Clinical pharmacist interventions in post stroke follow up patients in tertiary care hospital on coastal region

Author(s):  
Prakash A ◽  
Kalyan Rao B ◽  
Sujitha Sri K ◽  
Lakshman Naik R ◽  
Shaik Shahin Kouser ◽  
...  

Stroke is basically a medical condition where there is low blood flow to the brain and thus results in cell death. It remains the second most common cause of death. Stroke patients also have different comorbidities on an average where they are prescribed with 6-10 medicines. This increase the chances for drug-related problems (DRPs) and adverse drug events (ADEs) or adverse drug reactions (ADRs) and the interventions found during the follow up of stroke patients. Several studies finding of interventions in stroke patients and reconciliation are ways to reduce ADRs and improve medication use safety. Interventions and medical reconciliation (MR) address a wide array of potential medication-related issues, which is carefully planned that may be done by pharmacist or doctor or professional (or) physician. Here the aim was to access the impact of interventions which includes medications reconciliation and counselling of stroke patients and also identification and categorization of DRPs. Polypharmacy causing DRPs was statistically significant in all the regions inappropriate drug selection (2.85%), and dose selection (2.85%) was the primary cause of DRPs 85% partially solved. Epidemiologically of all the three regions (GNT, VIJ, RJY) in the total study population. Males are more affected than females. Majority of comorbidities like HTN(70.05%), and DM(47.01%)were in leading role causing stroke absorbed during interventions. Leaflet & patient counselling had prominent role in conducting medical reconciliation. Other health care professionals systematically find, differentiate & report interventions like (DRPs, ADRs, and causes).

2014 ◽  
Vol 32 (3_suppl) ◽  
pp. 665-665
Author(s):  
Inmaculada Gallego Jimenez ◽  
Amelia Lopez Ladron ◽  
David Morales Pancorbo ◽  
Eva Fernandez Parra ◽  
Maria Rodriguez de la Borbolla ◽  
...  

665 Background: Bevacizumab, a humanized antibody against the molecular target endotelial growth factor VEGF-A, has incorporated to the standard of care of metastatic colon-rectal cancer (mCRC). A recent study has suggested that the left colon localization of the primary tumor may be a factor associated with a poorer survival in individuals treated against mCRC with bevacizumab including chemotherapy. Our objective was to analyze the impact of the localization of the primary tumor on the survival of patients with mCRC treated with bevacizumab. Methods: Prospective cohort study conducted in a tertiary-care hospital in Spain. Twenty-nine consecutive patients with mCRC who started a first-line therapy including bevacizumab were included. Patients were followed up until death, lost to follow-up or the censoring date (31th August, 2013). The primary end-point of the study was death from any cause. Predictors of survival, including the localization of the primary tumor, were assessed. Results: The median (Q1-Q3) age was 59 (52-67) years and 13 (45%) patients were male. Chemotherapy scheme was XELOX in 13 (45%) patients, FOLFOX in 8 (28%), FOLFIRI in 5 (17%), XELIRI in 2 (7%) and capecitabine in 1 (3%) patient. The localization of the primary tumor were distributed as follows: rectum in 6 (21%), sigmoid colon in 9 (31%), left colon in 9 (31%) and right colon in 5 (17%) patients. After a median (Q1-Q3) follow-up of 29 (13-41) months, 19 (66%) patients died. There were no patients lost to the follow-up. The mean (SD) survival in patients with left colon cancer was 25 (8) months whereas it was 47 (7) months in the remaining population (p = 0.1). The low sample size precluded to perform reliable multivariate analyses. Conclusions: Our study suggests that left colon localization of the primary tumor may have a worse prognosis in patients with mCRC treated with bevacizumab. Although no statistically significant differences have been observed, this fact may have been a consequence of the limited power of the analysed sample. Collaborative studies should be perfomed in order to clarify this issue.


2015 ◽  
Vol 3 (1) ◽  
pp. 17-20
Author(s):  
Elpreda M. Victor ◽  
Evangelin M. Vasanth ◽  
Mary Thankappan ◽  
Srinithya Raghavan ◽  
Amit Dadhich ◽  
...  

2010 ◽  
Vol 24 (9) ◽  
pp. 543-546 ◽  
Author(s):  
Greg Rosenfeld ◽  
Darin Krygier ◽  
Robert A Enns ◽  
Janakie Singham ◽  
Holly Wiesinger ◽  
...  

