scholarly journals Comparative Analysis Between the Basdai and Mini-Basdai Indices in Patients with Ankylosing Spondylitis

2018 ◽  
Vol 15 (5) ◽  
pp. 7-14
Author(s):  
Sandra Burtica ◽  
Adriana Gurghean ◽  
Ion Bruckner
Keyword(s):  
New York ◽  
Ankylosing Spondylitis ◽  
Biological Therapy ◽  
Cross Sectional Study ◽  
Individual Characteristics ◽  
Cross Sectional ◽  
Duration Of Disease ◽  
The Mean ◽  
The Individual ◽  
Spinal Flexion

AbstractObjectives. The aim of this paper is to compare the degree of accuracy between the BASDAI and mini-BASDAI indices in assessing the activity of ankylosing spondylitis (AS), especially in patients without peripheral manifestations.Materials and method. Our cross-sectional study consisted of a group of 124 patients with AS, according to the modified New York criteria. All patients offered their informed consent. All the individual characteristics of the patients were documented, both demographic and disease-related. The activity of the disease was measured using the BASDAI questionnaire, from which we calculated the mini-BASDAI by eliminating the questions about peripheral arthritis and entesitis. The functional impairment of mobility in the spine and sacro-iliac joints was measured by the Schober index, lateral spinal flexion, occiput-wall, menton-sternum and finger-ground index.Results. The mean age of the patients was 43.43 +/− 13.27 years, mean height 174.3 +/− 8.46 cm, weight 78.23 +/− 14.19 kg, duration of disease in years 15.06 +/− 9.19 and number of years from initiation of biological therapy 6.42 +/− 3.08. The BASDAI score was 1.26 +/− 1.93, while the mini-BASDAI score was 1.51 +/− 2.08. In the group of patients without peripheral manifestations, both BASDAI and mini-BASDAI correlated significantly with the occiput-wall index, besides ESR, CRP, ASDAS-CRP and the Schober index.Conclusion. Mini-BASDAI is not superior to BASDAI in evaluating patients with ankylosing spondylitis without peripheral manifestations, but it has shown a better correlation in addition to BASDAI with the indices of flexion of the cervico-dorsal spine.

scholarly journals AB0703 WHICH OF THE ASDAS OR BASDAI CORRELATES BETTER WITH PHYSICIAN GLOBAL ASSESSMENT?

2020 ◽  
Vol 79 (Suppl 1) ◽  
pp. 1647.4-1647
Author(s):  
K. Maatallah ◽  
W. Triki ◽  
H. Ferjani ◽  
D. Kaffel ◽  
W. Hamdi
Keyword(s):  
New York ◽  
Ankylosing Spondylitis ◽  
Disease Activity ◽  
Global Assessment ◽  
Cross Sectional Study ◽  
Face Validity ◽  
Physician Global Assessment ◽  
Cross Sectional ◽  
Asas Criteria ◽  
The Mean

Background:Ankylosing Spondylitis Disease Activity score (ASDAS) was developed because of the limitations of Bath Ankylosing Spondylitis Disease Index (BASDAI) of being totally patient-derived with limited face and construct validity. ASDAS includes inflammatory markers that were aimed to increase its face validity by representing a different ‘objective’ domain of disease activity that was not included in BASDAI.Objectives:The aim of our study was to compare correlation of ASDAS and BASDAI with physician global assessment (PhGA) in order to know which is more reliable.Methods:Cross-sectional study including patients with SpA according to the ASAS criteria of 2009 and/or New York modified criteria. The erythrocyte sedimentation rate (ESR) and the C-reactive protein (crp) were measured. The disease activity was assessed by BASDAI and ASDAS. Physician global assessment (PhGA) was rated by 0–100 numeric score. We correlated disease activity indices with physician global assessment by Pearson coefficient.Results:A total of 110 patients (68 men and 42 women) with a mean age of 43.18 ±12.34 [19-79] years was collected. The mean disease duration was 5.99±2.31 [1-10] years. The mean ESR and CRP were respectively 28.41±21.51 [2-110] and 15.56 ±23.84 [0-153] mg/l. ESR was correlated with PhGA (p=0.06, r=0.300), however CRP was not correlated with PhGA (p=0.134, r=0.165). The mean ASDAS-ESR and ASDAS-CRP were respectively 2.93±1.05 [0.83-5.65] and 2.81±0.97 [0.29-4.77]. The mean BASDAI was 4.42±2.23 [0-9.2]. The mean PhGA was 5.43 ±2.31 [1-10]. The BASDAI correlated with PhGA (p=0.007, r=0.307). In addition, ASDAS-ESR and ASDAS-CRP correlated with PhGA (p=0.001, r=0.372, p=0.001, r=0.391) respectively.Conclusion:In conclusion both BASDAI and ASDAS are equal, with a superiority nonetheless for the ASDAS since it correlated stronger with PhGA.Acknowledgments:NoneDisclosure of Interests:None declared

