scholarly journals HUBUNGAN ANTARA DIABETES MELLITUS TIPE II DENGAN DERAJAT OSTEOARTHRITIS LUTUT

Author(s):  
Maruf Hari Subroto ◽  
Basuki Supartono ◽  
Ryan Herardi

Osteoarthritis is a degenerative disease that cause damage to joint cartilage damage. Osteoarthritis affects 151,4 million people in the world, including 27,4 million in Southeast Asia. Osteoarthritis is a disease that is a burden on public health and the country. The prevalence of osteoarthritis is one in four people aged 50 years and individuals aged 65 years are more at risk of developing calcification of the knee joint. Risk factors such as type II Diabetes Mellitus are observed in one of osteoarthritis research. A hispanic study explained the prevalence of osteoarthritis patient are twice as much in diabetic patient than non-diabetic patient. A score of 6.5% of HbA1c test is required to diagnose diabetes. The goal of this study is to find out the connection of type 2 diabetes mellitus and knee osteoarthritis. This research uses observational analytic with cross sectional research design with a total of 45 patient from Orthopedic clinic of Al – Fauzan General Hospital in 2016 – 2019 and analyzed with chi square test. According to the result, the most group of age is elderly about 34 people (75,6%), the most group of gender is women about 34 people (75,6%), the most group of HbA1c is non-diabetes mellitus group about 30 people (66,7%), the most group of osteoarthritis stage is severe de (4) about 28 people (62,2%), and there is no connection between type II diabetes mellitus with the stage of knee osteoarthritis with p value of 0,828 (p > 0.05). this research shows no significant correlation between type II diabetes mellitus and the stage of knee osteoarthritis. Keywords : Knee Osteoarthritis; HbA1c; Type II Diabetes Mellitus AbstrakOsteoarthritis adalah penyakit degeneratif yang disebabkan kerusakan tulang rawan sendi. Osteoarthritis dialami 151,4 juta orang di dunia dan 27,4 juta orang di Asia Tenggara. Osteoarthritis merupakan penyakit yang menjadi beban kesehatan masyarakat dan negara. Prevalensi terjadinya osteoarthritis yaitu satu dari empat orang berusia 50 tahun dan individu berusia lebih dari 65 tahun beresiko mengalami pengapuran sendi lutut. Penelitian osteoarthritis mengamati faktor risiko terjadinya osteoarthritis seperti diabetes mellitus tipe 2. Studi Hispanik menjelaskan prevalensi penderita osteoarthritis dua kali lebih banyak terjadi pada penderita dengan diabetes dibandingkan penderita tanpa diabetes. Pemeriksaan HbA1c direkomendasikan untuk mendiagnosis diabetes, dengan batas nilai 6,5 %. Tujuan penelitian ini adalah untuk mengetahui hubungan antara diabetes mellitus tipe II dengan derajat osteoarthritis lutut. Penelitian ini menggunakan analitik observasional dengan desain penelitian potong lintang dengan jumlah sampel 45 pasien di Poli Orthopedi Rumah Sakit Umum Al – Fauzan tahun 2016 – 2019 dan dianalisa menggunakan uji kai kuadrat. Berdasarkan hasil penelitian, usia terbanyak adalah lansia yaitu 34 orang (75,6 %), jenis kelamin terbanyak adalah perempuan yaitu 34 orang (75,6 %), HbA1c terbanyak adalah non diabetes mellitus yaitu 30 orang (66,7 %), derajat osteoarthritis lutut terbanyak adalah derajat berat (4) yaitu 28 orang (62,2 %), dan tidak terdapat hubungan yang bermakna antara diabetes mellitus tipe II dengan derajat osteoarthritis lutut dengan nilai p sebesar 0,828 (p > 0,05). Penelitian ini menunjukan tidak terdapat hubungan yang bermakna antara diabetes mellitus tipe II dengan derajat osteoarthritis lutut

2019 ◽  
Vol 4 (2) ◽  
pp. 178
Author(s):  
Elis Anggeria ◽  
Patimah Sari Siregar

