scholarly journals Fexofenadine Adsorption by Activated Charcoal Impregnated with Hydrogen Peroxide

2020 ◽  
pp. 1245-1252
Author(s):  
Jasim Humadi Hassen ◽  
Mohammad Singar Ferhan ◽  
Abdalkareem Hamad Ayfan
Keyword(s):  
Hydrogen Peroxide ◽  
Activated Charcoal ◽  
Adsorption Process ◽  
Blue Shift ◽  
Solution Concentration ◽  
Repeated Dose ◽  
Drug Concentrations ◽  
Vis Spectroscopy ◽  
Effects Of Ph ◽  
Drug Solution

The adsorption of fexofenadine drug by activated charcoal powder impregnated with hydrogen peroxide (IAC) to improve its surface properties was investigated. The investigation also aimed to assess the effect of the repeated dose in increasing the amount of the drug adsorbed. The powder activated charcoal was impregnated with H2O2 3%. The effects of pH of the solution, concentration of the drug and time of the reaction parameters were investigated by using UV-Vis spectroscopy. The IAC was brought in contact with the drug solution in different pH (2, 4, 7 and 9), drug concentrations (30, 60, 90 and 120 µg ml-1) and time (15, 30, 45 and 60 minutes). After each experiment, a repeated dose of IAC was introduced into the solution and the adsorption process was repeated. The results showed that the amounts of the drug adsorbed were decreased with increasing the pH and increased with increasing the concentration of solution and time of contact. The adsorption capacity was enhanced to about 70% after the addition of the repeated dose. The study showed a spectrum displacement toward the blue region (blue shift) for the drug supernatant in all experiment parameters, which was almost doubled when a repeated dose was added.

scholarly journals Photoluminescence as a Complementary Tool for UV-VIS Spectroscopy to Highlight the Photodegradation of Drugs: A Case Study on Melatonin

Molecules ◽  
2020 ◽  
Vol 25 (17) ◽  
pp. 3820
Author(s):  
Monica Daescu ◽  
N’ghaya Toulbe ◽  
Mihaela Baibarac ◽  
Alin Mogos ◽  
Adam Lőrinczi ◽  
...  
Keyword(s):  
Alkaline Solution ◽  
Uv Light ◽  
Chemical Compounds ◽  
Solution Concentration ◽  
Isosbestic Point ◽  
Photoluminescence Excitation ◽  
Vis Spectroscopy ◽  
Naoh Solution ◽  
Drug Solution

In this work, a complementary ultraviolet-visible (UV-VIS) spectroscopy and photoluminescence (PL) study on melatonin (MEL) hydrolysis in the presence of alkaline aqueous solutions and the photodegradation of MEL is reported. The UV-VIS spectrum of MEL is characterized by an absorption band with a peak at 278 nm. This peak shifts to 272 nm simultaneously with an increase in the band absorbance at 329 nm in the presence of an NaOH solution. The isosbestic point localized at 308 nm indicates the generation of some chemical compounds in addition to MEL and NaOH. The MEL PL spectrum is characterized by a band at 365 nm. There is a gradual decrease in the MEL PL intensity as the alkaline solution concentration added at the drug solution is increased. In the case of the MEL samples interacting with an alkaline solution, a new photoluminescence excitation (PLE) band at 335 nm appears when the exposure time to UV light reaches 310 min. A down-shift in the MEL PLE band, from 321 to 311 nm, as a consequence of the presence of excipients, is also shown. These changes are explained in reference to the MEL hydrolytic products.

scholarly journals SPECTROSCOPIC EVALUATION OF ACTIVATED CHARCOAL AS A POISON ANTIDOTE FOR GLICLAZIDE DRUG

2018 ◽  
Vol 11 (3) ◽  
pp. 140
Author(s):  
Jasim Hamadi Hassen ◽  
Abdalkareem Hamad Ayfan ◽  
Yaser Mohamad Farhan
Keyword(s):  
Activated Charcoal ◽  
Reaction Times ◽  
Time Dependent ◽  
Acidic Ph ◽  
Time Study ◽  
High Concentration ◽  
Effect Of Ph ◽  
Effects Of Ph ◽  
Drug Solution ◽  
Ph Concentration

