SPION size dependent effects on normal and cancer cells

2017 ◽  
Vol 62 (1) ◽  
pp. 29-42 ◽  
Author(s):  
Sergiu Gabriel Macavei ◽  
◽  
Maria Suciu ◽  
Izabell Crăciunescu ◽  
Lucian Barbu-Tudoran ◽  
...  
Keyword(s):  
Cancer Cells ◽  
Size Dependent

scholarly journals Size-Dependent Thermotherapy of Iron Oxide Nanoparticles on Human Breast Adenocarcinoma Cancer Cells

2013 ◽  
Vol 19 (S2) ◽  
pp. 218-219
Author(s):  
T. Mustafa ◽  
Y. Xu ◽  
F. Watanabe ◽  
Y. Zhang ◽  
M. Asar ◽  
...  
Keyword(s):  
Iron Oxide ◽  
Cancer Cells ◽  
Iron Oxide Nanoparticles ◽  
Breast Adenocarcinoma ◽  
Oxide Nanoparticles ◽  
Human Breast ◽  
Size Dependent ◽  
Human Breast Adenocarcinoma

Extended abstract of a paper presented at Microscopy and Microanalysis 2013 in Indianapolis, Indiana, USA, August 4 – August 8, 2013.

scholarly journals Size dependent anti-invasiveness of silver nanoparticles in lung cancer cells

RSC Advances ◽  
2019 ◽  
Vol 9 (37) ◽  
pp. 21134-21138 ◽  
Author(s):  
Yu Mei Que ◽  
Xiao Qing Fan ◽  
Xiao Juan Lin ◽  
Xiao Li Jiang ◽  
Ping Ping Hu ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Silver Nanoparticles ◽  
Cancer Cells ◽  
Elevated Level ◽  
A549 Cells ◽  
Migration And Invasion ◽  
Size Dependent ◽  
Adenocarcinoma Cells ◽  
Lung Adenocarcinoma Cells ◽  
A549 Lung

Size-dependent anti-invasiveness effect of AgNPs was determined using A549 lung adenocarcinoma cells. The 13 nm AgNPs can significantly inhibit the migration and invasion of A549 cells and induce the elevated level of ROS and NF-κB directed cell apoptosis.

scholarly journals Size-Dependent Photodynamic Anticancer Activity of Biocompatible Multifunctional Magnetic Submicron Particles in Prostate Cancer Cells

Molecules ◽  
2016 ◽  
Vol 21 (9) ◽  
pp. 1187 ◽  
Author(s):  
Kyong-Hoon Choi ◽  
Ki Nam ◽  
Leszek Malkinski ◽  
Eun Choi ◽  
Jin-Seung Jung ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Anticancer Activity ◽  
Cancer Cells ◽  
Submicron Particles ◽  
Prostate Cancer Cells ◽  
Size Dependent

scholarly journals Molecular size-dependent specificity of hyaluronan on functional properties, morphology and matrix composition of mammary cancer cells

2019 ◽  
Vol 3 ◽  
pp. 100008 ◽  
Author(s):  
Anastasia-Gerasimoula Tavianatou ◽  
Zoi Piperigkou ◽  
Carlo Barbera ◽  
Riccardo Beninatto ◽  
Valentina Masola ◽  
...  
Keyword(s):  
Cancer Cells ◽  
Functional Properties ◽  
Mammary Cancer ◽  
Molecular Size ◽  
Matrix Composition ◽  
Size Dependent ◽  
Mammary Cancer Cells

scholarly journals Self-assembled Pt2L2 boxes strongly bind G-quadruplex DNA and influence gene expression in cancer cells

2017 ◽  
Vol 46 (2) ◽  
pp. 329-332 ◽  
Author(s):  
O. Domarco ◽  
D. Lötsch ◽  
J. Schreiber ◽  
C. Dinhof ◽  
S. Van Schoonhoven ◽  
...  
Keyword(s):  
Gene Expression ◽  
Cancer Cells ◽  
Quadruplex Dna ◽  
Dna Motifs ◽  
Size Dependent ◽  
G Quadruplex ◽  
Self Assembled ◽  
Influence Gene Expression

Pt(ii) boxes bind native and G-quadruplex DNA motifs in a size-dependent fashion and influence the expression of G-quadruplex forming genes.

