scholarly journals Blood type mystery

Author(s):  
Inga Tymofiychuk ◽  
Svetlana Semenenko

In ancient times there was blood a symbol of life flow and energy. It was believed that it gives strength. Red paint and wine were used in traditional rites.Blood type is able to tell a lot of interesting things about its "owner" facts. Having information about your own blood type can be better to understand yourself and your body. The purpose of the article. In Article studies on the history of medicine, which form new ones, are considered ideas about the formation of blood groups. The novelty of the study due to the fact that the idea of ​​blood groups from year to year replenished with new data, which encourages the historical sketch. Main part. With increasing population and changing the environment reduces the possibility to get meat food. As a result, this led to the emergence "Vegetarian" second blood group A. Resettlement of peoples in Europe is the reason for the predominance of people with the second blood group there at this time. It is believed that the homeland of the gene of the third group B is located in the foothills of the Himalayas, in present-day India and Pakistan. The fourth blood group AB arose as a result of mixing holders of gene A and carriers of gene B. Today only 6% Europeans have a fourth blood type, which is the youngest in ABO system. The uniqueness of this group in the inheritance of high immunological protection, which is manifested in resistance to autoimmune and allergic diseases. Conclusions. Evolution human is impossible without a systematic change in gene frequencies population. Is evolution continuing now? Thoughts sometimes contradictory. Some believe that man has reached the top evolutionary tree, others disagree with such conclusions.

2024 ◽  
Vol 84 ◽  
Author(s):  
M. Ghafar ◽  
S. Khwaja ◽  
M. Zahid ◽  
S. I. Hussain ◽  
A. Karim ◽  
...  

Abstract The main purpose of this study was to find out a possible association between ABO blood groups or Rh and diabetes mellitus (DM) in the local population of eight (8) different towns of Karachi, Pakistan. For this purpose a survey was carried out in Karachi to have a practical observation of these towns during the period of 9 months from June 2019 to Feb. 2020. Out of eighteen (18) towns of Karachi, samples (N= 584) were collected from only eight (8) Towns of Karachi and gave a code-number to each town. Diabetic group sample was (n1=432) & pre-diabetes sample was (n2 =152). A standard Abbot Company Glucometer for Random Blood Sugar (RBS) and Fasting Blood Sugar (FBS) tests, standard blood anti sera were used for ABO/Rh blood type. Health assessment techniques were performed ethically by taking informed consent from all registered subjects. Finally data was analyzed by SPSS version 20.0. In our current study, the comparison of ABO blood groups frequencies between diabetic and pre-diabetic individuals were carried out. The percentage values of blood Group-B as given as: (32% in DM vs. 31% in pre-diabetics), followed by blood Group-O as: (18% in DM vs. 11% in pre-diabetics). Contrary to Group-“B” & “O”, blood Group-A and Group-AB were distribution percentage higher pre-diabetic as compared to DM patients, as given as: Group-A (32% in pre-diabetics vs. 26% in DM) & Group-AB (26% in pre-diabetics vs. 24% in diabetic’s patients). In addition, percentage distribution of Rh system was also calculated, in which Rh+ve Group was high and more common in DM patients as compared to pre-diabetics; numerically given as: Rh+ve Group (80% in DM vs. 72% in pre-diabetics). Different views and dimensions of the research topic were studied through literature support, some have found no any association and some established a positive association still some were not clear in making a solid conclusion. It is concluded that DM has a positive correlation with ABO blood groups, and people with Group-B have increased susceptibility to DM disease.


PLoS ONE ◽  
2021 ◽  
Vol 16 (12) ◽  
pp. e0261432
Author(s):  
Uzma Ishaq ◽  
Asmara Malik ◽  
Jahanzeb Malik ◽  
Asad Mehmood ◽  
Azhar Qureshi ◽  
...  