BACKGROUND: For patients requiring colonoscopy while admitted to hospital, achieving adequate cleansing of the colon is often difficult.OBJECTIVES: To assess the impact of patient education, in the form of both counselling and written instructions, on bowel cleanliness at colonoscopy.METHODS: A total of 38 inpatients at a tertiary care hospital in Vancouver, British Columbia, who were referred to the gastroenterology service for colonoscopy were enrolled in the present study. Sixteen patients were randomly assigned to the intervention group, while 22 patients comprised the control group. Both groups received a clear liquid diet and 4 L of a commercially available bowel preparation. The intervention group also received a brief counselling session and written instructions outlining the methods and rationale for bowel preparation before colonoscopy. Bowel cleanliness was assessed by the endoscopist using a five-point rating scale.RESULTS: The two groups were similar with respect to demographics, the indication for colonoscopy and findings at colonoscopy. The median bowel cleanliness scores in the control group and the enhanced-instruction group were 3.0 and 2.0, respectively (P=0.001).CONCLUSION: Patient counselling and written instructions are inexpensive, safe and simple interventions. Such interventions are an effective means of optimizing colonoscopy preparation in the inpatient setting.


Blood ◽  
2020 ◽  
Vol 136 (Supplement 1) ◽  
pp. 33-34
Author(s):  
Ruth Namazzi ◽  
Robert Opoka ◽  
Andrea L Conroy ◽  
Dibyadyuti Datta ◽  
Micheal Goings ◽  
...  

COVID-19 and its prevention has put considerable strain on health care systems in low and middle-income countries (LMIC). In Uganda, a national lockdown was declared on March 18, 2020, in response to COVID-19 pandemic and concern of spread of cases without aggressive measures to prevent spread. The lockdown consisted of closure of all offices except essential ones, orders to stay at home unless an emergency occurred, school closure, a ban on all meetings of more than 10 people, a ban on public and private transport, closing down of all shops, malls, restaurants, places of worship and other facilities in which group meetings might occur, keeping a distance of at least 2 metres from other people in public places and a 7:00 p.m. to 6:30 a.m. curfew. Hospitals however remained open and operational. We describe the impact of the lockdown in Uganda in response to the COVID-19 pandemic on the morbidity and mortality in children with sickle cell anaemia (SCA) at a tertiary hospital in Uganda. The number of clinic visits for SCA related complications and death were compared in the pre-lockdown (November 2019 to February 2020) and during COVID-19 lockdown periods (March 2020 to June 2020) in children aged 1- 4.99 years enrolled in a SCA research study [Zinc for Infection Prevention in Sickle cell anaemia (NCT03528434)] at Jinja Hospital, Uganda. In the study, children with SCA are asked to return to the hospital for evaluation whenever they are unwell. Follow up phone calls are made to ascertain the wellbeing of the children and identify any who are unable to come to the hospital. During the lockdown, follow up calls continued and facilitation was provided for caregivers to bring any child who was unwell to the hospital for evaluation. A total of 238 children with a mean (standard deviation) age of 2.7(1.1) years were enrolled and were being followed up when the pandemic started. The incidence of hospital sick visits pre-lockdown and during the lockdown period was 7.7 vs 4.0 person-year, (p= <0.0001). Incidence of hospitalization, pain crises, severe anaemia, or malaria were all higher in the pre-lockdown period than during the lockdown period, 2.4 vs.1.0, 1.8 vs. 0.7, 0.7 vs. 0.4, 0.6 vs. 0.2 and per person year respectively (all p values < 0.01). There were no deaths during the lockdown period compared to 1 death in the pre-lockdown period. Less than 1000 cases of COVID-19 were reported nationally in this period, and none of the study children had known COVID-19 infection, though testing capacity for this was limited. In this cohort of children with SCA, hospitalization and morbidity from SCA-related complications and malaria were are significantly lower during a lockdown period for COVID-19 pandemic than before the lockdown. Reduced access to hospital care is unlikely to explain these findings, as sick children still received care at the hospital, and there was no increase in mortality. Reduced interaction with peers because of the lockdown and social distancing, leading to fewer infections that may trigger SCA-complications, may explain the reduced incidence of SCA complications in this population during the COVID-19 lockdown period in Uganda. Disclosures No relevant conflicts of interest to declare.


