scholarly journals Comparative Analysis of the Clinical Efficacy of Intrastromal Keratoplasty using a Digital Marking Device in Patients with Keratoconus

2020 ◽  
Vol 17 (1) ◽  
pp. 42-48
Author(s):  
A. V. Tereshchenko ◽  
I. G. Trifanenkova ◽  
E. N. Vishnyakova ◽  
S. K. Dem’yanchenko ◽  
E. А. Nikolaev
Keyword(s):  
Visual Acuity ◽  
Comparative Analysis ◽  
Clinical Efficacy ◽  
Functional Results ◽  
Main Group ◽  
Vector Analysis ◽  
Control Group ◽  
Postoperative Astigmatism ◽  
Uncorrected Visual Acuity ◽  
Observation Period

Purpose — to perform a comparative analysis of the clinical efficacy of intrastromal keratoplasty (ISKP) in patients with keratoconus during surgery with and without Verion digital marking device.Patients and methods. 37 patients (50 eyes) with corneal astigmatism up to -5.0 diopters were included in the study. These patients were operated with the femtolaser method of ISKP with implantation of corneal segments. The average age of the patients was 27.96 ± 3.40 years. The observation period is from 3 to 12 months. All patients were divided into two groups depending on the surgical technique: Verion-assisted, using a digital marking device and taking into account the angle of cyclotorsia, or standard, without taking into account the angle of cyclotorsia. The first main group included 28 eyes (56 %), the second control group included 22 eyes (44 %) accordingly.Results. The functional results after ISKP in both groups were quite good. Stabilization of functional parameters and keratometric data was noted in the postoperative period, by 3 months. Patients of the main group showed a statistically significant (p < 0.05) increase in average uncorrected visual acuity to 0.50 ± 0.16, and visual acuity with maximum correction to 0.70 ± 0.12 (p < 0.05). The average keratometry of the weak meridian decreased to 44.3 ± 1.4 diopters, the average keratometry of the strong meridian decreased to 50.8 ± 3.2 diopters. Patients in the control group showed a statistically significant (p < 0.05) increase in average uncorrected visual acuity to 0.45 ± 0.12, and visual acuity with maximum correction to 0.60 ± 0.17. The average values of keratometry of the weak meridian decreased to 45.3 ± 1.8 diopters, the average values of keratometry of the strong meridian decreased to 51.8 ± 2.2 diopters. The results of the vector analysis reliably indicate a significantly higher accuracy of the Verion-assisted ISKP. Which is confirmed by the achieved indicators of the “success” index, the calculated astigmatism vector close to the actual postoperative astigmatism vector, the smaller the magnitude of the astigmatism axis difference vector compared to the control.Conclusion. The use of the Verion-assisted intrastromal technique for keratoconus reduces the risk of erroneous positioning of the corneal segments in the tunnel during transferring diagnostic data to the operating room. Taking into account the angle of cyclotorsia during cutting into the intrastromal tunnel increases the effective correction of the cylindrical component of refraction, which is confirmed by the main coefficients of the vector analysis by N. Alpins.

scholarly journals Comparative Analysis of Clinical and Functional Results and Position of Intraocular Lens after Femtolaser-Assisted and Standard Cataract Phacoemulsification

2019 ◽  
Vol 4 (4) ◽  
pp. 139-144
Author(s):  
I. L. Kulikova ◽  
N. S. Timofeyeva
Keyword(s):  
Visual Acuity ◽  
Comparative Analysis ◽  
Intraocular Lens ◽  
Functional Results ◽  
Higher Order ◽  
Significant Difference ◽  
Corrected Distance Visual Acuity ◽  
Capsular Bag ◽  
Observation Period

