scholarly journals Gasping on Oxygen: A Case Report on Toxic Methemoglobinemia

2021 ◽  
Vol 6 (2) ◽  
pp. 112-115
Author(s):  
Mahavishnu Sahadevan ◽  
Menaka Mahendran ◽  
Subasini Govindan ◽  
Thilagavathi Thanusia Viswanathan

Abstract We report the case of a 27-year-old male patient who presented with refractory hypoxemia following the alleged inhalation of an unknown substance. The patient appeared to show worsening cyanosis despite increment of supplemental oxygenation. A drawn sample of the patient’s blood appeared chocolate brown in color, and disparity was noted between the patient’s oxygen saturation (SaO2) in his blood against the pulse oximetry (SpO2) reading. A diagnosis of toxic methemoglobinemia was established following elevated levels of methemoglobin discovered in his blood. The patient was started on methylene blue and instantaneously recovered without any complications. Methemoglobinemia should be suspected in any patient with refractory cyanosis, and early recognition of this condition could be potentially lifesaving.

1986 ◽  
Vol 65 (Supplement 3A) ◽  
pp. A133 ◽  
Author(s):  
A. Sidi ◽  
W. R. Rush ◽  
D. A. Paulus ◽  
N. Gravenstein ◽  
R. F. Davis

2021 ◽  
Vol 11 (2) ◽  
pp. 148-152
Author(s):  
Rajashish Chakrabortty ◽  
Samia Rahman ◽  
Rawnak Jahan ◽  
Abir Hasan Dip ◽  
Mohammed Mirazur Rahman

Pulmonary fibrosis is becoming a recognized complication of coronavirus disease 2019 (COVID-19). Patients with pulmonary fibrosis may present with dry cough, shortness of breath, nail clubbing, low oxygen saturation. We report a case of a 40-year-old male patient with pulmonary fibrosis due to COVID- 19. Clinical examination showed that the patient was dyspneic with low oxygen saturation and there was bilateral inspiratory crepitation in the lower part of his chest. High resolution computed tomography showed bilateral multifocal patchy ground-glass opacities, consolidation with peripheral and basal distribution, sub-pleural fibrotic bands and vascular thickening (almost 40-45% of parenchymal involvement). We prescribed him an antifibrotic drug, nintedanib and there was a significant clinical and radiological improvement after 15 days of treatment. Nintedanib may have novel therapeutic role in preventing COVID-19 associated fibrosis. Birdem Med J 2021; 11(2): 148-152


2017 ◽  
Vol 40 (2) ◽  
pp. 85-91
Author(s):  
Mohammad Abdullah Al Mamun ◽  
Manzoor Hussain ◽  
Suntanu Kumar Kar ◽  
Rezoana Rima ◽  
Abdul Jabbar

Background: Screening for congenital heart diseases (CHD) in newborn babies aid in early recognition, with the prospect of improved outcome. Currently there is no effective screening protocol for this condition. Pulse oximetry is highly specific for detection of critical CHD with moderate sensitivity that meets criteria for universal screening.Objective: To evaluate the use of pulse oximetry as a screening tool in early detection of critical CHD specially duct dependent critical CHD in asymptomatic newborn babies.Methodology: A cross sectional study conducted in Dhaka Shishu (Children) Hospital from October 2014 to June 2015. Newborns attended outpatient department or admitted in different wards with having gestational age >35 weeks and age between 24-48 hours were included and pulse oximetry screening was done. Oxygen saturation measurement <90%, or oxygen saturation measurements <95% in both extremities on three consecutive measurements separated by one hour, or a >3% absolute difference in oxygen saturation between the right hand & foot on three consecutive measurements was considered as pulse oximetry screening positive. Routine neonatal examination was done and clinical evidence of CHD was noted. Echocardiogram was done to rule out CHD. Data were analyzed by using SPSS and sensitivity, specificity and predictive values were calculated.Result: Total 510 neonate were screened during the data collection period. Mean age at screening was 34.99±8.4 hours, male were 322(63.1%) and female were 188(36.9%). Among the neonates 28(5.49%) were found pulse oximetry screening positive and 25(4.90%) were suspected as CHD by routine neonatal examination. Critical CHD were found in 21 cases out of 28 screening positive cases among them duct dependent critical CHD was found in 11 cases. Sensitivity of pulse oximetry to identify critical CHD was 77.77% and specificity was 98.55%. Sensitivity of pulse oximetry to identify duct dependent critical CHD was 78.57% and specificity 96.57%.Conclusion: Pulse oximetry is a good screening test for early identification of duct dependent critical CHD for those who have no obvious feature. So in resource poor country like Bangladesh if all neonatal health setup use pulse oximetry screening within 24-48 hours of life, it will increase early identification of duct dependent critical CHD.Bangladesh J Child Health 2016; VOL 40 (2) :85-91


