Intermittent fasting

2021 ◽  
pp. 116-120
Author(s):  
А.А. Пальцын ◽  
Н.Б. Свиридкина
Keyword(s):  
Food Consumption ◽  
Therapeutic Efficacy ◽  
Metabolic Disorders ◽  
Overweight And Obesity ◽  
Intermittent Fasting ◽  
Fasting Period ◽  
Prevention And Treatment

Интервальное голодание (intermittent fasting) - метод профилактики и лечения людей с самой распространенной сегодня патологией: избыточной массой тела и ожирением. Особую актуальность проблеме создает тот факт, что некрасивое и осложняющее жизнь ожирение - маркер расстройства метаболизма, предрасполагающего к развитию многих неинфекционных пандемий современного человечества. Интервальное голодание осуществляется ежесуточным полным отказом от еды на срок не менее 12 часов, - соотношение периодов голодания и приема пищи 12 ч : 12 ч. Увеличение периода голодания, например, 18 ч : 6 ч повышает профилактическую и лечебную эффективность интервального голодания. Intermittent fasting is a method for prevention and treatment of the currently most common pathology, overweight and obesity. Of particular relevance is the fact that ugly and life-complicating obesity is a marker of metabolic disorders that predispose people to many noninfectious pandemics. The interval fasting is performed by daily complete refraining from food for at least 12 hours with a 12h:12h ratio of fasting and food consumption periods. Increasing the fasting period, for example to 18h:6h, enhances the preventive and therapeutic efficacy of intermittent fasting.

scholarly journals Prevalence of Metabolic Syndrome in Children and Adolescents with Type 1 Diabetes Mellitus and Possibilities of Prevention and Treatment: A Systematic Review

Nutrients ◽  
2021 ◽  
Vol 13 (6) ◽  
pp. 1782
Author(s):  
Monika Grabia ◽  
Renata Markiewicz-Żukowska ◽  
Katarzyna Socha
Keyword(s):  
Systematic Review ◽  
Metabolic Syndrome ◽  
Type 1 Diabetes ◽  
Children And Adolescents ◽  
Treatment Options ◽  
Overweight And Obesity ◽  
Excess Body Weight ◽  
Healthy Population ◽  
Prevention And Treatment

Overweight and obesity are an increasingly common problem, not only among the healthy population, but also in adolescents with type 1 diabetes (T1DM). Excess body weight is related to many cardiometabolic complications as well as a high risk of metabolic syndrome (MetS). The purpose of this systematic review is to provide a concise and critical overview of the prevalence of MetS in children and adolescents with T1DM and, ultimately, to discuss prevention and treatment options. The study was conducted in accordance with PRISMA guidelines. This review shows that, apart from the growing percentage of overweight and obese children and adolescents with T1DM (on average 20.1% and 9.5%, respectively), the problem of the increasing incidence of MetS (range from 3.2 to 29.9%, depending on the criteria used) is one of the most important phenomena of our time. One of the methods of prevention and treatment is a combined approach: changing eating habits and lifestyle, but there are also reports about the beneficial effects of the gut microflora.

scholarly journals Availability of ultra-processed food associated with health outcomes: a systematic review

2020 ◽  
Vol 30 (Supplement_5) ◽  
Author(s):  
T Pereira de Araújo ◽  
M Moraes ◽  
V Magalhães ◽  
C Afonso ◽  
S Rodrigues
Keyword(s):  
Risk Factors ◽  
Health Outcomes ◽  
Food Consumption ◽  
Food Availability ◽  
Overweight And Obesity ◽  
Noncommunicable Diseases ◽  
Research Association ◽  
Processed Food ◽  
Household Budget ◽  
Household Budget Surveys