 Objective: The aim of the present study is to evaluate the ability of activated charcoal in adsorbing overdosage of gliclazide drug, and to study the effects of pH, concentration and time on this process.Methods: To evaluate the effect of pH, concentration and time; 50 ml of the drug solution (100 mg/L) were allowed to stand with the activated charcoal for 1 h at pH of 1.5, 4, 7, and 9 for pH study. 50 ml of the drug solution concentrations of 25, 50, 75, and 100 (mg/L) were allowed to stand with 1 g activated charcoal for 1 h for concentration study. 50 mg of the drug solution (100 mg/L) were allowed to stand with the activated charcoal for 15, 30, 45, and 60 min for time study. The concentrations of the adsorbed drug were determined spectrophotometrically.Results: The adsorption of the gliclazide drug on activated charcoal was found to be pH, concentration, and time-dependent. The amounts of the drug adsorbed were 3, 0.75, 0.6, and 0.5 mg/g for pHs 1.5, 4, 7, and 9, respectively, for pH study. For concentration study, the amounts adsorbed were 0.15, 0.22, 0.33, and 0.58 mg/g for concentrations 25, 50, 75, and 100 mg/L, respectively. For time study, the amounts were 0.3, 0.4, 0.51, and 0.65 mg/g for reaction times 15, 30, 45, and 60 min, respectively.Conclusion: The best adsorption circumstances of gliclazide drug on activated charcoal that were found; acidic pH, a high concentration of the drug and longtime of contact.

scholarly journals A comparative analysis of in-office vital 6% hydrogen peroxide activated charcoal tooth whitening treatment enhanced with an 810nm diode laser, compared to 35% hydrogen peroxide bleaching

2021 ◽  
Vol 76 (2) ◽  
pp. 64-71
Author(s):  
Shabeer I Hassim ◽  
Tufayl A Muslim
Keyword(s):  
Hydrogen Peroxide ◽  
Diode Laser ◽  
Activated Charcoal ◽  
Research Question ◽  
Treatment Protocol ◽  
Primary Data ◽  
Absorption Enhancement ◽  
Significance Level ◽  
Peroxide Bleaching ◽  
Bleaching Procedure

Laser dental bleaching is considered to be a contemporary approach to enhancing the in-office power bleaching procedure. Objective Investigate if laser enhanced 6% Hydrogen Peroxide (HP) solution is equivalent to 35% HP solution over a two-visit power bleaching treatment protocol. In a randomised double-blinded clinical trial, 43 patients were assigned to a group that received either the laser-enhanced 6% Hydrogen Peroxide (n=21) treatment, or the standard 35% Hydrogen Peroxide (n=22) treatment, over two visits, with a one-week interval. Activated charcoal HP paste was prepared for both groups. The laser enhanced 6% HP group received a dosage of 90 J/cm² per bleaching cycle using 810nm diode laser. Tooth colour was measured at the beginning and end of each session registering parameters L*, a* and b*, and tooth sensitivity. The calculated difference between these Parameters, ∆E, was the primary data focus. The mean ∆E over the treatment duration was used to answer the research question by a t-test to evaluate group differences at 5% significance level. The analysis revealed that the null hypothesis could not be rejected and the results were inconclusive. The observations expound the idea of an absorption enhancement mechanism, rather than a free radical activation, as the technique for improving bleaching outcomes.

scholarly journals Interaction Mechanism between Antibiotics and Humic Acid by UV-Vis Spectrometry

2018 ◽  
Vol 15 (9) ◽  
pp. 1911 ◽  
Author(s):  
Xiaoyu Yuan ◽  
Shengke Yang ◽  
Jie Fang ◽  
Xueli Wang ◽  
Haizhen Ma ◽  
...  
Keyword(s):  
Humic Acid ◽  
Absorption Band ◽  
Interaction Mechanism ◽  
Blue Shift ◽  
Degree Of Polymerization ◽  
Ultraviolet Spectrum ◽  
Red Shift ◽  
Vis Spectroscopy ◽  
Nm Range ◽  
Peak Value

