scholarly journals Medicinal plants and natural products can play a significant role in mitigation of mercury toxicity

2018 ◽  
Vol 11 (4) ◽  
pp. 247-254 ◽  
Author(s):  
Sanjib Bhattacharya

Abstract Mercury is a heavy metal of considerable toxicity. Scientific literature reveals various plants and plant derived natural products, i.e., phytochemicals, which can alleviate experimentally induced mercury toxicity in animals. The present review attempts to collate those experimental studies on medicinal plants and phytochemicals with ameliorative effects on mercury toxicity. A literature survey was carried out by using Google, Scholar Google, Scopus and Pub-Med. Only the scientific journal articles found in the internet for the last two decades (1998–2018) were considered. Minerals and semi-synthetic or synthetic analogs of natural products were excluded. The literature survey revealed that in pre-clinical studies 27 medicinal plants and 27 natural products exhibited significant mitigation from mercury toxicity in experimental animals. Clinical investigations were not found in the literature. Admissible research in this area could lead to development of a potentially effective agent from the plant kingdom for clinical management of mercury toxicity in humans.


Author(s):  
V. I. Evdokimov ◽  
A. S. Kourov

Relevance.According to the Federal Statistics Service (Rosstat), (315.8 ± 8.5) thousand thermal and chemical burns or (220.6 ± 6.5) burns per 100 thousand people of the country’s population were recorded annually in Russia in 2005–2015. These injuries account for 2.4 % of the structure of all injuries in Russia.Intention.Analysis of the content of scientific journal articles of domestic authors on burn injuriesMethodology.We conducted a search in the electronic database of the Scientific Electronic Library, which made it possible to identify in 2005–2017 1649 scientific journal articles of domestic authors. The average annual number of articles on burn injury indexed in the Russian Science Citation Index was (127 ± 13). There is an increase in the interest of researchers to the problems of burns. The content of the articles correlated with the developed classifier for burn injury.Results and Discussion.General questions of burn injuries were described in 1.6 %, problems of organization of medical care for burn victims – in 4.9 %, characteristics of burn injuries – in 42.9 %, information on diagnostics, treatment, probable complications and rehabilitation of victims – in 41.3 %, experimental studies of burn injury in animals – in 9.3 % of publications. The presented indicators reflected the content of the articles, and, to some extent, objective data. For example, superficial and limited burns were studied to a lesser extent, although they actually prevail. As a rule, the object of research was complex cases that could be of increased interest among readers. The weighted average impact factor of the journals in which the articles were published was 0.304, the average number of citations per article was 1.42, 42.6 % of the articles were cited at least once, Hirsch index was 15. Some authors used inadequate study design. When preparing publications, the groups of authors were often redundant, which resulted in a significant decrease in the number of articles and citations per 1 coauthor.Conclusion. The study helps optimize research in the field of burn injuries. Among the created array of articles, 74.2 % of publications had a full text, 69.4 % of articles were provided free of charge to registered readers of the Scientific Electronic Library.



2019 ◽  
Vol 12 (2) ◽  
pp. 89-92 ◽  
Author(s):  
Sanjib Bhattacharya

Abstract Lead is a toxic heavy metal and there is no specific, safe and efficacious therapeutic management of lead toxicity. Scientific literature reported that some probiotic microorganisms alleviated experimentally induced lead toxicity. The present review attempts to collate the experimental studies on probiotics with ameliorative effects. Literature survey revealed that four (4) types of probiotic microorganisms exhibited significant protection from lead toxicity in experimental pre-clinical studies. No clinical study with significant outcome was found in the literature. From the outcomes of the preclinical studies it appears that probiotics are prospective for alleviation and treatment of lead toxicity.



Oryx ◽  
2010 ◽  
Vol 44 (3) ◽  
pp. 358-365 ◽  
Author(s):  
Bálint Bajomi ◽  
Andrew S. Pullin ◽  
Gavin B. Stewart ◽  
András Takács-Sánta

AbstractWe examined the literature on animal reintroductions to assess the challenges facing individual conservation practitioners who wish to access, synthesize and interpret available evidence to inform their decision making. We undertook an extensive search in eight electronic literature databases, using seven different keyword combinations, and added the content of four bibliographies on reintroductions. We found 3,826 potentially relevant publications totalling at least 29,290 pages of text. Taxonomic bias is apparent in the distribution of general and conservation scientific literature and in reintroduction programmes. We examined whether the literature on reintroductions is biased in a similar way. Comparing the distribution of reintroduction publications to numbers of species, reintroduction programmes and the general conservation literature, there is a marked taxonomic bias favouring vertebrates, especially birds and mammals. The bias in relation to reintroduction programmes is surprising and indicates that managers working with invertebrates and amphibians are less willing and/or less able to publish their results than those working with mammals and birds. The reasons for this are unclear. The growth of the cumulative body of literature can be depicted by a sigmoid curve. Almost 40% of the items were scientific journal articles distributed across 335 journals. The large, ever-growing and dispersed evidence base results in an increased need for reviews, which must be systematic to minimize bias.



Author(s):  
Wissem Aidi Wannes ◽  
Moufida Saidani Tounsi ◽  
Brahim Marzouk

AbstractCancer is a major public health problem in the world. The use of the medicinal plants in cancer prevention and management is frequent in Africa, especially in Tunisia, and it is transmitted from generation to generation within cultures. Many previous studies showed that a wide range of Tunisian medicinal plants exerted cytotoxic and anticancer activity. A comprehensive review was conducted to collect information from scientific journal articles, including indigenous knowledge researches, about Tunisian medicinal plants used for the prevention and management of cancer. The aim of this review article is to provide the reader with information concerning the importance of Tunisian medicinal plants in the prevention and management of cancer and to open the door for the health professionals and scientists working in the field of pharmacology and therapeutics to produce new drug formulations to treat different types of cancer.