Satisfaction and Adherence to Biological Treatment in Patients with Rheumatic Diseases

2021 ◽  
Vol 18 ◽  
Author(s):  
Marwa Hammad ◽  
Huny Bakry
Keyword(s):  
Rheumatic Diseases ◽  
Biological Treatment ◽  
Formal Education ◽  
Biological Therapy ◽  
Cross Sectional Study ◽  
P Value ◽  
Inflammatory Rheumatic Diseases ◽  
Cross Sectional ◽  
New Era ◽  
The Mean

Background: Autoimmune inflammatory rheumatic diseases have long been treated by conventional disease-modifying anti-rheumatic drugs. Biological therapy is a new era in the treatment of rheumatic diseases, but satisfaction and adherence to it is still not well tested. Aim: To assess the satisfaction and adherence to biological treatment among patients with autoimmune inflammatory rheumatic diseases. Methods: A cross sectional study was conducted among 56 patients suffering from inflammatory rheumatic diseases using Morisky 8 questionnaire and Treatment Satisfaction Questionnaire for Medication (TSQM) over a period of one month Results: About 76.8% of the patients had medium adherence and the underlying cause of missing doses was the unavailability of the drugs. The mean satisfaction with biological treatment was 62.7±6.9. Patients who did not receive formal education had significantly higher satisfaction with the biological treatment than others 64.94±5.01 at a P value 0.04 (<0.05). Conclusion: Patients with inflammatory rheumatic diseases in our study showed medium adherence and satisfaction. Authorities in the medical field are providing great help to these patients in need of biological therapy, but ensuring the availability of all doses of the biological treatment regimen is still necessary. Patient, family and nurse education programs are also necessary to maximize adherence and satisfaction.

scholarly journals Efectos ergonómicos inmediatos de un apoyo isquiático en la sedestación. Herramienta preventiva para la información en salud = Immediate ergonomic effects of an ischial support in the sitting position. Preventive tool for health information

2017 ◽  
Vol 8 (2) ◽  
pp. 228
Author(s):  
Luis Ceballos-Laita ◽  
Teresa Mingo-Gómez ◽  
Sandra García-Lázaro ◽  
Sandra Jiménez-del Barrio
Keyword(s):  
Slope Angle ◽  
Cross Sectional Study ◽  
Head Position ◽  
Individual Characteristics ◽  
Sitting Position ◽  
Human Engineering ◽  
Cross Sectional ◽  
Lumbar Flexion ◽  
Upper Cervical ◽  
The Individual

