Phacoemulsification of cataract with low intraoperative parameters

2021 ◽  
pp. 106-108
Author(s):  
A.V. Tereshchenko ◽  
◽  
I.G. Trifanenkova ◽  
M.V. Okuneva ◽  
A.A. Oganesyan ◽  
...  
Keyword(s):  
Endothelial Cells ◽  
Intraocular Pressure ◽  
Corneal Endothelium ◽  
Functional Results ◽  
Volume Of Fluid ◽  
Main Group ◽  
Control Group ◽  
Iol Implantation ◽  
Negative Effect ◽  
Observation Period

Purpose. To evaluate the clinical and functional results after cataract phacoemulsification with implantation of an intraocular lens at reduced intraoperative intraocular pressure, adapted vacuum and aspiration. Material and methods. 12 patients (24 eyes) with immature cataracts without concomitant eye pathology were included in the study. The age of patients was from 62 to 68 years. Patients were divided into 2 groups depending on intraoperative pressure parameters. The main group included 12 eyes with immature cataracts, which underwent phacoemulsification of the cataract with a reduced intraoperative intraocular pressure. 12 paired eyes, which underwent phacoemulsification of the cataract with IOL implantation with standard settings were included in the second (retrospective) group. Postoperative examination included checking visual acuity, tonometry, endothelial microscopy. The observation period was 1 day, 1 and 6 months. Results. Phacoemulsification of the cataract in both groups was performed without complications; operations were completed with intracapsular IOL implantation. It was noted that CDE of the main group was 2.79±0.64, and it was 2.9±0.82 in the control group during analyzing intraoperative indicators. The main differences were noted in indicators of the volume of fluid aspiration: 65.4±1.21 cm3 of the main group and 74.9±2.45 cm3 of the control group. The indicator of the volume of fluid aspiration of the control group was 14% more than that of the main group. After 6 months, the number of endothelial cells of the main group ranged from 1625 to 1935 cells/mm2, in the control group the number of endothelial cells ranged from 938 to 1745 cells/mm2. Conclusions. Performing phacoemulsification of cataract at close to normotonus values of intraoperative pressure parameters, as well as adapted indicators of irrigation-aspiration and vacuum, allows to reduce the negative effect on the corneal endothelium, reducing the percentage of complications and the postoperative period of rehabilitation of patients. Key words: cataract phacoemulsification, intraoperative intraocular pressure, reduced indicators.

scholarly journals Comparative Analysis of the Clinical Efficacy of Intrastromal Keratoplasty using a Digital Marking Device in Patients with Keratoconus

2020 ◽  
Vol 17 (1) ◽  
pp. 42-48
Author(s):  
A. V. Tereshchenko ◽  
I. G. Trifanenkova ◽  
E. N. Vishnyakova ◽  
S. K. Dem’yanchenko ◽  
E. А. Nikolaev
Keyword(s):  
Visual Acuity ◽  
Comparative Analysis ◽  
Clinical Efficacy ◽  
Functional Results ◽  
Main Group ◽  
Vector Analysis ◽  
Control Group ◽  
Postoperative Astigmatism ◽  
Uncorrected Visual Acuity ◽  
Observation Period