Modern surgical treatment of cataracts provides effective results. The study of the position of the intraocular lens (IOL) in the capsule bag can be considered as one of the most important factors influencing the final visual and refractive result of the operation.Aim: comparative analysis of clinical and functional results and position of the IOL in the capsular bag, namely decentration and tilt, when performing femtolazer-assisted phacoemulsification (FLACS) and standard phacoemulsification (CPCS). Materials and methods. We surveyed 57 patients (57 eyes). FLACS was performed in 27 patients, CPCS – in 30 patients. Standard methods of research were used, determination of the position of the IOL (decentration and tilt) in the capsular bag on the device OCT-Casia2 (TOMEY, Germany) and study of wave front were conducted.Results. Comparative analysis of the obtained results showed no significant difference between groups in postoperative visual acuity, however, there was the trend towards higher performance corrected distance visual acuity and uncorrected distance in the group FLACS (0.68 ± 0.18 and 0.74 ± 0.2) compared to the group CPCS (0.58 ± 0.28 and 0.65 ± 0.24). Internal higher order aberrations were significantly low in the group with femtolazer accompaniment: in 3 mm zone almost 2 times (p = 0.041), in 5 mm zone 1.3 times (p = 0.047). Vertical decentration in a CPCS group made 0.217 ± 0.26 mm, in FLACS group – 0.118 ± 0.05 mm, the vertical tilt – 0.75 ± 0.37° and 0.54 ± 0.36 respectively. Conclusion. Decentralizations and IOL tilt tended to lower indices in the FLACS during the observation period up to 2 months after the operation, which was accompanied by lower values of higher order internal aberrations.

scholarly journals Prompt neutralization of traumatic hyperthermic factors of burn injuries in children at the stages of selfhelp, mutual assistance and first aid

2021 ◽  
pp. 38-44
Author(s):  
V.I. Nagaychuk ◽  
◽  
R.M. Chornopischuk ◽  
O.A. Nazarchuk ◽  
◽  
...  
Keyword(s):  
Comparative Analysis ◽  
Clinical Effectiveness ◽  
Functional Results ◽  
First Aid ◽  
Main Group ◽  
The Body ◽  
Burn Injuries ◽  
Control Group ◽  
Surgical Interventions ◽  
Mutual Assistance

Occupying a leading position in the structure of general injuries, burn injuries in children remain an urgent issue of combustiology in particular and medicine in general. At the same time, many issues related to the organization of first aid to such patients still remain unregulated. To this end, a study aimed at conducting a comparative analysis of the clinical effectiveness of emergency care for children with burn injuries, including the use of the suggested algorithm, was conducted. Materials and methods. 153 cases of burn injuries with boiling water of IIab–III degree on the area of 10–40% of the body surface in children aged from 8 months to 16 years, who were treated at the Clinical Center for Thermal Injury and Plastic Surgery of the Municipal Non-profit Enterprise «Vinnytsia Regional Pirogov Clinical Hospital Vinnytsya Regional Council» in the period of 2015–2020 were analyzed. All patients underwent comprehensive diagnosis and treatment including surgery. Depending on the nature of first aid, children were divided into two groups: patients of the main group (n=97) underwent prompt neutralization of the traumatic effects of exogenous hyperthermic factors on the injured areas from the moment the injury was sustained. Childrenin the control group (n=56) sought help on the 5th–14th day after the injury. The duration of prompt neutralization did not exceed 15 minutes or was not performed at all. It was often combined with the irrational use of pharmacological agents and folk remedies. Results. Comparative analysis of the course of the disease in children of the main group and the comparison group reliably confirmed the benefits of prompt neutralization of traumatic effects of hyperthermic exogenous and endogenous damage factors in burn injuries manifested by a more favorable course of the disease, faster improvement, lower local and systemic inflammatory response, shorter hospital stay with less occurrence of various complications, repeated surgical interventions, better aesthetic and functional results. Conclusions. The obtained results objectively confirmed the importance and effectiveness of the suggested system of organization of care for children with burn injuries, especially at the stages of self-help, mutual assistance and first aid. The research was carried out in accordance with the principles of the Helsinki Declaration. The study protocol was approved by the Local Ethics Committee of these Institutes. The informed consent of the patient was obtained for conducting the studies. The authors declare no conflicts of interests. Key words: burn injuries, children, first aid, traumatic hyperthermic agents, neutralization.

