Cognitive Impairment and Quality of Life among Stroke Survivors in Nigeria

2007 ◽  
Vol 100 (3) ◽  
pp. 876-882 ◽  
Author(s):  
Femi O. Fatoye ◽  
Morenikeji A. Komolafe ◽  
Benjamin A. Eegunranti ◽  
Abiodun O. Adewuya ◽  
Samuel K. Mosaku ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Cognitive Impairment ◽  
Cognitive Deficits ◽  
Poor Performance ◽  
Stroke Survivors ◽  
Life Questionnaire ◽  
Low Education ◽  
State Examination ◽  
Normal Controls

The study investigated cognitive impairment and quality of life (QOL) among 109 consecutive stroke survivors and 109 normal controls. Each group comprised 64 (58.7%) men and 45 (41.3%) women. The modified Mini Mental State Examination (mMMSE) and the WHO Quality of Life Questionnaire (WHOQOL-Bréf) indicated that 19 (17.4%) stroke survivors had cognitive deficits (mMMSE score < 16) compared with 5 (4.6%) control participants (χ12 = 4.27, p<.05). Control participants performed significantly better on orientation, language comprehension, laterality, and the WHOQOL-Bréf. Being GHQ-30 positive predicted poor performance on the mMMSE among the stroke survivors and reduced QOL on three of the four domains of the WHOQOL-Bréf. In addition, previous psychiatric illness, paresis, low education, and shorter time elapsed after a stroke predicted reduced QOL on one or more domains of the WHOQOL-Bréf but age and sex of the stroke survivors were not associated with quality of life, and not with cognitive function.

scholarly journals COGNITIVE IMPAIRMENT AND ITS IMPACT ON QUALITY OF LIFE IN RURAL INDIAN FEMALE AFTER STROKE: A CROSS SECTIONAL STUDY

2021 ◽  
Vol 10 (4) ◽  
pp. 3414-3416
Author(s):  
Nikita S. Deshmukh
Keyword(s):  
Quality Of Life ◽  
Cognitive Impairment ◽  
Cognitive Deficits ◽  
Cross Sectional Study ◽  
Life Questionnaire ◽  
Sectional Study ◽  
Cross Sectional ◽  
Indian Women ◽  
Quality Of Life Questionnaire

Stroke is main cause of death and disability which mainly affect higher function like cognitive impairment which affects the quality of life. The MoCA used to assessment of cognitive impairment and stroke specific quality of life for assessment of quality of life. The aim was to assess the effect of Cognitive Impairment on quality of life in Rural Indian women after stroke. The cognitive impairment was measured with the use of the MoCA and Quality of Life was measured by SS-Quality of Life questionnaire. Female stroke patient with age in between 41-70 year who was diagnosed by the physician is included in the study. Result of this study indicated that the cognitive functions ans quality of life significantly affected in rural females following stroke. (0.571; p=0.0001).the finding is the cognitive deficits occurred after stroke and it hamper the quality of life in majority of patient.

Abstract TP177: Stroke Camp Provides Respite for Caregivers of Stroke Survivors

Stroke ◽  
2020 ◽  
Vol 51 (Suppl_1) ◽  
Author(s):  
Maureen Mathews
Keyword(s):  
Quality Of Life ◽  
Personal Growth ◽  
Average Score ◽  
Stroke Survivors ◽  
Life Questionnaire ◽  
Convenience Sample ◽  
Education Access ◽  
Caucasian Americans ◽  
Care Givers

Background: Stroke is the leading cause of disability in the US. Approximately one in four patients with stroke is disabled. Providing daily care to stroke survivors long term is very burdensome to the family. The wellbeing and respite of the care givers (CG) has not been studied well in the past. In this study, we focused on quality of life (QOL) of the CGs of stroke survivors. The Retreat and Refresh Stroke Camp (RRSC), initiated in 2004, offers respite, opportunities to develop new relationships, and provides education/access to resources to CG. Methods: QOL of a convenience sample of stroke CG attending the Retreat and Refresh Stroke Camp (RRSC) in 2016 -2018 was assessed using the Adult Carer Quality of Life Questionnaire (ACQOLQ). The ACQOLQ addresses 8 subcategories of QOL: support for caring, caring choice, caring stress, financial matters, personal growth, sense of value, ability to care, and care satisfaction. A high (11+) subcategory score indicates high quality of life in that category and a low score (0-5) indicates a low quality of life and potential difficulties. Emails were sent to all CG with a link to the survey on Survey Monkey. Results were analyzed using descriptive statistics and Student t test was used to compare QOL between females and males. Results: A total of 149 CG were assessed including 123 (83%) females and 26 (17%) males. The majority (91%) were Caucasian Americans. The average age was 61.8 (SD=11.7) years old with a range of 27 to 86 years. More than half (56.1%) worked over 40 hours per week. The average of caring time was 7 (SD=6.6) years. The average total score of ASQOLQ was 62.4 (SD=8.9) and the average score in eight subcategories varied between 6.4 and 10.1, indicating a moderate quality of life. Females had a higher score of caring stress than males (6.7 vs 5.2, p=0.027), but no difference was found in other subcategories. Conclusion: Women are the primary caregivers for stroke survivors and bear a significantly higher burden of caring stress. Society should focus more attention to provision of resources to assist in relieving this burden. A camp opportunity for supporting caregivers and survivors may help in providing respite to these family members