Purpose — to perform a comparative analysis of the clinical efficacy of intrastromal keratoplasty (ISKP) in patients with keratoconus during surgery with and without Verion digital marking device.Patients and methods. 37 patients (50 eyes) with corneal astigmatism up to -5.0 diopters were included in the study. These patients were operated with the femtolaser method of ISKP with implantation of corneal segments. The average age of the patients was 27.96 ± 3.40 years. The observation period is from 3 to 12 months. All patients were divided into two groups depending on the surgical technique: Verion-assisted, using a digital marking device and taking into account the angle of cyclotorsia, or standard, without taking into account the angle of cyclotorsia. The first main group included 28 eyes (56 %), the second control group included 22 eyes (44 %) accordingly.Results. The functional results after ISKP in both groups were quite good. Stabilization of functional parameters and keratometric data was noted in the postoperative period, by 3 months. Patients of the main group showed a statistically significant (p < 0.05) increase in average uncorrected visual acuity to 0.50 ± 0.16, and visual acuity with maximum correction to 0.70 ± 0.12 (p < 0.05). The average keratometry of the weak meridian decreased to 44.3 ± 1.4 diopters, the average keratometry of the strong meridian decreased to 50.8 ± 3.2 diopters. Patients in the control group showed a statistically significant (p < 0.05) increase in average uncorrected visual acuity to 0.45 ± 0.12, and visual acuity with maximum correction to 0.60 ± 0.17. The average values of keratometry of the weak meridian decreased to 45.3 ± 1.8 diopters, the average values of keratometry of the strong meridian decreased to 51.8 ± 2.2 diopters. The results of the vector analysis reliably indicate a significantly higher accuracy of the Verion-assisted ISKP. Which is confirmed by the achieved indicators of the “success” index, the calculated astigmatism vector close to the actual postoperative astigmatism vector, the smaller the magnitude of the astigmatism axis difference vector compared to the control.Conclusion. The use of the Verion-assisted intrastromal technique for keratoconus reduces the risk of erroneous positioning of the corneal segments in the tunnel during transferring diagnostic data to the operating room. Taking into account the angle of cyclotorsia during cutting into the intrastromal tunnel increases the effective correction of the cylindrical component of refraction, which is confirmed by the main coefficients of the vector analysis by N. Alpins.

Clinical efficacy of osteopathic correction in the complex treatment of patients with unoperated open-angle glaucoma

2020 ◽  
pp. 97-105
Author(s):  
E. N. Simakova ◽  
O. V. Stenkova
Keyword(s):  
Intraocular Pressure ◽  
Drug Therapy ◽  
Primary Open Angle Glaucoma ◽  
Open Angle Glaucoma ◽  
Randomized Study ◽  
Main Group ◽  
Control Group ◽  
Open Angle ◽  
Complex Treatment ◽  
Hypotensive Drug

Introduction. Glaucoma is one of the most significant eye diseases. It is often diagnosed, not always amenable to therapy, and can lead to a complete loss of visual functions. In recent years, the method of osteopathic correction has become widespread as one of the effective methods of treatment and rehabilitation of patients with pathologies of various body systems. In the pathogenesis of glaucoma, it is customary to distinguish a dystrophic concept, which considers primary open-angle glaucoma as a result of dystrophic changes in the connective tissue, as well as in the endothelial lining of the trabeculae and Schlemm′s canal, especially destructive changes in mitochondria and the alteration of their functional activity. A vascular concept is also distinguished. According to this concept, the central link in the pathogenesis of glaucoma is circulatory disorder in the ciliary vessels, ocular artery, and major vessels of the head and neck, it can be assumed that osteopathic correction in the treatment of patients with open-angle glaucoma will be pathogenetically substantiated and will have a positive effect on intraocular pressure and trophicity of the optic nerve. The goal of research — to study the influence of in osteopathic correction on the nature of unoperated glaucoma (stage IIA) and to substantiate the possibility of using osteopathic correction in the complex treatment of patients with this pathology.Materials and methods. A prospective controlled randomized study was conducted at 52 city polyclinics, branch 3, Moscow, from January 2018 to January 2019. 40 patients (70 eyes) aged 50 to 75 years with primary open-angle glaucoma IIA stage were examined. At this stage of the disease, patients most often seek medical care and the issue of conservative management is primarily considered. All patients were divided into two groups of 20 people: the main group and the control group. The treatment in the main group included hypotensive drug therapy and osteopathic correction. Patients of the control group received only drug therapy. All patients underwent ophthalmic (visometry, tonometry, perimetry) and osteopathic examination twice: before the treatment and after 3 months.Results. For patients with primary open-angle IIA non-operated glaucoma, regional (most often regions of the head, neck, dura mater) and local (abdominal diaphragm, iliac bones, hip and knee joints) somatic dysfunctions were the most typical. In the main group a statistically significant decrease in the frequency and severity of dysfunctions at all levels was stated. Also, in patients receiving osteopathic correction, a significant decrease in the level of intraocular pressure and perimetric indices was noted. In patients of the control group, no reliable changes in these indicators were obtained.Conclusion. The results obtained indicate that osteopathic correction is clinically effective in the complex treatment of patients with primary open-angle II A glaucoma.