Introduction Coronavirus disease 2019 (COVID-19) is the ongoing pandemic with multitude of manifestations and association of ABO blood group in South-East Asian population needs to be explored. Methods It was a retrospective study of patients with COVID-19. Blood group A, B, O, and AB were identified in every participant, irrespective of their RH type and allotted groups 1, 2,3, and 4, respectively. Correlation between blood group and lab parameters was presented as histogram distributed among the four groups. Multivariate regression and logistic regression were used for inferential statistics. Results The cohort included 1067 patients: 521 (48.8%) participants had blood group O as the prevalent blood type. Overall, 10.6% COVID-19-related mortality was observed at our center. Mortality was 13.9% in blood group A, 9.5% in group B, 10% in group C, and 10.2% in AB blood group (p = 0.412). IL-6 was elevated in blood group A (median [IQR]: 23.6 [17.5,43.8]), Procalcitonin in blood group B (median [IQR]: 0.54 [0.3,0.7]), D-dimers and CRP in group AB (median [IQR]: 21.5 [9,34]; 24 [9,49], respectively). Regarding severity of COVID-19 disease, no statistical difference was seen between the blood groups. Alteration of the acute phase reactants was not positively associated with any specific blood type. Conclusion In conclusion, this investigation did not show significant association of blood groups with severity and of COVID-19 disease and COVID-19-associated mortality.


Author(s):  
Melek Yanaşık ◽  
Tülin Tunç ◽  
Mukadder Huslu ◽  
Sevgi Kalayoğlu Beşışık

Objective: In humans, 38 different critical blood type classification systems are currently recognized. They differ in frequencies in distinct populations. It is aimed to visualize ABO and Rh(D) groups distribution in Istanbul as having the largest community in Turkey. Method: Volunteered blood donor's data on the automation system were screened retrospectively. Blood donation acceptance criteria were based on the guidelines prepared by the Ministry of Health. ABO and Rh(D) groups were analyzed using column agglutination/gel centrifugation methods. Results: The study covered six years' data between the dates of January 2014 and December 2019, including 136,231 donors. The majority of the donors were found to have blood group A with a frequency of 41.88%(n=57,059). The second most common blood group was group O, and had a frequency of 34.92%(n=47,576). The blood group B (n=20,790;15.26%) and group AB (n=10,806;7.93%) were found to be the rare encountered blood groups. Among the Rh(D) group, 85.02% of the donors were Rh(D) positive. Conclusion: In transfusion medicine, ABO and Rh(D) groups' compatibility is mandatory. According to the monthly and or annual blood products requirement, there are some suggested quantities of blood units to be available at blood centres. Determining the frequency of blood group distribution of populations will help to coordinate the ratio of blood groups to be storaged. The Turkish genetic makeup is a fascinating mixture of European and Asian DNA, necessitates to find out the countries' specific ABO and Rh(D) groups ratio. We compared our results with the previously reported studies performed in different cities of Turkey and the world around. Thus, our research as giving the overall distribution of ABO and Rh(D) groups from the largest city of Turkey reflecting the general ethnic background of the country, would help to the establishment of a databank of ABO and Rh(D) group's ratio.


2021 ◽  
Author(s):  
Nazaneen Omer ◽  
Sarwer Ismael ◽  
Heshu Sulaiman Rahman ◽  
Maryam Mohammed

Abstract Background ABO blood group types are among the risk factors of COVID-19 infection in many recent studies. Thus, the objective of this study is to find the relations between ABO types and COVID-19 infection as well as to find out the riskier group that is associated with hospitalization and the need for O2 support. Methods This observational cross-sectional study was done to identify the risk and relations between ABO blood groups and Rh factor of 530 Iraqi-Kurdish patients affected with COVID-19 infection. Among them, 184 patients were severe cases that needed hospitalization while 346 patients were mild to moderate cases that were treated at home. The diagnosis of COVID-19 infection was based on Real-Time Polymerase Chain Reaction (RT-PCR) test, high-resolution Chest CT scan, strong clinical suspicion plus history of the close home or job contact with COVID-19 confirmed patient. Results There were no significant differences in the distribution of ABO blood grouping in the total COVID-19 cases, however, the severity in form of hospitalization and O2 demand was higher in blood group A whereas the lowest in group B. Male patient were significantly older than females with more prolonged illness duration. The duration of COVID-19 illness, the need for plasma, and the rate of mortality were very significantly higher among hospitalized COVID-19 patients than non-hospitalized. In 37.2% of the patient, the initial presentation was a combination of more than one symptom. In 28% of cases, myalgia was the 1st mono-symptomatic presentation. Conclusions Blood group A is associated with the highest rate of hospitalization and O2 demand, besides, the duration of illness and rate of mortality in males were more than females.


