scholarly journals Clinical Study of the Change of pH Level in the Supragingival Plaque in Children after Taking Homeopathic Remedies

2021 ◽  
Vol 48 (1) ◽  
pp. 17-24
Author(s):  
A. Pomakova ◽  
N. Gateva ◽  
K. Hristov

Abstract Objective: There are numerous publications on the parameters of conventional medications, which contribute to their cariogenic and erosive potential. Little is known about the homeopathic remedies (HR) and the changes in the oral cavity they lead to, especially during childhood. Material and methods: The study involved 25 children (5-9 years of age). It monitored the change in plaque pH level after intake of three frequently used homeopathic remedies in five consecutive weeks. The pH level values were measured after the administration of the remedies, without HR intake, and after rinsing with 10% sucrose solution. Five groups were formed – two controls and three groups with results from the tested HR. Results: A drop in the plaque pH level was observed after intake of all HR and in all tested individuals. The biggest decrease was observed at the 15th minute for all HR. At the 30th minute the greatest decrease was observed with the second remedy, and at 60th minute – with the first and second. Conclusions: A dramatic decrease in the plaque pH level was observed after intake of each studied remedy. In many cases the drop was below the critical value of pH = 5.5. The low plaque pH values were maintained even at the 60th minute after the start of the study.

2018 ◽  
Vol 12 (02) ◽  
pp. 199-203 ◽  
Author(s):  
Pinar Gul ◽  
Nilgun Akgul ◽  
Nilgun Seven

ABSTRACT Objective: This study aimed to examine the effects of these foods on plaque pH and the potential development of tooth decay. Materials and Methods: Plaque pH was measured using the sampling method before and after 1, 5, 10, 20, 30, 45, and 60 min following consumption of these foods individually and after rinsing with a 10% sucrose solution. Statistical analysis was performed using one-way ANOVA and Tukey honestly significant difference post hoc tests (α = 0.05). Results: Although there were statistically significant differences in all test groups except the BT (P = 0.620) and sucrose + XCG (P = 0.550) groups in time, none of the participants chosen for this study were having a plaque pH value anywhere close to the critical value (pH = 5.5). Conclusion: WC, BT, and XCG are advisable as anticariogenic foods because pH values are not below critical value.


2017 ◽  
Vol 41 (1) ◽  
pp. 22-26 ◽  
Author(s):  
Mazhari Fatemeh ◽  
Sharifi Marjan ◽  
Noorollahian Homa ◽  
Sharifi Mahsa

Objectives: There is some evidence that water rinsing immediately after topical fluoride therapy has the potential to reduce the effectiveness of fluoride. The aim was to determine if covering fluoridated teeth with a layer of mousse containing CPP-ACP could prevent the adverse effect of rinsing on fluoride and consequently its buffering effect on dental plaque pH during cariogenic challenge. Study design: This randomized, controlled, crossover, in situ study was conducted on 25 participants. The participants were subjected to acidulated phosphate fluoride (APF) application followed by five treatment protocols: (1) water rinsing after 30 minutes (APF-30) or (2) immediate water rinsing (APF-0); (3) using CPP-ACP immediately before water rinsing (F-CPP-ACP); and two control groups: (4) no fluoride therapy (No-F) and (5) using CPP-ACP and immediate water rinsing (CPP-ACP-0). After 48 hours, teeth were rinsed with 10% sucrose solution and plaque pH was measured before and after 5, 10, 15, 20 and 30 minutes. Results: The least pH changes, the lowest pH drop, and the quickest pH recovery were found in the APF-30 and F-CPP-ACP groups. APF-0 ranked in the middle and the highest values were in the control groups. Conclusions: The results show that in the case using CPP-ACP on fluoridated teeth, water rinsing immediately after topical fluoride therapy did not seem to influence the inhibitory effect of fluoride on plaque acidity.


2019 ◽  
Vol 98 (11) ◽  
pp. 1245-1252 ◽  
Author(s):  
M.M. Nascimento ◽  
A.J. Alvarez ◽  
X. Huang ◽  
C. Browngardt ◽  
R. Jenkins ◽  
...  