2020 ◽  
Vol 2020 ◽  
pp. 1-4
Author(s):  
Leah S. Heidenreich ◽  
Jennifer L. Oliveira ◽  
Peter J. Holmberg ◽  
Vilmarie Rodriguez

Pulse oximetry is routinely used in the newborn nursery for clinical monitoring and to detect critical congenital heart disease. The differential diagnoses for reduced peripheral oxygen saturation in an infant include congenital heart disease, respiratory distress syndrome, transient tachypnea of the newborn, persistent pulmonary hypertension of the newborn, meconium aspiration syndrome, pneumonia, pneumothorax, and sepsis. The diagnostic evaluation for neonatal hypoxemia can be invasive and expensive. When this evaluation is unrevealing, other interventions may be tried without clear benefit to the patient, including, but not limited to, supplemental oxygen. Therefore, it is important to consider alternative, albeit rare, diagnoses, including hemoglobinopathies with abnormal oxygen binding properties. Mutations in the structure of alpha- and beta-globin chains can alter the affinity of hemoglobin for oxygen, and changes in oxygen affinity may result in changes in the oxygen saturation detected by pulse oximetry. These changes may or may not be of clinical significance. This case report describes Hemoglobin Sunshine Seth, a rare low-oxygen-affinity hemoglobin variant presenting as reduced peripheral oxygen saturation in an otherwise well-appearing infant male.


2016 ◽  
Vol 3 (2) ◽  
Author(s):  
Mahesh M M ◽  
Dr. Johnson Alex

42 years old male patient referred from neurology department, working as a teacher, educated up to MSc, premorbidly anxious personality, family history mental illness (first degree relatives), comes from MSES with presenting complaints of difficulty in writing or copying since seven years. Disability progressed and he was unable to write even a few words legibly and could not hold object which leads to anxiety and dependency. When the patient was examined at Neurology OPD, find out that he has normal sensory and motor nerve functions. The present treatment involved the use of Bahaviour therapy. The findings in this case is very encouraging and studies with large sample sizes can be considered for further conclusive evidence on the treatment of writer’s cramp.


Author(s):  
Nirmal P. Alodaria ◽  
S. N. Gupta ◽  
Dhaval Dholakiya ◽  
Kaushik B. Vyas

Obesity is burning health issue for society nowadays. In Sutrasthana of Charaka Samhita, in different Adhyaya (eg. Astauninditiya, Langhanabrumhaniya, Santarpaniya) causes, symptoms and treatment of Sthaulya are described. As an alternative approach, Ayurvedic treatment may serve as promising modality. A 17 years old male patient came in P.D. Patel Ayurveda Hospital on 22th May 2017. Patients weight was 114.8 kg and BMI was 37.51 which fairly included in obesity category according to NHI guidelines. He also had some associated complaints like exertional dyspnoea, increased appetite, excessive perspiration. He was treated with Snehana (Aabhyantara and Bahya), Swedana, Vamana, Virechana, Niruha Basti, Udvartana along with oral medicines like Varunaadi Kwatha, Arogyavardhini Vati, Triphala Guggulu, and Navayasa Lauha along with prescribed dietary regimes and life style modification. He lost about 9.7 kg of weight, which was 105.1 kgs and BMI was 34.34 only in 26 days without any complications.


2021 ◽  
Vol 37 (1) ◽  
Author(s):  
Shreya Agarwal ◽  
Nimish Gupta

Abstract Background Leech infestation in the nose or nasopharyngeal region is a rare occurrence. The most common known cause is drinking water from natural water sources like ponds and rivers. Its hidden location of attachment in the nasopharynx and its uncommon occurrence make it easy to miss during diagnosis. Case presentation We present a case of a 61-year-old male patient with recurrent unilateral epistaxis without any apparent cause. He was diagnosed with leech infestation in the nasopharynx on endoscopic examination. This article reports the management of nasopharyngeal leech infestation and safety measures for this animate foreign body retrieval. Conclusion A vigilant approach, thorough history, and examination are a must. Though leeches are simple to remove most of the time, certain necessary precaution should be kept in mind for better management and prevention of further complications.


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