scholarly journals PROLAB SOFTWARE FOR DATA EVALUATION OF INTERLABORATORY STUDIES

2017 ◽  
Vol 44 (3) ◽  
pp. 23 ◽  
Author(s):  
Jelena M Bebić ◽  
Luka S Gažević ◽  
Christian Bläul
Keyword(s):  
Software Package ◽  
Certified Reference Materials ◽  
Precious Metals ◽  
Large Data ◽  
International Standards ◽  
Interlaboratory Comparisons ◽  
Data Set ◽  
Interlaboratory Studies ◽  
Iso 13528 ◽  
The Republic

Interlaboratory studies represent a form of external quality control for laboratories. International standards that are used for interlaboratory comparisons, ISO 17043, ISO 13528, ISO 5725, define ways of organisation of comparisons and data treatment of participating laboratories’ results. Intercomparison results can be exploited, apart from the main goal for laboratory performance evaluation, also for method validation and production of Certified Reference Materials. PROLab is a comprehensive, globaly accepted and standardized software package for evaluating interlaboratory studies. It provides large data set structures, graphical andcomputational methods for optimal use of the data. Directorate of Measures and Precious Metals has purchased and installed software package PROLab Plus, licenced as the only one in the Republic of Serbia. As such, it will be available to all interested organisers of interlaboratory comparisons, in our country.

scholarly journals A new notion of transitive relative return rate and its applications using stochastic differential equations

2019 ◽  
Vol 23 (Suppl. 1) ◽  
pp. 113-120
Author(s):  
Burhaneddin Izgi
Keyword(s):  
Differential Equations ◽  
Stochastic Differential Equations ◽  
Large Data ◽  
Real Data ◽  
Return Rate ◽  
Data Set ◽  
Intel Corporation ◽  
Milstein Method ◽  
The Republic ◽  
Relative Return

We introduce a new notion of transitive relative return rate and present its applications based on the stochastic differential equations. First, we define the notion of a relative return rate and show how to construct the transitive relative return rate (TRRR) on it. Then, we state some propositions and theorems about relative return rate and TRRR and prove them. Moreover, we exhibit the theoretical framework of the generalization of TRRR for 3 n ? cases and prove it, as well. Furthermore, we illustrate our approach with real data applications of daily relative return rates for Borsa Istanbul-30 (BIST-30) and Intel Corporation indexes with respect to daily interest rate of Central Bank of the Republic of Turkey between June 18, 2003 and June 17, 2013. For this purpose, we perform simulations via Milstein method. We succeed to present usefulness of the relative return rate for the relevant real large data set using the numerical solution of the stochastic differential equations. The simulation results show that the proposed closely approximates the real data

Some statistical and CI models to predict chaotic high-frequency financial data

2020 ◽  
Vol 39 (5) ◽  
pp. 6419-6430
Author(s):  
Dusan Marcek
Keyword(s):  
Time Series Data ◽  
Moving Average ◽  
Methodological Approach ◽  
Back Propagation ◽  
Large Data ◽  
Series Data ◽  
Data Set ◽  
Training Time ◽  
Optimal Population ◽  
Forecast Time

To forecast time series data, two methodological frameworks of statistical and computational intelligence modelling are considered. The statistical methodological approach is based on the theory of invertible ARIMA (Auto-Regressive Integrated Moving Average) models with Maximum Likelihood (ML) estimating method. As a competitive tool to statistical forecasting models, we use the popular classic neural network (NN) of perceptron type. To train NN, the Back-Propagation (BP) algorithm and heuristics like genetic and micro-genetic algorithm (GA and MGA) are implemented on the large data set. A comparative analysis of selected learning methods is performed and evaluated. From performed experiments we find that the optimal population size will likely be 20 with the lowest training time from all NN trained by the evolutionary algorithms, while the prediction accuracy level is lesser, but still acceptable by managers.

The Determinants of Capital Adequacy Ratio: The Case of the Vietnamese Banking System in the Period 2011-2015

2017 ◽  
Vol 33 (2) ◽  
Author(s):  
Ngoc Anh Nguyen
Keyword(s):  
Banking System ◽  
Precious Metals ◽  
Capital Adequacy ◽  
The Other ◽  
Total Asset ◽  
Data Set ◽  
Hand Size ◽  
Net Interest Margin ◽  
Capital Adequacy Ratio ◽  
Positive Effect

The analysis of a data set of observation for Vietnamese banks in period from 2011 - 2015 shows how Capital Adequacy Ratio (CAR) is influenced by selected factors: asset of the bank SIZE, loans in total asset LOA, leverage LEV, net interest margin NIM, loans lost reserve LLR, Cash and Precious Metals in total asset LIQ. Results indicate based on data that NIM, LIQ have significant effect on CAR. On the other hand, SIZE and LEV do not appear to have significant effect on CAR. Variables NIM, LIQ have positive effect on CAR, while variables LLR and LOA are negatively related with CAR.