Phacoemulsification of cataract with low intraoperative parameters

2021 ◽  
pp. 106-108
Author(s):  
A.V. Tereshchenko ◽  
◽  
I.G. Trifanenkova ◽  
M.V. Okuneva ◽  
A.A. Oganesyan ◽  
...  
Keyword(s):  
Endothelial Cells ◽  
Intraocular Pressure ◽  
Corneal Endothelium ◽  
Functional Results ◽  
Volume Of Fluid ◽  
Main Group ◽  
Control Group ◽  
Iol Implantation ◽  
Negative Effect ◽  
Observation Period

Purpose. To evaluate the clinical and functional results after cataract phacoemulsification with implantation of an intraocular lens at reduced intraoperative intraocular pressure, adapted vacuum and aspiration. Material and methods. 12 patients (24 eyes) with immature cataracts without concomitant eye pathology were included in the study. The age of patients was from 62 to 68 years. Patients were divided into 2 groups depending on intraoperative pressure parameters. The main group included 12 eyes with immature cataracts, which underwent phacoemulsification of the cataract with a reduced intraoperative intraocular pressure. 12 paired eyes, which underwent phacoemulsification of the cataract with IOL implantation with standard settings were included in the second (retrospective) group. Postoperative examination included checking visual acuity, tonometry, endothelial microscopy. The observation period was 1 day, 1 and 6 months. Results. Phacoemulsification of the cataract in both groups was performed without complications; operations were completed with intracapsular IOL implantation. It was noted that CDE of the main group was 2.79±0.64, and it was 2.9±0.82 in the control group during analyzing intraoperative indicators. The main differences were noted in indicators of the volume of fluid aspiration: 65.4±1.21 cm3 of the main group and 74.9±2.45 cm3 of the control group. The indicator of the volume of fluid aspiration of the control group was 14% more than that of the main group. After 6 months, the number of endothelial cells of the main group ranged from 1625 to 1935 cells/mm2, in the control group the number of endothelial cells ranged from 938 to 1745 cells/mm2. Conclusions. Performing phacoemulsification of cataract at close to normotonus values of intraoperative pressure parameters, as well as adapted indicators of irrigation-aspiration and vacuum, allows to reduce the negative effect on the corneal endothelium, reducing the percentage of complications and the postoperative period of rehabilitation of patients. Key words: cataract phacoemulsification, intraoperative intraocular pressure, reduced indicators.

scholarly journals Analysis of Clinical and Functional Results of the Developed Technology of Combined Laser Treatment of Initial Stages of Idiopathic Epiretinal Membrane

2019 ◽  
Vol 4 (4) ◽  
pp. 20-23
Author(s):  
K. P. Takhchidi ◽  
G. F. Kachalina ◽  
T. A. Kasminina ◽  
E. P. Tebina
Keyword(s):  
Visual Acuity ◽  
Laser Treatment ◽  
Epiretinal Membrane ◽  
Comparison Group ◽  
Functional Results ◽  
Main Group ◽  
Control Group ◽  
Idiopathic Epiretinal Membrane ◽  
Treatment Comparison ◽  
Group A

Aim. To analyze the clinical and functional results of the combined technology for laser treatment of patients with the initial stages of idiopathic epiretinal membrane.Methods. This study included 3 groups of patients: the main group (32 patients) after the combined laser technology (subthreshold “grid” laser photocoagulation (LP) and subthreshold micropulse LP); control group (30 patients) which did not receive any treatment; comparison group (30 patients) after subthreshold “grid” LP. The assessment uncorrected visual acuity (UCVA), best corrected visual acuity (BCVA), central retinal thickness (CRT) and central retinal sensitivity (CRS) was performed. The follow-up period was 5 years.Results. In the control group a slow decrease of UCVA, BCVA, CRS (p < 0.05) and an increasing CRT (p < 0.05) were observed. In the main group maximal UCVA, BCVA, CRS (p < 0.05) were marked from 3 to 6 months after laser treatment and there was a gradual decrease in the CRT indices. In the comparison group, a short-term positive effect was achieved up to 3 months with an increase of UCVA, BCVA, CRS (p < 0.05). 12 months post op there was an increase in CRT with a decrease of UCVA, BCVA, and CRS until the end of study.Conclusion. The technology of combined laser treatment showed high efficiency in control and comparison groups, with stabilization/increase of UCVA, BCVA, CRS and stabilization/improvement of the morphological parameters of the retina – the decrease of CRT with ERM involution.

