scholarly journals Assessment of Body Mass (Weight Loss/Gain) in a 14 Day Clinical and Parasitological Responses to Supervised Antimalarial Drug Combination Therapies in Abakaliki, Ebonyi State

2021 ◽  
Vol 3 (1) ◽  
pp. 20-25
Author(s):  
I.M. Ikeh ◽  
◽  
O.O. Odikamnoro ◽  
V.O. Okonkwo ◽  
◽  
...  

Malaria has considerable potential for adversely influencing host nutrition. It can restrict food intake through anorexia while causing vomiting or diarrhea, it may interfere with the absorption of ingested food. This survey was however conducted to ascertain the impact of the Plasmodium falciparum malaria attack on the weight potentials of the sufferers treated with Diaminopyrimidines (Pyrimethamine) and Sulphonamides (Sulfadoxine) Out of 243 patients studied in Abakaliki, the age groups 10-19 (48.6%), 20-29 (30.0%), 30-39 (12.8%), 40-49 (5.8%), and 50-59 (2.9%) showed average weight loss/gain of ± 1.4, ±0.3, ± 0.6, and± 0.2 respectively for both males, and females. The corresponding weight loss/gain between D0-D7 showed 10 ≤ 20: D0-D2 (-0.1), D2-D7 (+0.7), 21≤ 30: D0-D2 (- 0.3), D2-D7 (+ 0.2); 31 ≤ 40: D0-D2 (0.0), D2-D7 (+0.2);41 ≤ 50: D0-D2 (- 0.1), D2-D7 (- 0.1),51≤ 60: D0-D2 (0.0), D2-D7 (+ 0.2).The result of increased catabolism of proteins and associated weight loss in severe malaria attack should be regained by nutritional sufficiency.

2021 ◽  
Vol 8 ◽  
Author(s):  
Taha Anbara

Introduction: Laparoscopic sleeve gastrectomy is a primary treatment of obesity among older adults and its satisfactory outcomes would be the main reason behind the popularity of this procedure. We aim to evaluate the impact of age on excess weight loss in adult morbidly obese subjects older than 60 years old following LSG.Methods: In this retrospective survey, 3,072 subjects were included in the study that underwent LSG in Erfan Hospital. Screening follow-up period was 12 months. The level of statistical significance was set at P < 0.05. We hired comorbid conditions to avoid bias results including hypertension, diabetes mellitus and dyslipidemia. Results: Of 3072 patients, 1879 cases were females (61.2%) and 1193 subjects were males (38.8 %). Mean %EBMIL of the group 12 months after surgery was 78.9 %. In younger than 60 years old group, mean %EBMIL 12 months postoperative 83 % and patients  over 60 years demonstrated mean %EBMIL 74.9 %. There was an obvious difference among age groups in presence of diabetes mellitus and hypertension in the older group which was more frequent. Conclusion: To sum up, laparoscopic sleeve gastrectomy is safe procedure for older groups. Albeit, %EBMIL was significantly lower in older group compared to younger subjects, but resolution in comorbidities was satisfactory.


1987 ◽  
Vol 151 (6) ◽  
pp. 813-817 ◽  
Author(s):  
Alex B. Christie ◽  
Eric R. M. Wood

The impact of a 16% increase between censuses in the population aged 65 and over, on a psychogeriatric department whose bed complement remained static between 1974 and 1984, has been studied. Demand for service, as measured by new referrals, rose by 150%, while admissions fell by 14%. The increase in new referrals was uniform across the diagnostic spectrum, but the fall in admissions was not. Functional admissions fell in all age-groups except that of women of 85 and over, while organic-case admissions other than for cases of dementia virtually collapsed. Overall admissions for dementia rose to the predicted level, but the distribution of the increase was irregular and unexpected. Admissions of males and females aged 65–74 and females of 85 and over fell relatively and absolutely, while those of women aged 75–84 and men of 85 and over were little changed. Only admissions of men aged 75–84 alone increased in real terms.


2020 ◽  
Author(s):  
Denny John ◽  
Narassima MS ◽  
Jaideep C Menon ◽  
Guru Rajesh Jammy

Abstract Background: The COVID-19 pandemic has had a huge impact on the global economy and stressed the health care systems worldwide. Measuring the burden of disease on health and economy is essential for system preparedness by way of allocation of funds and human resources.Methods: The present study estimates Disability-Adjusted Life Years (DALYs), Years of Potential Productive Life Lost (YPPLL) and Cost of Productivity Lost (CPL) due to premature mortality and absenteeism, secondary to COVID-19 in Kerala state, India. The impact of disease on various age-gender cohorts has been analyzed. Sensitivity Analysis has been conducted by adjusting six variables with a total of 21 scenarios. Results: Severity of infection and mortality were higher among older sub-group of patients, and male were more susceptible than female in most of the age groups. DALY for the baseline scenario was 15,924.24 and 8,669.32 for males and females respectively. The CPL due to premature mortality was 26,80,36,179 and 42,510,946 for males and females respectively. Conclusion: People aged more than 50 were disproportionately affected by the disease, with presence of comorbidities further raising vulnerability.