<p><em>Diabetes mellitus (DM) is a group of metabolic diseases characterized by high levels of glucose in the blood (hyperglycemia) that occurs due to impaired insulin secretion, decreased insulin action, or a result of both. Self-acceptance is the ability and desire of individuals to live with all the characteristics themselves against diabetes mellitus. This study aims to determine the effectiveness of diabetic ulcer treatment on self-acceptance of Type II Diabetes Mellitus patients at Asri Wound Care Center Medan. This study uses quantitative research methods with a quasi-experimental design through the one-group pretest-posttest design approach. The population in the study as many as 20 people, with sampling techniques using saturated sampling, the research sample amounted to 20 people. This study uses a nonparametric statistical test that is paired t-test. The results of research on self-acceptance of patients with type II diabetes mellitus before treatment of diabetic ulcers showed that the majority of self-acceptance was not good, and the self-acceptance of patients after treatment of diabetic ulcers obtained the majority of good self-acceptance. The effectiveness of diabetic ulcer treatment on self-acceptance of type II diabetes mellitus patients obtained significance value p-value = 0.00 (p-value &lt;0.05) then H0 was rejected. This means that there are differences in self-acceptance of type II Diabetes mellitus patients before and after diabetic ulcer treatment at Asri Wound Care Center Medan. Future researchers are expected to discuss more deeply about the factors that affect the self-acceptance of diabetes mellitus patients who are undergoing treatment for diabetic ulcers.</em></p>


1992 ◽  
Vol 35 (3) ◽  
pp. 336-342 ◽  
Author(s):  
Claire A. Horn ◽  
John D. Bradley ◽  
Kenneth D. Brandt ◽  
Donald L. Kreipke ◽  
Sally D. Slowman ◽  
...  

2019 ◽  
Vol 26 (12) ◽  
pp. 2040-2043
Author(s):  
Munir Ahmed ◽  
Abdul Hayee ◽  
Shahla Afsheen Memon ◽  
Ismail Salim Memon ◽  
Abdul Qayoom Memon

Objectives: To determine the frequency of diastolic dysfunction in patients presenting with type II Diabetes Mellitus. Study Design: Cross sectional study. Setting: Sheikh Zayed Hospital, Rahim Yar Khan. Period: From 01-01-2017 to 30-06-2017. Material & Methods: In this study the cases were selected via non probability consecutive sampling of both male and female gender with age more than 40 years having type II DM of at least more than 2 years were included. The cases suffering from type I DM, gestational DM and those with HTN, end stage kidney and liver failure were excluded. Trans thoracic echocardiography was done to label diastolic dysfunction and was labelled as yes when the E/A ratio was <0.8. The data was analysed using chi square test and p value less than 0.05 was taken as significant. Results: In this study, 100 cases of type II DM were included with mean age of 51.31±7.89 years at presentation. There were 61% males and 39% females. Diastolic dysfunction was observed in 53% of the cases. There was no significant difference in terms of gender where it affected 56.41% of females with p= 0.92. Diastolic dysfunction was more in cases that had duration of DM more than 3 years affecting 48 (70.58%) cases with p= 0.001 and it was also significantly high in cases that had BMI more than 30 where it was seen in 40 (70.17%) of cases with p= 0.001. Conclusion: Diastolic dysfunction seen in half of the cases suffering from type II DM and it is significantly high in cases that had duration of DM more than 3 years and BMI more than 30.


2021 ◽  
Vol 16 (2) ◽  
pp. 196-203
Author(s):  
Nassr Eldin M. A. shrif ◽  
Ahmed Mohamed Ahmed Dawood ◽  
Abdelmahmoud Mokhtar Bashir ◽  
Hassan Mohammed Khair Ibrahim ◽  
Abd Elgadir A Altoum

Background: Chromium is an essential micronutrient which is required for the normal functioning of insulin and regulation of blood sugar levels. It acts as a vital antioxidant for maintaining insulin homeostasis. In diabetes mellitus, the free radical production is increased and levels of antioxidants like chromium, vanadium, selenium and manganese are reduced. Aim: To study the level of serum chromium level in patients with type 2 diabetes mellitus and its association with glycemic control. Materials and Methods: One hundred and twenty individuals were enrolled in this study, classified into 60 type II diabetes mellitus (type II DM) patients and 60 apparently health as control group. Serum chromium and Glycosylated Hemoglobin (HbA1c) level were measured using atomic absorption spectrometry and Ichroma. Results: The results showed significant decrease in serum chromium level in type II DM patients (0.0151±0.005) when compared with healthy group (0.122±0.691) with p-value (0.002). In addition to that there was significant decrease in mean concentration of serum chromium level in controlled diabetic patients (0.0206± 0.003) when compared with uncontrolled diabetic patients (0.0120±0.002) with P-value (0.04).Also there was significant positive correlation between chromium level and Body Mass Index (BMI) (R-value 0.450, P-value 0.014), and significant negative correlation between chromium level and age (R-value- 0.660, P-value 0.011) , a significant strong negative correlation between chromium level and HbA1c (R-value -0.843, P-value 0.0260). Conclusion: The study concluded that, serum chromium level is significantly decrease in type II DM.