scholarly journals Efficiency of minimally invasive surgery for liver echinococcosis and its complications

2021 ◽  
Vol 26 (1) ◽  
pp. 84-91
Author(s):  
Z. A. Azizzoda ◽  
K. M. Kurbonov ◽  
K. R. Ruziboyzoda ◽  
S. G. Ali-Zade
Keyword(s):  
Minimally Invasive Surgery ◽  
Comparative Analysis ◽  
Surgical Treatment ◽  
Liver Resection ◽  
Minimally Invasive ◽  
Postoperative Mortality ◽  
Main Group ◽  
Control Group ◽  
Surgical Methods ◽  
Access Surgery

Aim. Improving outcomes of diagnosis and treatment of patients with liver echinococcosis and its complications. Materials and methods. A comparative analysis of the results of surgical treatment of liver echinococcosis and its complications with traditional laparotomy access surgery (control group) and minimally invasive interventions (main group) was performed.Results. The study included 300 patients (170 in the control and 130 in the main group). In the main group, 37 (28.4%) cases performed open echinococcectomy from various mini-accesses, and 27 (20.7%) performed twostage operations using minimally invasive technology. Laparoscopic echinococcectomy was performed in 23 (17.7%) patients, laparoscopic pericystectomy 12 (9.2%) and laparoscopic liver resection in 10 (7.7%) patients. The frequency of postoperative complications in the main group was 17.7%, in the control 51.8%, postoperative mortality decreased from 2.3% to 0.8%.Conclusion. Minimally invasive technologies in the surgical treatment of liver echinococcosis show the better immediate results compared to traditional open surgical methods.

Impact of spectacles wear on uncorrected visual acuity among urban migrant primary school children in China: a cluster-randomised clinical trial

2020 ◽  
pp. bjophthalmol-2020-316213
Author(s):  
Xinwu Zhang ◽  
Ming Zhou ◽  
Xiaochen Ma ◽  
Hongmei Yi ◽  
Haiqing Zhang ◽  
...  
Keyword(s):  
Clinical Trial ◽  
Visual Acuity ◽  
School Children ◽  
Randomised Clinical Trial ◽  
Primary School Children ◽  
Control Group ◽  
Cluster Randomised ◽  
Uncorrected Visual Acuity ◽  
Chinese School ◽  
Urban Migrant

ObjectiveTo estimate the effect of providing free spectacles on uncorrected visual acuity (VA) among urban migrant Chinese school children.DesignExploratory analysis from a parallel cluster-randomised clinical trial.MethodsAfter baseline survey and VA screening, eligible children were randomised by school to receive one of the two interventions: free glasses and a teacher incentive (tablet computer if ≥80% of children given glasses were wearing them on un-announced examination) (treatment group) or glasses prescription and letter to parents (control group). The primary outcome was uncorrected logarithm of the minimal angle of resolution (LogMAR) VA at study closeout, adjusted for baseline uncorrected VA.ResultsAmong 4376 randomly selected children, 728 (16.6%, mean age 10.9 years, 51.0% boys) at 94 schools failed VA screening and met eligibility criteria. Of these, 358 children (49.2%) at 47 schools were randomised to treatment and 370 children (50.8%) at 47 schools to control. Among these, 679 children (93.3%) completed follow-up and underwent analysis. Spectacle wear in the treatment and control groups was 68.3% and 29.3% (p<0.001), respectively. Uncorrected final VA for eyes of treatment children was significantly better than control children, adjusting only for baseline VA (difference of 0.039 LogMAR units, 95% CI: 0.008, 0.070, equivalent to 0.39 lines, p=0.014) or baseline VA and other baseline factors (0.040 LogMAR units, 95% CI 0.007 to 0.074, equivalent to 0.40 lines, p=0.020).ConclusionWe found no evidence that spectacles wear worsens children’s uncorrected VA among urban migrant Chinese school children.

scholarly journals Preliminary experiences with limbal relaxing incision for treatment of astigmatism during phacoemulsification