2017 ◽  
Vol 203 (4) ◽  
pp. 258-266 ◽  
Author(s):  
Aarón Leonardo Pogacnik Murillo ◽  
Felix Eckstein ◽  
Wolfgang Wirth ◽  
Daniel Beavers ◽  
Richard F. Loeser ◽  
...  

Objectives: The infrapatellar fat pad (IPFP) represents intra-articular adipose tissue that may contribute to intra-articular inflammation and pain by secretion of proinflammatory cytokines. Here we examined the impact of weight loss by diet and/or exercise interventions on the IPFP volume. Methods: Intensive Diet and Exercise for Arthritis (IDEA) was a single-blinded, single-center, 18-month, prospective, randomized controlled trial that enrolled 454 overweight and obese older adults with knee pain and radiographic osteoarthritis. Participants were randomized to 1 of 3 groups: exercise-only control (E), diet-induced weight loss (D), and diet-induced weight loss + exercise (D+E). In a subsample (n = 106; E: n = 36, D: n = 35, and D+E: n = 35), magnetic resonance images were acquired at baseline and at the 18-month follow-up, from which we analyzed IPFP volume, surface areas, and thickness in this secondary analysis. Results: The average weight loss amounted to 1.0% in the E group, 10.5% in the D group, and 13.0% in the D+E group. A significant (p < 0.01) reduction in IPFP volume was observed in the E (2.1%), D (4.0%), and D+E (5.2%) groups. The IPFP volume loss in the D+E group was significantly greater than that in the E group (p < 0.05) when not adjusting for parallel comparisons. Across intervention groups, there were significant correlations between IPFP volume change, individual weight loss (r = 0.40), and change in total body fat mass (dual-energy X-ray absorptiometry; r = 0.44, n = 88) and in subcutaneous thigh fat area (computed tomography; r = 0.32, n = 82). Conclusions: As a potential link between obesity and knee osteoarthritis, the IPFP was sensitive to intervention by diet and/or exercise, and its reduction was correlated with changes in weight and body fat.


Obesity Facts ◽  
2020 ◽  
pp. 1-13
Author(s):  
Ji-Bin Li ◽  
Zhi-Yu Qiu ◽  
Zhen Liu ◽  
Qian Zhou ◽  
Li-Fen Feng ◽  
...  

<b><i>Objectives:</i></b> The impact of heterogeneity on gender difference for achieving clinically meaningful weight loss (cmWL) remains unclear. Here, we explored the potential gender differences in factors associated with cmWL. <b><i>Methods:</i></b> A total of 60,668 participants with body mass index (BMI) ≥25 kg/m<sup>2</sup> at study entry and available BMI values at follow-up were included in this study. cmWL was defined as a weight loss of ≥5% from the study entry to follow-up. The associations of social-demographic factors, personal history of chronic diseases, lifestyle behaviors, and history of BMI with cmWL were evaluated using logistic regression models. <b><i>Results:</i></b> During a median follow-up of 9.13 years, 26.6% of the participants had a cmWL (30.8% for females vs. 23.1% in males; <i>p</i> &#x3c; 0.001). Participants with older age, obesity at study entry, being more physical activity compared to 10 years ago, being relapsed smokers or consistent current smokers, having a history of chronic diseases (i.e., diabetes, osteoporosis, and stroke), cancer diagnosis during the study period, and more than 10-year follow-up were more likely to achieve cmWL in both males and females (all <i>p</i> &#x3c; 0.05). The new smoking quitters and participants with less active in physical activity compared to 10 years ago were less likely to achieve cmWL in both males and females (all <i>p</i> &#x3c; 0.05). Specifically, males with a history of emphysema were more likely to reach cmWL, and for females, those being overweight at 20 years old and current drinkers were more likely to reach cmWL (<i>p</i> &#x3c; 0.05). Sensitivity analyses demonstrated similar results. <b><i>Conclusion:</i></b> Age, BMI status, physical activity, smoking status, family income, and health status were independent factors in males and females for weight management. However, further well-designed prospective studies are warranted to confirm our findings.


2020 ◽  
Vol 7 (Supplement_1) ◽  
pp. S338-S338
Author(s):  
Roberta L DeBiasi ◽  
Xiaoyan Song ◽  
Emily Ansusinha ◽  
Karen L Smith ◽  
Michael Bell ◽  
...  