Experimental rationale for using a viscoprotection of the corneal endothelium on the graft formed with a femtosecond laser for the descemet stripping endothelial keratoplasty

2021 ◽  
pp. 94-96
Author(s):  
I.S. Tkachenko ◽  
◽  
B.E. Malyugin ◽  
S.A. Borzenok ◽  
D.S. Ostrovskiy ◽  
...  
Keyword(s):  
Endothelial Cells ◽  
Femtosecond Laser ◽  
Corneal Endothelium ◽  
Hydroxypropyl Methylcellulose ◽  
Lamellar Keratoplasty ◽  
Confocal Laser ◽  
Control Group ◽  
Endothelial Keratoplasty ◽  
Descemet Stripping Endothelial Keratoplasty ◽  
Experimental Group

Purpose. To rationale experimentally the use of a viscoprotection of the corneal endothelium on the graft formed with a femtosecond laser for the descemet stripping endothelial keratoplasty. Material and methods. In our study, we used 12 pig's corneoscleral discs. The preservation time before the experiment averaged 12±4 hours. The corneas were divided into 2 groups. In the operating room, the graft was formed using an LDV Z8 femtosecond laser (Ziemer, Switzerland) from the endothelial side. Before applanation of the donor cornea and femtolaser head, a 1% solution of hydroxypropyl methylcellulose (HPMC) was applied to the endothelium - experimental group. The control group was appraised according to the standard technique, with the application of a few drops of a solution for storing the corneas. Then the applanation was monitored and evaluated by laser optical coherence tomography. Then the graft was separated from the bed and transferred to a conservation medium. Under laboratory conditions, to determine the viability of endothelial cells, the graft was stained with a «vital» dye with the commercial name Life and Dead (Abcam, UK) and placed in a confocal laser scanning microscope. Endothelial cells were counted using the ImageJ software. Results. In the experimental and control groups, the number of living endothelial cells (EC) was 91.06±1.49% and 83.86±2.14%, respectively (p<0.001). The number of dead ECs in the control group was 7.2±0.65% more than in the experimental group and amounted to 16.14±2.14% and 8.94±1.49%, respectively (p<0.001). Conclusion. The study demonstrated that the use of viscoprotection of the corneal graft endothelium for posterior lamellar keratoplasty is quite effective, and significantly reduces the loss of EC at the stage of cutting out the graft with a femtosecond laser. Key words: descemet stripping endothelial keratoplasty, femtosecond laser, vital dyes.

Effects of 0.5% and 0.25% Apraclonidine on Postoperative Intraocular Hypertension after Cataract Extraction

1998 ◽  
Vol 8 (2) ◽  
pp. 67-70 ◽  
Author(s):  
S. Simsek ◽  
A. Demirok ◽  
T. Yasar ◽  
A. Çinal ◽  
A. Bayram ◽  
...  
Keyword(s):  
Intraocular Pressure ◽  
Side Effects ◽  
Prospective Study ◽  
Cataract Extraction ◽  
Control Group ◽  
Extracapsular Cataract Extraction ◽  
Artificial Tears ◽  
Iol Implantation ◽  
The Third ◽  
Applanation Tonometer

