scholarly journals Towards the second edition of the book “QSAR-mapping and SBGN-Mapping for Biological Samples (Lecture Course and Special Practicum)”

2018 ◽  
Vol 1 (2) ◽  
Author(s):  
Oleg V. Gradov
Keyword(s):  
Biological Samples ◽  
Biomedical Applications ◽  
Field Of View ◽  
Dynamic Processes ◽  
The Novel ◽  
Technology Journal ◽  
Microscopic Imaging ◽  
Spatiotemporal Dynamic ◽  
Living State ◽  
Material Points

I am very glad to present to the readers of “Medical Imaging Process & Technology” journal the forthcoming second edition of our book “QSAR-mapping and SBGN-mapping for Biological Samples (Lecture Course and Special Practicum)”, which is actually an introduction to the novel microscopic imaging approaches for numerous biomedical applications. It is possible to imagine that imaging and morphology of biological structures is not a rigorous mapping of different “material points” and structures in the field of view (or ROI’s), because the living state of the sample is a complex of many spatiotemporal dynamic processes. 

Numerical analysis of non-aligned inputs M-type micromixers with different shaped obstacles for biomedical applications

2021 ◽  
pp. 095440892110516
Author(s):  
Muhammad Irfan ◽  
Imran Shah ◽  
Usama M Niazi ◽  
Muhsin Ali ◽  
Sadaqat Ali ◽  
...  
Keyword(s):  
Structural Design ◽  
Biomedical Applications ◽  
Structural Changes ◽  
Nanoparticle Synthesis ◽  
Fluid Mixing ◽  
The Novel ◽  
Flow Conditions ◽  
Mixing Index ◽  
Mixing Performance ◽  
Passive Micromixer

Fluid mixing in lab-on-a-chip devices at laminar flow conditions result in a low mixing index. The reason is dominant diffusion over the convection process. The mixing index can be improved by certain changes in the micromixer structural design like introducing obstacles in the path of fluid flow. These obstacles will make dominant the advection process over the diffusion process. The main contribution of this work is based on proposing the novel hybrid type micromixer design for enhancing the mixing quality. Three non-aligned M-type and non-aligned M-type with obstacles passive type micromixers are analyzed by COMSOL5.5. These designs are hybrid types because different structural changes are combined in a single design for mixing improvement. First of all the straight non-aligned inlets, M-type passive micromixer (SMTM) is analyzed. It is observed that mixing performance is improved because of M-shaped mixing units and non-aligned inlets. This improvement is deemed to be not enough so different shaped obstacles are introduced in the micromixer design. These designs based on obstacles are named horizontal rectangular M-type micromixer, square M-type micromixer, and vertical rectangular M-type micromixer. The mixing index for SMTM, square M-type micromixer, horizontal rectangular M-type micromixer, and vertical rectangular M-type micromixer at Reynolds number Re = 60 is respectively given by 71.1%, 83.21%, 84.45%, and 89.99%. The mixing index of vertical rectangular M-type micromixer was 59.34% − 87.65% for Re = 0.5–100. Vertical rectangular M-type micromixer is concluded with the better-mixing capability design among the proposed ones. Based on these simulation results, the vertical rectangular M-type micromixer design can be utilized for mixing purposes in biomedical applications like nanoparticle synthesis and biomedical sample preparation for drug delivery.

The effect on the fatigue strength of bone cement of adding sodium fluoride

2001 ◽  
Vol 215 (2) ◽  
pp. 251-253 ◽  
Author(s):  
C Minari ◽  
M Baleanil ◽  
L Cristofolini ◽  
F Baruffaldi
Keyword(s):  
Fatigue Strength ◽  
Bone Cement ◽  
Sodium Fluoride ◽  
Biomedical Applications ◽  
Cement Mantle ◽  
Fatigue Tests ◽  
Fatigue Performance ◽  
Bone Cements ◽  
The Novel ◽  
Pmma Bone Cement

New bone cements that include several additives are currently being investigated and tested. One such additive is sodium fluoride (NaF), which promotes bone formation, facilitating implant integration and success. The influence of NaF on the fatigue performance of the cement as used in biomedical applications was tested in this paper. In fact fatigue failure of the cement mantle is a major factor limiting the longevity of a cemented implant. An experimental bone cement with added NaF (12wt%) was investigated. The fatigue strength of the novel bone cement was evaluated in comparison with the cement without additives; fatigue tests were conducted according to current standards. The load levels were arranged based on a validated, statistically based optimization algorithm. The curve of stress against number of load cycles and the endurance limit were obtained and compared for both formulations. The results showed that the addition of NaF (12 wt %) to polymethylmethacrylate (PMMA) bone cement does not affect the fatigue resistance of the material. Sodium fluoride can safely be added to the bone cement without altering the fatigue performance of the PMMA bone cement.

scholarly journals FPM app: an open-source application for simple and intuitive Fourier ptychographic reconstruction