The influence of cognitive impairment on health-related quality of life in neurological disease

2010 ◽  
Vol 22 (1) ◽  
pp. 2-13 ◽  
Author(s):  
Alex J. Mitchell ◽  
Steven Kemp ◽  
Julián Benito-León ◽  
Markus Reuber
Keyword(s):  
Quality Of Life ◽  
Multiple Sclerosis ◽  
Cognitive Impairment ◽  
Cognitive Deficits ◽  
Neurological Disorders ◽  
Neurological Disease ◽  
Health Related Quality ◽  
Related Quality ◽  
Health Related

Mitchell AJ, Kemp S, Benito-León J, Reuber M. The influence of cognitive impairment on health-related quality of life in neurological disease.Background:Cognitive impairment is the most consistent neurological complication of acquired and degenerative brain disorders. Historically, most focus was on dementia but now has been broadened to include the important construct of mild cognitive impairment.Methods:Systematic search and review of articles linked quality of life (QoL) and cognitive complications of neurological disorders. We excluded QoL in dementia.Results:Our search identified 249 publications. Most research examined patients with brain tumours, stroke, epilepsy, head injury, Huntington's disease, motor neuron disease, multiple sclerosis and Parkinson's disease. Results suggested that the majority of patients with epilepsy, motor neuron disease, multiple sclerosis, Parkinson's disease, stroke and head injury have subtle cognitive deficits early in their disease course. These cognitive complaints are often overlooked by clinicians. In many cases, the cognitive impairment is progressive but it can also be relapsing-remitting and in some cases reversible. Despite the importance of severe cognitive impairment in the form of dementia, there is now increasing recognition of a broad spectrum of impairment, including those with subclinical or mild cognitive impairment. Even mild cognitive difficulties can have functional and psychiatric consequences–especially when they are persistent and untreated. Specific cognitive deficits such an inattention, dysexecutive function and processing speed may affect a number of quality of life (QoL) domains. For example, cognitive impairment influences return to work, interpersonal relationships and leisure activities. In addition, fear of future cognitive decline may also impact upon QoL.Conclusions:We recommend further development of simple tools to screen for cognitive impairments in each neurological condition. We also recommend that a thorough cognitive assessment should be a part of routine clinical practice in those caring for individuals with neurological disorders.

Hypofractionated radiotherapy for complicated bone metastases in patients with poor performance status: a phase II international trial

2018 ◽  
Vol 105 (2) ◽  
pp. 181-187 ◽  
Author(s):  
Mauricio F. Silva ◽  
Gustavo N. Marta ◽  
Felipe P.C. Lisboa ◽  
Guilherme Watte ◽  
Fabio Trippa ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Bone Metastases ◽  
Phase Ii ◽  
Weight Bearing ◽  
Performance Status ◽  
Poor Performance ◽  
Hypofractionated Radiotherapy ◽  
Poor Performance Status ◽  
Life Questionnaire

Purpose: To evaluate the efficacy and safety of hypofractionated radiotherapy (16 Gy in 2 fractions, 1 week apart) in patients with complicated bone metastases and poor performance status. Methods: A prospective single-arm phase II clinical trial was conducted from July 2014 to May 2016. The primary endpoint was pain response as defined in the International Consensus on Palliative Radiotherapy Endpoints. Secondary endpoints included quality of life as measured by quality of life questionnaire (QLQ) PAL-15 and QLQ-BM22 European Organisation for Research and Treatment of Cancer guidelines, pain flare, adverse events, re-irradiation, and skeletal complications. Results: Fifty patients were enrolled. There were 23 men with a median age of 58 years (range 26-86). Of the 50 patients, 38 had an extraosseous soft tissue component, 18 needed postsurgical radiation, 3 had neuropathic pain, and 3 had an impending fracture in a weight-bearing bone. At 2 months, 33 patients were alive (66%). Four (12.5%) had a complete response and 12 (37.5%) had a partial response. A statistically significant improvement was seen in the functional interference (p = 0.01) and psychosocial aspects (p = 0.03) of the BM22. No patient had spinal cord compression. One patient required surgery for pathologic fracture, and another re-irradiation. Conclusions: Hypofractionated radiotherapy (16 Gy in 2 fractions of 8 Gy 1 week apart) achieved satisfactory pain relief and safety results in patients with complicated bone metastases and poor performance status.