Abstract Background Ultra-processed food (UPF) consumption increases worldwide, which can be harm to population's health. To establish associations between UPF and health outcomes, food consumption can be assessed individually or by using availability data, such as purchase lists or household budget surveys. The aim of this review was to search for studies on the availability of UPF related with mortality and morbidity from noncommunicable diseases or their risk factors. Methods PRISMA guideline was used. Searches were performed on PubMED, EBSCO, Scopus and Web of Science on December 2019. Search strategy included terms related with exposure (UPF) and outcomes (mortality or morbidity from noncommunicable diseases and their risk factors). Studies were selected based on the title and abstracts. Full texts were screened for eligibility and the snowballing method was used to find other relevant studies. To be based on UPF availability data and its relation with health outcomes were the inclusion criteria. Studies that assessed only food consumption at an individual level and did not present health outcome were excluded. Selection was conducted by two reviewers and a third helped when disagreement occurred. Results After duplicates removal, 560 records were analyzed. From the 11 eligible studies, 55% were conducted in more than one country. Others were performed in Brazil (27%), Guatemala (9%) and Sweden (9%). Studies were ecological (64%), cross-sectional (27%) and longitudinal (9%). All had representative samples, 45.5% were national samples, and the others were from particular population subgroups. In all studies, the only health outcomes that showed positive association with UPF availability were overweight and obesity prevalence. Conclusions Studies relating ultra-processed food availability and health outcomes are mainly focused on overweight and obesity. It is thus necessary to further explore the relationship between UPF availability and other health outcomes. Key messages It is necessary to further research association between ultra-processed food availability and other health outcomes, such as morbidity and mortality from cardiovascular diseases, diabetes or cancer. Purchase lists or household budget surveys are an important source of food availability data and can be used to relate the consumption of ultra-processed foods to health outcomes.

scholarly journals eHealth interventions for the prevention and treatment of overweight and obesity in adults: a systematic review with meta-analysis

2015 ◽  
Vol 16 (5) ◽  
pp. 376-392 ◽  
Author(s):  
M. J. Hutchesson ◽  
M. E. Rollo ◽  
R. Krukowski ◽  
L. Ells ◽  
J. Harvey ◽  
...  
Keyword(s):  
Systematic Review ◽  
Meta Analysis ◽  
Overweight And Obesity ◽  
Prevention And Treatment

scholarly journals The tissue origin of human mesenchymal stem cells dictates their therapeutic efficacy on glucose and lipid metabolic disorders in type II diabetic mice

2021 ◽  
Vol 12 (1) ◽  
Author(s):  
Yinzhong Ma ◽  
Lisha Wang ◽  
Shilun Yang ◽  
Dongyu Liu ◽  
Yi Zeng ◽  
...  
Keyword(s):  
Stem Cells ◽  
Mesenchymal Stem Cells ◽  
Therapeutic Efficacy ◽  
Metabolic Disorders ◽  
Human Mscs ◽  
Dependent Manner ◽  
Type Ii ◽  
Diabetic Mice ◽  
Histological Lesion ◽  
Insulin Levels

Abstract Background The therapeutic efficacy of mesenchymal stem cells (MSCs) of different tissue origins on metabolic disorders can be varied in many ways but remains poorly defined. Here we report a comprehensive comparison of human MSCs derived from umbilical cord Wharton’s jelly (UC-MSCs), dental pulp (PU-MSCs), and adipose tissue (AD-MSCs) on the treatment of glucose and lipid metabolic disorders in type II diabetic mice. Methods Fourteen-to-fifteen-week-old male C57BL/6 db/db mice were intravenously administered with human UC-MSCs, PU-MSCs, and AD-MSCs at various doses or vehicle control once every 2 weeks for 6 weeks. Metformin (MET) was given orally to animals in a separate group once a day at weeks 4 to 6 as a positive control. Body weight, blood glucose, and insulin levels were measured every week. Glucose tolerance tests (GTT) and insulin tolerance tests (ITT) were performed every 2 weeks. All the animals were sacrificed at week 6 and the blood and liver tissues were collected for biochemical and histological examinations. Results UC-MSCs showed the strongest efficacy in reducing fasting glucose levels, increasing fasting insulin levels, and improving GTT and ITT in a dose-dependent manner, whereas PU-MSCs showed an intermediate efficacy and AD-MSCs showed the least efficacy on these parameters. Moreover, UC-MSCs also reduced the serum low-density lipoprotein cholesterol (LDL-C) levels with the most prominent potency and AD-MSCs had only very weak effect on LDL-C. In contrast, AD-MSCs substantially reduced the lipid content and histological lesion of liver and accompanying biomarkers of liver injury such as serum aspartate transaminase (AST) and alanine aminotransferase (ALT) levels, whereas UC-MSCs and PU-MSCs displayed no or modest effects on these parameters, respectively. Conclusions Taken together, our results demonstrated that MSCs of different tissue origins can confer substantially different therapeutic efficacy in ameliorating glucose and lipid metabolic disorders in type II diabetes. MSCs with different therapeutic characteristics could be selected according to the purpose of the treatment in the future clinical practice.