Caries lesions develop when acid production from bacterial metabolism of dietary carbohydrates outweighs the various mechanisms that promote pH homeostasis, including bacterial alkali production. Therapies that provide arginine as a substrate for alkali production in supragingival oral biofilms have strong anticaries potential. The objective of this study was to investigate the metabolic profile of site-specific supragingival plaque in response to the use of arginine (Arg: 1.5% arginine, fluoride-free) or fluoride (F: 1,100 ppm F/NaF) toothpastes. Eighty-three adults of different caries status were recruited and assigned to treatment with Arg or F for 12 wk. Caries lesions were diagnosed using International Caries Detection and Assessment System II, and plaque samples were collected from caries-free and carious tooth surfaces. Taxonomic profiles were obtained by HOMINGS (Human Oral Microbe Identification using Next Generation Sequencing), and plaque metabolism was assessed by the levels of arginine catabolism via the arginine deiminase pathway (ADS), acidogenicity, and global metabolomics. Principal component analysis (PCA), partial least squares–discriminant analysis, analysis of variance, and random forest tests were used to distinguish metabolic profiles. Of the 509 active lesions diagnosed at baseline, 70 (14%) were inactive after 12 wk. Generalized linear model showed that enamel lesions were significantly more likely to become inactive compared to dentin lesions ( P < 0.0001), but no difference was found when treatment with Arg was compared to F ( P = 0.46). Arg significantly increased plaque ADS activity ( P = 0.031) and plaque pH values after incubation with glucose ( P = 0.001). F reduced plaque lactate production from endogenous sources ( P = 0.02). PCA revealed differences between the metabolic profiles of plaque treated with Arg or F. Arg significantly affected the concentrations of 16 metabolites, including phenethylamine, agmatine, and glucosamine-6-phosphate ( P < 0.05), while F affected the concentrations of 9 metabolites, including phenethylamine, N-methyl-glutamate, and agmatine ( P < 0.05). The anticaries mechanisms of action of arginine and fluoride are distinct. Arginine metabolism promotes biofilm pH homeostasis, whereas fluoride is thought to enhance resistance of tooth minerals to low pH and reduce acid production by supragingival oral biofilms.


2010 ◽  
Vol 04 (02) ◽  
pp. 156-159 ◽  
Author(s):  
Alessandro Leite Cavalcanti ◽  
Ianny Alves Ramos ◽  
Rafaela Bastos Leite ◽  
Mariana da Costa Oliveira ◽  
Karynna de Melo Menezes ◽  
...  

Objectives: To evaluate in vitro the endogenous pH, titratable acidity and total soluble solid content (TSSC) of mouthwashes available in the Brazilian market.Methods: The study sample was composed of 10 commercial brands of mouthwashes based on different active ingredients: Cepacol®, Clinerize®, Equate®, Listerine Cool Citrus®, Oral-B®, Periogard ®, Peroxyl®, Plax Overnight®, Prevident 220® and Sanifill®. The experiments were performed in triplicate. The endogenous pH was evaluated by potentiometry, titratable acidity was evaluated by the addition of 0.1N KOH increments to the mouthwashes, and TSSC readings were performed by Brix refractometry using the Abbé refractometer.Results: pH values ranged from 3.56 (Peroxyl®) to 7.43 (Cepacol®) and three mouthwashes presented pHs below 5.5. The titratable acidity values ranged from 0.007 (Periograd®) to 0.530 (Prevident ®). Oral B® and Clinerize® presented the lowest (4.7%) and the highest (23.70%) TSSC, respectively.Conclusions: Some of the mouthwashes evaluated in this study presented low endogenous pH, even below the critical value for enamel dissolution (pH<5.5), high titratable acidity and high TSSC, and may be potentially erosive to the dental tissues if not properly used. (Eur J Dent 2010;4:156-159)


2018 ◽  
Vol 64 (4) ◽  
Author(s):  
Przemysław Reszka ◽  
Łukasz Kucharski ◽  
Adam Klimowicz ◽  
Mariusz Lipski

