scholarly journals CONGENITAL TOXOPLASMOSIS. CLINICAL OBSERVATION

2020 ◽  
Vol 18 (5) ◽  
pp. 611-618
Author(s):  
A. I. Paltseva ◽  
◽  
V. L. Zverko ◽  
L. N. Sinitsa ◽  
S. M. Ponomarenko ◽  
...  

The article presents a review of the literature and clinical observation of a newborn with congenital toxoplasmosis. The difficulties of diagnosing the asymptomatic form of congenital toxoplasmosis in the early neonatal period in one of the twins of a newborn are discussed. The authors note that a careful collection of antenatal history (nutritional culture, contact with a feline), analysis of the patient’s physical development, correct interpretation of the clinical manifestation, data from laboratory research methods and clinical alertness for congenital TORCH complex infection will contribute to the early diagnosis of the disease. Timely etiopathogenetic therapy will allow for effective treatment and early prevention of disabling complications in a patient.

2019 ◽  
Vol 19 (2) ◽  
pp. e271-e275 ◽  
Author(s):  
Sara Tanini ◽  
Alessandra D. Fisher ◽  
Icro Meattini ◽  
Simonetta Bianchi ◽  
Jiska Ristori ◽  
...  

PEDIATRICS ◽  
1964 ◽  
Vol 34 (5) ◽  
pp. 744-745
Author(s):  
RUSTIN MCINTOSH

This is a gem of a book—small, compact, sparkling, a bit expensive for its size. It reflects the growing interest in congenital defects and the realization that early identification is the key to successful correction in an increasing number and variety of anomalies. The author, consultant pediatrician to Alder Hey and Olive Mount Children's Hospitals in Liverpool, addresses himself to obstetrician and pediatrician alike, placing special emphasis on the conditions which can be recognized or suspected during the four weeks preceding birth and in the neonatal period.


PEDIATRICS ◽  
1957 ◽  
Vol 20 (1) ◽  
pp. 98-100
Author(s):  
Stanley E. Crawford

THE PURPOSE of this paper is to report a recent case of an umbilical polyp and intestinal obstruction during the neonatal period. Umbilical polyps are rare. When present, they may be associated with Meckel's diverticulum because both are remnants of the omphalomesenteric duct. The presence of the visible polyp may give an external clue to otherwise obscure intraabdominal symptoms. A review of the literature earlier than 1916 is well summarized in a book by Thomas Cullen. This unusual volume lists six cases of umbilical polyp accompanied by other pathologic complications of Meckel's diverticulum. This author stressed that in these cases it should be pointed out to either the patient or his parents that possible intra-abdominal duct remnants may, at any time, give rise to symptoms such as intestinal obstruction. Penberthy and Benson reported a 9-year-old male with an umbilical polyp which had been present since birth and was without discharge. This youngster died following operation for intestinal obstruction due to volvulus about the diverticulum and its fibrous connection with the umbilical polyp. These authors pleaded for early elective operations in these cases prior to such complications. Gross gave other reasons for observation, and exploration at a reasonably early age, if a Meckel's diverticulum is suspected. Peritonitis from a ruptured Meckel's diverticulum is peculiarly dangerous; in young children the protecting omentum is inadequate and the migrating nature of the anomaly adds to the danger. Fluid from perforation of a diverticulum is usually of greater volume than that found in appendiceal rupture and abscess.


1970 ◽  
Vol 10 (4) ◽  
pp. 289-292
Author(s):  
F Sharmin ◽  
F Begum ◽  
T Parveen ◽  
SF Khatun ◽  
W Fatima

A patient at her 38+ wks of pregnancy as a ultrasonographically diagnosed case of conjoined twin admitted in our department with ruptured membrane. Two live female babies joined at the chest were delivered by caesarean section. The parents refused a separation operation and the mother and the babies were discharged from hospital at 6th post natal day. A review of the literature suggests that early diagnosis by a combination of ultrasound and MRI is essential for management as it provides prognosis for viability and process of surgical separation and also the opportunity for early counseling of parents and termination if indicated. Key world: Conjoined twins; thoracopagus; prenatal diagnosis; separation procedure DOI: http://dx.doi.org/10.3329/bjms.v10i4.9504 BJMS 2011; 10 (4): 289-292


