Simulation of crop systems has evolved from a neophyte science into a robust and increasingly accepted discipline. Our vision is that crop systems simulation can serve important roles in agriculture and environment. Important roles and uses of crop systems simulation are in five primary areas: (1) basic research synthesis and integration, where simulation is used to synthesize our understanding of physiology, genetics, soil characteristics, management, and weather effects, (2) strategic tools for planning and policy to evaluate strategies and consequences of genetic improvement or resource management, (3) applications for management purposes, where crop systems simulations are used to evaluate impacts of weather and management on production, water use, nutrient use, nutrient leaching, and economics, (4) real time decision support to assist in management decisions (irrigation, fertilization, sowing date, harvest, yield forecast, pest management), and (5) education in class rooms and farms, to explain how crop systems function and are managed.