ABSTRACTIntroduction: The aim of this in vitro study was to assess the pH values of selected calcium-silicate root canal sealers in comparison with AH Plus resin-based root canal sealer.Materials and methods: Six root canal sealers were included in this study: BioRoot RCS (Septodont, France), GuttaFlow bioseal (Coltėne/Whaledent, Switzerland), MTA Fillapex (Angelus, Brazil), Total Fill BC Sealer (FKG, Switzerland), Well-Root ST (Vericom, Korea) and AH Plus (Dentsply, DeTrey, Germany). Materials samples (n = 6) were placed in dishes and immersed in 10 mL of distilled water (pH = 6.8). After 1, 3, 24, 48, 72, 168, 336 and 504 hrs, water pH was determined with a pH meter calibrated with a solution of known pH. Data were statistically analyzed using Student-t test (p < 0.05).Results: There were differences in the water pH between the materials tested. The highest water pHs were exhibited by Total Fill BC Sealer, Well-Root ST and BioRoot RCS (pH ~12), followed by GuttaFlow bioseal (pH ~10.5) and MTA Fillapex (pH ~9). The lowest pH was shown by AH Plus (pH ~8).Conclusions: All calcium-silicate root canal sealers studied are able to elevate the pH level, which could have biological and antimicrobial effects. The AH Plus root canal sealer has poor alkalizing properties.


2020 ◽  
Vol 54 (4) ◽  
pp. 358-368
Author(s):  
Thamires Priscila Cavazana ◽  
Juliano Pelim Pessan ◽  
Thayse Yumi Hosida ◽  
Caio Sampaio ◽  
Viviane de Oliveira Zequini Amarante ◽  
...  

The aim of the present study was to evaluate the influence of sodium trimetaphosphate (TMP), associated or not with fluoride (F), on the concentrations of F, calcium (Ca), and phosphorus (P) and on the pH of mixed biofilms of <i>Streptococcus mutans</i> and <i>Candida albicans</i>, before and after exposure to sucrose. The biofilms received three treatments (72, 78, and 96 h after the beginning of their formation), at three TMP concentrations (0.25, 0.5, or 1%), with or without F at 500 ppm. Solutions containing 500 and 1,100 ppm F as well as artificial saliva were also tested as controls. Biofilm pH was measured and the concentrations of F, Ca, and P were determined (solid and fluid phases). In a parallel experiment, after the third treatment (96 h), the biofilms were exposed to a 20% sucrose solution to simulate a cariogenic challenge and the pH of the medium, F, Ca, P, and TMP were determined. The data were submitted by two-way ANOVA, followed by Fisher’s least significant difference test (<i>p</i> &#x3c; 0.05). Treatment with TMP and 500 ppm F led to higher F concentration in the biofilm fluid. Although TMP did not affect Ca concentrations, biofilms treated with TMP alone presented higher P concentrations. Treatment with 1% TMP and F led to the highest pH values of the biofilm, both before and after the cariogenic challenge. It was concluded that TMP increases F and P in the biofilm and that its presence promotes an increase in the pH of the medium, even after the cariogenic challenge.


2020 ◽  
Vol 33 (3) ◽  
pp. 174-180
Author(s):  
Gerson Langa ◽  
Francisco Gomes Muniz ◽  
Harry Rivera Oballe ◽  
Juliano Cavagni ◽  
Stephanie Anagnostopoulos Friedrich ◽  
...  

The aim of the present examiner-blind randomized controlled clinical study was to compare the efficacy two soft-bristle toothbrushes in terms of plaque removal. Seventy volunteers were randomly allocated to Group A (tapered-tip toothbrush) or Group B (end-rounded toothbrush). At baseline appointment (Day 0), volunteers underwent plaque examination using the Improved Plaque Identification Index. Under supervision, they brushed their teeth for 1 minute with their assigned toothbrushes and the plaque examination was repeated. Volunteers continued the oral hygiene regimen (assigned toothbrush and a regular dentifrice provided by the researchers) for 7 days. The experimental procedures of Day 0 were then repeated. Separate statistical analyses were performed for mean percent reduction of plaque in the whole-mouth, interproximal and gumline scores at both times, using Mann-Whitney test, p0.05). In conclusion, on Day 0, Group A presented higher efficacy in supragingival plaque removal than Group B, as reflected by whole-mouth, gumline and interproximal plaque scores.