Resumen: Introducción: La información sobre la correcta ergonomía se ha incrementado para disminuir la prevalencia de síntomas lumbares y/o cervicales en la población. Sin embargo, el acondicionamiento y el mobiliario de las instituciones universitarias no se adecuan a las características individuales de los sujetos, lo cual dificulta el proceso. Objetivo: analizar los cambios en la postura, al incorporar un apoyo isquiático en sujetos jóvenes. Material: Estudio transversal comparativo sobre 76 sujetos universitarios voluntarios (24 varones y 52 mujeres, edad media de 20,7; DT ± 2,64). Se registró la postura mediante fotogrametría sagital con un software 2D, en posición de sedestación y en sedestación corregida mediante la colocación de un apoyo isquiático de 5 centímetros de altura. Posteriormente se analizaron los ángulos cráneo-vertebral (CV), cervical superior (CS), cervical inferior (CI), lumbar (AL). Resultados: Se encontraron diferencias estadísticamente significativas entre la posición sedente y la sedente corregida en todos los ángulos analizados (p<0,01). Consiguiendo la disminución de la flexión lumbar y de la posición de cabeza adelantada. Conclusión: La utilización de un apoyo isquiático de 5 centímetros de altura en la posición de sedestación, disminuye la flexión lumbar y la posición de cabeza adelantada en comparación con una sedestación sin apoyo en sujetos jóvenes.Palabras clave: postura, columna, comunicación, ingeniería humana, educación para la salud.Abstract: Introduction: Information about correct ergonomics is increasing in order to avoid cervical and lumbar symptoms. However, the furniture of the colleges does not fit the individual characteristics, which make difficult the process. Objective: Analyse the posture change, when an ischial support is incorporated in young population. Methods: Cross sectional study. 76 volunteers students were included (24 men and 53 women, average age 20,7 SD ± 2,64). Posture was registered with sagittal photogrammetry and analysed by 2D software, in sitting position and corrected sitting position by 5-centimeters-isquial-support. Then, Neck Slope angle (NS), Upper Cervical angle (UP) Lower cervical angle (LC) and lumbar spine angle (LS) were analysed. Results: Statistical differences were found between the sitting position and corrected sitting position in all analysed angles (p<0,01). This means less lumbar flexion and forward head position. Conclusion: A 5-centimeter-isquial-support decrease lumbar flexion and forward head position compared to sitting position without ischial support in young adults.Keywords: posture, spine, communication, human engineering, health education.

scholarly journals Genetic homozygosity as a marker of smoking dependency

Genetika ◽  
2020 ◽  
Vol 52 (3) ◽  
pp. 1009-1019
Author(s):  
Slavko Brankovic ◽  
Dejan Nikolic ◽  
Dragoslav Marinkovic ◽  
Suzana Cvjeticanin
Keyword(s):  
Cross Sectional Study ◽  
Male Gender ◽  
Sectional Study ◽  
Cross Sectional ◽  
Male And Female ◽  
Mean Values ◽  
Individual Variations ◽  
Significant Difference ◽  
The Mean ◽  
The Individual

The aim of our study was to evaluate the morphogenetic variability as a marker of smoking dependency in adult smokers versus controls and to investigate the presence and the degree of morphogenetic variability difference between male and female smokers versus same gender controls. The cross-sectional study evaluated 241 smokers and 185 nonsmoker individuals as controls. We analyzed 17 homozygous recessive characteristics (HRC). There was a significant difference in the individual variations of 17 HRCs between the controls and smokers (??2=61.400, p<0.001; for females ??2=79.440, p<0.001; for males ??2=84.972, p<0.001). The mean values of HRCs significantly differed between smokers and controls (MV?SEM(Controls) -4.79?0.13, MV?SEM(Smokers) -5.70?0.12; p<0.001). For males, presence of 6/17 (35.29% genetic homozygosity) HRCs (OR=6.12) was to the certain degree predictor for smoking dependency. Higher degree of genetic homozygosity, changed variability and male gender, might be some among potential numerous factors that could have impact on smoking development and dependence.

scholarly journals First-Year Antibiotics Exposure in Relation to Childhood Asthma, Allergies, and Airway Illnesses

2020 ◽  
Vol 17 (16) ◽  
pp. 5700
Author(s):  
Zhijun Zou ◽  
Wei Liu ◽  
Chen Huang ◽  
Chanjuan Sun ◽  
Jialing Zhang
Keyword(s):  
Childhood Asthma ◽  
Cross Sectional Study ◽  
Individual Characteristics ◽  
First Year ◽  
Cross Sectional ◽  
Childhood Health ◽  
History Of ◽  
Household Environment ◽  
One Year ◽  
The Individual

