of oral candidiasis or oral microbiological changes can be due to malnutrition (iron deficiency, folic acid, vitamin B12) and the very old age. Objective: To report a case of iron deficiency anemia with oral candidiasis and its management. Case Report: A 69-year man in the reference by peer demonstrated swollen gums, mouth pain and difficulty in swallowing. A moth ago he was hospitalized and boarded for a week but no change, his body weight loss was 25kg. paleconjunctiva and face, droliing, looked weak. The body temperature was 370 C; the BP measurement was: 125/80mmHg; with body weight was 50kg; right and left submandibular  lymph nodes become enlarging and soreness palpatiom. Symmetrical face. Right and left lip corners are angular kheilitis, cheek mucosa, palate hyperemia, gingival stipling was disappeared, hyperemia, dorsal surface smooth tongue, hyperemia, depapilasi, OHI: bad; thick saliva, hypersalivation. A lot of dental caries and the remaining roots. Management: Examination of the saliva with KOH solution looked a hyphe. Routine blood tests and profile of fe all within normal limits except RBC was 3,37.106 / uL; HGB: 11.0 g / dl; HCT: 32.2%, Fe 29.00 u g / dl (below normal). Treatment with 3% perhidrol mouthwash, Nyistatin solution 3 x daily. Zegase tablet 2x daily. Paracetamol tablets if necessary. Conclusion sixteen days later the patient recovered.

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