2021 ◽  
Author(s):  
Mikolaj Rogalski ◽  
Piotr Zdankowski ◽  
Maciej Trusiak
Keyword(s):  
Open Source ◽  
Graphical User Interface ◽  
Open Source Software ◽  
Field Of View ◽  
Large Field ◽  
Reconstruction Process ◽  
Microscopic Imaging ◽  
Microscopy Technique ◽  
Wide Scale ◽  
Noise Robust

Fourier ptychographic microscopy (FPM) is a computational microscopy technique that enables large field of view and high-resolution microscopic imaging of biological samples. However, the FPM does not yet have an adequately capable open-source software. In order to fill this gap we are presenting novel, simple, universal, semi-automatic and highly intuitive graphical user interface (GUI) open-source application called the FPM app enabling wide-scale robust FPM reconstruction. Apart from implementing the FPM in accessible GUI app, we also made several improvements in the FPM image reconstruction process itself, making the FPM more automatic, noise-robust and faster.

scholarly journals Fe3O4 Nanoparticle-Reinforced Magnesium Nanocomposites Processed via Disintegrated Melt Deposition and Turning-Induced Deformation Techniques

Metals ◽  
2019 ◽  
Vol 9 (11) ◽  
pp. 1225 ◽  
Author(s):  
Michael Johanes ◽  
Sravya Tekumalla ◽  
Manoj Gupta
Keyword(s):  
Biomedical Applications ◽  
Superparamagnetic Iron Oxide ◽  
The Novel ◽  
Metallic Materials ◽  
Turning Process ◽  
Recent Past ◽  
Deformation Method ◽  
Property Profile ◽  
Melt Deposition ◽  
Superior Property

Magnesium nanocomposites, with nano-scale ceramic reinforcements, have attracted a great deal of attention for several engineering and biomedical applications in the recent past. In this work, superparamagnetic iron oxide nanoparticles, Fe3O4, with their unique magnetic properties and the ability of being bio-compatible and non-toxic, are reinforced to magnesium to form Mg/(1, 2, and 3 wt %) Fe3O4 nanocomposites. These nanocomposites were fabricated using the conventional disintegrated melt deposition (DMD) technique followed by extrusion. Further, the materials were also processed using the novel turning-induced-deformation technique where the chips from turning process are collected, cold compacted, and hot extruded. The materials processed via the two techniques were compared in terms of microstructure and properties. Overall, the Mg/Fe3O4 nanocomposites, processed via both routes, exhibited a superior property profile. Further, the turning-induced deformation method showed promising results in terms of improved properties of the nanocomposites and serves as a great route for the recycling of metallic materials.

scholarly journals Hybrid magnetic nanoparticles as efficient nanoheaters in biomedical applications

2021 ◽  
Vol 3 (4) ◽  
pp. 867-888
Author(s):  
Gabriel C. Lavorato ◽  
Raja Das ◽  
Javier Alonso Masa ◽  
Manh-Huong Phan ◽  
Hariharan Srikanth
Keyword(s):  
Magnetic Nanoparticles ◽  
Biomedical Applications ◽  
The Novel ◽  
Heating Efficiency ◽  
Synthesis Routes

In this minireview we discuss and provide a perspective on the novel systems, the synthesis routes and the interface-mediated properties that determine the heating efficiency of hybrid magnetic nanoparticles.

Confocal Raman microscopic imaging of biological samples

1997 ◽  
Author(s):  
Serguei Charonov ◽  
Igor Chourpa ◽  
Paolo Valisa ◽  
Michel Manfait
Keyword(s):  
Biological Samples ◽  
Microscopic Imaging ◽  
Confocal Raman

scholarly journals Novel Catalytic Ceramic Conversion Treatment of Ti6Al4V for Improved Tribological and Antibacterial Properties for Biomedical Applications

Materials ◽  
2021 ◽  
Vol 14 (21) ◽  
pp. 6554
Author(s):  
James Alexander ◽  
Huan Dong ◽  
Deepa Bose ◽  
Ali Abdelhafeez Hassan ◽  
Sein Leung Soo ◽  
...  
Keyword(s):  
Electron Microscopy ◽  
Biomedical Applications ◽  
Antibacterial Properties ◽  
Oxide Thickness ◽  
The Novel ◽  
X Ray Diffraction ◽  
Wear Factor ◽  
Antibacterial Performance ◽  
Transmission Electron ◽  
Colony Forming Units

Titanium oxide layers were produced via a novel catalytic ceramic conversion treatment (CCCT, C3T) on Ti-6Al-4V. This CCCT process is carried out by applying thin catalytic films of silver and palladium onto the substrate before an already established traditional ceramic conversion treatment (CCT, C2T) is carried out. The layers were characterised using scanning electron microscopy, X-ray diffraction, transmission electron microscopy; surface micro-hardness and reciprocating tribological performance was assessed; antibacterial performance was also assessed with s. aureus. This CCCT has been shown to increase the oxide thickness from ~ 5 to ~ 100 µm, with the production of an aluminium rich layer and agglomerates of silver and palladium oxide surrounded by vanadium oxide at the surface. The wear factor was significantly reduced from ~ 393 to ~ 5 m3/N·m, and a significant reduction in the number of colony-forming units per ml of Staphylococcus aureus on the CCCT surfaces was observed. The potential of the novel C3T treatment has been demonstrated by comparing the performance of C3T treated and untreated Ti6Al4V fixation pins through inserting into simulated bone materials.