CRIMINAL LAW IN PROTECTION OF HEALTH FROM THE ABUSE OF DRUGS IN SERBIA

2018 ◽  
Vol 28 (6) ◽  
pp. 1939-1946
Author(s):  
Miodrag Simović ◽  
Dragan Jovašević ◽  
Marina M. Simović
Keyword(s):  
United Nations ◽  
Criminal Law ◽  
International Standards ◽  
Individual State ◽  
Criminal Sanctions ◽  
Criminal Offenses ◽  
Different Types ◽  
The Republic ◽  
To Come ◽  
Practical Sense

Based on international standards adopted within the framework and under the Organisation of the United Nations, all national legislations recognise several different types and forms of criminal acts regarding misuse of narcotics. It is the matter of various activities of unauthorized production, traffic and other forms of inciting or enabling others to come into possession of narcotics for immediate use, which seriously endangers the health and life.Depending on the needs of each individual state, the distinction is made between the offenses, for the perpetrators are given different types and measures of penalties and other criminal sanctions. A similar situation exists in the Republic of Serbia.The paper analyzes the system of criminal offenses in various types and forms of manifestation in the theoretical and practical sense for whose offenders that are prescribed serious criminal sanctions.

In silico Prediction of Inhibitory Constant of Thrombin Inhibitors Using Machine Learning

2019 ◽  
Vol 21 (9) ◽  
pp. 662-669 ◽  
Author(s):  
Junnan Zhao ◽  
Lu Zhu ◽  
Weineng Zhou ◽  
Lingfeng Yin ◽  
Yuchen Wang ◽  
...  
Keyword(s):  
Machine Learning ◽  
Prediction Models ◽  
Regression Tree ◽  
Large Data ◽  
Thrombin Inhibitors ◽  
Coagulation Cascade ◽  
Gradient Boosting ◽  
Support Vector ◽  
Data Set ◽  
Descriptor Selection

Background: Thrombin is the central protease of the vertebrate blood coagulation cascade, which is closely related to cardiovascular diseases. The inhibitory constant Ki is the most significant property of thrombin inhibitors. Method: This study was carried out to predict Ki values of thrombin inhibitors based on a large data set by using machine learning methods. Taking advantage of finding non-intuitive regularities on high-dimensional datasets, machine learning can be used to build effective predictive models. A total of 6554 descriptors for each compound were collected and an efficient descriptor selection method was chosen to find the appropriate descriptors. Four different methods including multiple linear regression (MLR), K Nearest Neighbors (KNN), Gradient Boosting Regression Tree (GBRT) and Support Vector Machine (SVM) were implemented to build prediction models with these selected descriptors. Results: The SVM model was the best one among these methods with R2=0.84, MSE=0.55 for the training set and R2=0.83, MSE=0.56 for the test set. Several validation methods such as yrandomization test and applicability domain evaluation, were adopted to assess the robustness and generalization ability of the model. The final model shows excellent stability and predictive ability and can be employed for rapid estimation of the inhibitory constant, which is full of help for designing novel thrombin inhibitors.

scholarly journals Correlation between the structure and skin permeability of compounds

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Ruolan Zeng ◽  
Jiyong Deng ◽  
Limin Dang ◽  
Xinliang Yu
Keyword(s):  
Large Data ◽  
Qsar Model ◽  
Coefficient Of Determination ◽  
Support Vector ◽  
Skin Permeability ◽  
Data Set ◽  
Test Set ◽  
Svm Algorithm ◽  
Svm Model ◽  
Toxicity Relationship

AbstractA three-descriptor quantitative structure–activity/toxicity relationship (QSAR/QSTR) model was developed for the skin permeability of a sufficiently large data set consisting of 274 compounds, by applying support vector machine (SVM) together with genetic algorithm. The optimal SVM model possesses the coefficient of determination R2 of 0.946 and root mean square (rms) error of 0.253 for the training set of 139 compounds; and a R2 of 0.872 and rms of 0.302 for the test set of 135 compounds. Compared with other models reported in the literature, our SVM model shows better statistical performance in a model that deals with more samples in the test set. Therefore, applying a SVM algorithm to develop a nonlinear QSAR model for skin permeability was achieved.

