The outline of naming process, anatomy and histopathology of infraorbital dark circles

Infraorbital dark circle,previously known as allergic shiners.The pathogenesis,the swollen turbinate compressing the sphenopalatine vein plexus,causing venous congestion of eyelid vein and the canthus in eyes,is unattested.This article studies the anatomical structure under the orbital part.It is believed that the mechanism is more closely related to the backflow obstruction of infraorbital vein.Besides,it may also be the causes of infraorbital dark circle of local congestion of infraorbital space and inferior orbital lymph nodes backflow blocked.Finally, the histopathological findings of some aesthetic medicine are reviewed.

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Clinical Features, Histopathology and Differential Diagnosis of Sarcoidosis

Cells ◽

10.3390/cells11010059 ◽

2021 ◽

Vol 11 (1) ◽

pp. 59

Author(s):

Claudio Tana ◽

Iginio Donatiello ◽

Alessandro Caputo ◽

Marco Tana ◽

Teresa Naccarelli ◽

...

Keyword(s):

Differential Diagnosis ◽

Clinical Practice ◽

Lymph Nodes ◽

Clinical Features ◽

Routine Clinical Practice ◽

The Other ◽

Unknown Etiology ◽

Histopathological Findings ◽

Clinical Pictures ◽

Granulomatous Disorders

Sarcoidosis is a chameleon disease of unknown etiology, characterized by the growth of non-necrotizing and non-caseating granulomas and manifesting with clinical pictures that vary on the basis of the organs that are mainly affected. Lungs and intrathoracic lymph nodes are the sites that are most often involved, but virtually no organ is spared from this disease. Histopathology is distinctive but not pathognomonic, since the findings can be found also in other granulomatous disorders. The knowledge of these findings is important because it could be helpful to differentiate sarcoidosis from the other granulomatous-related diseases. This review aims at illustrating the main clinical and histopathological findings that could help clinicians in their routine clinical practice.

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Correlation Between FNAC and Open Biopsy in Cervical Lymhadenopathy in Children

Journal of Paediatric Surgeons of Bangladesh ◽

10.3329/jpsb.v1i2.19526 ◽

2014 ◽

Vol 1 (2) ◽

pp. 118-126

Author(s):

Tahmina Hossain ◽

Md. Ruhul Amin ◽

MTH Siddiqui ◽

Md. Ashraf Ul Huq ◽

Md. Matiur Rahman

Keyword(s):

Lymph Nodes ◽

False Positive ◽

False Negative ◽

Neck Region ◽

The Body ◽

Clinical Impression ◽

Open Biopsy ◽

Surgical Biopsy ◽

Cervical Lymph Nodes ◽

Histopathological Findings

Background: Head and Neck region of the body has a rich network of lymphatic channel and intervening nodes. Out of total approximately 800 lymph nodes in the body about 300 are scattered in organized fashion in the neck region which are affected by various regional and systemic diseases. The conventional method of excisional biopsy is used to diagnose etiological causes of lymphadenopathy. In comparison to open surgical biopsy, FNAC is a simple, reliable and acceptable tool for the etiological diagnosis of lymphadenopathies. FNAC was first practiced by Grieg and Gray for the diagnosis of trypanosome in lymphnode in 1904. Now a day it is widely practiced in United States, United Kingdom and many other countries. In Bangladesh, many studies on FNAC are carried out and the results are highly appreciable and reliable.Methods: A prospective study for a period of 24 months was carried out on 50 patients with enlarged cervical lymph nodes from July 2003 to June 2005. During the two years study period, 56 patients with cervical lymphadenopathies were selected for FNAC and openbiopsy following certain inclusion and exclusion criteria, in the Department of Pediatric Surgery, Bangabandhu Sheikh Mujiib Medical University, Dhaka. Patients with acute lymphadenitis and lymphadenopathy due to leukaemia were excluded. Six cases were deleted from the study as smears from those revealed inadequate material and hence only 50 cases were available for study in the present series. Clinical findings, FNAC and biopsy reports were available in all the cases and were correlated with each other.Results: On biopsy, 27 cases were diagnosed as tuberculous lymphadenopathies, 15 cases as lymphoma and 8 cases as reactive changes. On FNAC, there were 2 false positive and 5 false negative cases in case of tuberculosis; 2 false positive and 1 false negative cases in lymphoma; 4 false positive and 2 false negative cases in cases with reactive hyperplasia. Sensitivity of FNAC in comparison to histopathological findings was 92.6% in case of tuberculosis; 86.7% in case of lymphoma and 50% in case of nonspecific lymphadenitis. Specificity of FNAC in comparison to histological findings was 78.3% in case of tuberculosis; 94.2% in case of lymphoma and 95.3% in case of nonspecific lymphadenitis. Accuracy of FNAC in comparison to histopathological findings was 86% in case of tuberculosis; 94% in case of lymphoma and 88% in case of reactive changes.Conclusions: The present study indicates that, FNAC is a simple, reliable and acceptable procedure for various lesions of cervical lymph nodes. It can be repeated if necessary. It also concludes that FNAC helps to confirm the clinical impression without open biopsy. Open biopsy can be avoided in many benign and malignant lesions of cervical lymph nodes. Fine needle aspiration cytodiagnosis can eliminate the need of hospitalization and surgery.DOI: http://dx.doi.org/10.3329/jpsb.v1i2.19526