Abstract Background Children and young adults were initially reported as largely spared from severe complications of SARS-CoV-2 infection, but the impact to this population has been significant. Methods This observational retrospective cohort study includes 420 symptomatic children and young adults with lab confirmed SARS-CoV-2 infection treated between March 15 and June 16, 2020 at Children’s National Hospital in Washington DC. We identified and compared cohorts of non-hospitalized (N=324) and hospitalized (N=96) patients, including non-critically ill (N=64) and critically ill hospitalized (N=32) patients. Clinical and demographic data were extracted from medical records Results Of 420 SARS-CoV-2-infected symptomatic patients, 23% required hospitalization, of which 67% were non-critically ill and 33% were critically ill. All age groups were represented in the symptomatic cohort, with a median age of 8.6 years. Patients &gt; 15 years of age represented 44% of critical care admissions. Males and females were equally represented in all cohorts. Underlying medical conditions were present in 36%, but more common in hospitalized (59 %) and critically ill (66 %) patients. The most frequent underlying diagnosis overall was asthma (16 %), but also included neurologic (6 %), diabetes (3 %), obesity (3 %), cardiac (3 %), hematologic (3 %) and oncologic (1 %) conditions. The majority (66 %) of SARS-CoV-2 infected patients presented with respiratory symptoms with or without fever. Other symptoms were also present, including diarrhea/vomiting (21 %), myalgia (11 %), chest pain (8 %) and loss of sense of smell or taste (7%). Hospitalized patients required varying levels of respiratory support, including mechanical ventilation, BiPAP, RAM cannula and HFNC. Additional presentations included diabetic hyperglycemia, sickle cell vaso-occlusive crisis, vascular complications, and multisystem inflammation. Treatment included remdesivir, convalescent plasma, tocilizumab and other therapies. Conclusion Although children/young adults have been less affected than elderly adults, the impact of SARS-CoV2 on this population has been significant in Washington DC and informs other regions anticipating their surge. Disclosures Andrea Hahn, MD, MS, Johnson and Johnson (Consultant)


2020 ◽  
Vol 4 (Supplement_1) ◽  
pp. 904-904
Author(s):  
Jenna Napoleone ◽  
Elsa Strotmeyer ◽  
Rachel Miller ◽  
Susan Devaraj ◽  
Bonny Rockette-Wagner ◽  
...  

Abstract The Diabetes Prevention Program (DPP) lifestyle intervention demonstrated that meeting the weight loss (WL) and activity goals prevents/delays type 2 diabetes. Older DPP participants, 60-85 years, reduced the risk of developing diabetes by 71% versus 58% in those &lt;60 years. Currently, community translated DPP-based lifestyle interventions including Group Lifestyle Balance (DPP-GLB), are reimbursed by Medicare for overweight/obese older adults with prediabetes. This effort examined the impact of age group (60-65: reference, 66-70, ≥71 years) on both DPP-GLB maintenance session attendance (months 7-12) and achieving the 5% WL goals at 6- and 12-months. Data were combined from two identical 12-month DPP-GLB intervention trials involving overweight/obese adults with prediabetes and/or metabolic syndrome. Participants ≥60 years attending ≥4 sessions (months 0-6), with complete data on session attendance and WL were included (n=145; age=68.7 + 5.8 years, range 60-88; 79% women). Participants aged 66-70 years (N=46) were more likely to meet the 6-month 5% WL goal (67.4%) vs. 60-65 years (N=51; 45.1%; p=0.03). Participants aged 66-70 (69.6%) and ≥71 years (N=48; 60.4%) were more likely to meet the 12-month WL goal vs. 60-65 years (35.3%; 66-70: p=0.0007; ≥71: p=0.01). Maintenance attendance did not vary by age group with approximately 30% of each group attending ≥4 of 6 maintenance sessions (p=0.55). In conclusion, adults 66+ vs. 60-65 years more successfully met the clinically meaningful 5% WL goals at 6 and 12 months. With nationwide implementation of community-based “real-world” DPP-GLB lifestyle interventions, better understanding of program success across older adult age groups will enhance program reach and effectiveness.


2020 ◽  
Vol 13 (Suppl_1) ◽  
Author(s):  
Alexandre Shehata ◽  
Ishan Patel ◽  
Isha Samreen ◽  
Swaiman Singh ◽  
Sergio Waxman ◽  
...  