2021 ◽  
pp. 13-16
Author(s):  
Dhruvina Jaykumar Suru ◽  
Shivani Milind Pandirkar ◽  
Shailaja Sandeep Jaywant

Greater number of stroke survivors suffer from disability and extended years of care is required to be undertaken by family members which adds burden to caregivers daily life. Thus burden on caregivers needs attention to study the impact of stroke .Till now, scarce literature is found to study the correlation of severity of stroke and burden on caregivers. This study was done to nd the correlation of severity of stroke with functional independence and also intends to nd the correlation of Functional dependency with the caregivers burden& severity of stroke with caregivers burden in acute stroke patients Patients admitted in the tertiary care hospital of metropolitan city in Maharashtra with the Acute stroke within 48 hours of onset were included in study , on 3rd day after stroke/admission to hospital. National Institutes Of Health Stroke Scale ( NIHSS), Barthel Index (BI), Burden Scale For Family Caregivers (BSFC), were used to gather information from 100 stroke patients admitted in hospital wards. Study showed strong negative correlation of -0.705 between NIHSS and BI, Barthel index correlation with caregiver burden score shows moderate negative correlation of – 0.482, NIH scale score correlation with caregiver burden score shows moderate positive correlation of 0.59. Thus stroke severity affects negatively on functional independence. caregivers have reported moderate burden due to dependance of patient. stroke severity has positive impact on caregivers burden. Further research in various stages of Stroke recovery on caregivers burden and functional independence level is recommended


2018 ◽  
Vol 6 (1) ◽  
pp. 15
Author(s):  
Vivek Parasher ◽  
Gaurav Dadhich ◽  
Rahul Khatri ◽  
Mansi Sharma

Background: Good nutrition, particularly in the first three years of life, is important in establishing and maintaining a good foundation that has implications on a child’s future physical and mental health. The present study has been undertaken to study the “Impact of the nutritional and immunization services on the children between 6 months to 3 years,” with special emphasis to identify moderate acute malnutrition (MAM) and severe acute malnutrition (SAM) cases.Methods: This observational study was conducted from August 2017 to July 2018 in department of paediatrics at pacific institute of medical science included 400 cases age between 6 months to 3 years.Results: Incidence of SAM and MAM is 7.5% and 30.75 % respectively. Female predominance was seen in SAM and MAM i.e. 53.4% and 54.6% respectively. Significant association of under-nutrition was found with LBW (p<0.05), not giving exclusive breast feeding up to 6 months of life (p<0.05) and, Low socioeconomic status (p<0.001). Higher numbers of females were unvaccinated.Conclusions: Despite introduction of various national programs at different levels for improvement of maternal and child health, we still have significant number of children who are undernourished and unimmunized. Children are future of our nation and their health is of paramount importance. It can only be achieved with strong political will, active participation of community and by increase commitment of health care professionals. We need to start from birth, institutional delivery, exclusive breast feeding, immunization, and timely introduction of complementary feeds, marriages at appropriate age, proper antenatal visits and birth spacing. 


Author(s):  
Juna Ann Thomas ◽  
Kakani Sai Snigdha ◽  
Preethy Mathew Karanath ◽  
Ann Mary Swaroop

Objective: Hypertension is a leading cause of death and disability worldwide and proper assessment of knowledge, attitude, and practice (KAP) factors are helpful in its management. Our aim was to assess the knowledge, attitude, and practice among hypertensive patients and the impact of patient counselling on the same.Methods: A prospective study was conducted among hypertensive patients from November 2015 to April 2016. Suitably designed and validated KAP questionnaire was used to evaluate the baseline KAP score. Patient information leaflets were provided after counselling. After 3 mo patients were followed up and their KAP scores were reassessed and data were analysed.Results: Before the intervention, the mean score±SD of knowledge, attitude, and practice were 11.76(SD±4.58); 5.14(SD±2.13); 9.26(SD±1.66) which increased to 14.29(SD±2.95); 5.74(SD±1.39); 10.32(SD±1.33) respectively after the intervention.Conclusion: Our study suggests that pharmacist mediated counselling plays a vital role in improving patients’ knowledge, attitude, and practice towards the disease management


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