scholarly journals Determination of transverse diameter and longitudinal axis in patients with cholecystitis and cholelithiasis by computed tomography to rule out gallbladder carcinoma

2020 ◽  
Vol 11 (4) ◽  
pp. 5643-5649
Author(s):  
Vishram Singh ◽  
Durgesh Singh ◽  
Ashutosh Tandon ◽  
Yogesh Yadav ◽  
Richa Tiwari
Keyword(s):  
Computed Tomography ◽  
Sensitivity And Specificity ◽  
Gallbladder Carcinoma ◽  
Longitudinal Axis ◽  
Transverse Diameter ◽  
The North ◽  
Specificity And Sensitivity ◽  
Abdominal Disease ◽  
Rule Out

The aim of the article is to the determination of transverse diameter and longitudinal axis in patients with cholecystitis and with the help of CT scan in the north Indian population for the estimation of epidemiology. Patients with cholecystitis and of ages between 17-80 years irrespective of gender were included in the study (cases). All patient's cases (100) and controls (100) were advised the night before that did not eat or drink. Control groups (Normal Gallbladder) were collected when patients are comprised of other abdominal disease diagnosed by computed tomography. The mean age of controls and cases was 47.24±11.57 and 45.20±16.22 years, respectively studied by computed tomography. More than half of cases (62%) and 50% of controls were females. The transverse diameter was significantly (p=0.0001) higher among cases (36.42±15.52 mm) than controls (24.12±9.11 mm) studied by computed tomography. Longitudinal axis was significantly (p=0.0001) higher among cases (33.23±14.73 mm) than controls (21.75±8.69) studied by computed tomography. Transverse diameter>25 correctly predicted cholecystitis and by CT in 38.5% cases with sensitivity and specificity of 77% (95%CI=68.8-85.2) and 74% (95%CI=55.7-74.3%) respectively. Longitudinal axis >25 correctly predicted cholecystitis and by CT in 34.5% cases with specificity and sensitivity of 69% (95%CI=59.9-78.1) and 71% (95%CI=62.1-79.9%) respectively. We concluded in this study, increased transverse diameter and longitudinal axis were observed. Good sensitivity and specificity of these two parameters were also found in predicting cholecystitis and by computed tomography. All such cases should be subjected to biopsy for examination to rule out the gallbladder carcinoma for better prognosis.

Odontogenic Sinusitis Index (OSI)

2021 ◽  
Vol 20 (5) ◽  
pp. 58-62
Author(s):  
S. Yu. Naumov ◽  
◽  
S. A. Artyushkin ◽  
O. A. Drozdova ◽  
M. A. Aflitonov ◽  
...  
Keyword(s):  
Data Analysis ◽  
Sensitivity And Specificity ◽  
Specificity And Sensitivity ◽  
Odontogenic Sinusitis ◽  
Simple Summation

The criteria for «odontogenic sinusitis» (OS) with the highest values of specificity and sensitivity were identified. An integral odontogenicity sinusitis index (OSI) was developed based on the identified criteria. To measure the sensitivity and specificity of the criteria, a group of 261 patients was selected (113 women (43.29%), 148 men (56.70%), the average age of the patients was 36 years), consisting of 150 known to have OS and 111 patients who were known to be without OS. As a result of data analysis, the values of sensitivity and specificity were obtained for all 13 criteria. Based on the sensitivity and specificity values, all criteria were combined into an odontogenicity sinusitis index (OSI) and divided into «minor» and «major». The “large” criteria were assigned a significance point of 2, and for the “small” criteria, a significance point of 1. The determination of the odontogenic nature of sinusitis was carried out by a simple summation of the points assigned to patients during the survey, examination, and analysis of CT criteria. An odontogenic cause of sinusitis is recognized if there is a minimum of 4 points of significance, for example, one “large” (2 points) and two “small” (1 point each) criteria. The general sensitivity of the integral OSI index was 93%, the general specificity was 94%. These rates are high enough that OSI can be used to determine the «odontogenic» nature of sinusitis.

scholarly journals Role of Ultrasound and Computed Tomography in the Evaluation of Gallbladder Malignancy

2017 ◽  
Vol 8 (2) ◽  
pp. 105-111
Author(s):  
Nusrat Ghafoor ◽  
Naffisa Abedin ◽  
AS Mohiuddin
Keyword(s):  
Computed Tomography ◽  
Gall Bladder ◽  
Ct Scan ◽  
Sensitivity And Specificity ◽  
Gallbladder Carcinoma ◽  
Bladder Carcinoma ◽  
Biliary Surgery ◽  
Gall Bladder Carcinoma ◽  
Additional Advantage ◽  
Thickened Wall