1994 ◽  
Vol 8 (2) ◽  
pp. 215-220 ◽  
Author(s):  
W.H. Bowen

For many decades, sugars have been the dietary constituents receiving the most attention in relation to their effects on dental caries. Frequently, however, there is little relationship between the amount of sugar in a food and its ability to induce caries. Therefore, it is clear that constituents in the diet can influence the ability of plaque to lower the pH of sugar solutions. For instance, replacing sugar in foods with xylitol, sorbitol, saccharin, oraspartamemay lead to areduction in the incidence of dental caries. All these sugar substitutes are non-cariogenic, and some may possess cariostatic properties. The presence of arginine-rich proteins in the diet may provide a ready source of this amino acid, which is the substrate for the arginine deiminase pathway which can result in a rapid elevation of plaque pH values. Proline can act as an acceptor for protons from lactate in the Stickland reaction. This is a major but much-neglected metabolic pathway in dental plaque. The presence of fat in experimental diets has been shown to affect their cariogenicity. The effects have been ascribed to enhanced clearance of sugars from the mouth. It is also conceivable that several fatty acids express a potent antibacterial effect. The presence of calcium and phosphorus has been shown to influence the cariogenicity of foods; the effect, however, is restricted to the food containing the minerals. Evidence suggests that pyridoxine (vitamin B6) may exert a cariostatic effect by enhancing decarboxylation activity in dental plaque. It is clear that sugar alone is not the sole determinant of whether food is cariogenic. Furthermore, myriad substances may hinder or enhance the caries-promoting properties of sugars in the diet.


Author(s):  
Tatiana Akaeva ◽  
Karen Mkhitaryan ◽  
Ole Vasilkovskaya ◽  
Mikhail Gotovskiy

Background One of the most important tasks in anti-age therapy and rejuvenation practice is the regeneration of various tissues, organs and body systems [1,2]. In this study, we evaluated the effectiveness of therapy with the new class of homeopathic and informational preparations “Triton Regeneration” and “Triton Metamorphosis” [3]. The preparations were used both in homeopathic dilutions, and in the form of control signals of the Triton (CSTrit). Aims To apply in practice the homeopathic preparations “Triton regeneration” and “Triton metamorphosis” in the form of homeopathic dilutions and control signals, in order to regenerate the organs of the tissues and systems of the patient and evaluate the results obtained. Methodology A clinical study was conducted on a group of 33-st people aged between 7-75 years of both sexes who received injuries to the skin, connective tissue and / or musculoskeletal system. The study was conducted by a multicenter method in the cities: Moscow (Russia), Gabrovo (Bulgaria), Arad (Romania). All patients gave informed consent for treatment. To write a CS and their applications, for diagnostics and therapy, and the fabrication for the necessary preparations and marker CMH, the integrated system for electropuncture diagnostic « IMEDIS-EXPERT» was used. For the diagnosis method was used vegetative resonance test (VRT). Cultures of the biological material of the triton were used to obtain control signals triton (CSTrit) therapy. The method of bioresonance therapy (BRT) was used to adapt and administer the condition of the patient. Adaptation of the preparations to the patient's body was carried out by electron potentiation of the initial CSTrit until the VRT condition was met: ?MH ? + Pot ? (CSTrit) ? The marker ?MH-individual constitutional marker represents the sum of signals from the nodal and terminal BAT (biologically active points) located on the main chirohlyphic palm lines of the patient. Patients used the homeopathic remedies of triton and / or adapted CSTrit in individual dosage during the individual course of therapy. At subsequent receptions, a second VRT was re-examined and the degree of recovery of defects in the skin, connective tissue and / or the musculoskeletal system was assessed. Results This clinical study showed a high efficacy of homeopathic and informational preparations of CSTrit in patients who received injuries of the skin, connective tissue and / or musculoskeletal system. A pronounced positive effect was obtained in all cases of treatment of CSTrit: objective processes of regeneration of the connective tissue system of the patients were noted, in particular, restoration of its skin. In the case of treatment therapy for injuries of the musculoskeletal system, marked regeneration processes in the bone and tendon tissues were observed, confirmed by R-studies. Conclusion 1. Homeopathic remedies “Triton regeneration” and “Triton metamorphosis”, as well as the control signals of the Triton (CSTrit), made using the apparatus "IMEDIS-EXPERT", are effective signals of the regeneration of body tissues, as in the case of treatment of skin and connective tissue damage, and in case of damage to bone tissue and tendons. 2. Therapy of patients with CSTrit, potentiated by the ?MH marker, is comparable in effectiveness and end results with mono- and complex homeopathic therapy and in some cases surpasses it. 3. A new class of the preparations - gives a positive result in 96% of cases. Similar results are unattainable with ordinary homeopathy.


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