In this study, the interaction between the humus and two antibiotics was studied by UV-Vis spectroscopy to describe the interaction mechanism and the effects of different environmental factors on the mechanism. Results showed that humic acid (HA) containing more aromatic groups was easily associated with antibiotics. In the HA-OTC, with the increase of the concentration of OTC, there were obvious absorption peaks in the 230–260 nm and 330–360 nm range, and the absorption band of the HA ultraviolet spectrum underwent a slight blue shift and the absorption intensity increased, demonstrating that a new ground state complex was generated. In the HA-SD, with the increase of SD concentration, an aromatic structure absorption peak appeared in the 190–220 nm range, and the peak value increased and the absorption band underwent a red shift, and the aromatization of HA decreased, which enhanced the interaction between the antibiotics and HA. With the increase of pH, the absorption band of HA, HA-OTC and HA-SD ultraviolet spectrum suffered a blue shift, the degree of polymerization of HA molecules decreased, and the number of adsorption binding sites increased, which resulted in the interaction of HA with antibiotics being enhanced. The absorption band of HA, HA-OTC and HA-SD displayed a red shift with the increase of ionic strength, which indicated that the repulsion within HA particles was weakened, and the molecular polymerization was strengthened and therefore, the interaction between antibiotics and HA was inhibited. The UV characteristics of the HA, HA-OTC and HA-SD systems were insensitive to the temperature. This study lays the foundation for better studying the effect of humus on the distribution of antibiotic residues in the environment.

scholarly journals Adsorption capability of brewed tea waste in waters containing toxic lead(II), cadmium (II), nickel (II), and zinc(II) heavy metal ions

2020 ◽  
Vol 10 (1) ◽  
Author(s):  
Hakan Çelebi ◽  
Gülden Gök ◽  
Oğuzhan Gök
Keyword(s):  
Heavy Metals ◽  
Adsorption Process ◽  
Low Cost ◽  
Adsorption Capacities ◽  
Tea Waste ◽  
Optimum Ph ◽  
Effects Of Ph ◽  
Equilibrium Data ◽  
Langmuir Isotherm Model ◽  
Adsorption Capability

Abstract Recently, the search for low-cost eco-friendly adsorbents has become one of the main objectives of researchers. The aim of this study was to test the removal of four heavy metals, namely lead (Pb), zinc (Zn), nickel (Ni) and cadmium (Cd), from a simulated watery solution using brewed tea waste as a potentially suitable adsorbent. The effects of pH levels (2.0–6.0), adsorbent amount (0.1–5.0 g), contact times (1–150 min.) were examined throughout the adsorption process. The results of the experiments showed that the heavy metals elimination yields had an inverse relationship with pH and a linear relationship between the other parameters. The optimum pH for the removal of the heavy metals was between 4.0 and 5.0 in the case of the brewed tea waste. Equilibrium times of 2, 10, 30 and 5 min were required for the adsorption of Pb, Zn, Ni, Cd onto Camellia sinensis, respectively. Based on the results of this study it can be said that brewed tea waste has a high potential to remove heavy metals from aqueous solutions. The maximum adsorption capacities were calculated as 1.197, 1.457, 1.163 and 2.468 mg/g, for Pb, Zn, Ni and Cd, respectively, by fitting the equilibrium data to the Langmuir isotherm model.

Photocatalytic Degradation of 2,4,5–TCP in TiO2/UV/H2O2 System

2012 ◽  
Vol 518-523 ◽  
pp. 2649-2652
Author(s):  
Yan Ping Zong ◽  
Xian Hua Liu ◽  
Xi Wen Du ◽  
Yi Ren Lu ◽  
Xiao Xuan Shi
Keyword(s):  
Hydrogen Peroxide ◽  
Photocatalytic Degradation ◽  
Absorption Spectroscopy ◽  
Degradation Mechanism ◽  
Analysis Method ◽  
Photocatalytic System ◽  
Initial Ph ◽  
Effects Of Ph

The photocatalytic degradation of 2,4,5–Trichlorophenol(2,4,5–TCP) in TiO2/UV/ H2O2 photocatalytic system was examined using absorption spectroscopy and GC-MS. It was found that 2,4,5–TCP could be degraded almost completely within 100 min under the conditions of initial pH 3, C(H2O2) = 0.08 mol/L and C(TiO2) = 0.5 g/L. The effects of pH and the concentration of hydrogen peroxide on the degradation of 2,4,5–TCP were also studied. Besides, the degradation mechanism was concluded accorrding to convertional analysis method too.