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Spontaneously Identified Gastric Sarcoidosis: A Report of Three Cases

Journal of International Medical Research ◽

10.1177/147323000303100312 ◽

2003 ◽

Vol 31 (3) ◽

pp. 239-243 ◽

Cited By ~ 8

Author(s):

K Kawaura ◽

T Takahashi ◽

K Kusaka ◽

J Yamakawa ◽

T Itoh ◽

...

Keyword(s):

Lymph Nodes ◽

Histological Analysis ◽

Partial Gastrectomy ◽

Abdominal Discomfort ◽

Accurate Diagnosis ◽

Granulomatous Disease ◽

Mucosal Biopsy ◽

Histopathological Findings ◽

Mucosal Changes

Sarcoidosis is a systemic granulomatous disease, frequently involving the lungs, lymph nodes, eyes and skin. Gastric sarcoidosis is very rare. We report three patients diagnosed initially with gastric sarcoidosis. Two had no other identified involvement, and one had involvement of the lungs and hilar lymph nodes. Gastroscopy was performed because of abdominal discomfort or as a follow-up examination for partial gastrectomy. This revealed atrophic lesions with nodular mucosal changes in the antrum and granular mucosa, and residual gastritis was found at the site of gastroduodenal anastomosis. Non-caseating epitheloid-cell granulomas were found in all patients following histological analysis. Gastroscopy and histopathological findings in gastric mucosal biopsy samples from suspicious sites are essential in establishing an accurate diagnosis of gastric sarcoidosis.

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HIGH CONCENTRATION OF INJECTED TITANIUM DIOXIDE IN ABDOMINAL LYMPH NODES

Journal of Experimental Medicine ◽

10.1084/jem.124.6.1099 ◽

1966 ◽

Vol 124 (6) ◽

pp. 1099-1106 ◽

Cited By ~ 24

Author(s):

Charles B. Huggins ◽

Jeffrey P. Froehlich

Keyword(s):

Titanium Dioxide ◽

Particulate Matter ◽

Lymph Nodes ◽

Intravenous Injection ◽

Quantitative Characteristic ◽

Anatomical Structure ◽

High Concentration ◽

Upper Abdomen ◽

Small Clusters

In the rat the greatest accumulation, in any anatomical structure, of titanium dioxide following its intravenous injection was found in two small clusters of lymph nodes in upper abdomen behind the peritoneum. These are the lymph nodes of the liver. This extraordinary quantitative characteristic of the abdominal clusters is attributed to their topography which results in progressive filtration of particulate matter from hepatic lymph.

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Association between contrast-enhanced ultrasonography and histopathological findings of the metastatic lymph nodes of patients with head and neck cancer: A preliminary study

Oncology Letters ◽

10.3892/ol.2018.7835 ◽

2018 ◽

Author(s):

Shin‑Ichi Oikawa ◽

Kiyoto Shiga ◽

Daisuke Saito ◽

Katsunori Katagiri ◽

Aya Ikeda ◽

...