2020 ◽  
Vol 11 (SPL1) ◽  
pp. 1278-1285
Author(s):  
Mohamed Yafout ◽  
Amine Ousaid ◽  
Ibrahim Sbai El Otmani ◽  
Youssef Khayati ◽  
Amal Ait Haj Said

The new SARS-CoV-2 belonging to the coronaviruses family has caused a pandemic affecting millions of people around the world. This pandemic has been declared by the World Health Organization as an international public health emergency. Although several clinical trials involving a large number of drugs are currently underway, no treatment protocol for COVID-19 has been officially approved so far. Here we demonstrate through a search in the scientific literature that the traditional Moroccan pharmacopoeia, which includes more than 500 medicinal plants, is a fascinating and promising source for the research of natural molecules active against SARS-CoV-2. Multiple in-silico and in-vitro studies showed that some of the medicinal plants used by Moroccans for centuries possess inhibitory activity against SARS-CoV or SARS-CoV-2. These inhibitory activities are achieved through the different molecular mechanisms of virus penetration and replication, or indirectly through stimulation of immunity. Thus, the potential of plants, plant extracts and molecules derived from plants that are traditionally used in Morocco and have activity against SARS-CoV-2, could be explored in the search for a preventive or curative treatment against COVID-19. Furthermore, safe plants or plant extracts that are proven to stimulate immunity could be officially recommended by governments as nutritional supplements.



2019 ◽  
Vol 20 (5) ◽  
pp. 354-365 ◽  
Author(s):  
Víctor M. Muñoz-Pérez ◽  
Mario I. Ortiz ◽  
Raquel Cariño-Cortés ◽  
Eduardo Fernández-Martínez ◽  
Leticia Rocha-Zavaleta ◽  
...  

Background:Worldwide, the progress in reducing neonatal mortality has been very slow. The rate of preterm birth has increased over the last 20 years in low-income and middle-income countries. Its association with increased mortality and morbidity is based on experimental studies and neonatal outcomes from countries with socioeconomic differences, which have considered implementing alternative healthcare strategies to prevent and reduce preterm births.Methods:Currently, there is no widely effective strategy to prevent preterm birth. Pharmacological therapies are directed at inhibiting myometrial contractions to prolong parturition. Some drugs, medicinal plants and microorganisms possess myorelaxant, anti-inflammatory and immunomodulatory properties that have proved useful in preventing preterm birth associated with inflammation and infection.Results:This review focuses on the existing literature regarding the use of different drugs, medicinal plants, and microorganisms that show promising benefits for the prevention of preterm birth associated with inflammation and infection. New alternative strategies involving the use of PDE-4 inhibitors, medicinal plants and probiotics could have a great impact on improving prenatal and neonatal outcomes and give babies the best start in life, ensuring lifelong health benefits.Conclusion:Despite promising results from well-documented cases, only a small number of these alternative strategies have been studied in clinical trials. The development of new drugs and the use of medicinal plants and probiotics for the treatment and/or prevention of preterm birth is an area of growing interest due to their potential therapeutic benefits in the field of gynecology and obstetrics.



Author(s):  
Annika Lonkila ◽  
Minna Kaljonen

AbstractIncreasing concerns for climate change call for radical changes in food systems. There is a need to pay more attention to the entangled changes in technological development, food production, as well as consumption and consumer demand. Consumer and market interest in alternative meat and milk products—such as plant based milk, plant protein products and cultured meat and milk—is increasing. At the same time, statistics do not show a decrease in meat consumption. Yet alternatives have been suggested to have great transitional potential, appealing to different consumer segments, diets, and identities. We review 123 social scientific journal articles on cell-based and plant-based meat and milk alternatives to understand how the positioning of alternatives as both same and different in relation to animal-based products influences their role within the protein transition. We position the existing literature into three themes: (1) promissory narratives and tensions on markets, (2) consumer preferences, attitudes, and behavioral change policies, (3) and the politics and ethics of the alternatives. Based on our analysis of the literature, we suggest that more research is needed to understand the broader ethical impacts of the re-imagination of the food system inherent in meat and milk alternatives. There is also a need to direct more attention to the impacts of meat and milk alternatives to the practices of agricultural practices and food production at the farm-level. A closer examination of these research gaps can contribute to a better understanding of the transformative potential of alternatives on a systemic level.



Author(s):  
Rostam Jalali ◽  
Amin Hosseinian-Far ◽  
Masoud Mohammadi

Abstract Background Translating research into practice is a central priority within the National Institutes of Health (NIH) Roadmap. The underlying aim of the NIH Roadmap is to accelerate the movement of scientific findings into practical health care provisions through translational research. Main text Despite the advances in health sciences, emerging infectious diseases have become more frequent in recent decades. Furthermore, emerging and reemerging pathogens have led to several global public health challenges. A question, and to an extent a concern, arises from this: Why our health care system is experiencing several challenges in encountering the coronavirus outbreak, despite the ever-growing advances in sciences, and the exponential rise in the number of published articles in the first quartile journals and even the ones among the top 1%? Conclusion Two responses could be potentially provided to the above question: First, there seems to be a significant gap between our theoretical knowledge and practice. And second that many scholars and scientists publish papers only to have a longer list of publications, and therefore publishing is viewed as a personal objective, rather than for improving communities’ public health.



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