Quality of Life in Dementia Sufferers: The Role of Diet and Exercise

2018 ◽  
Vol 15 (5) ◽  
pp. 400-407 ◽  
Author(s):  
Pasquale Ricci ◽  
Francesco Massoni ◽  
Lidia Ricci ◽  
Emanuela Onofri ◽  
Giuseppe Donato ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Cognitive Impairment ◽  
Mini Mental State Examination ◽  
Objective Evaluation ◽  
Anthropometric Data ◽  
People With Dementia ◽  
Diet And Exercise ◽  
State Examination

Background: Among the myriad of factors modulating quality of life assessments estimated in patients presenting a variety of cognitive impairments, the distinctive and critical influence of diet and exercise cannot be overestimated. Objective: The objective of this study was to review the evidence to confirm the association between these health-endowering agents and cognitive performance in People With Dementia as well as providing a correlation between Mini Mental State Examination scores and available anthropometric data. Methods: The authors tested the hypothesized correlation on a sample of subjects with instrumentally confirmed cognitive impairment using parameters as Body Mass Index and calf circumference. Results: The results confirm the hypothesis and suggesting the possible use of anthropometric data in the process of objective evaluation of the patient with cognitive impairment that could also be used for forensic medicine.

scholarly journals An Exploration of Quality of Life Contributors for Stroke Survivors: Potential Implications for Service Delivery Within the Community Rehabilitation Context

2020 ◽  
Author(s):  
Gaylea Fritsch ◽  
Sarah Patterson ◽  
Anita Blight ◽  
Renaye Daniells
Keyword(s):  
Quality Of Life ◽  
Service Delivery ◽  
World Health ◽  
Rehabilitation Service ◽  
Personality Factors ◽  
Stroke Survivors ◽  
Life Questionnaire ◽  
Personal Factors ◽  
Community Rehabilitation

Purpose: Community rehabilitation services typically assist stroke survivors with function, participation, and quality of life. Many factors have been found to influence the overall quality of life including self-identity, control, social supports, personality, and participation in valued activities. This review explored the possible contributing quality of life factors for stroke survivors within a community rehabilitation context to assist with further development of service delivery within this clinical area. Method: A purposive sample of clients with stroke (n=20) was selected based on their overall quality of life change during their rehabilitation program as measured on the World Health Organisation Quality of Life Questionnaire. Clients with the largest positive and negative quality of life changes were included. A clinical record review of client medical records was undertaken of these stroke survivors to identify and describe common themes that may be related to quality of life. Results: Five general themes emerged relating to possible contributing factors to quality of life for clients participating in this community stroke rehabilitation setting including transiting between hospital and community, flexibility of service delivery model, strength of family and household relationships, acceptance and expectation of both service delivery and functional levels, and ongoing co-morbid medical issues. Conclusions: This review suggests that community rehabilitation service models of care should be flexible and tailored to client needs and goals to enable a true “client-centered” approach. Social and behavioural paradigms should be incorporated within the community rehabilitation settings. Services should focus on personal factors such as the stroke survivor's adjustment to their situation, personality factors, and outcome expectations. Consideration also needs to be given to the overall continuum of care of health care services.

The Impact of Cognitive Impairment on Poststroke Outcomes: A 5-Year Follow-Up

2019 ◽  
Vol 32 (5) ◽  
pp. 275-281 ◽  
Author(s):  
Daniela Rohde ◽  
Eva Gaynor ◽  
Margaret Large ◽  
Lisa Mellon ◽  
Patricia Hall ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Cognitive Impairment ◽  
Depressive Symptoms ◽  
Informal Care ◽  
Care Quality ◽  
Stroke Survivors ◽  
Linear Regression Models ◽  
The Impact