1970 ◽  
Vol 1 (2) ◽  
pp. 90-94 ◽  
Author(s):  
BR Sharma ◽  
A Kumar
Keyword(s):  
Visual Acuity ◽  
Analysis Method ◽  
Surgically Induced Astigmatism ◽  
Early Experiences ◽  
Postoperative Astigmatism ◽  
Uncorrected Visual Acuity ◽  
Induced Astigmatism ◽  
The Mean ◽  
Surgically Induced ◽  
Relaxing Incisions

Introduction: This small study relates our early experiences with the Limbal Relaxing Incision (LRI) for management of astigmatism in patients undergoing cataract surgery. Aims: To evaluate the efficacy of LRI in the management of primary astigmatism when combined with phacoemulsification. Subjects and methods: Limbal relaxing incisions were performed to correct primary astigmatism in 12 eyes of 12 cataract patients who underwent phacoemulsification as the primary procedure. The length and number of incisions were determined using the AMO LRI calculator software programme using Donnenfield and NAPA nomograms. Keratometric astigmatism was measured preoperatively and postoperatively on day 1 and after 3 weeks or more. Surgically-induced astigmatism (SIA) and the intended angle of error were evaluated by the vector analysis method. Preoperative and postoperative uncorrected visual acuity (UCVA) and best spectacle corrected visual acuity (BSCVA) were evaluated in each visit. Results: The mean age of patients was 52.92 ±10.91 years. There were 75 % male and 25 % female patients. The mean keratometric preoperative astigmatism was 2.08 ±1.05 diopter. The mean 1st postoperative day keratometric astigmatism was 1.74 ±1.32 diopter and the mean final keratometric astigmatism at 3 weeks postoperatively was 1.05± 0.68 diopter. The mean SIA on the 1st postoperative day was 2.97 ±1.72 diopter at 103.25±56.57 degree with intended angle of error 6.53±9.61 degree. The mean SIA on the 3rd postoperative week was 2.26±0.87 Diopter at 107.08±49.96 degrees with intended angle of error 2.90±7.87 degrees. Conclusion: Limbal relaxing incisions are effective method to reduce postoperative astigmatism with good predictability of intended angle. Keywords: limbal relaxing incision (LRI); uncorrected visual acuity (UCVA); surgically induced astigmatism (SIA); angle of error; target astigmatic treatment (TAT) DOI: 10.3126/nepjoph.v1i2.3681 Nep J Oph 2009;1(2):90-94

EVALUATING THE EFFECTIVENESS OF FRUCTOSE-1,6-DIPHOSPHATE IN TREATING OF OCULAR ISCHEMIC SYNDROME

2015 ◽  
Vol 8 (2) ◽  
Author(s):  
Dilbar Makhkamova
Keyword(s):  
Visual Acuity ◽  
Standard Therapy ◽  
Main Group ◽  
Doppler Imaging ◽  
Nerve Tissue ◽  
Neuroprotective Activity ◽  
Control Group ◽  
Ocular Ischemic Syndrome ◽  
Comprehensive Therapy ◽  
Ischemic Syndrome

The purpose of this study was to evaluate the efficacy and safety of FDP in patients with ocular ischemic syndrome.Material and methods. The material for this study is based on results of a comprehensive examination and treatment of 53 patients with a diagnosis OIS. The average age of the patients was 57,8 ± 6,82 year. 19 of them women, 34 men.  27 patients entered to the main group (1) which received standard therapy in combination with intravenous FDP (fructose 1,6-bisphosphate). 26 patients in the control group (2) received standard treatment.Results.  In applying the FDP combined with comprehensive therapy in the main group resulted in increased of visual acuity by 32.8%, parameters of retinal sensitivity by 17.8%, reducing the area of scotomas compared with patients of the control group. Optical coherence tomography registered significant changes in the dynamics in patients of the main group - reducing the edema and restoration of  RNFL and ONH. Recovery of visual function may have contributed neuroprotective activity of the drug FDP by a protective effect on nerve tissue, reducing the effects of hypoxic stress.Conclusions. The use of standard therapy in combination with FDP in the treatment of ocular ischemic syndrome has a positive effect on the course of the disease, thereby, increase of visual acuity, a decrease in sectoral loss in vision fields, the positive dynamics OCT parameters, improving hemodynamic parameters at Doppler imaging in dynamics.