Background: Associations of early antibiotics exposures with childhood asthma, allergies, and airway illnesses are debated. Objectives: We aimed to investigate associations of first-year antibiotics exposure with childhood asthma, allergies, and airway illnesses. Methods: A cross-sectional study was conducted among preschoolers in Shanghai, China during 2011–2012. A questionnaire regarding household environment and lifestyles and childhood health outcomes was reported by the child’s parents. Results: In total, 13,335 questionnaires (response rate: 85.3%) were analyzed and 3049 (24.1%) children had first-year antibiotics exposure. In the multivariate logistic regression analyses, first-year antibiotics exposure had significant associations with the higher odds of lifetime-ever pneumonia (adjusted OR, 95% CI: 2.15, 1.95–2.37), croup (1.46, 1.24–1.73), wheeze (1.44, 1.30–1.60), asthma (1.38, 1.19–1.61), food allergy (1.29, 1.13–1.46), and allergic rhinitis (1.23, 1.07–1.41), and as well as current (one year before the survey) common cold (≥3 times) (1.38, 1.25–1.52), dry cough (1.27, 1.13–1.42), atopic dermatitis (1.25, 1.09–1.43), wheeze (1.23, 1.10–1.38), and rhinitis symptoms (1.15, 1.04–1.26). These associations were different in children with different individual characteristics (age, sex, family history of atopy, and district) and other early exposures (breastfeeding, home decoration, pet-keeping, and environmental tobacco smoke). Conclusions: Our results indicate that first-year antibiotics exposure could be a strong risk factor for childhood pneumonia, asthma, allergies, and their related symptoms. The individual characteristics and other early exposures may modify effects of early antibiotic exposure on childhood allergies and airway illnesses.

scholarly journals Specialty Physician Designation in Referrals from a Vertically Integrated PCMH

2019 ◽  
Vol 6 ◽  
pp. 233339281985038
Author(s):  
Andrew D. Schreiner ◽  
Keri T. Holmes-Maybank ◽  
Jingwen Zhang ◽  
Justin Marsden ◽  
Patrick D. Mauldin ◽  
...  
Keyword(s):  
Medical Home ◽  
Univariate Analysis ◽  
Cross Sectional Study ◽  
Individual Characteristics ◽  
Patient Centered Medical Home ◽  
Patient Centered ◽  
Cross Sectional ◽  
Medical Specialties ◽  
The Individual

Introduction: Primary care referrals to specialty physicians once relied upon the medical skill of the specialist, the quality of past communication, and previous consultative experiences. As health systems vertically integrate, patterns of specialty physician referral designation are not known. Methods: This cross-sectional study from a patient-centered medical home (PCMH) evaluated the proportion of referrals with named specialists. All outpatient specialty referrals from the PCMH between July and December of 2014 were eligible for inclusion, and 410 patients were randomly selected for chart review. The outcome of interest was specialty physician designation. Other variables of interest included PCMH provider experience, the reason for referral, and time to specialty visit. Univariate analysis was performed with Fisher exact tests. Results: Of 410 specialty referrals, 43.7% were made to medical specialties, 41.7% to surgical specialties, and 14.6% to ancillary specialties. Resident physicians placed 224 referrals (54.6%), faculty physicians ordered 155 (37.8%), and advanced practice providers ordered 31 (7.6%). Only 11.2% of the specialty referral orders designated a specific physician. No differences appeared in the reason for referral, the referral destination, the proportion of visits scheduled and attended, or the time to schedule between those referrals with and without specialty physician designation. Faculty physicians identified a specific specialist in 21.4% of referrals compared to residents doing so in 4.9% ( P < .0001). Conclusion: Patient-centered medical home referrals named a specific specialty physician infrequently, suggesting a shift from the historical reliance on the individual characteristics of the specialist in the referral process.

scholarly journals The Role of Individual and Neighborhood Characteristics on Mental Health after a Period of Economic Crisis in the Lisbon Region (Portugal): A Multilevel Analysis

2019 ◽  
Vol 16 (15) ◽  
pp. 2647 ◽  
Author(s):  
Loureiro ◽  
Santana ◽  
Nunes ◽  
Almendra
Keyword(s):  
Mental Health ◽  
Economic Crisis ◽  
Cross Sectional Study ◽  
Poor Mental Health ◽  
Individual Characteristics ◽  
Neighborhood Environment ◽  
Neighborhood Characteristics ◽  
Multilevel Regression ◽  
Cross Sectional ◽  
The Individual

Mental health is an intrinsic dimension of health influenced by individual and contextual factors. This cross-sectional study analyzes the association between the individual, neighborhood characteristics, and one’s self-assessed mental health status in the Lisbon region after an economic crisis. Via the application of multilevel regression models, the study assesses the link between one’s neighborhood environment—deprivation, low self-assessed social capital, and low self-assessed satisfaction with the area of residence—and mental health regardless of one’s individual characteristics. Constraints related to the economic crisis play an important role in the explanation of poor mental health.