2000 ◽  
Vol 6 (1) ◽  
pp. 156-158
Author(s):  
T. Pramanik ◽  
S. Pramanik

The frequencies of ABO and rhesus blood groups vary from one population to another. We studied blood group distribution in 120 Nepalese students; 34% were blood group A, 29% group B, 4% group AB and 32.5% group O. The frequency of Rh-negative blood was 3.33% and Rh-positive 96.66%


Author(s):  
Klaus Fiedler

The SARS-CoV-2 pandemic has resulted in the generation of evolutionary-related variants. The S-protein of the B.1.1.7 variant (deletion N-terminal domain (NTD) His69Val70Tyr144) may contribute to altered infectivity. These mutations may have been presaged by animal mutations in minks housed in mink farms that according to the present analysis by modelling of protein ligand docking altered a high affinity binding site in the S-protein NTD. These mutants likely occurred only sporadically in humans. Tissue-adaptations and the size of the mink relative to the infected human population size back then may have comparatively increased the relative mutation rate. Simple, multi-threaded automated docking that is widely available, assigns increased binding of the blood type II A antigen to the SARS-Cov-2 S-protein NTD of B.1.1.7 with an overall increased docking interaction of blood group A harbouring glycolipids relative to group B or H (H, p=0.04). The top scoring glycan is identified as a DSGG (also classified as sialosyl-MSGG or disialosyl-Gb5) that may compete with heparin, which is similar to heparan sulfate linked to proteinaceous receptors on the tissue surface. Other glycolipids are found to interact with lower affinity, except long ligands that have suitable ligand binding poses to match the curved binding pocket.


2008 ◽  
Vol 41 (02) ◽  
pp. 138-140
Author(s):  
Rasoul Gheisari ◽  
Mehdi Ghoreishian ◽  
Movahedian Bijan ◽  
Roozbehi Amrolah

ABSTRACT Background: Blood group is a genetic characteristic which is associated with some diseases and deformities. Multifactorial characteristics of facial development make it difficult to predict a genetic pattern in a specific maxillofacial deformity, but epidemiological evaluations can reveal relationships between such deformities and some genetic characteristics or accompanied diseases, and this will help to recognise and treat them. The aim of this study is evaluation of the relationship between blood groups and maxillofacial deformities. Materials and Methods: In this study, blood groups of 190 patients with maxillofacial deformities who had had orthognathic surgery in Alzahra hospital, Isfahan, were compared with the general Iranian population. Results: Among 190 patients, 93 cases (49%) were men and 97 cases (51%) were women. Fifteen cases (8%) were < 20 years old, 130 cases (68%) were 20-30 years old, and the others (45 cases, 24%) were > 30 years old. The blood group distribution in our samples was as follows: blood group O = 76 cases (40%), blood group A = 58 cases (30%), blood group B = 41 cases (22%), and blood group AB = 15 cases (8%). Among these patients, 31 cases (16%) had maxillary deformities and 27 cases (14%) suffered from mandibular deformities while the other 132 cases (70%) had bimaxillary problems. The Chi-square test showed statistically significant differences between the blood group distribution of the patients of this study and the normal Iranian population ( P < 0.001). Conclusion: It was shown that among different blood groups; those with blood group B have a greater likelihood of association with maxillofacial deformities. On the other hand, the probability of the association of such deformities was the least with blood group A.


2020 ◽  
Vol 10 (03) ◽  
pp. 421-425
Author(s):  
Suad Azeez Hassan ◽  
Suhair Hassan Alkutbi ◽  
Eman S. Nassir ◽  
Haider Hassan Lilo