A Simple Method for Synthesis of PbS Nanoparticles Using 2-Mercaptoethanol as the Capping Agent

2012 ◽  
Vol 31 (6) ◽  
pp. 723-725 ◽  
Author(s):  
Gholamreza Nabiyouni ◽  
Parviz Boroojerdian ◽  
Kambiz Hedayati ◽  
Davood Ghanbari
Keyword(s):  
Electron Microscopy ◽  
Electronic Absorption Spectra ◽  
Blue Shift ◽  
Microscopy Study ◽  
Electron Microscopy Study ◽  
Sulfur Source ◽  
Capping Agent ◽  
X Ray Diffraction ◽  
Simple Method ◽  
Vis Spectroscopy

AbstractLead sulfide nanoparticles were synthesized at room temperature via a simple chemical reaction. In this synthesis, 2-mercaptoethanolwas used as the capping agent and sodium sulfide was used as a sulfur source. The products were characterized by X-ray diffraction (XRD), scanning electron microscopy (SEM), ultraviolet-visible (UV-vis) spectroscopy and Fourier transform infrared (FT-IR) spectroscopy Electron microscopy study showed that without using a capping agent the bulk PbS is obtained, while adding the mercaptoethanol leads to production of nanoparticles. We found that the electronic absorption spectra as well as the particle sizes depend on the used capping agents. Two exitonic peaks with a large blue shift were observed when mercaptoethanol was used.

scholarly journals Adjusting inkjet printhead parameters to deposit drugs into micro-sized reservoirs

2016 ◽  
Vol 2 (1) ◽  
pp. 387-390 ◽  
Author(s):  
Robert Mau ◽  
Paul Oldorf ◽  
Rigo Peters ◽  
Hermann Seitz
Keyword(s):  
Drug Delivery Systems ◽  
Drug Carrier ◽  
Adverse Side Effects ◽  
Drug Deposition ◽  
Degradable Polymer ◽  
On Demand ◽  
Drop On Demand ◽  
Drug Concentrations ◽  
Inkjet Printhead ◽  
Drug Solution

AbstractDrug delivery systems (DDS) ensure that therapeutically effective drug concentrations are delivered locally to the target site. For that reason, it is common to coat implants with a degradable polymer which contains drugs. However, the use of polymers as a drug carrier has been associated with adverse side effects. For that reason, several technologies have been developed to design polymer-free DDS. In literature it has been shown that micro-sized reservoirs can be applied as drug reservoirs. Inkjet techniques are capable of depositing drugs into these reservoirs. In this study, two different geometries of micro-sized reservoirs have been laden with a drug (ASA) using a drop-on-demand inkjet printhead. Correlations between the characteristics of the drug solution, the operating parameters of the printhead and the geometric parameters of the reservoir are shown. It is indicated that wettability of the surface play a key role for drug deposition into micro-sized reservoirs.

Pseudo-Second-Order Kinetics for the Adsorption of Uranyl Ion onto Peat at Different pH Value

2010 ◽  
Vol 113-116 ◽  
pp. 33-36
Author(s):  
Zhi Rong Liu ◽  
Qin Qin Tao ◽  
Chuan Xi Wen
Keyword(s):  
Contact Time ◽  
Adsorption Process ◽  
Adsorption Equilibrium ◽  
Ph Value ◽  
Second Order ◽  
Uranyl Ions ◽  
Batch Tests ◽  
Effects Of Ph ◽  
Pseudo Second Order

Batch tests were used to investigate the effects of pH and contact time on the adsorption capability of peat. The results indicate that adsorption of uranyl ions on peat increase with increasing pH from 1 to 5. However it takes longer contact time to reach the adsorption equilibrium with increase of pH from 1 to 5. The adsorption process can be described by type 1 of the pseudo-second-order kinetics excellently.

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