Introduction: The morbidity and mortality associated with obesity (BMI >30 kg/m2) has been known to medical science for more than 2000 years. 1 Obesity is increasing in prevalence in adults, adolescents, and children and is considered a global epidemic. The age-adjusted overall prevalence of obesity in the United States increased progressively from 22.9 to 30.5 to 39.6 percent from the year 2007 to 2016. 2 Purpose: To Assess if filling out a survey on obesity has any impact on a patient’s behavior and self-awareness in an outpatient setting. Methods: In an urban outpatient setting, 350 individuals aged 18 and above, suffering from obesity (defined as BMI >30/m2) were asked to fill-out a survey. The survey included basic demographic information, weight, employment status, exercise frequency, eating habits, and questions about self-perception. Patients filled out an identical follow-up survey 2-3 months later. We measured the changes in responses between the pre- and the post- survey. Results: Of the 350 original respondents, 103 patients followed up with the post-survey. 68.9% were women, 73.2% were African-American, and 62.3% were unemployed. 46.4% of patients felt neutral, or content about their current weight. 37.7% of patients reported never exercising in the pre-survey vs. 16.8% in the post-survey (20.9% improvement), while 25.3% of patients reported exercising 2-3 times per week in the pre-survey vs. 36.4% in the post-survey (11.1% improvement). 61% of patients had lost weight (average weight loss of 6.75lbs), 19% of patients had gained weight (average weight gain 4.55 lbs.) and 20% had maintained the same weight. We recorded a net weight loss of 2.2 lbs. Conclusion: In our pilot study, we found that the act of filling out a survey on obesity may have a positive impact on the behavior and self-awareness of patients with BMI > 30kg/m2. Larger sample sizes would be beneficial in order to further establish the impact of such intervention. 1. Bray GA. The Battle of the Bulge: A History of Obesity Research, Dorrance, Pittsburgh 2007. 2. Hales CM, Fryar CD, Carroll MD, Freedman DS, Ogden CL. Trends in Obesity and Severe Obesity Prevalence in US Youth and Adults by Sex and Age, 2007-2008 to 2015-2016. JAMA. 2018;319(16):1723.


Author(s):  
L Poudel ◽  
B Thapa ◽  
BP Shrestha ◽  
NK Shrestha

Hydropower is considered as one of the most economical and stable base energy source compared with other sources of energy of Nepal. Researches coherent to this field are not new but yet it is not sufficient, lots of tiles have to be kept for better understanding of hydropower effecting elements. Sand is the most affecting element that damages the turbine blades, so research on relation of sand and turbine is most. This research is done to find out the impact of sediment on turbine material. Modi River sediment at eight different stations has been taken as sample and its erosion rate in turbine blade sample specimen has been accounted in this study. Rotating disc apparatus has been utilized to find out the total impact of sand on turbine material. Four same kind of test turbine material is used on single rotating disc all at a time at same condition to define sand impact. Thirty gram (gm) of sediment mixed with three liters of water is used to strike sample pieces for five minutes. Two different tests of sediment samples of 8 different locations were studied. After all the test it is observed that the first test sand sample of location 1 and turbine material 1 has the highest impact with a weight loss of 7.764 mg and least impact in sand sample location 1 and sand sample 3 with a weight loss of 3.5 mg. Average weight loss of turbine material in first location is 5.929 mg which is the greatest impact and 4.0083 at eight locations which is the least. Relating to turbine material first rotating disc turbine specimen P0A has been affected highly with weight loss of 9.289 mg and less eroded on P5A rotating turbine specimen with weight loss of 1.2 mg. DOI: http://dx.doi.org/10.3126/kuset.v8i1.6047 KUSET 2012; 8(1): 88-96


2017 ◽  
Vol 7 (4) ◽  
pp. 56
Author(s):  
Ala'a Mohammad Al-Smadi

This study aims at investigating the WhatsApp statuses as used by Jordanian people from a sociolinguistic point of view. It attempts to examine the use of the WhatsApp statuses in relation to the impact of gender and age on the topic being used. To achieve this goal, 400 statuses were collected from Jordanian males and females who are divided into two main age groups: the first one consists of participants whose age is above 30 years old, and the second group whose participants are under 30 years old. Then, the data were analyzed quantitatively and categorized based on the main following topics; religious, social, political, economic and fixed statuses. The results show that gender and age have essential impacts on the statuses being used. For example, the religious statuses are the most frequently used topic by Jordanian females whereas the social statuses are the most frequently used topic by Jordanian males. However, the political and economic statuses are the least frequent statuses used among Jordanian. Moreover, the results show that the most frequently used topic among males who are above 30 years old is the fixed statuses suggested by the mobile itself whereas the most frequently used topic among males who are under 30 years old is the social topic. On the other hand, the impact of age among females is clearly manifested in the use of the fixed statuses suggested by the mobile itself. For instance, the females who are above 30 years old use the fixed statuses more dramatic than the females who are under 30 years old. Also, the fixed statuses are the second frequently used topic by the females who are above 30 years old whereas they are the third frequently used topic by females who are under 30 years old.


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