Background & objective: Ultrasonogram (USG) and computed tomography (CT) are often used in the evaluation of gall-bladder carcinoma. Thepresent study was conducted to determine the usefulness of USG and CT scan in diagnosing gallbladder carcinoma.Materials & Methods: This cross-sectional observational study was conducted at Department of Radiology and Imaging, BIRDEM in collaboration with the Departments of Hepato-biliary Surgery, and Histopathology of the same institute over a period of 3 years fromJuly 2004 to June 2006. A total of 42 patients (ranging from 40-80 years) were initially included on the basis of signs and symptoms of gallbladder carcinoma and underwent USG and CT scan for preoperative radiological diagnosis, its extension and operability. Following operation all the resected specimens were sent for histopathological evaluation. The diagnostic accuracies of USG and CT scan were then compared against histopathological diagnoses by using Kappa statistics.Result: In the present study, the mean age of the patients was 60 (range: 40-80) years with female preponderance. About 40% of the gall-bladder were contracted and reduced in size and 32.5% large and distended on USG examination, while 45% of the gall-bladder were contracted and reduced in size and 25% distended and large on CT examination. Approximately 40% had irregularly thickened wall and 21.2% diffusely thickened wall on USG and 30% of gallbladder wall were diffusely thickened and 45% irregularly thickened on CT scan. The present study showed hepatic parenchymal invasion to be 22.5% on USG and 42.5% on CT scan. The sensitivity and specificity of USG in diagnosing GB carcinoma were 93.9 and 71.4% respectively. Similarly, the sensitivity and specificity of CT scan in detecting GB carcinoma were 97.1 and 83.3% respectively. The test of agreement (Kappa test) revealed an almost 90% agreement between the two procedures meaning that the two diagnostic modalities are almost comparable in diagnosing gall bladder carcinoma (p<0.001).Conclusion: The study findings indicate that both USG and CT scan are ideal,non-invasive, safe imaging modalities for diagnosis of gallbladder carcinoma. CT scan has an additional advantage in defining the extension of the disease and involvement of surrounding structures including lymph nodes and hepatoduodenal ligament.Anwer Khan Modern Medical College Journal Vol. 8, No. 2: Jul 2017, P 105-111

scholarly journals Determination of Non-α1-Antichymotrypsin-complexed Prostate-specific Antigen as an Indirect Measurement of Free Prostate-specific Antigen: Analytical Performance and Diagnostic Accuracy

2003 ◽  
Vol 49 (6) ◽  
pp. 887-894 ◽  
Author(s):  
Sebastian Wesseling ◽  
Carsten Stephan ◽  
Axel Semjonow ◽  
Michael Lein ◽  
Brigitte Brux ◽  
...  
Keyword(s):  
Prostate Specific Antigen ◽  
Sensitivity And Specificity ◽  
Specific Antigen ◽  
Roc Curves ◽  
Indirect Measurement ◽  
Free Psa ◽  
Specificity And Sensitivity ◽  
Diagnostic Sensitivity And Specificity ◽  
Total Psa

Abstract Background: A new assay measures prostate-specific antigen (PSA) not complexed to α1-antichymotrypsin (nACT-PSA) after removing PSA complexed to ACT by use of anti-ACT antibodies. We evaluated nACT-PSA and its ratio to total PSA (tPSA) as alternatives to free PSA (fPSA) and its ratio to tPSA in differentiating prostate cancer (PCa) and benign prostatic hyperplasia (BPH) in patients with tPSA of 2–20 μg/L. Methods: PSA in serum of 183 untreated patients with PCa and 132 patients with BPH was measured retrospectively on the chemiluminescence immunoassay analyzer LIAISON® (Byk-Sangtec Diagnostica) with the LIAISON tPSA and LIAISON fPSA assays. The nACT-PSA fraction was determined with a prototype assay measuring the residual PSA after precipitation of ACT-PSA with an ACT-precipitating reagent. Results:nACT-PSA was higher than fPSA in samples with fPSA concentrations &lt;1 μg/L but lower in samples with &gt;1 μg/L fPSA. The median ratios of fPSA/tPSA and of nACT-PSA/tPSA were significantly different between patients with BPH and PCa (19.4% vs 12.2% and 17.4% vs 13.0%, respectively). Within the tPSA ranges tested (2–20, 2–10, and 4–10 μg/L), areas under the ROC curves for the fPSA/tPSA ratios were significantly larger than those for nACT-PSA/tPSA. In the tPSA ranges &lt;10 μg/L, the areas under the ROC curves for fPSA/tPSA were significantly larger than those for tPSA, whereas the areas for nACT-PSA/tPSA were not. At decision limits for 95% sensitivity and specificity, both ratios significantly increased specificity and sensitivity, respectively, compared with tPSA, but the fPSA/tPSA ratio showed higher values. Conclusions: nACT-PSA and its ratio to tPSA provide lower diagnostic sensitivity and specificity than fPSA/tPSA. The fPSA/tPSA ratio represents the state-of-the-art method for differentiating between PCa and BPH.