PEDIATRICS ◽  
1979 ◽  
Vol 63 (2) ◽  
pp. 285-285
Author(s):  
R. Riikonen

At the Children's Hospital, University of Helsinki, 205 children with infantile spasms who were born between 1960 and 1976 were studied in a search for the factors responsible. In 11 children (5%) the infantile spasms were possibly associated with cytomegalovirus (CMV) infection. The number may actually have been considerably higher, as no systematic search was made for CMV, especially in the early years. In four of the 11 children, the infection was probably congenital, and was the most likely cause of the spasms. One of the remaining seven children had congenital toxoplasmosis and the simultaneous CMV infection was probably also congenital. The children with congenital CMV infection exhibited severe clinical symptoms in the neonatal period or in early infancy. Two frequent symptoms were persistent tremor and meningoencephalitis. Later, all five children were severely mentally retarded and had spastic tetraplegia and small heads; three of them had optic atrophy and were blind. In the other six children, the CMV infection was probably acquired, the clinical symptoms being less severe, and the spasms may have been caused by another factor. In two of the 11 cases, immunosuppressive therapy (ACTH treatment generally given for infantile spasms) seems to have caused a fulminant CMV infection. Two children with CMV infection still show signs of a slow virus infection in the central nervous system many years later.


1974 ◽  
Vol 83 (6) ◽  
pp. 725-728 ◽  
Author(s):  
James S. Simpson ◽  
Tibor Ruff ◽  
Blair Fearon

Traumatic perforation of the esophagus during esophagoscopy is an ever present danger that can have long lasting or lethal effects. All are agreed on the need for early diagnosis. The question is often asked whether treatment should be nonoperative or operative. The results of management in this series of 21 patients support the opinions of those who advocate early adequate drainage of the mediastinum by means of mediastinotomy or thoracotomy, with support by antibiotic therapy, nothing by mouth and careful observation, if a large perforation is present. In minor perforations conservative treatment alone may suffice but should be accompanied by alert clinical observation.


1980 ◽  
Vol 58 (6) ◽  
pp. 1090-1099 ◽  
Author(s):  
Jean Ferron

A detailed analysis of the behavioural development of the red squirrel (Tamiasciurus hudsonicus) from birth to weaning is presented. For each behaviour pattern, the earliest and latest ages of emergence in a series of 14 young (from three litters) were registered and a mean was calculated. A review of the principal events of physical development is given first. The ontogeny of behaviour is then considered under five headings: locomotion, alertness and exploration, feeding, comfort, and social interactions. In the discussion, a general analysis of the development of behaviour with regard to the different periods of ontogeny (neonatal period, transition period, and socialization period) and the two leading events of the early life of the red squirrel (emergence from the nest and weaning) is given. It appears that the young are equipped with a minimum of behaviour patterns during the period of nest confinement and that close to emergence, a series of new behaviours come into effect with the exception of locomotion, which evolves gradually and regularly during ontogeny.


2020 ◽  
Vol 2020 ◽  
pp. 1-11
Author(s):  
Nicole Pini ◽  
Martina Ceccoli ◽  
Patrizia Bergonzini ◽  
Lorenzo Iughetti

Background and Objective. Grisel’s syndrome is a rare syndrome characterized by nontraumatic rotatory subluxation of the atlantoaxial joint. It usually affects children and typically presents with torticollis after ear, nose, and throat (ENT) surgery or head and neck infections. In the pediatric literature, there is only a small amount of available data; moreover, no systematic review has been previously done with focus on the pediatric population. We report our experience of two cases, and we provide a systematic review on Grisel’s syndrome in children in order to offer a deeper insight about its clinical presentation, its current diagnosis, and principles of treatment. Case Reports and Review. We describe two boys of 9 and 8 years old, who developed atlantoaxial subluxation after adenoidectomy. Considering the early diagnosis, a conservative treatment was chosen, with no recurrence and no sequelae at follow-up. We identified 114 case reports, of which 90 describe children, for a total of 171 pediatric patients. Of the 154 cases in which cause was reported, 59.7% presented a head and neck infection and 35.7% had previous head and neck surgery. There is no sex prevalence (49.7% males versus 50.2% females). Mean delay in diagnosis is 33 days. Eight % of the patients had neurological impairment of the 165 cases which mentioned treatment, 96% underwent a conservative treatment, of whom the 8.8% recurred with the need of surgery. As a whole, 12% underwent surgery as a first- or second-line treatment. 3 6% of the patients whose follow-up was reported developed a sequela, minor limitation of neck movement being the most frequent. Conclusion. Grisel’s syndrome should be suspected in children with painful unresponsive torticollis following ENT procedures or head and neck inflammation. CT scan with 3D reconstruction is the gold standard for diagnosis, allowing the identification of the subluxation and the classification according to the Fielding–Hawkins grading system. Surgical treatment is indicated in case of high-grade instability or failure of conservative treatment. Review of the literature shows how early diagnosis based on clinical and radiological evaluation is crucial in order to avoid surgical treatment and neurologic sequelae.


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