scholarly journals Correlation Between the Total Small Bowel Length and Anthropometric Measures in Living Humans: Cross-Sectional Study

2019 ◽  
Vol 30 (2) ◽  
pp. 681-686 ◽  
Author(s):  
Mohamed Bekheit ◽  
Mohamed Y. Ibrahim ◽  
Wael Tobar ◽  
Ibrahim Galal ◽  
Athar S. Elward
Keyword(s):  
Small Bowel ◽  
Cross Sectional Study ◽  
Anthropometric Parameters ◽  
Anthropometric Measures ◽  
Cross Sectional ◽  
Small Bowel Length ◽  
Bowel Length ◽  
Important Correlation ◽  
The Mean ◽  
The Individual

Abstract Background Variation in the outcome of bariatric surgery is still an unraveled phenomenon. This variation could be multifactorial. Several reports implicate the total small bowel length (TSBL) in this process. However, the basic information regarding the normal bowel length and its relation to the anthropometric parameters of the living subject is scarce. This study aims at reporting the normal total bowel length in living adult humans and its correlation with the anthropometric parameters. Methods This study included 606 participants (380 females and 226 males). Their mean age was 39.8 ± 11 years, weight = 135.7 ± 29.7 kg, height = 165 ± 9 cm, and BMI = 49.5 ± 7.5 kg/m2. The mean TSBL was 630 ± 175 cm. There was a statistically significant but very weak positive correlation but between the TSBL and both weight and height. Males had significantly higher weight and were significantly taller compared with females. TSBL was significantly longer in males at 661.5 ± 186 cm versus 612 ± 164 cm in females. Conclusion The study reports an average TSBL greater than what is reported in the literature from living humans with a greater range of variation. There is no clinically important correlation between the TSBL and the weight and height of the individual participants in this series.

scholarly journals Non-Compliance to Doctors’ Advices among Patients Suffering from Various Diseases: Patients’ Perspectives: A Neglected Issue

2017 ◽  
Vol 18 (1) ◽  
pp. 10-14 ◽  
Author(s):  
Khalida Naz Memon ◽  
Nudrat Zeba Shaikh ◽  
Rafique Ahmed Soomro ◽  
Shazia Rehman Shaikh ◽  
Anza Mansoor Khwaja
Keyword(s):  
Cross Sectional Study ◽  
Oral Route ◽  
Communicable Diseases ◽  
Public Health Issue ◽  
Community Based ◽  
Cross Sectional ◽  
Primary Determinant ◽  
Duration Of Disease ◽  
The Mean ◽  
Compliance To Treatment

Background: An acknowledgement of the patient’s perspectives about compliance towards doctors’ advices is critical in ensuring better results of medical consultation. The compliance to therapies is a primary determinant of treatment success.The authors found a serious dearth of research on this issue.Aim: The aim of the study was to determine the frequency & determinants of non-compliance towards doctors’ advices among study subjects.Method: The current community based descriptive cross sectional study was conducted on 230 subjects suffering from various illnesses. The patients were enrolled using convenience sampling. The data was collected on pre-structured Performa. The data comprises of questions regarding Patients compliance to doctor advises, that may be preventive, promotive and therapeutic care.Results: The mean age of respondents was 36.6 ± 7.4 years. The overall compliance to doctors’ advice was seen among 31.2% subjects. Compliance to treatment advice was 35.8 %; while towards health promotive advices was 29.5% & towards preventive advices against diseases was 28.4 percent.Seventy three percent of the total compliance was seento general practitionersin contrast to consultants i.e. 26.4%.Significant association was seen between compliance & older age (p=0.02), non-infectious diseases (p=0.04), severity of disease (p=0.01), oral route of administration (p=0.00) & shorter duration of disease (p=0.00). The results of association of compliance with gender however remained statistically insignificant.Conclusion: The study indicated that non-compliance towards doctors’ advices is a big public health issue & it should be taken as a hidden risk factor for diseases. The compliance towardsdoctor’sadvice was more prevalent for non-communicable diseases compared to communicable diseases. Additionally, fear of side effects and high cost of medicine were two major reasons for treatment non-compliance.J MEDICINE January 2017; 18 (1) : 10-14

scholarly journals AB0724 IS THERE A LINK BETWEEN RADIOGRAPHIC SACROILIITIS AND HIP INVOLVEMENT IN SPONDYLOARTHRITIS?