Ozone Therapy for Remaining Symptoms after covid Infection in Male Patients

2021 ◽  
Vol 3 (9) ◽  
pp. 01-03
Author(s):  
Hayriye Alp
Keyword(s):  
Computed Tomography ◽  
Lung Parenchyma ◽  
Case Definition ◽  
Ozone Therapy ◽  
Exclusion Criteria ◽  
Informed Consent Form ◽  
Male Patients ◽  
Coronavirus Infection ◽  
Rule Out

At the end of March, the total number of cases in China, where 3318 people died, is 81.589. The countries with the highest number of approved cases are America (244 thousand), Italy (115 thousand) and Spain (112 thousand), respectively. In Italy, where the largest number of people died, 13 915 people died15 According to the WHO statement on March 3, 2020, the global fatality rate is 3.4. Determination of seasonal respiratory virus or bacteriological factor in samples taken in the patient according to the possible case definition does not rule out the presence of SARS-CoV-2. Patients who received conventional covid treatment in 2021 were included in the study. As exclusion criteria, patients with favism disease and over 100 mg of salicylic acid treatment, and those with ozone and citrus-allergy were excluded from the study. After the informed consent form was signed by the patients, the dose of gamma was increased by 10 in weekly sessions, starting from 10 gamma. major autohomeopathy was applied. The ozone therapy dose was terminated at 40-45 gamma. Peripheral nodular ground glass densities were found in both lung parenchyma in the computed tomography findings of patients receiving Covid-19 treatment before ozone therapy. It was reported in accordance with high-grade thorax computed tomography findings in terms of coronavirus infection. While the patient's complaints decreased after the 3rd session of major autohomeopathy treatment, it was determined that the symptoms decreased a lot in the 5th session.

scholarly journals Ozone Therapy for Remaining Symptoms after covid Infection in Male Patients

2021 ◽  
Vol 3 (9) ◽  
pp. 01-03
Author(s):  
Hayriye Alp
Keyword(s):  
Computed Tomography ◽  
Lung Parenchyma ◽  
Case Definition ◽  
Ozone Therapy ◽  
Exclusion Criteria ◽  
Informed Consent Form ◽  
Male Patients ◽  
Coronavirus Infection ◽  
Rule Out

At the end of March, the total number of cases in China, where 3318 people died, is 81.589. The countries with the highest number of approved cases are America (244 thousand), Italy (115 thousand) and Spain (112 thousand), respectively. In Italy, where the largest number of people died, 13 915 people died15 According to the WHO statement on March 3, 2020, the global fatality rate is 3.4. Determination of seasonal respiratory virus or bacteriological factor in samples taken in the patient according to the possible case definition does not rule out the presence of SARS-CoV-2. Patients who received conventional covid treatment in 2021 were included in the study. As exclusion criteria, patients with favism disease and over 100 mg of salicylic acid treatment, and those with ozone and citrus-allergy were excluded from the study. After the informed consent form was signed by the patients, the dose of gamma was increased by 10 in weekly sessions, starting from 10 gamma. major autohomeopathy was applied. The ozone therapy dose was terminated at 40-45 gamma. Peripheral nodular ground glass densities were found in both lung parenchyma in the computed tomography findings of patients receiving Covid-19 treatment before ozone therapy. It was reported in accordance with high-grade thorax computed tomography findings in terms of coronavirus infection. While the patient's complaints decreased after the 3rd session of major autohomeopathy treatment, it was determined that the symptoms decreased a lot in the 5th session.