scholarly journals Consumption of ultra-processed foods and the risk of overweight and obesity, and weight trajectories in the French cohort NutriNet-Santé

2020 ◽  
Vol 79 (OCE2) ◽  
Author(s):  
Bernard Srour ◽  
Marie Beslay ◽  
Caroline Méjean ◽  
Benjamin Allès ◽  
Thibault Fiolet ◽  
...  
Keyword(s):  
Food Intake ◽  
Confidence Interval ◽  
Prospective Study ◽  
Food Consumption ◽  
Overweight And Obesity ◽  
Processed Foods ◽  
Processed Food ◽  
Weight Trajectories ◽  
Incident Cases

AbstractIntroductionPrevious epidemiological studies have found associations between the consumption of ultra-processed foods and the risk of obesity-related outcomes, such as post-menopausal breast cancer, cardiovascular diseases, hypertension and mortality. However, only one Spanish prospective study has explored the associations between the consumption of ultra-processed foods and the risk of overweight and obesity. The aim of this study is to investigate the associations between ultra-processed food consumption and the risk of overweight and obesity, as well as the associations between ultra-processed food consumption and weight trajectories, in middle-aged adults included in the French large scale NutriNet-Santé cohort.MethodsOverall, 110260 participants aged at least 18 years from the French NutriNet-Santé cohort (2009–2019) were included. Dietary intakes were collected using repeated 24 hour dietary records, merged with a food composition database of 3300 different products. These were categorized according to their degree of processing by the NOVA classification. Associations between ultra-processed food intake and risks of overweight and obesity were assessed using multivariable Cox proportional hazard models. Associations between ultra-processed food intake and weight trajectories were assessed using multivariable linear mixed models for repeated measures with random slope and intercept. Models were adjusted for known risk factors (sociodemographic, lifestyle, and nutritional factors).ResultsUltra-processed food intake was associated with a higher risk of overweight (n = 7063 incident cases; hazard ratio for an absolute increment of 10 in the percentage of ultra-processed foods in the diet = 1.11 (95% confidence interval 1.08 to 1.14); P < 0.0001, median follow-up: 4.1y, 260304 person-years) and obesity (n = 3066 incident cases; HR = 1.09 (95% confidence interval 1.05 to 1.13); P < 0.0001, median follow-up: 8.0y 365344 person-years). Higher consumers of ultra-processed foods (4th quartile) were more likely to present an increase in body mass index over time (change of BMI/time-unit in Q4 vs Q1 = 0.04, P < 0.0001). These results remained statistically significant after adjustment for several markers of the nutritional quality of the diet (fruits and vegetables and sugary drinks consumption, intakes of saturated fatty acids, sodium, sugar, dietary fiber or Healthy/Western patterns derived by principal component analysis) and after a large range of sensitivity analyses.ConclusionIn this large observational prospective study, higher consumption of ultra-processed foods in the diet was associated with a higher risk of overweight and obesity. Public health authorities in several countries recently started to recommend privileging unprocessed/minimally processed foods and limiting ultra-processed food consumption.

scholarly journals A cross-sectional study to determine the prevalence of obesity, overweight and weight awareness among the students of a private medical college in Khulna

Mediscope ◽  
2020 ◽  
Vol 7 (2) ◽  
pp. 103-107
Author(s):  
Md Abul Hasanat ◽  
Silvia Paroi ◽  
Arifa Begum ◽  
Umme Salma ◽  
Syeda Farzana Yeasmin
Keyword(s):  
Medical Students ◽  
Food Consumption ◽  
Fast Food ◽  
Cross Sectional Study ◽  
Overweight And Obesity ◽  
Sectional Study ◽  
Cross Sectional ◽  
Medical College ◽  
Fast Food Consumption ◽  
Prevalence Of Obesity