Purpose We conducted a double-masked, prospective study to evaluate the effect of 0.5% and 0.25% apraclonidine on postoperative intraocular pressure (IOP) in patients undergoing extracapsular cataract extraction (ECCE) with intraocular lens (IOL) implantation. Methods Fifty-four patients scheduled for ECCE were randomly divided into three groups of 18. The first group received one drop of 0.50% apraclonidine topically one hour before surgery and immediately after the end of the procedure. The second group received the same regimen but with 0.25% apraclonidine. The third group received artificial tears as the control group. IOP was measured 12 h preoperatively and 6 and 24 h postoperatively. All the measurements were made using the same Goldmann applanation tonometer by the same surgeon who did not know to which group the patient belonged. Results Preoperative mean IOP was 13.66 ± 2.76 mmHg in the first group, 14.27 ± 2.24 mmHg in the second and 14.5 ± 1.34 mmHg in the control group. The differences were not significant (p=0.398). Mean IOP at the early postoperative visit (6 h) was significantly lower in the first group (17.44 ± 4.95 mmHg) than the second (21.78 ± 7.19 mmHg) and the control group (24.55 ± 5.65 mmHg) (p<0.001). Mean postoperative IOP at 24 h was again significantly lower in the first group (14.33 ± 3.75 mmHg) than the second (17.11 ± 4.16 mmHg) and the control group (19.61 ± 3.20 mmHg) (p<0.001). Conclusions Our findings indicate that topical 0.5% apraclonidine controlled early postoperative intraocular hypertension after cataract extraction without any side effects, while the 0.25% drops were not effective.

scholarly journals Comparison of Cornea Endothelial Cells Density the After Aspiration of Dense Cataracts using Two Variants of Phacoemulsification Parameters

2018 ◽  
Vol 15 (2S) ◽  
pp. 145-152
Author(s):  
S. V. Shukhaev ◽  
E. V. Boiko
Keyword(s):  
Endothelial Cells ◽  
Postoperative Complications ◽  
Cell Loss ◽  
Main Group ◽  
Cell Counting ◽  
Control Group ◽  
Corneal Endothelial Cells ◽  
Significant Difference ◽  
Ultrasound Energy ◽  
And Control

Purpose: to compare two types of phacoemulsification parameters (combination ultrasound and torsional US with IP) with estimating the number of postoperative complications caused by intraoperative trauma of corneal endothelial cells.Patients and methods. 72 patients underwent phacoemulsification with IOL implantation. Patients were randomly divided into two groups (main n = 33 and control n = 39). During the aspiration of lens fragments in the main group the combination ultrasound was used, while torsional US with IP was used in the control group. Endothelial cell counting and other examinations were performed 1 day, 1 week and 6 months after the surgery.Results. CDVA in the explored groups 1 week after the surgery was similar: the main group — 0.813 ± 0.228, the control group — 0.765 ± 0.250, There was also no statistically significant difference in the thickness of the cornea between the groups: the main group — 533.48 ± 12.41, the control group — 536.44 ± 10.92. At the same time, a statistically significant difference was found in the density of endothelial cells: the main group: 1871.30 ± 187.41 (after 1 week), 1865 ± 178.9 (after 6 months); control group: 1809.63 ± 225.43 (after 1 week), 1791 ± 230.82 (after 6 months). The percentage of cell loss was, respectively, lower in the main group at all times of observation: 3.90% (after 1 day), 4.54% (after 1 week), 4.9% (after 6 months). In the control group: 7.71% (after 1 day), 9.25% (after 1 week), 10.4% (after 6 months).Conclusions. Data obtained in this study has showed the advantages of combination ultrasound in comparison with torsional US with IP, when performing aspiration of dense lenses. Due to lower consumption of ultrasound energy and higher aspiration rate of the fragments, combination ultrasound can reduce the loss of corneal endothelial cells and decrease the number and severity of postoperative complications associated with it. 

scholarly journals Progressive spectacle correction in patients with ametropia and primary open-angle glaucoma

The Eye ◽  
2019 ◽  
Vol 125 (2019-1) ◽  
pp. 6-12
Author(s):  
Irina Gndoyan ◽  
Natalya Kuznetsova ◽  
Alexander Derevyanchenko
Keyword(s):  
Intraocular Pressure ◽  
Aqueous Humor ◽  
Primary Open Angle Glaucoma ◽  
Open Angle Glaucoma ◽  
Main Group ◽  
Control Group ◽  
Open Angle ◽  
Aqueous Humor Outflow ◽  
Vision Correction ◽  
Spectacle Correction

