scholarly journals Cutaneous manifestations in a patient with temporarily associated pediatric multisystemic inflammatory syndrome with COVID-19: case report

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Alessandra Oliveira ◽  
Kamilla Pádua ◽  
Maria Carolina Alves ◽  
Glaucia Silva ◽  
Fernando Paula ◽  
...  

OBJECTIVES: To describe the cutaneous manifestations presented by a patient with pediatric multisystemic inflammatory syndrome (MIS-C) temporarily associated with SARS-CoV-2. METHODS: Female patient, 10 years old, presenting arthralgia in the wrists and ankles, edema in hands and feet, persistent fever, appearance of diffuse, and itchy maculopapular rash associated with odynophagia and productive cough. Evolution of the rash to violaceous lesions on the face, trunk and limbs (upper and lower), in addition to the appearance of vesicles on the face, within 48 hours. CBC suggestive of an infectious condition, with CRP 307mg/L (insert reference value) and ESR 61mm. RT-PCR for SARS-CoV-2 positive. RESULTS: Diagnosis of pediatric multisystemic inflammatory syndrome temporarily associated with SARS-CoV2. Transferred to ICU for monitoring and intravenous human immunoglobulin initiated. Good evolution, with the disappearance of injuries and discharge with outpatient follow-up. CONCLUSION: MIS-C has several dermatological manifestations and pediatricians must be attentive to the diagnosis, not limited to a specific presentation. In this case report, the importance of referral to tertiary referral centers for better case management and timely recognition of the syndrome in these patients is emphasized.

2021 ◽  
Vol 22 (4) ◽  
pp. 199-203
Author(s):  
Jeenam Kim ◽  
Minkyoung Jeong ◽  
Dongkeun Jun ◽  
Myungchul Lee ◽  
Donghyeok Shin ◽  
...  

Primary cutaneous CD4+ small/medium T-cell lymphoproliferative disorder is a rare disease characterized by a single mass on the face or upper part of the trunk. It usually presents an asymptomatic and favorable progression, and its histopathologic findings include small and medium-sized lymphoid cells. The authors report a case of primary cutaneous CD4+ small/medium T-cell lymphoproliferative disorder on the forehead. A 51-year-old man presented with a protruding mass on his forehead that the patient had noted 1 month previously. Surgical excision and a permanent biopsy were performed under local anesthesia. Based on the biopsy results, the mass was diagnosed as a primary cutaneous CD4+ small/medium T-cell lymphoproliferative disorder. There was no evidence of recurrence at a 15-month follow-up visit.


Revista CEFAC ◽  
2020 ◽  
Vol 22 (4) ◽  
Author(s):  
Geciane Xavier Torres ◽  
Emerson de Santana Santos ◽  
Carla Patrícia Hernandez Alves Ribeiro César ◽  
Roxane de Alencar Irineu ◽  
Isabel Ribeiro Rocha Dias ◽  
...  

ABSTRACT Noonan syndrome is an autosomal dominant genetic disease with different manifestations, including Speech, Language and Hearing Sciences ones. The authors describe the orofacial and myofunctional manifestations of an adolescent diagnosed with Noonan syndrome, by consulting the Speech, Language and Hearing Sciences record of a 17-year-old male patient, who underwent screening and speech therapy evaluation with a confirmed genetic diagnosis of Noonan syndrome. The results were qualitatively analyzed. The patient had a long facial type, with a disproportion between the lower and middle thirds of the face, ogival palate, and Mallampati class IV. A deficit in mobility and sensitivity of phonoarticulatory organs was also identified, absence of pathological oral and gag reflexes, decreased lip tone and tongue tension, increased speed chewing and inefficient grinding, functional swallowing for assessed consistencies, mild verbal and nonverbal apraxia, and moderate dysarthria. The results confirmed the presence of alterations in the speech-language organs, proving the relevance of the Speech, Language and Hearing Sciences evaluation in Noonan Syndrome, to allow adequate follow-up and treatment.


2016 ◽  
Vol 48 ◽  
pp. e195-e196
Author(s):  
E. Peruzzi ◽  
F. Piersimoni ◽  
A. Carella ◽  
A. Giacchetti ◽  
G. Ricotti ◽  
...  

Author(s):  
Tales Gabriel de Souza Cerioni ◽  
Rafael Jorge Ruman ◽  
Willian Jamil Hassanieh ◽  
Gustavo Rodrigues Manrique ◽  
Wladimir Gushiken de Campos ◽  
...  

Facial fractures caused by gunshots are a major challenge for oral and maxillofacial surgeons. Underdeveloped countries present a higher rate of homicides committed by gunshots than developed countries. This case report presents a 25 year-old male victim of a gunshot wound to the mandible, evolving into a complex fracture. The fracture was treated using rigid internal fixation. After 18 months of follow-up, the patient presents good facial appearance and masticatory activity. The gunshot caused the permanent paralysis of the right mandibular branch of the facial nerve. We managed to preserve the involved teeth and mandibular integrity, with complete bone healing. Despite the late infection following plate fixation, healing occurred without further complications, indicating that blood supply was maintained.