Keyword(s):

Head And Neck Cancer ◽

Lymph Nodes ◽

Head And Neck ◽

Neck Cancer ◽

Metastatic Lymph Nodes ◽

Histopathological Findings ◽

Metastatic Lymph ◽

Contrast Enhanced ◽

Contrast Enhanced Ultrasonography ◽

Preliminary Study

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Scanning electron microscopy of freeze-fractured prescapular lymph node of caprine

Proceedings, annual meeting, Electron Microscopy Society of America ◽

10.1017/s0424820100111331 ◽

1984 ◽

Vol 42 ◽

pp. 244-245

Author(s):

O. Faroon ◽

F. Al-Bagdadi ◽

T. G. Snider ◽

C. Titkemeyer

Keyword(s):

Lymph Node ◽

Lymph Nodes ◽

Lymphatic System ◽

Three Dimensional ◽

Meat Products ◽

The Body ◽

Morphological Data ◽

The World ◽

Cellular Constituent ◽

Scanning Electron

The lymphatic system is very important in the immunological activities of the body. Clinicians confirm the diagnosis of infectious diseases by palpating the involved cutaneous lymph node for changes in size, heat, and consistency. Clinical pathologists diagnose systemic diseases through biopsies of superficial lymph nodes. In many parts of the world the goat is considered as an important source of milk and meat products.The lymphatic system has been studied extensively. These studies lack precise information on the natural morphology of the lymph nodes and their vascular and cellular constituent. This is due to using improper technique for such studies. A few studies used the SEM, conducted by cutting the lymph node with a blade. The morphological data collected by this method are artificial and do not reflect the normal three dimensional surface of the examined area of the lymph node. SEM has been used to study the lymph vessels and lymph nodes of different animals. No information on the cutaneous lymph nodes of the goat has ever been collected using the scanning electron microscope.

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Ultrastructure of the lesion induced by toxin T-514 isolated from K. humboldtiana in the alveolar region of the lung

Proceedings, annual meeting, Electron Microscopy Society of America ◽

10.1017/s042482010012360x ◽

1992 ◽

Vol 50 (1) ◽

pp. 640-641

Author(s):

Julio Sepúlveda-Saavedra ◽

Beatriz González-Corona ◽

Víctor A. Tamez Rodríguez ◽

Ma. Victoria Bermúdez de Rocha ◽

Alfredo Piñeyro López

Keyword(s):

Electron Microscope ◽

Guinea Pig ◽

Macaca Fascicularis ◽

Osmium Tetroxide ◽

Lead Citrate ◽

Severe Damage ◽

Thin Sections ◽

Alveolar Region ◽

Histopathological Findings

It has been shown in previous studies that the toxin T-514 isolated from K. humboldtiana induces severe damage to the lung in treated rodents. Histopathological findings include edema, and alveolar hemorrage. However, the ultraestructure of the lesion has not been investigated. In this study we used two species of rodents: Hamster and guinea pig, and a primate: Macaca fascicularis. Animals received different single dosis of the toxin via intraperitoneal. Control animals received only the vehicle (propylen glycol). Inmediately after spontaneous death, lung samples were fixed in Karnovsky-Ito fixative, post fixed in osmium tetroxide and embedded in epon. Thin sections were prepared with an Ultratome V LKB, stained with uranly acetate and lead citrate, and studied in an electron microscope Zeiss-EM109.

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Microvasculature and structure of hemal lymph nodes in the wall of the rabbit bladder: a vascular corrosion casting and EM study

Proceedings, annual meeting, Electron Microscopy Society of America ◽

10.1017/s0424820100141743 ◽

1995 ◽

Vol 53 ◽

pp. 1074-1075

Author(s):

F.E. Hossler ◽

M.I. McKamey ◽

F.C. Monson

Keyword(s):

Lymph Nodes ◽

Light Microscopy ◽

Corrosion Casting ◽

Fixed Tissue ◽

Infusion Pressure ◽

India Ink ◽

Cacodylate Buffer ◽

Rabbit Bladder ◽

Lateral Walls ◽

Comprehensive Study

A comprehensive study of the microvasculature of the normal rabbit bladder, revealed unusual "capillary glomeruli" along the lateral walls. Here they are characterized as hemal lymph nodes using light microscopy, SEM, TEM, ink injection, and vascular casting.Bladders were perfused via a cannula placed in the abdominal aorta with either 2% glutaraldehyde in 0.1M cacodylate buffer (pH 7.4) for fixation, 10% India ink in 0.9% saline and 0.1M phosphate (pH 7.4) for vessel tracing, or resin (Mercoximethylmethacrylate: catalyst, 4:1:0.3; Ladd Research Industries) for vascular corrosion casting. Infusion pressure was 100mm Hg. Fixed tissue was sectioned from epon-araldyte resin, and stained with toluidine blue for light microscopy, and lead and uranium for TEM. Ink injected tissue was photographed directly from saline-filled bladders illuminated from below. Resin-filled tissue was macerated in 5% KOH and distilled water. Casts were critical point dried, sputter coated with goldpalladium, and examined by routine SEM at 10 KV.

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