Purpose: To determine the role that progressive spectacle lenses play in intraocular pressure compensation and stabilization of the glaucomatous process in patients with primary open-angle glaucoma (POAG) combined with presbyopia and refractive errors. Material and methods. 29 patients (53 eyes) aged 43 to 67 years with I-II stage POAG and a certain type of refractive error were enrolled into study. All patients had intraocular pressure (IOP) compensated to the target level on medication. Patients of the main group (17 people, 32 eyes) used universal progressive spectacle lenses with optimized surface. The patients of the control group (12 people, 21 eyes) used separate monofocal glasses for near and distance vision as a method of ametropia correction. Visual acuity test, refractometry, pneumotonometry, tonography, automated static perimetry were applied for monitoring the patients. The measurements were taken before spectacle correction and a year after its prescription. Results. A decrease of IOP (p=0.01) and an increase of the aqueous humor outflow coefficient (p<0.01) were determined after one year use of the recommended type of vision correction in the main group, whereas in the control group there was an increased level of IOP (p<0.05) and a reduced aqueous humor outflow coefficient (p<0.2). Conclusion. The use of progressive spectacle lenses as a method of permanent vision correction reliably reduces IOP and improves the aqueous humor outflow in patients with early-stage POAG. The absence of negative visual field dynamics indicates the stabilization of the glaucomatous process.

Evaluation of the effect on the biological status of young sheep when using a symbiotic feed additive

2021 ◽  
Vol 1 (5) ◽  
pp. 57-62
Author(s):  
R. F. Ivannikova ◽  
◽  
N. V. Pimenov ◽  
Keyword(s):  
Animal Species ◽  
Live Weight ◽  
Feed Additives ◽  
Feed Additive ◽  
Control Group ◽  
Genus Bacillus ◽  
Negative Effect ◽  
Positive Effect ◽  
Spore Forming Bacteria ◽  
Observation Period

The article presents the results of studies on the use of synbiotic feed additives based on live spore-forming bacteria of the genus Bacillus, lysates of lactic acid bacteria and yeast to lambs of 10-day-old Volgograd breed in various doses. The use of the feed additive did not have a negative effect on the morphological parameters of the lambs ' blood. Physiological parameters for the entire observation period were within the reference values characteristic of this animal species. The positive effect of synbiotic feed additive was manifested by higher growth rates – an increase in the live weight of the lambs of the experimental groups compared to the control group.

The results of surgical treatment of the patients with a cochlear form of otosclerosis

2019 ◽  
Vol 18 (5) ◽  
pp. 46-53
Keyword(s):  
Surgical Treatment ◽  
Bone Conduction ◽  
Functional Results ◽  
Main Group ◽  
Differential Diagnostics ◽  
Control Group ◽  
Efficient Treatment ◽  
And Control

Despite the progress in otosurgery, the efficient treatment of patients with the cochlear form of otosclerosis (according to the classification of N.A. Preobrazhensky, 1962) remains an important task. The authors have developed and implemented an advanced stapedoplasty method, providing the improvement of hearing in this category of patients. and described the methods of differential diagnostics for selection of patients according to the developed method. The article describes in details the early and long-term functional results of surgical treatment of 60 patients with cochlear and mixed II forms of otosclerosis, divided into the main and control groups. The main group is represented by 30 patients who underwent a cartilage-on-vein stapedoplasty according to the improved method. The control group included 30 patients, in which 18 people underwent a cartilage-on-vein stapedoplasty according to the method developed by Lenin Prize winner V. F. Nikitina, and 12 people who underwent V. T. Palchun’s piston stapedoplasty. The results demonstrate a statistically significant improvement of bone conduction in the main group in average by 15–20 dB throughout the entire tone scale (except for high frequencies in some patients) and the complete closure of the bone-air interval with subsequent preservation of the results. Based on the obtained data, the authors present the expediency and perspectivity of implementation of the advanced stapedoplasty method.

