There is represented to be relevant to clarify what personal characteristics contribute to the formation of fibro-cavernous tuberculosis, to prevent its formation in the course of treatment. The aim is to identify the personal features ofpatients with fibro-cavernous pulmonary tuberculosis to develop psychological support in the subsequent treatment of newly diagnosed patients, preventing the formation of chronic specific process. Material and methods. 96 patients participated in a study: 48 cases with fibro-cavernous tuberculosis and 48 healthy volunteers. To study the personality characteristics there was used «Combined Personality Inventory (CPI)» based on the Raymond Cattell’s 16 Personality Factors (adaptation by G.A. Leevik). Results. In comparison with the control group patients with fibro-cavernous pulmonary tuberculosis had higher averages in scales A (reserved demeanor - openness), F (poverty - wealth of emotional reactions), Н (reservedness - activity in communication), L (credulity - suspicion), M (practical - dreamy style of thinking), N (easy - the sophistication of behavior), O (confidence - lack of confidence), Q1 (conservatism - the desire for new), Q2 (conformity - non-conforming), Q4 (relaxed - alertness), P (plasticity - rigidity) and Tr (anxiety). They have reduced the level of logical intelligence, they are both less balanced and easier to subjugate, not disciplined, have low self-control, low level of claims, a less favorable climate in the family, coupled with introversion. Conclusion. Thus, patients with fibro-cavernous tuberculosis are distinguished by reservedness in communications, reserved demeanor, suspicion, alertness, anxiety, lack of discipline, poor self-control. Creation of a special social and psychological support services for this group ofpatients can elevate the efficiency of the complex treatment and improve prognosis.