2020 ◽  
pp. 1-2
Author(s):  
Hicham Ngham ◽  
◽  
Lyoubi Hicham ◽  

Primary non-Hodgkin’s lymphoma (NHL) of Paranasal sinus is a rare entity with special characteristics; their locations in the air spaces of the face coming in second row. The prognosis depends on tumor stage and extension into the paranasal sinuses We related the case of a primitive NHL located in the maxillary sinus in a patient of 50 years, invading the entire homolateral nasal cavity. The histopathologic interpretation was B cell lymphoma; the patient received 5 adjuvant chemotherapy treatments according to the CHOP protocol, followed by locoregional external radiotherapy and the evolution was favorable after eighteen months follow-up


F1000Research ◽  
2019 ◽  
Vol 8 ◽  
pp. 1798
Author(s):  
Nasim Niknezhad ◽  
Farahnaz Bidari-Zerehpoosh ◽  
Nakisa Niknejad ◽  
Nikoo Mozafari

In this report, we described a 58-year-old man, presenting with multiple plaques and nodules over the nose and forehead resembling sarcoidosis or lepromatous leprosy. The histologic study revealed deposition of the mass of amorphous, eosinophilic-cleaved, colloid materials in the papillary dermis and deep dermis. The periodic acid-Schiff (PAS) stain was positive, whereas the Congo red stain was negative.  Based on the clinical and pathologic findings, the patient was diagnosed with nodular colloid degeneration(NCD). To treat the patient, lesions were flattened using a Co2 laser. The patient did not return for follow-up.  NCD is a rare disease,  with only 12 cases having been previously reported. Here, we present a case of NCD that occurred on the face and discuss the topic of how to discriminate between NCD and other similar entities, emphasizing that nodular colloid degeneration should be  considered  in the differential diagnosis of asymptomatic facial plaques and nodules.


2020 ◽  
Vol 4 (3) ◽  
pp. 349-351 ◽  
Author(s):  
Randall Beaupre II ◽  
Cody Petrie ◽  
Alexander Toledo

Introduction: The coronavirus disease of 2019 (COVID-19) caused by the novel severe acute respiratory syndrome coronavirus 2 is a global pandemic that expresses itself with a wide variety of presenting symptoms in patients. There is a paucity of literature describing the dermatologic manifestations of the virus, particularly in the United States. Case Report: Here we present a case of COVID-19 that manifested with a purpuric rash on the lower extremities and a maculopapular eruption on the abdomen in a patient in acute diabetic ketoacidosis and normal platelet count. Discussion: The reported presenting symptoms of patients with COVID-19 vary greatly. This is the first documented case of COVID-19 presenting with mixed cutaneous manifestations of a purpuric as well as maculopapular rash. Conclusion: The cutaneous lesions associated with the COVID-19 infection may mimic or appear similar to other well-known conditions. We illustrate a case of COVID-19 infection presenting with purpuric rash on the lower extremities and a maculopapular rash on the abdomen.


2018 ◽  
Vol 31 (04) ◽  
pp. 248-253 ◽  
Author(s):  
Shamsur Rahman ◽  
Joy Dey

AbstractPsoriasis on the hands and feet often appears on the palms and soles that are called palmopantar psoriasis. Treatment in modern medicine uses local and systematic antibiotics. Homoeopathy has mentioned medicines for plantar psoriasis. A case reported was a female of 7 years of age suffering from symptoms of itching, red scaly plaques, eruption with very offensive odour which aggravates at night, burning in both hands and feet which aggravates at night, weight-bearing area of the sole had painful cracking, scaling, swelling and blister. Also, she had burning on both hands and feet which aggravates at night and was diagnosed as plantar psoriasis. The homoeopathic medicine Syphilinum 1000C was prescribed on the basis of totality of symptoms, Materia Medica and miasm. Plantar psoriasis was reduced considerably within 10 days, and it disappeared completely in 2 months 20 days. No recurrence of plantar psoriasis was observed for another 5 years as well. Photographs during follow-up visits have provided as documentary evidence about the effectiveness of homoeopathic medicine Syphilinum 1000C in plantar psoriasis.


2014 ◽  
Vol 46 ◽  
pp. S69-S70
Author(s):  
E. Peruzzi ◽  
F. Piersimoni ◽  
A. Giacchetti ◽  
G. Ricotti ◽  
M. Lucioni ◽  
...  

Author(s):  
Ouajid Bakkali ◽  
S. Benchekroun ◽  
A. Asermouh ◽  
F. Benbrahim ◽  
N. Elhafidi ◽  
...  

Rat-bite fever (RBF) is a systemic infectious disease. It is due to Streptobacillus moniliformis, a commensal bacterium of the nasopharyngeal mucosa of small rodents, in particular rats. This anthropozoonosis is rare in urban areas. The first clinical sign of infection is a fever, followed by polyarthritis and a rash. It can only start with skin signs, as in our observation. We report the case of a 41-day-old female infant who was the victim of a rat bite at one month of life in the upper nasal and labial areas. A rabies vaccine with local care has been made. The clinical course at 3 days after the bite was marked by a non-pruritic papulopustular rash, the vesiculo-bullous lesions in the bilateral and symmetrical legs evolved into inflammatory ulcerative necrotizing lesions in a geographic map of the lower 1/3 of the lower limbs with gangrenous lesions in the toes, an erythematous base on the face, hands and feet and discreet oral erosions, associated with generalized purpuric spots and fevers at 40°C. The biological assessment was carried out objectifying an inflammatory syndrome made of a leukocytosis at 26770/mm3, with neutrophils at 10842/mm3, CRP = 215 mg/L. The diagnosis of RBF was made by the isolation of a Gram-negative bacillus in a blood culture. The final identification of the germ was carried out by molecular biology (PCR of 16S rRNA). The lumbar puncture was negative and the cardiac ultrasound was without abnormality. Arterial and venous Doppler ultrasound of the lower limbs was normal. The diagnosis of rat bite fever having been retained. The infant was put on cefpodoxime IV for 3 weeks and metronidazole IV for 10 days. The clinical course at 3 months later, spontaneous amputation of gangrenous toes with residual skin scars was noted.


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