Hepatitis B virus (HBV) and hepatitis C virus (HCV) infections are counted as a public health issue worldwide. The virus is transmitted to infect others through blood and blood products. Appointed blood groups and Rh-positive are more prone to the transmission of the infection by blood transfusion. The aim of this study is to find out the frequency of hepatitis B and C in apparently healthy blood donors and whether there is an association between ABO and Rh blood groups. ABO blood groups and their relationship with HBV and HCV infections were studied in 87,124 blood donors of both genders. Out of these donors, 353 individuals were found to be infected with HBV and HCV with a ratio of 1:250. The study was conducted between January to June 2018, which was presented to the Central Blood Bank in Baghdad and Al-Razi Medical Centre. It found that most hepatitis B and C blood donors were blood group O with a prevalence of 33.7 and 45.5%, respectively, while the results for those with blood group A showed 28.5 and 22.7% HBV and HCV infections, respectively. On the other hand, the incidence of HBV in individuals with blood group B was 29.8%, and HCV was 23.8%. AB blood group donors demonstrated the least incidence at 7.9% for both HBV and HCV. In conclusion, it has been found that there is a significant association between blood groups and Rh factor with hepatitis B and C infections.


2016 ◽  
Vol 23 (08) ◽  
pp. 1001-1004
Author(s):  
Naila Parveen ◽  
Javeria Rehman ◽  
Syed Hafeezul Hassan ◽  
Zoya Hassan ◽  
Madiha Rehman

Objectives: To find out the association of body mass index with different bloodgroups in medical students. Background: Increased body mass index leads to obesity and is aprominent risk factor for hypertension and diabetes. Blood groups are known to be associatedwith various diseases and recent studies have shown that a particular blood group with thehighest body mass index appeared to be more susceptible to predisposition to hypertension.Study Design: Cross-sectional study. Setting: Liaquat National Medical College, Karachi.Period: June 2015 to September 2015. Methodology: 181 medical students with 85 malesand 96 females and age ranging from 18-22 years. Weight and height of each student wasmeasured using the standard stadiometer and blood groups were determined using the antisera.Results: Mean age of the participants was 19.92 ± 1.10 years. Blood group “O” wasfound to be most prevalent (39.2%) while blood group “AB” was found to be the least (8.3%).Mean BMI of subjects with blood group A, B, AB and O were found to be 24.3 ± 5.04, 22.6 ±3.59, 23.0 ± 2.91 and 23.7 ± 4.20 kg/m2 respectively. The highest BMI was found in subjectswith blood group “A” 24.3 ± 5.04 kg/m2 and lowest in blood group “AB” 23.0 ± 2.91kg/m2. TheRhesus-D positive and male students had greater body mass index 23.6 ± 3.56 than females23.2 ± 3.44. Comparison of overall mean BMI values among different blood groups showedsignificant difference with p-value < 0.001. Conclusion: Blood group “A” and Rhesus-D positivesubjects especially males were found to be the high risk blood type with predisposition tomorbidity associated with increased body mass index.


Author(s):  
A. B. Ibrahim ◽  
H. Attahiru ◽  
O. Erhabor ◽  
P. F. Udomah ◽  
A. Yakubu ◽  
...  

ABO, Rhesus D and subgroups of ABO are highly immunogenic and are the common cause of antibody production in mismatched blood transfusions, haemolytic transfusion reaction and maternal alloimmunization. The aim of this study was to determine the occurrence of ABO, Rh D and subgroups of ABO among blood donors attending Specialist Hospital Sokoto, Nigeria. ABO, Rhesus D and subgroups of ABO antigen status of 176 blood donors with mean age of 30.44 ± 8.210 years attending Specialist Hospital Sokoto were determined using tile method for ABO and Rh D and conventional tube method for anti- A1, anti- H reagents for ABO subgroups respectively. Among the 176 subjects tested, blood group O+ was the most frequent group with 93 (52.8%), 39 (22.2%) were blood group B+, 37(21.0%) were blood group A+, 5 (2.8%) were blood group AB+, 2 (1.1%) were blood group O-. No data was obtained for A-, B- and AB- blood groups.  Out of 37 A blood groups obtained, 31 (83.8%) had A1 antigens and 6 (16.2%) had A2 antigens. Out of the 5 AB blood groups, all had A1B antigens. The study also shows that there was statistically significant difference between blood group A and ethnic groups (Hausa, Fulani and Yoruba) (p<0.05). Blood group O was found to be the most frequent followed by B, A and AB except among Hausa which revealed a pattern of O> A> B> AB. ABO, subgroups shows majority had A1 followed by A2 and A1B respectively.


Sign in / Sign up

Export Citation Format

Share Document