scholarly journals “The Life of Arsenyev, of Course, Is Primarily Poetry”: Georgy Adamovich on Ivan Bunin’s Novel, 1929–1952

Literary Fact ◽  
2021 ◽  
pp. 304-325
Author(s):  
Anton V. Bakuntsev
Keyword(s):  
New York ◽  
Comparative Analysis ◽  
Research Methods ◽  
Publishing House ◽  
Field Of View ◽  
The Novel ◽  
State Archive ◽  
Russian State ◽  
Empirical Material ◽  
Article Abstract

The author expresses his heartfelt gratitude to the staff of the Russian State Archive of Literature and Art, as well as to S.N. Morozov (IWL RAS) and S.R. Fedyakin (Gorky Literary Institute) for their assistance in the preparation of the article. Abstract: The article uses the material of G.V. Adamovich’s publications in emigrant periodicals to address the problem of critical reception of I.A. Bunin’s novel “The Life of Arsenyev” in the late 1920s – early 1950s. Bunin in 1928–1939 published his novel in parts. At the same time, the appearance in the magazine “Sovremennye zapiski” (Paris) of each of the five books included in the novel and the release of individual book editions were preceded by the publication of fragments of “The Life of Arsenyev” in emigrant newspapers. This explains the relatively large 324 Литературный факт. 2021. № 3 (21) number of Adamovich’s responses to Bunin's novel. The critic did not let “The Life of Arsenyev” out of his field of view from the time of the publication of her third book in “Sovremennye zapiski” (1929) until the first complete edition of the novel was published in the New York Chekhov Publishing House (1952). The article traces how Adamovich’s attitude to Bunin’s work was adjusted over the years, and how, as a result, sophisticated pickiness was replaced by unconditional admiration. The empirical material is grouped taking into account the chronology of the publication of “The Life of Arsenyev”. The research methods used are the principle of historicism and comparative analysis.

Characterization and Quick Screening Methodology of Novel Alloys for Biomedical Applications Using Filtered Cathodic Vacuum Arc Deposited Thin Film

2018 ◽  
Vol 283 ◽  
pp. 78-87
Author(s):  
Saran Tantavisut ◽  
Boonrat Lohwongwatana ◽  
Atchara Khamkongkaeo ◽  
Suparat Bootchai ◽  
Pairat Tangpornprasert ◽  
...  
Keyword(s):  
Thin Film ◽  
Amorphous Alloys ◽  
Biomedical Applications ◽  
Toxic Elements ◽  
Vacuum Arc ◽  
Induction Melting ◽  
The Novel ◽  
Cover Glass ◽  
Glass Slides ◽  
Filtered Cathodic Vacuum Arc

Ti-based amorphous alloys containing no harmful elements are desired. However, many Ti-based amorphous alloys contain toxic elements such as Al, Ni, V and Be. The presence of toxic elements within amorphous alloys is a concern when they are intended for use as a biomaterial. This problem has steered many researchers toward the development of Ti-based amorphous alloys without toxic elements. Our novel amorphous alloys were developed based on this principle. A series of Ti44Zr10Pd10Cu6+xCo23-xTa7 (x = 0, 4, 8) amorphous alloys were developed for biomedical application. A series of protocol tests were performed to check for biocompatibility and potential use of the novel alloys in humans. First, alloy ingots were alloyed by induction melting and then cast into copper molds. The cast rod was then used as the plasma cathode in a filtered cathodic vacuum arc deposition chamber to coat the 25-nm amorphous alloy thin film on the cover glass slides. These coated cover glass slides were then examined for biocompatibility. Cell proliferation and cell differentiation were investigated using Methylthiazol Tetrazolium assay test and by alkaline phosphatase assay on osteoblast like cells (SaOS-2), respectively. Field emission scanning electron microscopy was performed to evaluate the thin film surface characteristics. The thickness of thin film was analyzed using a Stylus profilometer. An adhesion scratch test was administered to evaluate the thin film adhesive strength and indirect hardness comparison. Electron Dispersive X-ray Spectrometry was performed to study the elemental composition. Lastly, a medical grade Ti-6Al-4V alloy was studied in parallel as a control material. Results indicated that all investigated Ti-based amorphous alloys were non-cytotoxic and were comparable to the Ti-6AL-4V. They also demonstrated an ability to support differentiation of osteoblast like cells. The adhesion and the hardness of the thin films on the substrates were superior to that of Ti-6Al-4V. The results suggested that the novel alloys in this study could be potentially utilized in biomedical applications.

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