scholarly journals Galaxy spin direction distribution in HST and SDSS show similar large-scale asymmetry

2020 ◽  
Vol 37 ◽  
Author(s):  
Lior Shamir
Keyword(s):  
Large Scale ◽  
Spiral Galaxies ◽  
Hubble Space Telescope ◽  
Gravitational Interaction ◽  
Large Data ◽  
Sloan Digital Sky Survey ◽  
Data Sets ◽  
Dipole Axis ◽  
Data Set ◽  
The Asymmetry

Abstract Several recent observations using large data sets of galaxies showed non-random distribution of the spin directions of spiral galaxies, even when the galaxies are too far from each other to have gravitational interaction. Here, a data set of $\sim8.7\cdot10^3$ spiral galaxies imaged by Hubble Space Telescope (HST) is used to test and profile a possible asymmetry between galaxy spin directions. The asymmetry between galaxies with opposite spin directions is compared to the asymmetry of galaxies from the Sloan Digital Sky Survey. The two data sets contain different galaxies at different redshift ranges, and each data set was annotated using a different annotation method. The results show that both data sets show a similar asymmetry in the COSMOS field, which is covered by both telescopes. Fitting the asymmetry of the galaxies to cosine dependence shows a dipole axis with probabilities of $\sim2.8\sigma$ and $\sim7.38\sigma$ in HST and SDSS, respectively. The most likely dipole axis identified in the HST galaxies is at $(\alpha=78^{\rm o},\delta=47^{\rm o})$ and is well within the $1\sigma$ error range compared to the location of the most likely dipole axis in the SDSS galaxies with $z>0.15$ , identified at $(\alpha=71^{\rm o},\delta=61^{\rm o})$ .

scholarly journals The Complete DNA Sequence of the Mitochondrial Genome of a “Living Fossil,” the Coelacanth (Latimeria chalumnae)

Genetics ◽  
1997 ◽  
Vol 146 (3) ◽  
pp. 995-1010 ◽  
Author(s):  
Rafael Zardoya ◽  
Axel Meyer
Keyword(s):  
Mitochondrial Genome ◽  
Tandem Repeats ◽  
Phylogenetic Analyses ◽  
Large Data ◽  
Molecular Data ◽  
Phylogenetic Position ◽  
Data Set ◽  
Living Fossil ◽  
Latimeria Chalumnae ◽  
Relationship Of

The complete nucleotide sequence of the 16,407-bp mitochondrial genome of the coelacanth (Latimeria chalumnae) was determined. The coelacanth mitochondrial genome order is identical to the consensus vertebrate gene order which is also found in all ray-finned fishes, the lungfish, and most tetrapods. Base composition and codon usage also conform to typical vertebrate patterns. The entire mitochondrial genome was PCR-amplified with 24 sets of primers that are expected to amplify homologous regions in other related vertebrate species. Analyses of the control region of the coelacanth mitochondrial genome revealed the existence of four 22-bp tandem repeats close to its 3′ end. The phylogenetic analyses of a large data set combining genes coding for rRNAs, tRNA, and proteins (16,140 characters) confirmed the phylogenetic position of the coelacanth as a lobe-finned fish; it is more closely related to tetrapods than to ray-finned fishes. However, different phylogenetic methods applied to this largest available molecular data set were unable to resolve unambiguously the relationship of the coelacanth to the two other groups of extant lobe-finned fishes, the lungfishes and the tetrapods. Maximum parsimony favored a lungfish/coelacanth or a lungfish/tetrapod sistergroup relationship depending on which transversion:transition weighting is assumed. Neighbor-joining and maximum likelihood supported a lungfish/tetrapod sistergroup relationship.

Climatology of nutrient distributions in the South China Sea based on a large data set derived from a new algorithm

2021 ◽  
pp. 102586
Author(s):  
Chuanjun Du ◽  
Ruoying He ◽  
Zhiyu Liu ◽  
Tao Huang ◽  
Lifang Wang ◽  
...  
Keyword(s):  
South China Sea ◽  
South China ◽  
Large Data ◽  
The South China Sea ◽  
The South ◽  
Data Set ◽  
China Sea ◽  
Large Data Set
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