Background: Medical education is stressful throughout the whole course. Due to the medical curriculum and the examination pattern leads to psychological stress. Stressful condition leads to irregularity in diet, frequent fast food consumption & lack of exercise, each being considered as an important risk factor leading to overweight and obesity. Hence, this study was undertaken to determine the prevalence of obesity, overweight and weight awareness among the medical students. Objectives: Determination of BMI status of undergraduate medical students to evaluate their weight awareness, prevalence of overweight and obesity and also find out the relationship of the following risk factors with obesity & overweight; i) Opinion about self-image, ii) Physical activity and iii) Frequency of fast food consumption. Methods: A descriptive cross sectional study was conducted on 131 preclinical medical students of Ad-din Akij Medical College, Khulna from January 2018 to April 2018. Height and weight of 131 preclinical students were measured and Body Mass Index was calculated and categorized according to WHO criteria. Results: Out of 131 students 62% come under normal weight category, 21% come under overweight category, 10% come under obese category and 7% come under underweight category. Conclusion: Overweight is a rising problem among the medical students. Sedentary life style and frequency of fast food consumption was high among the overweight and obese students. This study itself created awareness about their weight and promote physical activity among the medical students. Mediscope Vol. 7, No. 2: July 2020, Page 103-107

scholarly journals Adiponutrin as a Marker of Metabolic Disorders in Patients with Hypertension with Overweight and Obesity

2021 ◽  
Vol 6 (2) ◽  
pp. 77-86
Author(s):  
P. G. Kravchun ◽  
◽  
O. I. Kadykova ◽  
U. S. Herasymchuk
Keyword(s):  
Enzyme Immunoassay ◽  
Carbohydrate Metabolism ◽  
Metabolic Disorders ◽  
Low Density Lipoprotein ◽  
Density Lipoprotein ◽  
High Body Mass Index ◽  
Vascular Cognitive Impairment ◽  
Arterial Disease ◽  
Overweight And Obesity ◽  
Control Group

Hypertension is a leading risk factor for coronary heart disease, stroke, peripheral arterial disease, kidney disease, vascular cognitive impairment, and mortality worldwide. Obesity in combination with hypertension continues to attract considerable attention from scientists. Despite the presence of experimental and clinical evidence of mutual burdening of hypertension and obesity, the mechanisms of formation of pathophysiological consequences of such a combination remain insufficiently defined. That is why in recent years an important role is given to the adiponutrin protein. The purpose of the study is to assess the nature of the relationship between adiponutrin levels and lipid and carbohydrate metabolism depending on the duration and degree of hypertension and the degree of obesity in patients with this comorbid pathology. Material and methods. The study included 107 patients with hypertension who were hospitalized in the cardiology department of Municipal noncommercial enterprise "Kharkiv City Clinical Hospital No.27" of Kharkiv municipal council. The age of patients ranged from 32 to 79 years (mean age was 58.6±9.88), who had not previously received regular antihypertensive therapy. The control group consisted of 20 age- and sex-appropriate healthy individuals. The level of adiponutrin was determined in 58 patients with hypertension of the 1st - 3rd degrees, aged from 32 to 79 years (mean age was 57.5±10.11 years), while hypertension of the 1st degree was diagnosed in 12 (20.7%) patients, hypertension of the 2nd degree - in 16 (27.6%), and hypertension of the 3rd degree - in 30 (51.7%) of the examined patients. Blood pressure was measured in patients in a sitting position after 5 minutes of rest, anthropometric measurements were performed, lipid profile and indicators of carbohydrate metabolism were evaluated, adiponutrin levels (pg/mL) were determined by enzyme immunoassay method using The RayBio® Adiponutrin Enzyme Immunoassay (EIA) Kit, (USA). Results and discussion. In all groups of patients with hypertension with overweight and obesity, adiponutrin levels were significantly elevated, and lipid and carbohydrate profiles tended to increase. Significant direct correlations were found between adiponutrine and triglycerides, with very low-density lipoprotein cholesterol of a moderate nature, and draws attention with a very high body mass index. In considering the differences in adiponutrin levels depending on gender, it was found that men have higher adiponutrin levels than women. Conclusion. Thus, we have the opportunity to consider adiponutrin as a marker of metabolic disorders

scholarly journals Overweight and Obesity-related Metabolic Disorders in Hospital Employees

2006 ◽  
Vol 105 (1) ◽  
pp. 56-63 ◽  
Author(s):  
Lee-Ching Hwang ◽  
Cheng-Ho Tsai ◽  
Tony Hsiu-Hsi Chen
Keyword(s):  
Metabolic Disorders ◽  
Overweight And Obesity ◽  
Hospital Employees
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