Author(s):  
Hardik N Javia ◽  
Milav H Bhavsar ◽  
Bhavesh R Sadariya ◽  
Amitkumar V Maheshwari ◽  
Hariom Sharma

Introduction: Ischaemic Heart Disease (IHD) or Coronary Artery Disease (CAD) is the most prevalent chronic disease and the main leading cause of death in the world, with more than half a million newly diagnosed IHD patients each year. Central to this are disorders of lipoprotein metabolism. Apolipoprotein B (Apo B) and Apolipoprotein A1 (Apo A1) are structural and functional components of lipoprotein particles that serve as transporters of cholesterol. Apo B and Apo A1 are among the emerging markers for Cardiovascular Diseases (CVD). Routine conventional lipid profile does not incorporate these markers. Aim: To determine the level of Apo A1 and Apo B in patients of IHD with or without Type II Diabetes Mellitus (T2DM) and analyse the significance of these parameters over the conventional lipid profile. Materials and Methods: The case-control study was conducted at Government Medical College, Bhavnagar, Gujarat, India from July 2013 to December 2013. The study consists of 100 participants including 50 having IHD only (Group I), 50 having IHD with T2DM (Group II) as study groups and 50 healthy individuals (Group III) as control. Various biochemical parameters including Apo B and Apo A1 were analysed and statistically evaluated to come to conclusion. Results: The demographic details of the participants which shows no significant different in age and gender among groups I, II and III. Apo B and A1 were elevated in group I and II and were found highly significant (p-value <0.0001) as compared to the group III. There was positive correlation of serum Apo B levels with total cholesterol (r=0.495, p-value <0.0001), Low-Density Lipoproteins (LDL-C) (r=0.526, p-value <0.0001) and Apo A1 (r=0.685, p-value <0.0001) in group I and LDL-C (r=0.468, p-value=0.001) and Apo A1 (r=0.754, p-value <0.0001) in group II. Similarly, Apo A1 levels were positively correlated with Apo B (r=0.685, p<0.0001) in group I and LDL-C (r=0.305, p-value=0.031) and Apo B (r=0.754, p-value <0.0001) in group II. Conclusion: As the Apo B and Apo A1 cover both atherogenic and antiatherogenic lipid parameters respectively, it can be used as a better predictor of development of IHD with and without T2DM in comparison to conventional parameters of lipid profile.


2017 ◽  
Vol 3 (2) ◽  
pp. 79-86
Author(s):  
Ravi Shankar Reddy

Background: Patients withType II diabetes mellitus are showed to affect the sensory, reflex and motor systems in distal extremities. Studies have examined the mechanosensitivity and vibration threshold (VT) in type II diabetes mellitus patients in the lower limb and compared it with normal individuals. There is scanty literature available in comparison of the VTin the upper limb in type II diabetes mellitus patients with non-diabetic individuals. Methods: Thirty type II diabetic individuals (age - 55.60 ± 9.79 years)and 30 asymptomatic individuals (age - 53.43±9.96) without diabetes mellitus participated in the study. Tester at the baseline for both the groups using a bioesthesiometer measured VT. Bioesthesiometer is capable of deriving a vibration of 100 Hz. Following VTevaluation at the baseline, the tester performed the ULNT1 for all the subjects. During the sequence of the ULNT1, VTwas measured at initial onset of pain (termed as P1) and short of maximum pain (P2) as experienced by the patient. Results:There was a statistical significant difference inVTbetween diabetic and non-diabetic group subjects. VTwas raised in the diabetic group at all the three levelsof evaluation (baseline, P1 and P2) compared to the non-diabetic group with a p value < 0.001. Conclusion: VT of the upper limb is higher in individuals with type II diabetes mellitus as compared to non-diabetic individuals.


2019 ◽  
Vol 26 (06) ◽  
Author(s):  
Muslim Khahro ◽  
Qaimuddin Shaikh ◽  
Mehnaz Baloch ◽  
Surwaich Ali Channa ◽  
Arhama Shah