2020 ◽  
Vol 79 (Suppl 1) ◽  
pp. 1656.2-1657
Author(s):  
S. Rahmouni ◽  
M. Slouma ◽  
R. Dhahri ◽  
I. Gharsallah ◽  
N. Boussetta ◽  
...  
Keyword(s):  
New York ◽  
Ankylosing Spondylitis ◽  
Structural Damage ◽  
Multivariable Analysis ◽  
Diagnostic Delay ◽  
Symptom Duration ◽  
Sacroiliac Joints ◽  
Cross Sectional ◽  
Significant Difference ◽  
The Mean

Background:Hip involvement is a common feature in spondyloarthritis (SpA). Whether the hip is part of the axial or appendicular skeletal is still a matter of discussion.Objectives:We aimed to assess the relationship between sacroiliitis, spinal and hip involvement in SpA.Methods:Patients with SpA diagnosed according to the assessment of Spondyloarthritis International Society criteria were included in this retrospective cross-sectional study.The modified Stoke Ankylosing Spondylitis Spine Score (mSASSS) and the Bath Ankylosing Spondylitis Radiology Index-spine (BASRI-s) were used to assess the radiographic involvement of the spine.The sacroiliac joints were scored according to the modified New York criteria.Radiological hip involvement was scored using the Bath Ankylosing Spondylitis Radiology Index hip (BASRI-h).Patients were divided into two groups: G0 including patients without hip involvement and G1 patients with hip involvement.Results:We included 112 patients with a sex ratio of 2.4. The average SpA symptom duration was 9.33 ± 8.93 years. The diagnostic delay was 42.92 ± 52 months.Radiographic hip involvement was noted in 39.28% of cases. It was bilateral in 31 patients (70.4%). The total number of coxitis was 75. Severe and moderate hip involvement (BASRI-h ≥ 3) affected 21 hips. The most common radiographic pattern was early coxitis (n=31, 41.3%) followed by the destructive form (n=22, 29.3%, mimicking-osteoarthritis form (n=15, 20%), condensing form (n=5, 6.6%) and ankylosing form (n=2, 2%).Radiographic sacroiliitis was noted in 75.8% of patients. It was bilateral in 91.7% of cases. Among the 161 sacroiliac joints fulfilling the m-New-york criteria, 32.9% had grade 4 and 37.2% had grade 3.The mean mSASSS was 10.26 ± 15. The mean BASRI-t, BASRI-C, and BASRI-L were 3.99 ± 2.9, 0.89 ± 1.3, and 1.1 ± 1.3 respectively.Radiographic sacroiliitis was more common in patients with hip involvement (G1) (90.9% vs 68.2%, p=0.00). Patients in G1 had higher mSASSS (15.78 ± 18.24 vs 6.29 ± 11.85, p=0.01), BASRI-L (1.73±1.46 vs 0.75 ± 1.131, p=0.009), and BASRI-s (5.46 ± 3.02 vs 3.19 ± 2.46, p< 10-3) than patients in G2. There was no significant difference between the two groups regarding the BASRI-C.Multivariable analysis revealed that radiographic sacroiliitis was associated with hip involvement (OR=14.81, 95%, [1.1-198], p=0.042).When comparing patients with severe and moderate hip involvement (BASRI-h ≥ 3) and those with mild involvement, we didn’t find significant differences regarding BASRIs, BASR-L, BASRI-c, mSASSS, and sacroiliac involvement.Conclusion:As reported in previous studies [1], we concluded that structural axial lesions were higher in patients with coxitis. Structural damage to the sacroiliac joint in SpA was predictive of hip involvement.We suggest that sacroiliitis, spinal and hip involvement are part of the same spectrum.References:[1]Chen H-A, Chen C-H, Liao H-T, Lin Y-J, Chen P-C, Chen W-S, et al. Factors associated with radiographic spinal involvement and hip involvement in ankylosing spondylitis. Semin Arthritis Rheum. 2011;40 (6):552-8Disclosure of Interests:None declared

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