scholarly journals EVALUATION OF EFFECTIVENESS OF TREATMENT-AND-PROPHYLACTIC COMPLEX IN TOBACCO-ADDICTED PATIENTS WITH CHRONIC GENERALIZED PERIODONTITIS ON THE BACKGROUND OF CHRONIC HYPERACID GASTRITIS

2020 ◽  
Vol 73 (12) ◽  
pp. 2607-2611
Author(s):  
Olena L. Zolotukhina ◽  
Iuliia G. Romanova ◽  
Tetyana O. Pyndus ◽  
Georgy O. Romanov ◽  
Iryna M. Tkachenko
Keyword(s):  
Helicobacter Pylori ◽  
Tobacco Smoking ◽  
Main Group ◽  
Control Group ◽  
Healthy Individuals ◽  
Men And Women ◽  
Basic Therapy ◽  
Periodontal Indices ◽  
Efficacy Of Treatment ◽  
Observation Period

The aim: To evaluate the clinical efficacy of treatment-and-prophylactic complex in patients addicted to tobacco with chronic generalized periodontitis with chronic hyperacid gastritis. Materials and methods: 68 patients (men and women) aged 25–44 years were examined. They were distributed into two groups: the main group — 48 patients addicted to tobacco with chronic generalized 1 degree periodontitis and chronic hyperacid gastritis, associated with Helicobacter pylori, the control group — 20 healthy individuals without bad habits. Patients of the main group were distributed at random into 2 subgroups (1.1, 1.2) depending on the chosen therapy. The patients of the subgroup 1.1 received the basic therapy and the developed treatment and prophylactic complex, the subgroup 1.2 received the basic therapy and the ultraphonophoresis procedures with placebo. Assessment of the effectiveness of therapy was carried out by determining hygienic index OHI-S and periodontal indices (PI, PMA index and Muhlemann bleeding index (MBI)). Results: The usage of the treatment-and-prophylactic complex resulted in improvement of the hygienic index OHI-S and periodontal indices (PI, PMA index and MBI) at the immediate and late observation period. Conclusions: Results of the study confirmed the effectiveness of the proposed treatment-and-prophylactic complex in therapy of chronic generalized 1 degree periodontitis in patients addicted to tobacco smoking with chronic hyperacid gastritis.

scholarly journals THE STUDY OF RESULTS OF SURGICAL TREATMENT OF PATIENTS WITH VERTEBRAL-SPINAL TRAUMA

2010 ◽  
Vol 16 (2) ◽  
pp. 64-67
Author(s):  
B. Sh. Minasov ◽  
A. R. Sahabutdinova ◽  
M. Yu. Khanin
Keyword(s):  
Spinal Cord ◽  
Spinal Cord Injury ◽  
Surgical Treatment ◽  
Functional Results ◽  
Main Group ◽  
Medical Rehabilitation ◽  
Control Group ◽  
Late Period ◽  
Therapeutic Exercises ◽  
Cord Injury

A study of the efficacy of medical rehabilitation of 170 patients with spinal-cord injury through the application of modern rehabilitation and surgical technologies was conducted. Patients of I (control) group received standard set of conservative treatment and rehabilitation. Patients of II (main) group the rehabilitation was supplemented with therapeutic exercises with the use of loop complex «Hope» and the rate of adaptation to the stress of hypoxia in the late period of injury. Patient of III (control) group surgical treatment and the conventional range of rehabilitation were performed. Patients of IV (main) group the rehabilitation was completed with early activation using espandernogo complex «Hope» and the rate of adaptation to the stress of hypoxia in the late period of injury. It is proved that the developed complex rehabilitation of patients with spinal-cord injury using an early stable functional osteosynthesis with the minimum extent necessary, the use of complex «Hope» can improve the functional results at the expense of early motor activation, preventing the formation of contractures and muscle atrophy. The use of adaptation to the stress of hypoxia in the late period of vertebro-spinal cord injury improves overall health, reduces the severity of autonomic reactions, emotional stress, can cut pain syndromes.

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