Determination of the Activity of Pulmonary Tuberculosis: the Utility of High-Resolution Computed Tomography

2000 ◽  
Vol 42 (5) ◽  
pp. 757
Author(s):  
Myung Hee Chung ◽  
Hae Giu Lee ◽  
Won Jong Yu ◽  
Hong Jun Chung ◽  
Bo Sung Yang ◽  
...  
Keyword(s):  
Computed Tomography ◽  
High Resolution ◽  
Pulmonary Tuberculosis ◽  
High Resolution Computed Tomography

The New Swedish Cyprus Expedition 2010. Excavations at Dromolaxia Vizatzia/Hala Sultan Tekke. Preliminary results

2011 ◽  
Vol 4 ◽  
pp. 69-98 ◽  
Author(s):  
Peter M. Fischer ◽  
Patrik Klingborg ◽  
Fanny Kärfve ◽  
Fredrika Kärfve ◽  
C. Hagberg ◽  
...  
Keyword(s):  
Ground Penetrating Radar ◽  
Main Task ◽  
Phase 2 ◽  
The North ◽  
12Th Century ◽  
Area 6 ◽  
Recent Phase ◽  
The Rich ◽  
Ground Penetrating

Determination of the complete occupational sequence of the site, including investigation of pre-12th century levels which were thoroughly studied by P. Åström since the 1970s, is the main task of the planned project. During the course of the expedition (NSCE11) in spring 2010 a ground-penetrating radar survey (GPR) was carried out at Dromolaxia Vizatzia/Hala Sultan Tekke in Area 6, leading to the discovery of a large Late Cypriote complex. The compound is bordered to the north by a substantial wall, against which nine rooms (so far) could be exposed. Two occupational phases have been verified but there are indications of a third. The suggested functions of the various structures of the most recent phase are: living, working, storage and administration spaces. The rich find contexts point to the production of textiles and metal objects, and the locally produced pottery is generally of a high quality. There are also many imports, mainly from the Mycenaean sphere of culture. The locally produced vessels from Phase 2 include the “Creature krater” which is a masterpiece of a high artistic standard. Another piece of elevated artistry is the piece of a “Warrior vase”.

Methods for the Quantification of Salivary Cortisol and of a-amylase in Biosensors and Portable Devices

2018 ◽  
Vol 68 (12) ◽  
pp. 2857-2859
Author(s):  
Cristina Mihaela Ghiciuc ◽  
Andreea Silvana Szalontay ◽  
Luminita Radulescu ◽  
Sebastian Cozma ◽  
Catalina Elena Lupusoru ◽  
...  
Keyword(s):  
Real Time ◽  
Medical Practice ◽  
Salivary Cortisol ◽  
Clinical Studies ◽  
Large Scale ◽  
Psychological Research ◽  
Portable Devices ◽  
Salivary Amylase ◽  
Specificity And Sensitivity

There is an increasing interest in the analysis of salivary biomarkers for medical practice. The objective of this article was to identify the specificity and sensitivity of quantification methods used in biosensors or portable devices for the determination of salivary cortisol and salivary a-amylase. There are no biosensors and portable devices for salivary amylase and cortisol that are used on a large scale in clinical studies. These devices would be useful in assessing more real-time psychological research in the future.

Biochemical study of attached macroalgae from the Madeira Archipelago and beach-cast macroalgae from the Canary Islands: multivariate analysis to determine bioresource potential

2020 ◽  
Vol 63 (3) ◽  
pp. 283-298
Author(s):  
Nuno Nunes ◽  
Sofia Valente ◽  
Sónia Ferraz ◽  
Maria Carmo Barreto ◽  
Miguel A.A. Pinheiro de Carvalho
Keyword(s):  
Biochemical Study ◽  
Algal Species ◽  
Biochemical Properties ◽  
Total Phenolic ◽  
Total Carotenoids ◽  
The North ◽  
Madeira Archipelago ◽  
Total Carbohydrates ◽  
Beach Cast

AbstractFifteen attached macroalgae from the Madeira Archipelago, comprising three green, three red and nine brown algal species, as well as two beach-cast macroalgal samples, collected along the north shore of Gran Canaria, were assessed for their biochemical properties. The analysis included the determination of total minerals, total carbohydrates, protein, lipids, chlorophyll a, total carotenoids, total phenolic content, fucoxanthin and phycobilins (allophycocyanin, phycocyanin and phycoerythrin). The results showed a high variability of biochemical composition, allowing for the targetting of specific bioresources for particular purposes, including functional foods. This work provides the foundation for a biorefinery strategy implementation plan, for which specific macroalgae may be targeted for valuable and beneficial compounds.

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