Aim: To explore the impact of cognitive impairment poststroke on outcomes at 5 years. Methods: Five-year follow-up of the Action on Secondary Prevention Interventions and Rehabilitation in Stroke (ASPIRE-S) prospective cohort. Two hundred twenty-six ischemic stroke survivors completed Montreal Cognitive Assessments at 6 months poststroke. Outcomes at 5 years included independence in activities of daily living, receipt of informal care, quality of life, and depressive symptoms. Data were analyzed using logistic and linear regression models. Adjusted odds ratios (ORs; 95% confidence interval [CI]) and β coefficients (95% CI) are reported. Results: One hundred one stroke survivors were followed up at 5 years. Cognitive impairment at 6 months was independently associated with worse quality of life (B [95% CI]: −0.595 [−0.943 to −0.248]), lower levels of independence (B [95% CI]: −3.605 [−5.705 to −1.505]), increased likelihood of receiving informal care (OR [95% CI]: 6.41 [1.50-27.32]), and increased likelihood of depressive symptoms (OR [95% CI]: 4.60 [1.22-17.40]). Conclusion: Cognitive impairment poststroke is associated with a range of worse outcomes. More effective interventions are needed to improve outcomes for this vulnerable group of patients.

Pharmacologic manipulation of complement receptor 3 prevents dendritic spine loss and cognitive impairment after acute cranial radiation

2020 ◽  
Author(s):  
Joshua J. Hinkle ◽  
John A. Olschowka ◽  
Jacqueline P. Williams ◽  
M. Kerry O’Banion
Keyword(s):  
Quality Of Life ◽  
Cognitive Impairment ◽  
Cognitive Deficits ◽  
Dendritic Spine ◽  
Cranial Irradiation ◽  
Complement Receptor ◽  
Spine Density ◽  
Male Mice ◽  
Complement Receptor 3

AbstractCranial irradiation induces healthy tissue damage that can lead to neurocognitive complications and negatively impact patient quality of life. One type of damage associated with cognitive impairment is loss of neuronal spine density. Based on developmental and disease studies implicating microglia and complement in dendritic spine loss, we hypothesized that irradiation-mediated spine loss is microglial complement receptor 3 (CR3)-dependent, and associated with late-delayed cognitive deficits. Utilizing a model of cranial irradiation (acute, 10 Gy gamma) in C57BL/6 mice we found that male mice demonstrate irradiation-mediated spine loss and cognitive deficits whereas female mice and CR3 knockout mice do not. Moreover, pharmacological blockade of CR3 with leukadherin-1 (LA1) prevented these changes in irradiated male mice. Interestingly, CR3 KO mice showed reduced behavioral task performance suggesting that CR3 is important for normal learning and memory. Improving our understanding of irradiation-mediated mechanisms and sexual dimorphic responses is essential for the identification of novel therapeutics to reduce irradiation-induced cognitive decline and improve patient quality of life.

scholarly journals Reliability and Validity of the Lithuanian Version of CASP-19: A Quality of Life Questionnaire for the Elderly

Medicina ◽  
2018 ◽  
Vol 54 (6) ◽  
pp. 103 ◽  
Author(s):  
Andrejus Černovas ◽  
Vidmantas Alekna ◽  
Marija Tamulaitienė ◽  
Rimantas Stukas
Keyword(s):  
Quality Of Life ◽  
Psychometric Properties ◽  
Reliability And Validity ◽  
The Elderly ◽  
Cross Sectional Study ◽  
Life Questionnaire ◽  
Cross Sectional ◽  
High Internal Consistency ◽  
State Examination

Introduction: Ageing is associated with several physical, psychological, and behavioral changes. These changes are closely related with general health problems and quality of life in old age. The CASP-19 multidimensional instrument was specially designed to measure quality of life in the elderly. The different language versions of this scale have been used in more than 20 countries. However, Lithuanian translation was not available. The objective of our study was to test psychometric properties of the Lithuanian version of the CASP-19 questionnaire. Materials and methods: A cross-sectional study was performed with ambulatory men and women aged 60 and older, living in a community in Vilnius, Lithuania. Exclusion criteria were current acute illness, malignant tumor, and Mini-Mental State Examination (MMSE) score < 25 points. Psychometric properties of CASP-19 were tested using reliability and validity methods. Results: The study sample consisted of 132 participants, 28 (21.8%) of them were men and 103 (78.2%) women. Analysis of psychometric properties of the Lithuanian version of CASP-19 showed high internal consistency (Cronbach’s alpha 0.85), good agreement between test-retest measures with an ICC of 0.82 (95% CI 0.79–0.85) and good convergent and divergent construct validity. Conclusions: The psychometric properties indicated that the Lithuanian version of CASP-19 was reliable and valid. As such, it might be used to evaluate quality of life in elderly people.

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