Size-dependent properties of M-PEIs nanogels for gene delivery in cancer cells

2007 ◽  
Vol 338 (1-2) ◽  
pp. 291-296 ◽  
Author(s):  
Dong-Mei Xu ◽  
Si-De Yao ◽  
Yong-Biao Liu ◽  
Kang-Long Sheng ◽  
Jun Hong ◽  
...  
Keyword(s):  
Gene Delivery ◽  
Cancer Cells ◽  
Size Dependent

Size-Dependent Biological Activities of Fluorescent Organosilane-Modified Zinc Oxide Nanoparticles

2020 ◽  
Vol 16 (2) ◽  
pp. 137-152
Author(s):  
Mariana Buşilă ◽  
Aurel Tăbăcaru ◽  
Viorica Muşsat ◽  
Bogdan Ştefan Vasile ◽  
Ionela Andreea Neaşu ◽  
...  
Keyword(s):  
Electron Microscopy ◽  
Transmission Electron Microscopy ◽  
Zinc Oxide ◽  
Cancer Cells ◽  
Zinc Oxide Nanoparticles ◽  
Oxide Nanoparticles ◽  
Cytotoxic Activities ◽  
Zno Nps ◽  
Size Dependent ◽  
Transmission Electron

Surface modification of zinc oxide nanoparticles (ZnO NPs) is a strategy to tune their biocompatibility. Herein we report on the synthesis of a series of fluorescent ZnO NPs modified with 2–10% (3-glycidyloxypropyl)trimethoxysilane (GPTMS) to investigate the fluorescence properties and to explore their applications in microbiology and biomedicine. The obtained ZnO NPs were characterized by X-ray diffraction (XRD), high resolution transmission electron microscopy (HRTEM) and Fourier transform infrared spectroscopy (FTIR). Size reduction occurred from ca. 13 nm in unmodified ZnO to 3–4 nm in silane-modified samples and fluorescence spectra showed size-dependent variation of the photoemission bands' intensity. The antibacterial and cytotoxic activities were investigated on Gram-negative (Escherichia coli) and Gram-positive (Staphylococcus aureus) bacteria, and in ovarian (A2780) and prostate (PC3) cancer cells by tetrazolium/formazan-based methods. The antibacterial effect was higher for E. coli than S. aureus, while the cytotoxic activity was similar for both cancer cells and varied with the particle size. Cell death by apoptosis, and/or necrosis versus autophagy, were explored by flow cytometry using an Annexin V based-method and transmission electron microscopy (TEM). The main mechanism of ZnO NPs toxicity may involve the generation of reactive oxygen species (ROS) and the induction of apoptosis or autophagy. This work revealed the potential utility of GPTMS-modified ZnO NPs in the treatment of bacterial infection and cancer.

scholarly journals Size-Dependent Localization and Penetration of Ultrasmall Gold Nanoparticles in Cancer Cells, Multicellular Spheroids, and Tumors in Vivo

ACS Nano ◽  
2012 ◽  
Vol 6 (5) ◽  
pp. 4483-4493 ◽  
Author(s):  
Keyang Huang ◽  
Huili Ma ◽  
Juan Liu ◽  
Shuaidong Huo ◽  
Anil Kumar ◽  
...  
Keyword(s):  
Gold Nanoparticles ◽  
Cancer Cells ◽  
Multicellular Spheroids ◽  
Size Dependent

Production and STEM examination of controlled-size silver clusters

1983 ◽  
Vol 41 ◽  
pp. 338-339
Author(s):  
M. A. Listvan ◽  
R. P. Andres
Keyword(s):  
Cluster Size ◽  
Metal Clusters ◽  
Experimental Parameter ◽  
Carbon Films ◽  
Metal Species ◽  
Silver Clusters ◽  
Free Jet ◽  
Size Dependent ◽  
Cluster Properties ◽  
Controllable Size

Knowledge of the function and structure of small metal clusters is one goal of research in catalysis. One important experimental parameter is cluster size. Ideally, one would like to produce metal clusters of regulated size in order to characterize size-dependent cluster properties.A source has been developed which is capable of producing microscopic metal clusters of controllable size (in the range 5-500 atoms) This source, the Multiple Expansion Cluster Source, with a Free Jet Deceleration Filter (MECS/FJDF) operates as follows. The bulk metal is heated in an oven to give controlled concentrations of monomer and dimer which were expanded sonically. These metal species were quenched and condensed in He and filtered to produce areosol particles of a controlled size as verified by mass spectrometer measurements. The clusters were caught on pre-mounted, clean carbon films. The grids were then transferred in air for microscopic examination. MECS/FJDF was used to produce two different sizes of silver clusters for this study: nominally Ag6 and Ag50.

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