Objectives: To determine the frequency of dental caries in patients with type II diabetes mellitus. Study Design: Cross sectional study. Setting: Dental Department of Science of Dental Materials Department and Oral Pathology Department. Period: 6 months from October 2016 to February 2017. Material and Methods: All the diagnosed patients of type II diabetes mellitus either gender were selected for the study. Complete dental clinical examination and duration of diabetes were carried out. Dental caries were categorized as mild moderate and severe. Duration of diabetes was categorized as < years and > 5 years. All the data was recorded in the self-made proforma. Results: In this study total 58 patients were selected with history of type II diabetes mellitus; patient’s mean age was 46.36+5.34 years. Male gender was found in the majority 38(65.5%). Majority of the cases 37(63.8%) were found with low socioeconomic status. 26(44.8%) patients had history of type II diabetes mellitus less than 5 years, 32(55.2%) were with more than 5 years history of diabetes. 15.51% patients were without dental caries, 37.39% patients were with mild, 34.4% had moderate and 12.06% patients were with severe dental caries. No significant difference was found in severity of dental caries when compared with duration of diabetes p-value 0.93.  Conclusion: We concluded that there are a big prevalence dental caries among patients with type II diabetes mellitus, while severity of dental caries was insignificantly associated with duration of diabetes.


2019 ◽  
Vol 10 (2) ◽  
pp. 911-915
Author(s):  
Yurida Yurida ◽  
Zaqyyah Huzaifah

Latar Belakang: Diabetes merupakan penyakit yang jumlah penderitanya semakin bertambah dan merupakan ancaman serius bagi pembangunan kesehatan nasional. Salah satu jenis latihan fisik yang direkomendasikan untuk penderita diabetes melitus tipe II adalah jalan kaki.Tujuan: Penelitian ini untuk menganalisis pengaruh jalan kaki terhadap kadar gula darah pada pasien diabetes mellitus tipe II.Metode: Jenis penelitian ini adalah pra eksprimen dengan pendekatan one group pre and posttest design menggunakan teknik pengambilan sampel purposive sampling. Analisa data melalui uji T Dependen kepada 15 orang responden.Hasil: Rata-rata kadar gula darah sebelum jalan kaki adalah sebesar 238,2 mg/dl sedangkan sesudah jalan kaki rata-rata kadar gula darah sebesar 203,4 mg/dl. Ada pengaruh jalan kaki terhadap kadar gula darah pada pasien diabetes mellitus tipe II (p value = 0,000).Kesimpulan: Perawat diharapkan dapat memberikan pendidikan kesehatan mengenai pengaruh jalan kaki terhadap penurunan kadar gula darah pasien DM tipe II. Background: Diabetes is a disease that the number of sufferers is increasing and is a serious threat to national health development. One type of physical exercise recommended for client with type II diabetes mellitus is walking. Objective: This research is to analyze the effect of walking on blood sugar levels in client with diabetes mellitus type II.Method: The research design is pre-experiment with one group pre and posttest design approach and purposive sampling technique. Data analysis through Dependent T test to 15 people.Result: Clients with type II diabetes mellitus before walking had an average blood sugar level of 238.2 mg/dl while after walking on average blood sugar levels of 203.4 mg/dl. There is influence of walking to blood sugar level of type II diabetes mellitus clients (p value = 0,000).Conclusion: The nurse is expected to give health education about the effect of walking to decrease blood sugar level of DM type II.  Keywords: Walking , Blood sugar level, Diabetes mellitus type II


2020 ◽  
Author(s):  
Eman A.Elmoniem Alhnnan ◽  
Azza O Alawad

Abstract Background: Zinc micronutrient is essential for human health, there is accumulating data that zinc level is altered in both diabetes mellitus and chronic periodontitis, but the exact role of zinc in the pathogenesis of those conditions stay unclear. The present study was done to evaluate the salivary zinc level in chronic periodontitis patients with type II diabetes mellitus and non-diabetics. Methods: A Case-control study was conducted in Khartoum state between June and December 2019 at Khartoum dental teaching hospital, Jaber Abo-alezz diabetic center and Al-Neelain University. Chronic periodontitis was diagnosed with CAL ≥ 3mm. Patients with Hemoglobin A1c ≤ 6.5% were considered as controls for diabetes. Salivary zinc level was assessed in 64 subjects, 26 systemically healthy subjects without chronic periodontitis (Group A), 19 patients with chronic periodontitis otherwise systemically healthy (Group B) and 19 diabetic patients with chronic periodontitis (Group C). Atomic absorption spectrophotometry method was utilized to measure the zinc level in saliva. The data were statistically analyzed by analysis of variance and Scheffe multiple comparison test utilizing statistical software SPSS version 20. Results: The results showed that salivary zinc level decreased in periodontitis patients with and without type II diabetes mellitus compared to healthy control (P-value < 0.05), whereas there was no statistically significant difference between salivary zinc level in periodontitis patients and diabetic patients with periodontitis(P-value > 0.05).Conclusion: Low salivary zinc level may predispose to the risk of developing chronic periodontitis.


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