scholarly journals The tolerability and clinical efficacy of “OKOMISTIN” in combination with “Oftalmoferon” in comparison to “Oftalmoferon” as monotherapy in the treatment of adenoviral eye diseases

2013 ◽  
Vol 6 (4) ◽  
pp. 51-54 ◽  
Author(s):  
Yury Sergeevich Astakhov ◽  
Vitaly Olegovich Sokolov ◽  
Natalia Vladimirovna Morozova ◽  
Dmitrii Alexandrovich Borisov ◽  
Galina Viktorovna Polovinkina ◽  
...  
Keyword(s):  
Clinical Efficacy ◽  
Main Group ◽  
Eye Diseases ◽  
Control Group ◽  
Allergic Reactions ◽  
Significant Morbidity ◽  
Important Goal ◽  
Clinical Recovery ◽  
Combined Use ◽  
Acute Conjunctivitis

Rationale. Adenovirus accounts for 48% to 62% of the cases of acute conjunctivitis [3, 4], and causes significant morbidity. Because of this, an important goal of clinical research is to find new medications which are effective in reducing the symptoms and which are easily tolerated. Objective. To estimate the tolerability and clinical efficacy of “Okomistin” in combination with “Oftalmoferon” in comparison to “Oftalmoferon” as monotherapy in the treatment of adenoviral eye diseases. Material and methods. 42 patients with adenoviral conjunctivitis were monitored. Their age ranged from19 to 59 years. Patients were divided into two groups: the main group and the control group. Patients of the main group received instillations of “Oftalmoferon” 6-8 times a day and those of “Okomistin” qid, patients of the control group - instillations of “Oftalmoferon” 6-8 times a day as monotherapy. Results. Combined use of “Okomistin” and “Oftalmoferon” significantly decreases the time of clinical recovery, is well tolerated, and does not cause toxic and allergic reactions. Conclusion. Combined use of “Okomistin” and “Oftalmoferon” in comparison to “Oftalmoferon” as monotherapy is more effective, but necessitates the use of ophthalmic lubricants.

scholarly journals Comparative Analysis of Double and Trifocal IOL Implantation in Femtosecond Laser-Assisted Cataract Surgery

2019 ◽  
Vol 16 (1S) ◽  
pp. 68-73 ◽  
Author(s):  
O. I. Orenburkina
Keyword(s):  
Visual Acuity ◽  
Femtosecond Laser ◽  
Cataract Surgery ◽  
Average Distance ◽  
Clinical Results ◽  
Main Group ◽  
Intraocular Lenses ◽  
Control Group ◽  
Lighting Conditions ◽  
Near Visual Acuity

Purpose: to compare the clinical results of implantations of bi-and trifocal intraocular lenses (IOL) in femtosecond laser-assisted cataract surgery. Patients and methods. The article presents the results of the Acrysof IQ Panoptix trifocal lens implantations in 84 patients (112 eyes) — the main group and Acrysof IQ Restor bifocal IOL implantations in 52 patients (98 eyes) — the control group. All patients underwent femtosecond laser-assisted cataract surgery (FLACS). The following data were evaluated: uncorrected distance visual acuity (UCDVA) , uncorrected near visual acuity (30–45 cm) and at an average distance (50–70 cm) at discharge, after 14 days, 1 and 3 months after the surgery under photopic and mesopic lighting conditions. Postoperative refractometry data; the defocusing curve was performed in patients with a high UCDVA (0.9–1.0) monocularly under photopic conditions using standard optotypes 14 days after surgery; aberrometry indicators. Results. It was shown that both lenses provided high uncorrected distance and near visual acuity in photopic lighting conditions. At the same time, the Acrysof IQ Panoptix lens provided significantly better visual acuity at an intermediate distance and was more resistant to defocusing conditions. Refraction data: after 1 month, emmetropia was observed in 87 % of patients in the main group and in 85 % of control group, after 6 months — 92 and 89 % respectively. There were no significant differences in high order aberrations and total aberrations between patients of the compared groups. Conclusion. The use of the PanOptix trifocal lens made it possible to obtain maximum visual acuity at different distances, regardless of the level of illumination.

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